LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WNX8_LEIDO
TriTrypDb:
LdBPK_041160.1 * , LdCL_040017200 , LDHU3_04.1410
Length:
168

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WNX8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNX8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 74 78 PF00656 0.615
CLV_NRD_NRD_1 160 162 PF00675 0.681
CLV_PCSK_KEX2_1 160 162 PF00082 0.665
CLV_PCSK_KEX2_1 70 72 PF00082 0.530
CLV_PCSK_PC1ET2_1 70 72 PF00082 0.577
CLV_PCSK_PC7_1 66 72 PF00082 0.574
CLV_PCSK_SKI1_1 139 143 PF00082 0.617
CLV_PCSK_SKI1_1 154 158 PF00082 0.463
CLV_PCSK_SKI1_1 89 93 PF00082 0.616
DEG_COP1_1 90 99 PF00400 0.604
DOC_CYCLIN_RxL_1 151 159 PF00134 0.565
DOC_MAPK_gen_1 19 27 PF00069 0.473
DOC_PP4_FxxP_1 5 8 PF00568 0.605
DOC_WW_Pin1_4 143 148 PF00397 0.531
DOC_WW_Pin1_4 162 167 PF00397 0.689
DOC_WW_Pin1_4 89 94 PF00397 0.650
LIG_14-3-3_CanoR_1 108 113 PF00244 0.623
LIG_14-3-3_CanoR_1 139 149 PF00244 0.673
LIG_FHA_1 42 48 PF00498 0.575
LIG_LIR_Gen_1 15 25 PF02991 0.485
LIG_LIR_Nem_3 101 107 PF02991 0.681
LIG_LIR_Nem_3 15 20 PF02991 0.490
LIG_SH2_CRK 104 108 PF00017 0.618
LIG_SH2_STAT5 95 98 PF00017 0.595
LIG_SH3_3 94 100 PF00018 0.725
MOD_CK1_1 129 135 PF00069 0.581
MOD_CK1_1 15 21 PF00069 0.498
MOD_CMANNOS 46 49 PF00535 0.486
MOD_GlcNHglycan 100 103 PF01048 0.691
MOD_GlcNHglycan 114 119 PF01048 0.460
MOD_NEK2_1 156 161 PF00069 0.534
MOD_PKA_2 49 55 PF00069 0.544
MOD_Plk_4 12 18 PF00069 0.569
MOD_Plk_4 91 97 PF00069 0.719
MOD_ProDKin_1 143 149 PF00069 0.529
MOD_ProDKin_1 162 168 PF00069 0.700
MOD_ProDKin_1 89 95 PF00069 0.652
MOD_SUMO_for_1 141 144 PF00179 0.684
TRG_DiLeu_BaEn_1 115 120 PF01217 0.542
TRG_ENDOCYTIC_2 104 107 PF00928 0.630
TRG_ER_diArg_1 160 162 PF00400 0.681
TRG_ER_diArg_1 83 86 PF00400 0.557

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P452 Leptomonas seymouri 79% 100%
A0A1X0NLB3 Trypanosomatidae 56% 100%
A4H429 Leishmania braziliensis 90% 100%
A4HSB3 Leishmania infantum 100% 100%
E9AK96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
O97194 Leishmania major 97% 100%
V5DEI9 Trypanosoma cruzi 63% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS