| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 9 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 |
| NetGPI | no | yes: 0, no: 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005730 | nucleolus | 5 | 1 |
| GO:0005732 | sno(s)RNA-containing ribonucleoprotein complex | 3 | 1 |
| GO:0030684 | preribosome | 3 | 1 |
| GO:0031428 | box C/D RNP complex | 4 | 1 |
| GO:0032040 | small-subunit processome | 4 | 1 |
| GO:0032991 | protein-containing complex | 1 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043228 | non-membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 4 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
| GO:1990904 | ribonucleoprotein complex | 2 | 1 |
Related structures:
AlphaFold database: A0A3S5H830
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006139 | nucleobase-containing compound metabolic process | 3 | 13 |
| GO:0006364 | rRNA processing | 8 | 13 |
| GO:0006396 | RNA processing | 6 | 13 |
| GO:0006725 | cellular aromatic compound metabolic process | 3 | 13 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 13 |
| GO:0008152 | metabolic process | 1 | 13 |
| GO:0009987 | cellular process | 1 | 13 |
| GO:0016070 | RNA metabolic process | 5 | 13 |
| GO:0016072 | rRNA metabolic process | 7 | 13 |
| GO:0032259 | methylation | 2 | 13 |
| GO:0034470 | ncRNA processing | 7 | 13 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 13 |
| GO:0034660 | ncRNA metabolic process | 6 | 13 |
| GO:0043170 | macromolecule metabolic process | 3 | 13 |
| GO:0044237 | cellular metabolic process | 2 | 13 |
| GO:0044238 | primary metabolic process | 2 | 13 |
| GO:0046483 | heterocycle metabolic process | 3 | 13 |
| GO:0071704 | organic substance metabolic process | 2 | 13 |
| GO:0090304 | nucleic acid metabolic process | 4 | 13 |
| GO:1901360 | organic cyclic compound metabolic process | 3 | 13 |
| GO:0000154 | rRNA modification | 6 | 1 |
| GO:0000494 | box C/D RNA 3'-end processing | 10 | 1 |
| GO:0001510 | RNA methylation | 4 | 1 |
| GO:0006479 | protein methylation | 4 | 1 |
| GO:0008213 | protein alkylation | 5 | 1 |
| GO:0009451 | RNA modification | 5 | 1 |
| GO:0016074 | sno(s)RNA metabolic process | 7 | 1 |
| GO:0016570 | histone modification | 5 | 1 |
| GO:0016571 | histone methylation | 5 | 1 |
| GO:0018364 | peptidyl-glutamine methylation | 5 | 1 |
| GO:0019538 | protein metabolic process | 3 | 1 |
| GO:0031123 | RNA 3'-end processing | 7 | 1 |
| GO:0031126 | sno(s)RNA 3'-end processing | 9 | 1 |
| GO:0031167 | rRNA methylation | 5 | 1 |
| GO:0033967 | box C/D RNA metabolic process | 8 | 1 |
| GO:0034963 | box C/D RNA processing | 9 | 1 |
| GO:0036211 | protein modification process | 4 | 1 |
| GO:0043144 | sno(s)RNA processing | 8 | 1 |
| GO:0043412 | macromolecule modification | 4 | 1 |
| GO:0043414 | macromolecule methylation | 3 | 1 |
| GO:0043628 | regulatory ncRNA 3'-end processing | 8 | 1 |
| GO:0044260 | obsolete cellular macromolecule metabolic process | 3 | 1 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 1 |
| GO:1990258 | histone glutamine methylation | 6 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 13 |
| GO:0003723 | RNA binding | 4 | 13 |
| GO:0003824 | catalytic activity | 1 | 13 |
| GO:0005488 | binding | 1 | 13 |
| GO:0008168 | methyltransferase activity | 4 | 13 |
| GO:0016740 | transferase activity | 2 | 13 |
| GO:0016741 | transferase activity, transferring one-carbon groups | 3 | 13 |
| GO:0097159 | organic cyclic compound binding | 2 | 13 |
| GO:1901363 | heterocyclic compound binding | 2 | 13 |
| GO:0008170 | N-methyltransferase activity | 5 | 1 |
| GO:0008173 | RNA methyltransferase activity | 4 | 1 |
| GO:0008276 | protein methyltransferase activity | 3 | 1 |
| GO:0008649 | rRNA methyltransferase activity | 5 | 1 |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | 5 | 1 |
| GO:0036009 | protein-glutamine N-methyltransferase activity | 4 | 1 |
| GO:0042054 | histone methyltransferase activity | 4 | 1 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 1 |
| GO:0140098 | catalytic activity, acting on RNA | 3 | 1 |
| GO:0140102 | catalytic activity, acting on a rRNA | 4 | 1 |
| GO:0140640 | catalytic activity, acting on a nucleic acid | 2 | 1 |
| GO:1990259 | histone H2AQ104 methyltransferase activity | 5 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 190 | 192 | PF00675 | 0.281 |
| CLV_PCSK_KEX2_1 | 102 | 104 | PF00082 | 0.272 |
| CLV_PCSK_KEX2_1 | 189 | 191 | PF00082 | 0.281 |
| CLV_PCSK_PC1ET2_1 | 102 | 104 | PF00082 | 0.281 |
| CLV_PCSK_PC1ET2_1 | 189 | 191 | PF00082 | 0.281 |
| CLV_PCSK_SKI1_1 | 298 | 302 | PF00082 | 0.445 |
| DEG_Nend_UBRbox_1 | 1 | 4 | PF02207 | 0.443 |
| DOC_CYCLIN_yCln2_LP_2 | 257 | 263 | PF00134 | 0.294 |
| DOC_MAPK_gen_1 | 189 | 197 | PF00069 | 0.281 |
| DOC_MAPK_gen_1 | 274 | 283 | PF00069 | 0.377 |
| DOC_MAPK_MEF2A_6 | 206 | 213 | PF00069 | 0.310 |
| DOC_MAPK_MEF2A_6 | 288 | 296 | PF00069 | 0.294 |
| DOC_PP2B_LxvP_1 | 257 | 260 | PF13499 | 0.294 |
| DOC_PP2B_PxIxI_1 | 93 | 99 | PF00149 | 0.377 |
| DOC_USP7_MATH_1 | 123 | 127 | PF00917 | 0.310 |
| DOC_USP7_MATH_1 | 134 | 138 | PF00917 | 0.281 |
| DOC_USP7_MATH_2 | 277 | 283 | PF00917 | 0.294 |
| DOC_USP7_UBL2_3 | 272 | 276 | PF12436 | 0.294 |
| LIG_APCC_ABBA_1 | 96 | 101 | PF00400 | 0.281 |
| LIG_FHA_1 | 82 | 88 | PF00498 | 0.419 |
| LIG_IBAR_NPY_1 | 122 | 124 | PF08397 | 0.281 |
| LIG_LIR_Gen_1 | 215 | 224 | PF02991 | 0.281 |
| LIG_LIR_Nem_3 | 130 | 136 | PF02991 | 0.377 |
| LIG_LIR_Nem_3 | 215 | 221 | PF02991 | 0.281 |
| LIG_SH2_CRK | 133 | 137 | PF00017 | 0.294 |
| LIG_SH2_CRK | 207 | 211 | PF00017 | 0.281 |
| LIG_SH2_CRK | 297 | 301 | PF00017 | 0.413 |
| LIG_SH2_SRC | 244 | 247 | PF00017 | 0.294 |
| LIG_SH2_STAP1 | 172 | 176 | PF00017 | 0.281 |
| LIG_SH2_STAT5 | 149 | 152 | PF00017 | 0.281 |
| LIG_SH2_STAT5 | 244 | 247 | PF00017 | 0.294 |
| LIG_SH3_3 | 218 | 224 | PF00018 | 0.281 |
| LIG_SH3_3 | 293 | 299 | PF00018 | 0.425 |
| LIG_SH3_4 | 276 | 283 | PF00018 | 0.294 |
| LIG_SUMO_SIM_par_1 | 258 | 266 | PF11976 | 0.349 |
| MOD_CK1_1 | 159 | 165 | PF00069 | 0.302 |
| MOD_CK1_1 | 86 | 92 | PF00069 | 0.294 |
| MOD_CK2_1 | 252 | 258 | PF00069 | 0.272 |
| MOD_GlcNHglycan | 129 | 132 | PF01048 | 0.403 |
| MOD_GSK3_1 | 123 | 130 | PF00069 | 0.375 |
| MOD_GSK3_1 | 77 | 84 | PF00069 | 0.389 |
| MOD_NEK2_1 | 106 | 111 | PF00069 | 0.328 |
| MOD_NEK2_2 | 135 | 140 | PF00069 | 0.294 |
| MOD_NEK2_2 | 244 | 249 | PF00069 | 0.281 |
| MOD_NEK2_2 | 94 | 99 | PF00069 | 0.281 |
| MOD_PIKK_1 | 106 | 112 | PF00454 | 0.310 |
| MOD_Plk_1 | 253 | 259 | PF00069 | 0.294 |
| MOD_Plk_2-3 | 279 | 285 | PF00069 | 0.281 |
| TRG_ENDOCYTIC_2 | 133 | 136 | PF00928 | 0.281 |
| TRG_ENDOCYTIC_2 | 207 | 210 | PF00928 | 0.281 |
| TRG_ENDOCYTIC_2 | 297 | 300 | PF00928 | 0.397 |
| TRG_ER_diArg_1 | 190 | 192 | PF00400 | 0.270 |
| TRG_ER_diLys_1 | 301 | 305 | PF00400 | 0.532 |
| TRG_NES_CRM1_1 | 273 | 287 | PF08389 | 0.377 |
| TRG_NLS_MonoExtN_4 | 298 | 305 | PF00514 | 0.529 |
| TRG_Pf-PMV_PEXEL_1 | 182 | 186 | PF00026 | 0.281 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P7A3 | Leptomonas seymouri | 97% | 100% |
| A0A0N1PA75 | Leptomonas seymouri | 67% | 100% |
| A0A0S4IYN2 | Bodo saltans | 64% | 99% |
| A0A0S4J8H3 | Bodo saltans | 88% | 100% |
| A0A1X0NKM9 | Trypanosomatidae | 93% | 100% |
| A0A1X0P6R0 | Trypanosomatidae | 68% | 99% |
| A0A3Q8ID71 | Leishmania donovani | 68% | 100% |
| A0A422NCX2 | Trypanosoma rangeli | 58% | 100% |
| A0A422NM05 | Trypanosoma rangeli | 85% | 100% |
| A1RRJ7 | Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) | 46% | 100% |
| A3DNY7 | Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1) | 45% | 100% |
| A3MV65 | Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) | 45% | 100% |
| A4FYN1 | Methanococcus maripaludis (strain C5 / ATCC BAA-1333) | 41% | 100% |
| A4H9W7 | Leishmania braziliensis | 68% | 70% |
| A4HPH3 | Leishmania braziliensis | 99% | 100% |
| A4ID95 | Leishmania infantum | 100% | 100% |
| A4WKL2 | Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6) | 46% | 100% |
| A6NHQ2 | Homo sapiens | 67% | 91% |
| A6UV22 | Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3) | 43% | 100% |
| A6VJQ1 | Methanococcus maripaludis (strain C7 / ATCC BAA-1331) | 40% | 100% |
| A9A6C8 | Methanococcus maripaludis (strain C6 / ATCC BAA-1332) | 41% | 100% |
| B1YAJ6 | Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta) | 46% | 100% |
| B6YXH6 | Thermococcus onnurineus (strain NA1) | 50% | 100% |
| C3MPR8 | Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) | 43% | 100% |
| C3MYR2 | Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) | 43% | 100% |
| C3N5E4 | Sulfolobus islandicus (strain M.16.27) | 43% | 100% |
| C3NDZ8 | Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) | 43% | 100% |
| C3NHQ5 | Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) | 43% | 100% |
| C4KH10 | Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) | 43% | 100% |
| C5A403 | Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) | 49% | 100% |
| C6A2L3 | Thermococcus sibiricus (strain DSM 12597 / MM 739) | 48% | 100% |
| D0A0B7 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 72% | 100% |
| D0A0D0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 69% | 100% |
| D0A3I3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 88% | 100% |
| E9AGR2 | Leishmania infantum | 68% | 100% |
| E9ARW1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 68% | 100% |
| E9AT85 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 100% | 100% |
| O27283 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 42% | 100% |
| O57811 | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) | 47% | 100% |
| P0CW09 | Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) | 44% | 100% |
| P15646 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 62% | 93% |
| P22087 | Homo sapiens | 66% | 95% |
| P22232 | Xenopus laevis | 65% | 94% |
| P22509 | Rattus norvegicus | 66% | 93% |
| P35549 | Leishmania major | 99% | 100% |
| P35550 | Mus musculus | 66% | 93% |
| P35551 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 62% | 100% |
| P35552 | Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) | 42% | 100% |
| P35553 | Methanococcus voltae | 43% | 100% |
| P58032 | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) | 43% | 100% |
| Q22053 | Caenorhabditis elegans | 69% | 87% |
| Q24957 | Giardia intestinalis | 56% | 93% |
| Q27200 | Tetrahymena thermophila | 62% | 100% |
| Q46EB1 | Methanosarcina barkeri (strain Fusaro / DSM 804) | 46% | 100% |
| Q4Q1B2 | Leishmania major | 100% | 100% |
| Q4QDL1 | Leishmania major | 68% | 100% |
| Q55CW0 | Dictyostelium discoideum | 61% | 91% |
| Q58108 | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | 42% | 100% |
| Q5JFN1 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 49% | 100% |
| Q5V3Q6 | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) | 40% | 100% |
| Q6BQ34 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 61% | 93% |
| Q6FN88 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 62% | 94% |
| Q6LZM7 | Methanococcus maripaludis (strain S2 / LL) | 41% | 100% |
| Q74N89 | Nanoarchaeum equitans (strain Kin4-M) | 42% | 100% |
| Q756P0 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 62% | 94% |
| Q80WS3 | Mus musculus | 67% | 97% |
| Q8I1F4 | Drosophila erecta | 68% | 88% |
| Q8SR42 | Encephalitozoon cuniculi (strain GB-M1) | 57% | 100% |
| Q8TTT4 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 43% | 100% |
| Q8TXU9 | Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) | 44% | 100% |
| Q8U4M2 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 47% | 100% |
| Q8ZTI9 | Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) | 47% | 100% |
| Q94AH9 | Arabidopsis thaliana | 69% | 95% |
| Q971W2 | Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) | 46% | 100% |
| Q9FEF8 | Arabidopsis thaliana | 69% | 99% |
| Q9FHB3 | Arabidopsis thaliana | 55% | 100% |
| Q9HE26 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 62% | 94% |
| Q9HH35 | Methanothermobacter wolfeii | 43% | 100% |
| Q9P9M0 | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) | 44% | 100% |
| Q9V2L5 | Pyrococcus abyssi (strain GE5 / Orsay) | 47% | 100% |
| Q9W1V3 | Drosophila melanogaster | 68% | 89% |
| Q9Y9U3 | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) | 45% | 100% |
| V5BFQ9 | Trypanosoma cruzi | 90% | 97% |
| V5BS95 | Trypanosoma cruzi | 67% | 100% |