Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H7T3_LEIDO

TriTrypDb:

LdBPK_323850.1 , LdCL_320044500 , LDHU3_32.4980

Length:

727

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7T3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7T3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	218	222	PF00656	0.624
CLV_C14_Caspase3-7	379	383	PF00656	0.558
CLV_C14_Caspase3-7	66	70	PF00656	0.798
CLV_NRD_NRD_1	172	174	PF00675	0.502
CLV_NRD_NRD_1	250	252	PF00675	0.518
CLV_NRD_NRD_1	523	525	PF00675	0.443
CLV_NRD_NRD_1	527	529	PF00675	0.387
CLV_NRD_NRD_1	641	643	PF00675	0.521
CLV_NRD_NRD_1	712	714	PF00675	0.588
CLV_PCSK_KEX2_1	172	174	PF00082	0.595

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P501	Leptomonas seymouri	63%	86%
A0A0S4JJK2	Bodo saltans	33%	89%
A0A1X0NRY5	Trypanosomatidae	42%	99%
A4HL07	Leishmania braziliensis	81%	100%
A4I8I8	Leishmania infantum	100%	100%
D0AAM9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	98%
E9B3E8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	98%
Q4Q4Q2	Leishmania major	95%	100%
V5BLC8	Trypanosoma cruzi	41%	98%

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