LeishMANIAdb
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40S ribosomal protein S7

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
40S ribosomal protein S7
Gene product:
ribosomal protein S7, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WNJ7_LEIDO
TriTrypDb:
LdBPK_010440.1 , LdCL_010009300 , LdCL_010009400 , LDHU3_01.0460 , LDHU3_01.0470
Length:
200

Annotations

Annotations by Jardim et al.

Ribosomal Protein, ribosomal S7

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) yes yes: 4
Forrest at al. (procyclic) yes yes: 4
Silverman et al. no yes: 0
Pissara et al. yes yes: 12
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 10
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 13
GO:0032991 protein-containing complex 1 14
GO:0043226 organelle 2 13
GO:0043228 non-membrane-bounded organelle 3 13
GO:0043229 intracellular organelle 3 13
GO:0043232 intracellular non-membrane-bounded organelle 4 13
GO:0110165 cellular anatomical entity 1 14
GO:1990904 ribonucleoprotein complex 2 14
GO:0005737 cytoplasm 2 1
GO:0015935 small ribosomal subunit 4 1
GO:0022627 cytosolic small ribosomal subunit 5 1
GO:0030684 preribosome 3 1
GO:0032040 small-subunit processome 4 1
GO:0044391 ribosomal subunit 3 1

Expansion

Sequence features

A0A3S7WNJ7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WNJ7

PDB structure(s): 6az1_I

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 14
GO:0006518 peptide metabolic process 4 14
GO:0006807 nitrogen compound metabolic process 2 14
GO:0008152 metabolic process 1 14
GO:0009058 biosynthetic process 2 14
GO:0009059 macromolecule biosynthetic process 4 14
GO:0009987 cellular process 1 14
GO:0019538 protein metabolic process 3 14
GO:0034641 cellular nitrogen compound metabolic process 3 14
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 14
GO:0043043 peptide biosynthetic process 5 14
GO:0043170 macromolecule metabolic process 3 14
GO:0043603 amide metabolic process 3 14
GO:0043604 amide biosynthetic process 4 14
GO:0044237 cellular metabolic process 2 14
GO:0044238 primary metabolic process 2 14
GO:0044249 cellular biosynthetic process 3 14
GO:0044260 obsolete cellular macromolecule metabolic process 3 14
GO:0044271 cellular nitrogen compound biosynthetic process 4 14
GO:0071704 organic substance metabolic process 2 14
GO:1901564 organonitrogen compound metabolic process 3 14
GO:1901566 organonitrogen compound biosynthetic process 4 14
GO:1901576 organic substance biosynthetic process 3 14
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006364 rRNA processing 8 1
GO:0006396 RNA processing 6 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0016070 RNA metabolic process 5 1
GO:0016072 rRNA metabolic process 7 1
GO:0022613 ribonucleoprotein complex biogenesis 4 1
GO:0034470 ncRNA processing 7 1
GO:0034660 ncRNA metabolic process 6 1
GO:0042274 ribosomal small subunit biogenesis 5 1
GO:0044085 cellular component biogenesis 3 1
GO:0046483 heterocycle metabolic process 3 1
GO:0071840 cellular component organization or biogenesis 2 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 14
GO:0005198 structural molecule activity 1 14

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 141 143 PF00675 0.308
CLV_NRD_NRD_1 161 163 PF00675 0.311
CLV_NRD_NRD_1 182 184 PF00675 0.414
CLV_NRD_NRD_1 5 7 PF00675 0.449
CLV_NRD_NRD_1 74 76 PF00675 0.349
CLV_NRD_NRD_1 8 10 PF00675 0.318
CLV_NRD_NRD_1 99 101 PF00675 0.284
CLV_PCSK_KEX2_1 104 106 PF00082 0.310
CLV_PCSK_KEX2_1 12 14 PF00082 0.318
CLV_PCSK_KEX2_1 141 143 PF00082 0.308
CLV_PCSK_KEX2_1 163 165 PF00082 0.315
CLV_PCSK_KEX2_1 182 184 PF00082 0.414
CLV_PCSK_KEX2_1 87 89 PF00082 0.317
CLV_PCSK_PC1ET2_1 104 106 PF00082 0.308
CLV_PCSK_PC1ET2_1 12 14 PF00082 0.318
CLV_PCSK_PC1ET2_1 163 165 PF00082 0.327
CLV_PCSK_PC1ET2_1 87 89 PF00082 0.308
CLV_PCSK_PC7_1 100 106 PF00082 0.308
CLV_PCSK_SKI1_1 100 104 PF00082 0.320
CLV_PCSK_SKI1_1 151 155 PF00082 0.320
CLV_PCSK_SKI1_1 177 181 PF00082 0.315
CLV_PCSK_SKI1_1 25 29 PF00082 0.318
CLV_PCSK_SKI1_1 50 54 PF00082 0.350
CLV_PCSK_SKI1_1 59 63 PF00082 0.341
CLV_PCSK_SKI1_1 79 83 PF00082 0.290
CLV_PCSK_SKI1_1 9 13 PF00082 0.320
CLV_Separin_Metazoa 40 44 PF03568 0.615
DEG_Nend_UBRbox_3 1 3 PF02207 0.638
DOC_CYCLIN_RxL_1 22 32 PF00134 0.529
DOC_MAPK_gen_1 53 63 PF00069 0.525
DOC_MAPK_MEF2A_6 56 65 PF00069 0.582
DOC_PP1_RVXF_1 180 187 PF00149 0.498
DOC_SPAK_OSR1_1 43 47 PF12202 0.518
DOC_USP7_MATH_1 80 84 PF00917 0.570
LIG_14-3-3_CanoR_1 117 125 PF00244 0.510
LIG_14-3-3_CanoR_1 144 153 PF00244 0.527
LIG_14-3-3_CanoR_1 182 187 PF00244 0.530
LIG_14-3-3_CanoR_1 56 62 PF00244 0.544
LIG_APCC_ABBA_1 153 158 PF00400 0.527
LIG_BRCT_BRCA1_1 184 188 PF00533 0.558
LIG_Clathr_ClatBox_1 27 31 PF01394 0.529
LIG_eIF4E_1 66 72 PF01652 0.518
LIG_FHA_1 58 64 PF00498 0.543
LIG_FHA_1 80 86 PF00498 0.508
LIG_FHA_2 46 52 PF00498 0.541
LIG_LIR_Gen_1 122 133 PF02991 0.599
LIG_LIR_LC3C_4 60 64 PF02991 0.519
LIG_LIR_Nem_3 122 128 PF02991 0.599
LIG_Pex14_2 186 190 PF04695 0.515
LIG_SH2_CRK 176 180 PF00017 0.515
LIG_SH2_STAT3 110 113 PF00017 0.508
LIG_SH2_STAT5 174 177 PF00017 0.614
LIG_SH2_STAT5 4 7 PF00017 0.548
LIG_SH2_STAT5 92 95 PF00017 0.513
LIG_SH3_3 49 55 PF00018 0.556
LIG_SH3_3 61 67 PF00018 0.491
LIG_SUMO_SIM_anti_2 60 65 PF11976 0.530
LIG_UBA3_1 27 35 PF00899 0.518
MOD_CK1_1 118 124 PF00069 0.508
MOD_CK1_1 33 39 PF00069 0.581
MOD_CK1_1 57 63 PF00069 0.615
MOD_CK2_1 14 20 PF00069 0.518
MOD_CK2_1 45 51 PF00069 0.581
MOD_CK2_1 80 86 PF00069 0.617
MOD_Cter_Amidation 139 142 PF01082 0.308
MOD_GSK3_1 100 107 PF00069 0.548
MOD_GSK3_1 115 122 PF00069 0.592
MOD_GSK3_1 29 36 PF00069 0.569
MOD_NEK2_1 19 24 PF00069 0.554
MOD_NEK2_1 30 35 PF00069 0.480
MOD_PKA_1 100 106 PF00069 0.504
MOD_PKA_1 182 188 PF00069 0.614
MOD_PKA_2 104 110 PF00069 0.525
MOD_PKA_2 182 188 PF00069 0.614
MOD_PKB_1 142 150 PF00069 0.515
MOD_PKB_1 162 170 PF00069 0.524
MOD_Plk_1 19 25 PF00069 0.543
MOD_Plk_4 57 63 PF00069 0.530
MOD_SUMO_rev_2 158 165 PF00179 0.515
TRG_ENDOCYTIC_2 176 179 PF00928 0.515
TRG_ENDOCYTIC_2 92 95 PF00928 0.513
TRG_ER_diArg_1 141 143 PF00400 0.506
TRG_ER_diArg_1 162 165 PF00400 0.515
TRG_ER_diArg_1 182 184 PF00400 0.601
TRG_NLS_MonoExtC_3 11 16 PF00514 0.518
TRG_NLS_MonoExtC_3 5 10 PF00514 0.463
TRG_NLS_MonoExtN_4 3 10 PF00514 0.464
TRG_Pf-PMV_PEXEL_1 25 29 PF00026 0.329
TRG_Pf-PMV_PEXEL_1 79 84 PF00026 0.318

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PA77 Leptomonas seymouri 88% 100%
A0A0S4JIP7 Bodo saltans 72% 100%
A0A1X0P313 Trypanosomatidae 80% 99%
A0A3R7KMI4 Trypanosoma rangeli 83% 100%
A0A3R7KV77 Trypanosoma rangeli 77% 100%
A0A3R7M7D1 Trypanosoma rangeli 78% 99%
A4H367 Leishmania braziliensis 92% 100%
A4H368 Leishmania braziliensis 92% 100%
A4HRG4 Leishmania infantum 100% 100%
A6H769 Bos taurus 37% 100%
C9ZXI9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 78% 99%
E9AC32 Leishmania major 98% 100%
E9AJC9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
O43105 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 40% 99%
P02362 Xenopus laevis 38% 100%
P26786 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 38% 100%
P33514 Anopheles gambiae 36% 100%
P48155 Manduca sexta 36% 100%
P48164 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 38% 100%
P50894 Takifugu rubripes 36% 100%
P62081 Homo sapiens 37% 100%
P62082 Mus musculus 37% 100%
P62083 Rattus norvegicus 37% 100%
P62084 Danio rerio 38% 100%
P62085 Drosophila yakuba 38% 100%
Q10101 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 39% 100%
Q23312 Caenorhabditis elegans 35% 100%
Q54I41 Dictyostelium discoideum 41% 100%
Q5AJ93 Candida albicans (strain SC5314 / ATCC MYA-2876) 39% 100%
Q5RT64 Felis catus 37% 100%
Q8LD03 Arabidopsis thaliana 37% 100%
Q8LJU5 Oryza sativa subsp. japonica 35% 100%
Q90YR7 Ictalurus punctatus 38% 100%
Q949H0 Hordeum vulgare 36% 100%
Q962S0 Spodoptera frugiperda 36% 100%
Q9C514 Arabidopsis thaliana 40% 100%
Q9M885 Arabidopsis thaliana 37% 100%
Q9NB21 Culex quinquefasciatus 35% 100%
Q9VA91 Drosophila melanogaster 38% 100%
Q9XET4 Secale cereale 34% 100%
Q9XH45 Brassica oleracea 36% 100%
Q9ZNS1 Avicennia marina 38% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS