LeishMANIAdb
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WASH_WAHD domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
WASH_WAHD domain-containing protein
Gene product:
hypothetical protein, conserved (fragment)
Species:
Leishmania donovani
UniProt:
A0A3S7WNR6_LEIDO
TriTrypDb:
LdBPK_040740.1 * , LdCL_040013000 , LDHU3_04.0960
Length:
815

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WNR6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNR6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 20 24 PF00656 0.608
CLV_C14_Caspase3-7 368 372 PF00656 0.569
CLV_C14_Caspase3-7 774 778 PF00656 0.808
CLV_NRD_NRD_1 113 115 PF00675 0.404
CLV_NRD_NRD_1 181 183 PF00675 0.776
CLV_NRD_NRD_1 463 465 PF00675 0.771
CLV_NRD_NRD_1 501 503 PF00675 0.817
CLV_NRD_NRD_1 505 507 PF00675 0.749
CLV_NRD_NRD_1 523 525 PF00675 0.567
CLV_NRD_NRD_1 527 529 PF00675 0.827
CLV_NRD_NRD_1 555 557 PF00675 0.702
CLV_NRD_NRD_1 744 746 PF00675 0.827
CLV_NRD_NRD_1 770 772 PF00675 0.695
CLV_NRD_NRD_1 91 93 PF00675 0.466
CLV_NRD_NRD_1 98 100 PF00675 0.373
CLV_PCSK_FUR_1 111 115 PF00082 0.466
CLV_PCSK_FUR_1 179 183 PF00082 0.777
CLV_PCSK_FUR_1 521 525 PF00082 0.683
CLV_PCSK_KEX2_1 113 115 PF00082 0.341
CLV_PCSK_KEX2_1 181 183 PF00082 0.776
CLV_PCSK_KEX2_1 463 465 PF00082 0.771
CLV_PCSK_KEX2_1 501 503 PF00082 0.814
CLV_PCSK_KEX2_1 505 507 PF00082 0.746
CLV_PCSK_KEX2_1 523 525 PF00082 0.570
CLV_PCSK_KEX2_1 526 528 PF00082 0.831
CLV_PCSK_KEX2_1 554 556 PF00082 0.709
CLV_PCSK_KEX2_1 743 745 PF00082 0.825
CLV_PCSK_KEX2_1 770 772 PF00082 0.729
CLV_PCSK_KEX2_1 91 93 PF00082 0.466
CLV_PCSK_KEX2_1 98 100 PF00082 0.373
CLV_PCSK_PC7_1 501 507 PF00082 0.810
CLV_PCSK_PC7_1 523 529 PF00082 0.849
CLV_PCSK_PC7_1 550 556 PF00082 0.709
CLV_PCSK_SKI1_1 143 147 PF00082 0.769
CLV_PCSK_SKI1_1 402 406 PF00082 0.580
CLV_PCSK_SKI1_1 444 448 PF00082 0.806
CLV_PCSK_SKI1_1 744 748 PF00082 0.774
DEG_APCC_DBOX_1 443 451 PF00400 0.734
DEG_Nend_UBRbox_2 1 3 PF02207 0.615
DEG_SPOP_SBC_1 315 319 PF00917 0.740
DEG_SPOP_SBC_1 365 369 PF00917 0.656
DOC_CDC14_PxL_1 39 47 PF14671 0.675
DOC_CKS1_1 421 426 PF01111 0.729
DOC_MAPK_gen_1 122 131 PF00069 0.702
DOC_PP2B_LxvP_1 45 48 PF13499 0.667
DOC_PP2B_LxvP_1 580 583 PF13499 0.798
DOC_PP2B_LxvP_1 590 593 PF13499 0.731
DOC_PP4_FxxP_1 177 180 PF00568 0.778
DOC_PP4_FxxP_1 421 424 PF00568 0.732
DOC_USP7_MATH_1 180 184 PF00917 0.840
DOC_USP7_MATH_1 223 227 PF00917 0.690
DOC_USP7_MATH_1 315 319 PF00917 0.723
DOC_USP7_MATH_1 349 353 PF00917 0.768
DOC_USP7_MATH_1 365 369 PF00917 0.530
DOC_USP7_MATH_1 377 381 PF00917 0.600
DOC_USP7_MATH_1 439 443 PF00917 0.714
DOC_USP7_MATH_1 48 52 PF00917 0.663
DOC_USP7_MATH_1 60 64 PF00917 0.499
DOC_USP7_MATH_1 626 630 PF00917 0.769
DOC_USP7_MATH_1 651 655 PF00917 0.665
DOC_USP7_MATH_1 663 667 PF00917 0.749
DOC_USP7_MATH_1 681 685 PF00917 0.618
DOC_USP7_MATH_1 694 698 PF00917 0.698
DOC_USP7_MATH_1 735 739 PF00917 0.770
DOC_USP7_MATH_1 773 777 PF00917 0.769
DOC_USP7_MATH_1 804 808 PF00917 0.826
DOC_USP7_MATH_1 85 89 PF00917 0.499
DOC_WW_Pin1_4 181 186 PF00397 0.767
DOC_WW_Pin1_4 251 256 PF00397 0.749
DOC_WW_Pin1_4 382 387 PF00397 0.635
DOC_WW_Pin1_4 390 395 PF00397 0.673
DOC_WW_Pin1_4 420 425 PF00397 0.652
LIG_14-3-3_CanoR_1 111 119 PF00244 0.449
LIG_14-3-3_CanoR_1 141 146 PF00244 0.588
LIG_14-3-3_CanoR_1 179 185 PF00244 0.772
LIG_14-3-3_CanoR_1 233 242 PF00244 0.760
LIG_14-3-3_CanoR_1 600 605 PF00244 0.803
LIG_BRCT_BRCA1_1 173 177 PF00533 0.831
LIG_CtBP_PxDLS_1 587 591 PF00389 0.728
LIG_FHA_1 113 119 PF00498 0.466
LIG_FHA_1 273 279 PF00498 0.757
LIG_FHA_1 34 40 PF00498 0.666
LIG_FHA_1 410 416 PF00498 0.687
LIG_FHA_1 420 426 PF00498 0.535
LIG_FHA_1 611 617 PF00498 0.626
LIG_FHA_1 735 741 PF00498 0.744
LIG_FHA_2 115 121 PF00498 0.533
LIG_FHA_2 478 484 PF00498 0.802
LIG_FHA_2 534 540 PF00498 0.782
LIG_FHA_2 75 81 PF00498 0.316
LIG_LIR_Apic_2 174 180 PF02991 0.773
LIG_LIR_Apic_2 214 218 PF02991 0.782
LIG_LIR_Apic_2 385 391 PF02991 0.600
LIG_LIR_Apic_2 420 424 PF02991 0.646
LIG_LIR_Gen_1 510 516 PF02991 0.609
LIG_LIR_Nem_3 510 514 PF02991 0.614
LIG_LYPXL_yS_3 125 128 PF13949 0.554
LIG_MYND_1 126 130 PF01753 0.558
LIG_MYND_1 588 592 PF01753 0.724
LIG_MYND_1 608 612 PF01753 0.719
LIG_PROFILIN_1 605 611 PF00235 0.779
LIG_PROFILIN_1 642 648 PF00235 0.663
LIG_PROFILIN_1 668 674 PF00235 0.692
LIG_PROFILIN_1 688 694 PF00235 0.621
LIG_PROFILIN_1 719 725 PF00235 0.776
LIG_RPA_C_Fungi 550 562 PF08784 0.708
LIG_SH2_CRK 215 219 PF00017 0.778
LIG_SH2_CRK 430 434 PF00017 0.754
LIG_SH2_NCK_1 34 38 PF00017 0.669
LIG_SH2_SRC 215 218 PF00017 0.711
LIG_SH2_STAP1 34 38 PF00017 0.669
LIG_SH3_1 182 188 PF00018 0.763
LIG_SH3_1 388 394 PF00018 0.576
LIG_SH3_1 636 642 PF00018 0.765
LIG_SH3_1 667 673 PF00018 0.621
LIG_SH3_1 717 723 PF00018 0.783
LIG_SH3_3 120 126 PF00018 0.533
LIG_SH3_3 127 133 PF00018 0.699
LIG_SH3_3 182 188 PF00018 0.820
LIG_SH3_3 207 213 PF00018 0.725
LIG_SH3_3 249 255 PF00018 0.820
LIG_SH3_3 348 354 PF00018 0.806
LIG_SH3_3 388 394 PF00018 0.576
LIG_SH3_3 581 587 PF00018 0.805
LIG_SH3_3 589 595 PF00018 0.718
LIG_SH3_3 602 608 PF00018 0.610
LIG_SH3_3 617 623 PF00018 0.787
LIG_SH3_3 632 638 PF00018 0.663
LIG_SH3_3 639 645 PF00018 0.660
LIG_SH3_3 665 671 PF00018 0.775
LIG_SH3_3 685 691 PF00018 0.728
LIG_SH3_3 707 713 PF00018 0.732
LIG_SH3_3 715 721 PF00018 0.671
LIG_SUMO_SIM_par_1 274 279 PF11976 0.758
LIG_TRAF2_1 516 519 PF00917 0.696
LIG_UBA3_1 656 661 PF00899 0.715
LIG_WW_2 608 611 PF00397 0.783
LIG_WW_3 633 637 PF00397 0.724
LIG_WW_3 783 787 PF00397 0.646
MOD_CDK_SPxxK_3 382 389 PF00069 0.619
MOD_CK1_1 11 17 PF00069 0.680
MOD_CK1_1 167 173 PF00069 0.745
MOD_CK1_1 192 198 PF00069 0.791
MOD_CK1_1 231 237 PF00069 0.626
MOD_CK1_1 250 256 PF00069 0.689
MOD_CK1_1 3 9 PF00069 0.737
MOD_CK1_1 316 322 PF00069 0.742
MOD_CK1_1 411 417 PF00069 0.615
MOD_CK1_1 479 485 PF00069 0.849
MOD_CK1_1 51 57 PF00069 0.667
MOD_CK1_1 535 541 PF00069 0.765
MOD_CK1_1 682 688 PF00069 0.594
MOD_CK1_1 728 734 PF00069 0.804
MOD_CK1_1 752 758 PF00069 0.777
MOD_CK1_1 775 781 PF00069 0.785
MOD_CK1_1 807 813 PF00069 0.792
MOD_CK2_1 114 120 PF00069 0.466
MOD_CK2_1 477 483 PF00069 0.776
MOD_CK2_1 533 539 PF00069 0.804
MOD_Cter_Amidation 111 114 PF01082 0.466
MOD_GlcNHglycan 10 14 PF01048 0.717
MOD_GlcNHglycan 162 165 PF01048 0.740
MOD_GlcNHglycan 166 169 PF01048 0.629
MOD_GlcNHglycan 194 197 PF01048 0.813
MOD_GlcNHglycan 225 228 PF01048 0.757
MOD_GlcNHglycan 281 286 PF01048 0.763
MOD_GlcNHglycan 318 321 PF01048 0.731
MOD_GlcNHglycan 347 350 PF01048 0.790
MOD_GlcNHglycan 402 405 PF01048 0.640
MOD_GlcNHglycan 5 8 PF01048 0.737
MOD_GlcNHglycan 50 53 PF01048 0.710
MOD_GlcNHglycan 557 560 PF01048 0.695
MOD_GlcNHglycan 580 583 PF01048 0.738
MOD_GlcNHglycan 62 65 PF01048 0.480
MOD_GlcNHglycan 628 631 PF01048 0.779
MOD_GlcNHglycan 663 666 PF01048 0.818
MOD_GlcNHglycan 730 733 PF01048 0.766
MOD_GlcNHglycan 756 759 PF01048 0.828
MOD_GlcNHglycan 781 784 PF01048 0.642
MOD_GlcNHglycan 797 800 PF01048 0.802
MOD_GSK3_1 1 8 PF00069 0.744
MOD_GSK3_1 114 121 PF00069 0.464
MOD_GSK3_1 12 19 PF00069 0.660
MOD_GSK3_1 160 167 PF00069 0.766
MOD_GSK3_1 190 197 PF00069 0.789
MOD_GSK3_1 247 254 PF00069 0.720
MOD_GSK3_1 299 306 PF00069 0.704
MOD_GSK3_1 309 316 PF00069 0.693
MOD_GSK3_1 345 352 PF00069 0.715
MOD_GSK3_1 400 407 PF00069 0.736
MOD_GSK3_1 47 54 PF00069 0.720
MOD_GSK3_1 473 480 PF00069 0.729
MOD_GSK3_1 538 545 PF00069 0.769
MOD_GSK3_1 569 576 PF00069 0.793
MOD_GSK3_1 596 603 PF00069 0.862
MOD_GSK3_1 60 67 PF00069 0.480
MOD_GSK3_1 651 658 PF00069 0.816
MOD_GSK3_1 731 738 PF00069 0.806
MOD_GSK3_1 749 756 PF00069 0.627
MOD_GSK3_1 772 779 PF00069 0.777
MOD_GSK3_1 804 811 PF00069 0.815
MOD_N-GLC_1 250 255 PF02516 0.594
MOD_N-GLC_1 338 343 PF02516 0.692
MOD_NEK2_1 1 6 PF00069 0.707
MOD_NEK2_1 118 123 PF00069 0.533
MOD_NEK2_1 267 272 PF00069 0.729
MOD_NEK2_1 397 402 PF00069 0.697
MOD_NEK2_1 409 414 PF00069 0.594
MOD_NEK2_1 795 800 PF00069 0.812
MOD_NEK2_2 299 304 PF00069 0.578
MOD_PIKK_1 144 150 PF00454 0.712
MOD_PIKK_1 570 576 PF00454 0.806
MOD_PIKK_1 725 731 PF00454 0.687
MOD_PIKK_1 85 91 PF00454 0.466
MOD_PKA_1 113 119 PF00069 0.399
MOD_PKA_1 501 507 PF00069 0.810
MOD_PKA_1 555 561 PF00069 0.706
MOD_PKA_2 112 118 PF00069 0.493
MOD_PKA_2 17 23 PF00069 0.730
MOD_PKA_2 180 186 PF00069 0.769
MOD_PKA_2 303 309 PF00069 0.757
MOD_PKA_2 501 507 PF00069 0.803
MOD_PKA_2 555 561 PF00069 0.806
MOD_PKA_2 568 574 PF00069 0.638
MOD_PKA_2 599 605 PF00069 0.803
MOD_PKB_1 111 119 PF00069 0.399
MOD_Plk_1 1 7 PF00069 0.690
MOD_Plk_1 231 237 PF00069 0.564
MOD_Plk_1 281 287 PF00069 0.668
MOD_Plk_4 114 120 PF00069 0.466
MOD_Plk_4 272 278 PF00069 0.754
MOD_Plk_4 303 309 PF00069 0.691
MOD_Plk_4 735 741 PF00069 0.744
MOD_Plk_4 74 80 PF00069 0.433
MOD_ProDKin_1 181 187 PF00069 0.764
MOD_ProDKin_1 251 257 PF00069 0.747
MOD_ProDKin_1 382 388 PF00069 0.636
MOD_ProDKin_1 390 396 PF00069 0.673
MOD_ProDKin_1 420 426 PF00069 0.649
MOD_SUMO_rev_2 116 123 PF00179 0.399
MOD_SUMO_rev_2 654 663 PF00179 0.715
TRG_DiLeu_BaEn_4 281 287 PF01217 0.518
TRG_ENDOCYTIC_2 125 128 PF00928 0.554
TRG_ENDOCYTIC_2 360 363 PF00928 0.753
TRG_ENDOCYTIC_2 430 433 PF00928 0.754
TRG_ER_diArg_1 110 113 PF00400 0.213
TRG_ER_diArg_1 133 136 PF00400 0.659
TRG_ER_diArg_1 178 181 PF00400 0.779
TRG_ER_diArg_1 462 464 PF00400 0.763
TRG_ER_diArg_1 521 524 PF00400 0.766
TRG_ER_diArg_1 526 528 PF00400 0.725
TRG_ER_diArg_1 554 556 PF00400 0.779
TRG_ER_diArg_1 560 563 PF00400 0.759
TRG_ER_diArg_1 743 745 PF00400 0.763
TRG_ER_diArg_1 792 795 PF00400 0.810
TRG_ER_diArg_1 91 93 PF00400 0.466
TRG_ER_diArg_1 98 100 PF00400 0.373
TRG_Pf-PMV_PEXEL_1 444 449 PF00026 0.807
TRG_Pf-PMV_PEXEL_1 452 457 PF00026 0.661
TRG_Pf-PMV_PEXEL_1 655 659 PF00026 0.712
TRG_Pf-PMV_PEXEL_1 745 750 PF00026 0.787

Homologs

Protein Taxonomy Sequence identity Coverage
A4H408 Leishmania braziliensis 69% 100%
A4HS70 Leishmania infantum 98% 100%
E9AK57 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
O97214 Leishmania major 88% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS