LeishMANIAdb
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ABC_transporter_putative/GeneDB:LmjF.33.1300

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ABC_transporter_putative/GeneDB:LmjF.33.1300
Gene product:
ABC transporter, putative
Species:
Leishmania donovani
UniProt:
A0A3S5H7U4_LEIDO
TriTrypDb:
LdBPK_331370.1 , LdCL_330020000 , LDHU3_33.2040
Length:
653

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005576 extracellular region 2 2
GO:0005737 cytoplasm 2 1
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 7
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Expansion

Sequence features

A0A3S5H7U4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7U4

Function

Biological processes
TermNameLevelCount
GO:0006468 protein phosphorylation 5 2
GO:0006793 phosphorus metabolic process 3 2
GO:0006796 phosphate-containing compound metabolic process 4 2
GO:0006807 nitrogen compound metabolic process 2 2
GO:0008152 metabolic process 1 2
GO:0009987 cellular process 1 2
GO:0016310 phosphorylation 5 2
GO:0019538 protein metabolic process 3 2
GO:0036211 protein modification process 4 2
GO:0043170 macromolecule metabolic process 3 2
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 2
GO:0003824 catalytic activity 1 2
GO:0004672 protein kinase activity 3 2
GO:0005488 binding 1 2
GO:0005524 ATP binding 5 2
GO:0016301 kinase activity 4 2
GO:0016740 transferase activity 2 2
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 2
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 2
GO:0017076 purine nucleotide binding 4 2
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 503 507 PF00656 0.304
CLV_NRD_NRD_1 125 127 PF00675 0.474
CLV_NRD_NRD_1 180 182 PF00675 0.470
CLV_NRD_NRD_1 214 216 PF00675 0.467
CLV_NRD_NRD_1 397 399 PF00675 0.460
CLV_NRD_NRD_1 455 457 PF00675 0.648
CLV_NRD_NRD_1 629 631 PF00675 0.370
CLV_NRD_NRD_1 9 11 PF00675 0.292
CLV_PCSK_KEX2_1 236 238 PF00082 0.462
CLV_PCSK_KEX2_1 286 288 PF00082 0.452
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IML7 Leptomonas seymouri 27% 100%
A0A0N1PA82 Leptomonas seymouri 67% 100%
A0A0S4KEI7 Bodo saltans 28% 100%
A0A0S4KLC8 Bodo saltans 40% 100%
A0A179HKZ8 Purpureocillium lilacinum 30% 100%
A0A1X0P192 Trypanosomatidae 45% 100%
A0A3R7KBH2 Trypanosoma rangeli 44% 100%
A0A3R7KJM1 Trypanosoma rangeli 31% 100%
A0A3S5H636 Leishmania donovani 29% 100%
A4H590 Leishmania braziliensis 28% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS