LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WNW8_LEIDO
TriTrypDb:
LdBPK_041110.1 , LdCL_040016700 , LDHU3_04.1360
Length:
109

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WNW8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNW8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 30 32 PF00675 0.416
CLV_NRD_NRD_1 65 67 PF00675 0.422
CLV_PCSK_KEX2_1 30 32 PF00082 0.389
CLV_PCSK_KEX2_1 65 67 PF00082 0.480
CLV_PCSK_KEX2_1 82 84 PF00082 0.392
CLV_PCSK_PC1ET2_1 82 84 PF00082 0.453
CLV_PCSK_SKI1_1 31 35 PF00082 0.414
CLV_PCSK_SKI1_1 65 69 PF00082 0.467
DEG_APCC_DBOX_1 35 43 PF00400 0.422
DOC_MAPK_gen_1 30 39 PF00069 0.393
DOC_USP7_MATH_1 103 107 PF00917 0.549
DOC_USP7_UBL2_3 34 38 PF12436 0.430
LIG_Actin_RPEL_3 24 43 PF02755 0.417
LIG_BIR_II_1 1 5 PF00653 0.559
LIG_FHA_1 18 24 PF00498 0.402
LIG_Pex14_2 57 61 PF04695 0.383
LIG_REV1ctd_RIR_1 15 23 PF16727 0.472
LIG_SH2_CRK 101 105 PF00017 0.505
LIG_SH2_STAT5 85 88 PF00017 0.385
LIG_SH2_STAT5 90 93 PF00017 0.364
LIG_SUMO_SIM_par_1 38 44 PF11976 0.419
MOD_GlcNHglycan 43 46 PF01048 0.437
MOD_NEK2_1 1 6 PF00069 0.491
MOD_SUMO_for_1 18 21 PF00179 0.444
MOD_SUMO_for_1 57 60 PF00179 0.383
MOD_SUMO_rev_2 27 35 PF00179 0.445
TRG_ENDOCYTIC_2 101 104 PF00928 0.498
TRG_ER_diArg_1 65 67 PF00400 0.528
TRG_Pf-PMV_PEXEL_1 66 70 PF00026 0.467

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HVA0 Leptomonas seymouri 66% 90%
A0A1X0NLG7 Trypanosomatidae 53% 95%
A4H425 Leishmania braziliensis 77% 100%
A4HSA8 Leishmania infantum 100% 100%
E9AK91 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS