Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WNU9_LEIDO

TriTrypDb:

LdBPK_040910.1 , LdCL_040014700 , LDHU3_04.1140

Length:

247

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WNU9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNU9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.576
CLV_PCSK_KEX2_1	35	37	PF00082	0.416
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.416
CLV_PCSK_SKI1_1	36	40	PF00082	0.417
DEG_APCC_DBOX_1	229	237	PF00400	0.406
DEG_SPOP_SBC_1	97	101	PF00917	0.608
DOC_CKS1_1	172	177	PF01111	0.581
DOC_MAPK_gen_1	35	41	PF00069	0.425
DOC_MAPK_MEF2A_6	178	187	PF00069	0.447
DOC_MAPK_MEF2A_6	197	206	PF00069	0.347
DOC_PP2B_LxvP_1	183	186	PF13499	0.450
DOC_PP2B_LxvP_1	92	95	PF13499	0.663
DOC_USP7_MATH_1	110	114	PF00917	0.581
DOC_USP7_MATH_1	14	18	PF00917	0.555
DOC_USP7_MATH_1	144	148	PF00917	0.635
DOC_USP7_MATH_1	186	190	PF00917	0.478
DOC_USP7_MATH_1	44	48	PF00917	0.511
DOC_USP7_MATH_1	97	101	PF00917	0.672
DOC_WW_Pin1_4	167	172	PF00397	0.631
DOC_WW_Pin1_4	173	178	PF00397	0.642
DOC_WW_Pin1_4	64	69	PF00397	0.748
LIG_14-3-3_CanoR_1	226	234	PF00244	0.441
LIG_14-3-3_CanoR_1	5	10	PF00244	0.580
LIG_BIR_II_1	1	5	PF00653	0.647
LIG_FHA_1	16	22	PF00498	0.613
LIG_LIR_Gen_1	147	156	PF02991	0.654
LIG_LIR_Gen_1	200	209	PF02991	0.388
LIG_LIR_Gen_1	25	33	PF02991	0.389
LIG_LIR_LC3C_4	200	204	PF02991	0.395
LIG_LIR_Nem_3	147	151	PF02991	0.632
LIG_LIR_Nem_3	200	204	PF02991	0.380
LIG_LIR_Nem_3	25	29	PF02991	0.394
LIG_PDZ_Class_2	242	247	PF00595	0.384
LIG_PROFILIN_1	160	166	PF00235	0.546
LIG_SH2_CRK	148	152	PF00017	0.647
LIG_SH2_NCK_1	148	152	PF00017	0.647
LIG_SH2_PTP2	26	29	PF00017	0.378
LIG_SH2_STAP1	148	152	PF00017	0.550
LIG_SH2_STAT5	214	217	PF00017	0.548
LIG_SH2_STAT5	26	29	PF00017	0.378
LIG_SH2_STAT5	58	61	PF00017	0.525
LIG_SH3_3	115	121	PF00018	0.650
LIG_SH3_3	157	163	PF00018	0.621
LIG_SH3_3	169	175	PF00018	0.492
LIG_TYR_ITIM	24	29	PF00017	0.403
MOD_CDK_SPK_2	173	178	PF00069	0.552
MOD_CDK_SPxxK_3	171	178	PF00069	0.549
MOD_CK1_1	189	195	PF00069	0.394
MOD_CK1_1	25	31	PF00069	0.460
MOD_CK1_1	4	10	PF00069	0.575
MOD_CK1_1	99	105	PF00069	0.644
MOD_CK2_1	151	157	PF00069	0.544
MOD_Cter_Amidation	33	36	PF01082	0.374
MOD_GlcNHglycan	101	104	PF01048	0.665
MOD_GlcNHglycan	112	115	PF01048	0.555
MOD_GSK3_1	1	8	PF00069	0.639
MOD_GSK3_1	167	174	PF00069	0.650
MOD_GSK3_1	186	193	PF00069	0.408
MOD_GSK3_1	97	104	PF00069	0.662
MOD_NEK2_1	1	6	PF00069	0.589
MOD_NEK2_1	166	171	PF00069	0.662
MOD_NEK2_1	190	195	PF00069	0.401
MOD_PKA_2	225	231	PF00069	0.448
MOD_PKA_2	4	10	PF00069	0.575
MOD_Plk_1	190	196	PF00069	0.393
MOD_Plk_2-3	225	231	PF00069	0.479
MOD_Plk_4	191	197	PF00069	0.488
MOD_Plk_4	22	28	PF00069	0.445
MOD_ProDKin_1	167	173	PF00069	0.630
MOD_ProDKin_1	64	70	PF00069	0.756
MOD_SUMO_rev_2	113	118	PF00179	0.682
MOD_SUMO_rev_2	28	37	PF00179	0.403
TRG_DiLeu_BaEn_1	191	196	PF01217	0.490
TRG_DiLeu_BaEn_1	229	234	PF01217	0.532
TRG_DiLeu_BaLyEn_6	162	167	PF01217	0.624
TRG_DiLeu_BaLyEn_6	178	183	PF01217	0.637
TRG_ENDOCYTIC_2	148	151	PF00928	0.649
TRG_ENDOCYTIC_2	26	29	PF00928	0.378

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P497	Leptomonas seymouri	49%	100%
A4H3Y4	Leishmania braziliensis	72%	100%
A4HS84	Leishmania infantum	99%	100%
E9AK72	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
O97008	Leishmania major	92%	100%