Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H7U0_LEIDO

TriTrypDb:

LdBPK_330710.1 , LdCL_330012600 , LDHU3_33.1000

Length:

152


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Could not find GO cellular_component term for this entry.

A0A3S5H7U0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7U0

PDB structure(s): 7aih_Az , 7am2_Az , 7ane_Az


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	91	95	PF00656	0.362
CLV_NRD_NRD_1	104	106	PF00675	0.377
CLV_NRD_NRD_1	132	134	PF00675	0.360
CLV_NRD_NRD_1	48	50	PF00675	0.363
CLV_NRD_NRD_1	8	10	PF00675	0.494
CLV_PCSK_KEX2_1	104	106	PF00082	0.371
CLV_PCSK_KEX2_1	27	29	PF00082	0.446
CLV_PCSK_PC1ET2_1	27	29	PF00082	0.424
CLV_PCSK_SKI1_1	27	31	PF00082	0.441
DEG_Nend_Nbox_1	1	3	PF02207	0.466
DOC_MAPK_gen_1	9	15	PF00069	0.497
DOC_USP7_UBL2_3	120	124	PF12436	0.509
DOC_USP7_UBL2_3	33	37	PF12436	0.474
LIG_deltaCOP1_diTrp_1	111	115	PF00928	0.460
LIG_eIF4E_1	46	52	PF01652	0.357
LIG_FHA_1	108	114	PF00498	0.494
LIG_FHA_1	3	9	PF00498	0.567
LIG_FHA_2	60	66	PF00498	0.400
LIG_LIR_Gen_1	110	117	PF02991	0.523
LIG_LIR_Gen_1	126	132	PF02991	0.239
LIG_LIR_Gen_1	137	147	PF02991	0.392
LIG_LIR_Nem_3	110	115	PF02991	0.539
LIG_LIR_Nem_3	126	130	PF02991	0.259
LIG_LIR_Nem_3	137	143	PF02991	0.392
LIG_LIR_Nem_3	80	86	PF02991	0.370
LIG_Pex14_2	132	136	PF04695	0.352
LIG_SH2_CRK	84	88	PF00017	0.391
LIG_SH2_SRC	140	143	PF00017	0.402
LIG_SH2_SRC	57	60	PF00017	0.462
LIG_SH2_SRC	67	70	PF00017	0.443
LIG_SH2_STAP1	140	144	PF00017	0.402
LIG_SH2_STAP1	63	67	PF00017	0.532
LIG_SH2_STAT3	125	128	PF00017	0.343
LIG_SH2_STAT5	57	60	PF00017	0.462
LIG_SH3_3	103	109	PF00018	0.357
LIG_TRAF2_1	62	65	PF00917	0.414
MOD_CK2_1	59	65	PF00069	0.414
MOD_LATS_1	114	120	PF00433	0.510
MOD_NEK2_1	2	7	PF00069	0.445
MOD_PKA_2	2	8	PF00069	0.472
MOD_Plk_1	136	142	PF00069	0.393
MOD_Plk_2-3	59	65	PF00069	0.394
TRG_ENDOCYTIC_2	140	143	PF00928	0.402
TRG_ER_diArg_1	104	106	PF00400	0.381


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IID2	Leptomonas seymouri	93%	100%
A0A0S4IYG4	Bodo saltans	64%	99%
A0A1X0P0T9	Trypanosomatidae	74%	99%
A0A422N870	Trypanosoma rangeli	78%	99%
A4HLA6	Leishmania braziliensis	93%	100%
A4I8T2	Leishmania infantum	100%	100%
D0A4T0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	74%	99%
E9B3P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4Q4D9	Leishmania major	98%	100%