LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7WNZ9_LEIDO
TriTrypDb:
LdBPK_050160.1 * , LdCL_050006500 , LDHU3_05.0200
Length:
513

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WNZ9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNZ9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 105 107 PF00675 0.695
CLV_NRD_NRD_1 210 212 PF00675 0.630
CLV_NRD_NRD_1 249 251 PF00675 0.664
CLV_NRD_NRD_1 415 417 PF00675 0.699
CLV_PCSK_KEX2_1 105 107 PF00082 0.695
CLV_PCSK_KEX2_1 210 212 PF00082 0.630
CLV_PCSK_KEX2_1 249 251 PF00082 0.664
CLV_PCSK_KEX2_1 415 417 PF00082 0.699
CLV_PCSK_KEX2_1 424 426 PF00082 0.574
CLV_PCSK_PC1ET2_1 424 426 PF00082 0.552
CLV_PCSK_SKI1_1 17 21 PF00082 0.575
CLV_PCSK_SKI1_1 416 420 PF00082 0.682
CLV_PCSK_SKI1_1 67 71 PF00082 0.588
DOC_MAPK_gen_1 423 430 PF00069 0.587
DOC_MAPK_MEF2A_6 423 430 PF00069 0.581
DOC_PP1_RVXF_1 262 269 PF00149 0.524
DOC_PP2B_LxvP_1 502 505 PF13499 0.633
DOC_USP7_MATH_1 155 159 PF00917 0.597
DOC_USP7_MATH_1 174 178 PF00917 0.723
DOC_USP7_MATH_1 312 316 PF00917 0.605
DOC_USP7_MATH_1 406 410 PF00917 0.586
DOC_USP7_MATH_1 480 484 PF00917 0.754
DOC_USP7_MATH_1 505 509 PF00917 0.557
DOC_WW_Pin1_4 165 170 PF00397 0.817
DOC_WW_Pin1_4 213 218 PF00397 0.689
DOC_WW_Pin1_4 233 238 PF00397 0.672
DOC_WW_Pin1_4 447 452 PF00397 0.661
DOC_WW_Pin1_4 471 476 PF00397 0.699
DOC_WW_Pin1_4 489 494 PF00397 0.615
LIG_APCC_ABBAyCdc20_2 5 11 PF00400 0.707
LIG_CaM_IQ_9 53 69 PF13499 0.537
LIG_eIF4E_1 186 192 PF01652 0.568
LIG_FHA_2 154 160 PF00498 0.716
LIG_FHA_2 280 286 PF00498 0.654
LIG_FHA_2 291 297 PF00498 0.465
LIG_FHA_2 363 369 PF00498 0.577
LIG_FHA_2 58 64 PF00498 0.641
LIG_FHA_2 94 100 PF00498 0.575
LIG_IRF3_LxIS_1 174 181 PF10401 0.563
LIG_LIR_Gen_1 267 273 PF02991 0.441
LIG_LIR_Nem_3 200 205 PF02991 0.607
LIG_LIR_Nem_3 267 271 PF02991 0.445
LIG_SH2_STAP1 388 392 PF00017 0.487
LIG_SH2_STAP1 487 491 PF00017 0.725
LIG_SH3_1 211 217 PF00018 0.662
LIG_SH3_2 152 157 PF14604 0.752
LIG_SH3_3 149 155 PF00018 0.784
LIG_SH3_3 166 172 PF00018 0.568
LIG_SH3_3 211 217 PF00018 0.711
LIG_SH3_3 474 480 PF00018 0.656
LIG_SUMO_SIM_anti_2 267 273 PF11976 0.625
LIG_TRAF2_1 226 229 PF00917 0.740
LIG_TRAF2_1 282 285 PF00917 0.654
LIG_TRAF2_1 365 368 PF00917 0.617
LIG_WRC_WIRS_1 265 270 PF05994 0.525
MOD_CK1_1 104 110 PF00069 0.692
MOD_CK1_1 142 148 PF00069 0.831
MOD_CK1_1 168 174 PF00069 0.751
MOD_CK1_1 236 242 PF00069 0.615
MOD_CK1_1 443 449 PF00069 0.693
MOD_CK1_1 450 456 PF00069 0.661
MOD_CK1_1 471 477 PF00069 0.777
MOD_CK1_1 485 491 PF00069 0.702
MOD_CK2_1 104 110 PF00069 0.653
MOD_CK2_1 279 285 PF00069 0.649
MOD_CK2_1 290 296 PF00069 0.463
MOD_CK2_1 362 368 PF00069 0.509
MOD_CK2_1 57 63 PF00069 0.639
MOD_GlcNHglycan 120 123 PF01048 0.695
MOD_GlcNHglycan 144 147 PF01048 0.844
MOD_GlcNHglycan 180 183 PF01048 0.720
MOD_GlcNHglycan 233 236 PF01048 0.699
MOD_GlcNHglycan 314 317 PF01048 0.563
MOD_GlcNHglycan 403 406 PF01048 0.594
MOD_GlcNHglycan 453 456 PF01048 0.794
MOD_GlcNHglycan 484 487 PF01048 0.689
MOD_GlcNHglycan 506 510 PF01048 0.604
MOD_GSK3_1 137 144 PF00069 0.832
MOD_GSK3_1 170 177 PF00069 0.730
MOD_GSK3_1 260 267 PF00069 0.548
MOD_GSK3_1 323 330 PF00069 0.569
MOD_GSK3_1 358 365 PF00069 0.527
MOD_GSK3_1 443 450 PF00069 0.617
MOD_GSK3_1 467 474 PF00069 0.739
MOD_GSK3_1 481 488 PF00069 0.690
MOD_GSK3_1 494 501 PF00069 0.649
MOD_GSK3_1 505 512 PF00069 0.522
MOD_N-GLC_1 123 128 PF02516 0.814
MOD_N-GLC_1 337 342 PF02516 0.646
MOD_N-GLC_2 434 436 PF02516 0.456
MOD_NEK2_1 139 144 PF00069 0.744
MOD_NEK2_1 192 197 PF00069 0.683
MOD_NEK2_1 231 236 PF00069 0.732
MOD_NEK2_1 370 375 PF00069 0.553
MOD_NEK2_1 440 445 PF00069 0.588
MOD_NEK2_1 456 461 PF00069 0.681
MOD_NEK2_1 498 503 PF00069 0.714
MOD_NEK2_2 111 116 PF00069 0.544
MOD_NEK2_2 290 295 PF00069 0.643
MOD_PIKK_1 139 145 PF00454 0.820
MOD_PIKK_1 192 198 PF00454 0.579
MOD_PIKK_1 73 79 PF00454 0.571
MOD_PKA_2 104 110 PF00069 0.669
MOD_PKA_2 306 312 PF00069 0.649
MOD_Plk_4 111 117 PF00069 0.638
MOD_Plk_4 498 504 PF00069 0.727
MOD_ProDKin_1 165 171 PF00069 0.817
MOD_ProDKin_1 213 219 PF00069 0.692
MOD_ProDKin_1 233 239 PF00069 0.663
MOD_ProDKin_1 447 453 PF00069 0.664
MOD_ProDKin_1 471 477 PF00069 0.693
MOD_ProDKin_1 489 495 PF00069 0.615
MOD_SUMO_rev_2 256 266 PF00179 0.492
MOD_SUMO_rev_2 54 62 PF00179 0.588
TRG_ER_diArg_1 209 211 PF00400 0.640
TRG_ER_diArg_1 248 250 PF00400 0.686
TRG_ER_diArg_1 414 416 PF00400 0.699
TRG_Pf-PMV_PEXEL_1 281 285 PF00026 0.550
TRG_Pf-PMV_PEXEL_1 67 71 PF00026 0.687
TRG_Pf-PMV_PEXEL_1 95 99 PF00026 0.636

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKE8 Leptomonas seymouri 37% 97%
A4H462 Leishmania braziliensis 67% 100%
A4HSD1 Leishmania infantum 99% 100%
E9AKC0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
Q4QJI7 Leishmania major 86% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS