LeishMANIAdb
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Rrp15p_putative/Pfam:PF07890

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Rrp15p_putative/Pfam:PF07890
Gene product:
Rrp15p, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WP07_LEIDO
TriTrypDb:
LdBPK_050080.1 , LdCL_050005700 , LDHU3_05.0110
Length:
201

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0030684 preribosome 3 1
GO:0030687 preribosome, large subunit precursor 4 1
GO:0032991 protein-containing complex 1 1
GO:1990904 ribonucleoprotein complex 2 1
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Expansion

Sequence features

A0A3S7WP07
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WP07

Function

Biological processes
TermNameLevelCount
GO:0000460 maturation of 5.8S rRNA 9 1
GO:0000470 maturation of LSU-rRNA 9 1
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006364 rRNA processing 8 12
GO:0006396 RNA processing 6 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0016070 RNA metabolic process 5 12
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 52 56 PF00656 0.281
CLV_NRD_NRD_1 161 163 PF00675 0.342
CLV_NRD_NRD_1 91 93 PF00675 0.432
CLV_PCSK_KEX2_1 22 24 PF00082 0.362
CLV_PCSK_KEX2_1 34 36 PF00082 0.277
CLV_PCSK_KEX2_1 91 93 PF00082 0.386
CLV_PCSK_PC1ET2_1 22 24 PF00082 0.379
CLV_PCSK_PC1ET2_1 34 36 PF00082 0.330
CLV_PCSK_PC1ET2_1 91 93 PF00082 0.415
CLV_PCSK_SKI1_1 172 176 PF00082 0.338
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HYI7 Leptomonas seymouri 77% 99%
A0A0S4JT37 Bodo saltans 47% 90%
A0A1X0P2H2 Trypanosomatidae 50% 86%
A0A3R7MSE6 Trypanosoma rangeli 58% 95%
A4H454 Leishmania braziliensis 88% 100%
A4HSD7 Leishmania infantum 100% 100%
C9ZPX7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 54% 92%
E9AKB2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4QJJ5 Leishmania major 95% 100%
V5BJH6 Trypanosoma cruzi 57% 95%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS