LeishMANIAdb
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C-type lectin domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
C-type lectin domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WNQ2_LEIDO
TriTrypDb:
LdBPK_040410.1 * , LdCL_040009600 , LDHU3_04.0540
Length:
672

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A0A3S7WNQ2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNQ2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 122 126 PF00656 0.375
CLV_C14_Caspase3-7 371 375 PF00656 0.523
CLV_PCSK_KEX2_1 348 350 PF00082 0.340
CLV_PCSK_PC1ET2_1 348 350 PF00082 0.340
CLV_PCSK_SKI1_1 159 163 PF00082 0.473
CLV_PCSK_SKI1_1 349 353 PF00082 0.340
CLV_PCSK_SKI1_1 470 474 PF00082 0.259
DEG_APCC_DBOX_1 209 217 PF00400 0.399
DEG_SPOP_SBC_1 311 315 PF00917 0.617
DEG_SPOP_SBC_1 598 602 PF00917 0.634
DOC_CKS1_1 103 108 PF01111 0.316
DOC_CKS1_1 350 355 PF01111 0.551
DOC_CKS1_1 438 443 PF01111 0.546
DOC_CKS1_1 591 596 PF01111 0.620
DOC_CYCLIN_RxL_1 156 164 PF00134 0.273
DOC_MAPK_DCC_7 37 45 PF00069 0.400
DOC_MAPK_MEF2A_6 37 45 PF00069 0.400
DOC_PP4_FxxP_1 555 558 PF00568 0.568
DOC_USP7_MATH_1 108 112 PF00917 0.294
DOC_USP7_MATH_1 14 18 PF00917 0.599
DOC_USP7_MATH_1 148 152 PF00917 0.277
DOC_USP7_MATH_1 191 195 PF00917 0.334
DOC_USP7_MATH_1 250 254 PF00917 0.399
DOC_USP7_MATH_1 27 31 PF00917 0.598
DOC_USP7_MATH_1 309 313 PF00917 0.612
DOC_USP7_MATH_1 386 390 PF00917 0.492
DOC_USP7_MATH_1 411 415 PF00917 0.483
DOC_USP7_MATH_1 506 510 PF00917 0.524
DOC_USP7_MATH_1 551 555 PF00917 0.574
DOC_USP7_MATH_1 596 600 PF00917 0.634
DOC_USP7_MATH_1 606 610 PF00917 0.600
DOC_USP7_MATH_1 630 634 PF00917 0.580
DOC_WW_Pin1_4 102 107 PF00397 0.309
DOC_WW_Pin1_4 131 136 PF00397 0.363
DOC_WW_Pin1_4 140 145 PF00397 0.328
DOC_WW_Pin1_4 215 220 PF00397 0.399
DOC_WW_Pin1_4 25 30 PF00397 0.596
DOC_WW_Pin1_4 349 354 PF00397 0.542
DOC_WW_Pin1_4 437 442 PF00397 0.538
DOC_WW_Pin1_4 504 509 PF00397 0.542
DOC_WW_Pin1_4 536 541 PF00397 0.465
DOC_WW_Pin1_4 554 559 PF00397 0.564
DOC_WW_Pin1_4 590 595 PF00397 0.614
DOC_WW_Pin1_4 600 605 PF00397 0.631
DOC_WW_Pin1_4 78 83 PF00397 0.295
DOC_WW_Pin1_4 9 14 PF00397 0.591
LIG_14-3-3_CanoR_1 37 41 PF00244 0.400
LIG_14-3-3_CanoR_1 571 575 PF00244 0.482
LIG_BIR_II_1 1 5 PF00653 0.599
LIG_BRCT_BRCA1_1 551 555 PF00533 0.574
LIG_eIF4E_1 492 498 PF01652 0.479
LIG_FHA_1 128 134 PF00498 0.374
LIG_FHA_1 239 245 PF00498 0.399
LIG_FHA_1 469 475 PF00498 0.468
LIG_FHA_2 207 213 PF00498 0.402
LIG_FHA_2 240 246 PF00498 0.398
LIG_FHA_2 542 548 PF00498 0.547
LIG_FHA_2 632 638 PF00498 0.590
LIG_FHA_2 644 650 PF00498 0.567
LIG_GBD_Chelix_1 427 435 PF00786 0.270
LIG_LIR_Apic_2 140 144 PF02991 0.334
LIG_LIR_Apic_2 552 558 PF02991 0.570
LIG_LIR_Apic_2 78 83 PF02991 0.295
LIG_LIR_Gen_1 17 26 PF02991 0.608
LIG_LIR_Gen_1 256 266 PF02991 0.312
LIG_LIR_Gen_1 280 290 PF02991 0.199
LIG_LIR_Gen_1 302 311 PF02991 0.578
LIG_LIR_Gen_1 361 370 PF02991 0.504
LIG_LIR_Gen_1 614 621 PF02991 0.542
LIG_LIR_Nem_3 12 18 PF02991 0.596
LIG_LIR_Nem_3 256 262 PF02991 0.321
LIG_LIR_Nem_3 280 286 PF02991 0.270
LIG_LIR_Nem_3 302 306 PF02991 0.551
LIG_LIR_Nem_3 361 366 PF02991 0.500
LIG_LIR_Nem_3 532 536 PF02991 0.506
LIG_LIR_Nem_3 585 590 PF02991 0.564
LIG_LIR_Nem_3 614 619 PF02991 0.536
LIG_LIR_Nem_3 624 629 PF02991 0.542
LIG_Pex14_2 158 162 PF04695 0.264
LIG_Pex14_2 295 299 PF04695 0.199
LIG_PTB_Apo_2 620 627 PF02174 0.544
LIG_PTB_Phospho_1 620 626 PF10480 0.544
LIG_REV1ctd_RIR_1 155 163 PF16727 0.265
LIG_SH2_CRK 141 145 PF00017 0.319
LIG_SH2_CRK 184 188 PF00017 0.301
LIG_SH2_CRK 533 537 PF00017 0.489
LIG_SH2_CRK 80 84 PF00017 0.313
LIG_SH2_GRB2like 259 262 PF00017 0.281
LIG_SH2_GRB2like 521 524 PF00017 0.482
LIG_SH2_GRB2like 580 583 PF00017 0.470
LIG_SH2_NCK_1 190 194 PF00017 0.324
LIG_SH2_NCK_1 503 507 PF00017 0.542
LIG_SH2_SRC 190 193 PF00017 0.315
LIG_SH2_STAP1 138 142 PF00017 0.344
LIG_SH2_STAP1 259 263 PF00017 0.277
LIG_SH2_STAP1 492 496 PF00017 0.481
LIG_SH2_STAT3 492 495 PF00017 0.474
LIG_SH2_STAT5 259 262 PF00017 0.281
LIG_SH2_STAT5 405 408 PF00017 0.488
LIG_SH2_STAT5 496 499 PF00017 0.491
LIG_SH2_STAT5 580 583 PF00017 0.470
LIG_SH3_3 23 29 PF00018 0.599
LIG_SH3_3 302 308 PF00018 0.565
LIG_SH3_3 347 353 PF00018 0.543
LIG_SH3_3 435 441 PF00018 0.517
LIG_SH3_3 505 511 PF00018 0.525
LIG_SH3_3 52 58 PF00018 0.199
LIG_SH3_3 537 543 PF00018 0.482
LIG_SH3_3 585 591 PF00018 0.570
LIG_SUMO_SIM_anti_2 171 179 PF11976 0.301
LIG_TRAF2_1 420 423 PF00917 0.485
LIG_TRAF2_1 646 649 PF00917 0.561
LIG_TYR_ITIM 531 536 PF00017 0.508
LIG_WRC_WIRS_1 15 20 PF05994 0.606
MOD_CK1_1 111 117 PF00069 0.300
MOD_CK1_1 118 124 PF00069 0.349
MOD_CK1_1 160 166 PF00069 0.282
MOD_CK1_1 17 23 PF00069 0.611
MOD_CK1_1 253 259 PF00069 0.374
MOD_CK1_1 28 34 PF00069 0.601
MOD_CK1_1 288 294 PF00069 0.199
MOD_CK1_1 312 318 PF00069 0.623
MOD_CK1_1 323 329 PF00069 0.631
MOD_CK1_1 361 367 PF00069 0.499
MOD_CK1_1 369 375 PF00069 0.518
MOD_CK1_1 414 420 PF00069 0.465
MOD_CK1_1 458 464 PF00069 0.566
MOD_CK1_1 468 474 PF00069 0.485
MOD_CK1_1 507 513 PF00069 0.504
MOD_CK1_1 554 560 PF00069 0.558
MOD_CK1_1 599 605 PF00069 0.630
MOD_CK1_1 614 620 PF00069 0.539
MOD_CK1_1 631 637 PF00069 0.588
MOD_CK1_1 640 646 PF00069 0.586
MOD_CK1_1 78 84 PF00069 0.306
MOD_CK2_1 107 113 PF00069 0.293
MOD_CK2_1 148 154 PF00069 0.276
MOD_CK2_1 206 212 PF00069 0.406
MOD_CK2_1 239 245 PF00069 0.399
MOD_CK2_1 326 332 PF00069 0.634
MOD_CK2_1 417 423 PF00069 0.478
MOD_CK2_1 496 502 PF00069 0.511
MOD_CK2_1 604 610 PF00069 0.606
MOD_CK2_1 631 637 PF00069 0.588
MOD_CK2_1 643 649 PF00069 0.570
MOD_CK2_1 88 94 PF00069 0.356
MOD_DYRK1A_RPxSP_1 349 353 PF00069 0.540
MOD_GlcNHglycan 110 113 PF01048 0.491
MOD_GlcNHglycan 121 124 PF01048 0.567
MOD_GlcNHglycan 150 153 PF01048 0.488
MOD_GlcNHglycan 247 250 PF01048 0.595
MOD_GlcNHglycan 251 255 PF01048 0.600
MOD_GlcNHglycan 271 274 PF01048 0.508
MOD_GlcNHglycan 279 282 PF01048 0.484
MOD_GlcNHglycan 287 290 PF01048 0.199
MOD_GlcNHglycan 314 317 PF01048 0.425
MOD_GlcNHglycan 323 326 PF01048 0.429
MOD_GlcNHglycan 336 339 PF01048 0.427
MOD_GlcNHglycan 360 363 PF01048 0.313
MOD_GlcNHglycan 428 431 PF01048 0.273
MOD_GlcNHglycan 432 435 PF01048 0.276
MOD_GlcNHglycan 462 465 PF01048 0.355
MOD_GlcNHglycan 467 470 PF01048 0.338
MOD_GlcNHglycan 483 486 PF01048 0.338
MOD_GlcNHglycan 498 501 PF01048 0.317
MOD_GlcNHglycan 559 562 PF01048 0.323
MOD_GlcNHglycan 613 616 PF01048 0.339
MOD_GlcNHglycan 630 633 PF01048 0.377
MOD_GlcNHglycan 639 642 PF01048 0.400
MOD_GlcNHglycan 90 93 PF01048 0.557
MOD_GSK3_1 107 114 PF00069 0.297
MOD_GSK3_1 115 122 PF00069 0.324
MOD_GSK3_1 127 134 PF00069 0.376
MOD_GSK3_1 217 224 PF00069 0.404
MOD_GSK3_1 25 32 PF00069 0.599
MOD_GSK3_1 253 260 PF00069 0.364
MOD_GSK3_1 277 284 PF00069 0.271
MOD_GSK3_1 307 314 PF00069 0.610
MOD_GSK3_1 319 326 PF00069 0.630
MOD_GSK3_1 328 335 PF00069 0.635
MOD_GSK3_1 366 373 PF00069 0.500
MOD_GSK3_1 426 433 PF00069 0.464
MOD_GSK3_1 440 447 PF00069 0.568
MOD_GSK3_1 550 557 PF00069 0.573
MOD_GSK3_1 582 589 PF00069 0.533
MOD_GSK3_1 596 603 PF00069 0.634
MOD_N-GLC_1 222 227 PF02516 0.611
MOD_N-GLC_1 386 391 PF02516 0.291
MOD_N-GLC_1 549 554 PF02516 0.376
MOD_N-GLC_2 3 5 PF02516 0.399
MOD_N-GLC_2 623 625 PF02516 0.336
MOD_NEK2_1 115 120 PF00069 0.314
MOD_NEK2_1 157 162 PF00069 0.262
MOD_NEK2_1 222 227 PF00069 0.411
MOD_NEK2_1 238 243 PF00069 0.400
MOD_NEK2_1 277 282 PF00069 0.278
MOD_NEK2_1 285 290 PF00069 0.199
MOD_NEK2_1 474 479 PF00069 0.470
MOD_NEK2_1 487 492 PF00069 0.475
MOD_NEK2_1 519 524 PF00069 0.498
MOD_NEK2_1 576 581 PF00069 0.444
MOD_NEK2_1 619 624 PF00069 0.546
MOD_NEK2_2 75 80 PF00069 0.291
MOD_PIKK_1 417 423 PF00454 0.478
MOD_PIKK_1 570 576 PF00454 0.477
MOD_PKA_2 269 275 PF00069 0.311
MOD_PKA_2 277 283 PF00069 0.272
MOD_PKA_2 36 42 PF00069 0.400
MOD_PKA_2 479 485 PF00069 0.527
MOD_PKA_2 570 576 PF00069 0.477
MOD_Plk_1 301 307 PF00069 0.546
MOD_Plk_4 115 121 PF00069 0.320
MOD_Plk_4 217 223 PF00069 0.402
MOD_Plk_4 414 420 PF00069 0.465
MOD_Plk_4 455 461 PF00069 0.582
MOD_Plk_4 474 480 PF00069 0.478
MOD_Plk_4 487 493 PF00069 0.473
MOD_Plk_4 576 582 PF00069 0.447
MOD_ProDKin_1 102 108 PF00069 0.309
MOD_ProDKin_1 131 137 PF00069 0.364
MOD_ProDKin_1 140 146 PF00069 0.320
MOD_ProDKin_1 215 221 PF00069 0.400
MOD_ProDKin_1 25 31 PF00069 0.598
MOD_ProDKin_1 349 355 PF00069 0.546
MOD_ProDKin_1 437 443 PF00069 0.542
MOD_ProDKin_1 504 510 PF00069 0.535
MOD_ProDKin_1 536 542 PF00069 0.474
MOD_ProDKin_1 554 560 PF00069 0.558
MOD_ProDKin_1 590 596 PF00069 0.617
MOD_ProDKin_1 600 606 PF00069 0.630
MOD_ProDKin_1 78 84 PF00069 0.306
MOD_ProDKin_1 9 15 PF00069 0.593
TRG_ENDOCYTIC_2 184 187 PF00928 0.300
TRG_ENDOCYTIC_2 190 193 PF00928 0.315
TRG_ENDOCYTIC_2 259 262 PF00928 0.281
TRG_ENDOCYTIC_2 382 385 PF00928 0.443
TRG_ENDOCYTIC_2 533 536 PF00928 0.495
TRG_ENDOCYTIC_2 626 629 PF00928 0.548
TRG_Pf-PMV_PEXEL_1 159 164 PF00026 0.481

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS