LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WNR0_LEIDO
TriTrypDb:
LdBPK_040520.1 , LdCL_040010700 , LDHU3_04.0690
Length:
347

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WNR0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNR0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 70 74 PF00656 0.538
CLV_MEL_PAP_1 34 40 PF00089 0.552
CLV_NRD_NRD_1 143 145 PF00675 0.535
CLV_NRD_NRD_1 262 264 PF00675 0.412
CLV_NRD_NRD_1 288 290 PF00675 0.574
CLV_NRD_NRD_1 340 342 PF00675 0.566
CLV_PCSK_KEX2_1 262 264 PF00082 0.412
CLV_PCSK_KEX2_1 288 290 PF00082 0.574
CLV_PCSK_KEX2_1 342 344 PF00082 0.580
CLV_PCSK_PC1ET2_1 342 344 PF00082 0.580
CLV_PCSK_SKI1_1 144 148 PF00082 0.418
CLV_PCSK_SKI1_1 262 266 PF00082 0.534
CLV_PCSK_SKI1_1 288 292 PF00082 0.568
DEG_APCC_DBOX_1 261 269 PF00400 0.577
DEG_SPOP_SBC_1 184 188 PF00917 0.642
DEG_SPOP_SBC_1 89 93 PF00917 0.640
DOC_CDC14_PxL_1 108 116 PF14671 0.514
DOC_CKS1_1 221 226 PF01111 0.587
DOC_CYCLIN_RxL_1 256 266 PF00134 0.506
DOC_CYCLIN_yCln2_LP_2 290 296 PF00134 0.556
DOC_PP2B_LxvP_1 290 293 PF13499 0.591
DOC_PP2B_LxvP_1 52 55 PF13499 0.714
DOC_PP2B_LxvP_1 66 69 PF13499 0.540
DOC_USP7_MATH_1 176 180 PF00917 0.762
DOC_USP7_MATH_1 184 188 PF00917 0.646
DOC_USP7_MATH_1 201 205 PF00917 0.556
DOC_USP7_MATH_1 21 25 PF00917 0.648
DOC_USP7_MATH_1 26 30 PF00917 0.650
DOC_USP7_MATH_1 299 303 PF00917 0.625
DOC_USP7_MATH_1 4 8 PF00917 0.560
DOC_USP7_MATH_1 81 85 PF00917 0.671
DOC_USP7_MATH_1 89 93 PF00917 0.585
DOC_WW_Pin1_4 197 202 PF00397 0.676
DOC_WW_Pin1_4 220 225 PF00397 0.685
DOC_WW_Pin1_4 45 50 PF00397 0.554
DOC_WW_Pin1_4 90 95 PF00397 0.596
LIG_BIR_III_2 272 276 PF00653 0.535
LIG_CaM_NSCaTE_8 127 134 PF13499 0.406
LIG_CtBP_PxDLS_1 224 228 PF00389 0.445
LIG_deltaCOP1_diTrp_1 124 130 PF00928 0.432
LIG_EH_1 40 44 PF12763 0.466
LIG_FHA_1 126 132 PF00498 0.462
LIG_FHA_1 99 105 PF00498 0.457
LIG_FHA_2 221 227 PF00498 0.578
LIG_FHA_2 295 301 PF00498 0.525
LIG_LIR_Gen_1 124 134 PF02991 0.377
LIG_LIR_Gen_1 27 38 PF02991 0.446
LIG_LIR_Nem_3 124 130 PF02991 0.441
LIG_LIR_Nem_3 27 33 PF02991 0.509
LIG_NRBOX 260 266 PF00104 0.514
LIG_PCNA_PIPBox_1 284 293 PF02747 0.568
LIG_PCNA_yPIPBox_3 281 291 PF02747 0.475
LIG_SH2_CRK 271 275 PF00017 0.634
LIG_SH2_NCK_1 271 275 PF00017 0.634
LIG_SH3_1 53 59 PF00018 0.728
LIG_SH3_3 109 115 PF00018 0.528
LIG_SH3_3 158 164 PF00018 0.754
LIG_SH3_3 166 172 PF00018 0.717
LIG_SH3_3 53 59 PF00018 0.767
LIG_Sin3_3 328 335 PF02671 0.645
LIG_TRAF2_1 164 167 PF00917 0.619
LIG_TRAF2_1 223 226 PF00917 0.460
LIG_TRAF2_1 250 253 PF00917 0.558
LIG_TRAF2_1 275 278 PF00917 0.518
LIG_TRAF2_1 280 283 PF00917 0.488
LIG_WRC_WIRS_1 30 35 PF05994 0.514
MOD_CDK_SPK_2 45 50 PF00069 0.537
MOD_CK1_1 186 192 PF00069 0.595
MOD_CK1_1 204 210 PF00069 0.571
MOD_CK1_1 29 35 PF00069 0.593
MOD_CK1_1 302 308 PF00069 0.680
MOD_CK1_1 310 316 PF00069 0.612
MOD_CK1_1 67 73 PF00069 0.639
MOD_CK1_1 7 13 PF00069 0.577
MOD_CK1_1 93 99 PF00069 0.557
MOD_CK2_1 21 27 PF00069 0.604
MOD_CK2_1 220 226 PF00069 0.496
MOD_CK2_1 247 253 PF00069 0.557
MOD_GlcNHglycan 10 13 PF01048 0.710
MOD_GlcNHglycan 132 135 PF01048 0.578
MOD_GlcNHglycan 23 26 PF01048 0.572
MOD_GlcNHglycan 300 304 PF01048 0.723
MOD_GlcNHglycan 312 315 PF01048 0.531
MOD_GlcNHglycan 69 72 PF01048 0.560
MOD_GlcNHglycan 85 88 PF01048 0.468
MOD_GlcNHglycan 95 98 PF01048 0.470
MOD_GSK3_1 15 22 PF00069 0.580
MOD_GSK3_1 197 204 PF00069 0.689
MOD_GSK3_1 225 232 PF00069 0.557
MOD_GSK3_1 302 309 PF00069 0.662
MOD_GSK3_1 4 11 PF00069 0.700
MOD_GSK3_1 81 88 PF00069 0.589
MOD_GSK3_1 89 96 PF00069 0.532
MOD_NEK2_1 185 190 PF00069 0.718
MOD_NEK2_1 5 10 PF00069 0.613
MOD_NEK2_1 98 103 PF00069 0.563
MOD_PIKK_1 54 60 PF00454 0.660
MOD_PKA_1 341 347 PF00069 0.611
MOD_PKA_2 36 42 PF00069 0.560
MOD_Plk_1 225 231 PF00069 0.461
MOD_Plk_4 29 35 PF00069 0.581
MOD_ProDKin_1 197 203 PF00069 0.677
MOD_ProDKin_1 220 226 PF00069 0.682
MOD_ProDKin_1 45 51 PF00069 0.565
MOD_ProDKin_1 90 96 PF00069 0.585
MOD_SUMO_rev_2 334 344 PF00179 0.521
TRG_AP2beta_CARGO_1 27 37 PF09066 0.454
TRG_DiLeu_BaLyEn_6 109 114 PF01217 0.515
TRG_DiLeu_BaLyEn_6 260 265 PF01217 0.428
TRG_ENDOCYTIC_2 271 274 PF00928 0.661
TRG_ER_diArg_1 261 263 PF00400 0.432
TRG_ER_diArg_1 287 289 PF00400 0.560
TRG_Pf-PMV_PEXEL_1 106 110 PF00026 0.474
TRG_Pf-PMV_PEXEL_1 262 266 PF00026 0.521

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I0N8 Leptomonas seymouri 43% 100%
A4H3X3 Leishmania braziliensis 63% 100%
A4HS48 Leishmania infantum 100% 100%
E9AK35 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
O97202 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS