LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S5H7S3_LEIDO
TriTrypDb:
LdBPK_322340.1 , LdCL_320028700 , LDHU3_32.2910
Length:
639

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7S3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7S3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 151 155 PF00656 0.675
CLV_C14_Caspase3-7 217 221 PF00656 0.593
CLV_C14_Caspase3-7 420 424 PF00656 0.599
CLV_NRD_NRD_1 11 13 PF00675 0.626
CLV_NRD_NRD_1 137 139 PF00675 0.724
CLV_NRD_NRD_1 144 146 PF00675 0.671
CLV_NRD_NRD_1 510 512 PF00675 0.787
CLV_PCSK_FUR_1 8 12 PF00082 0.548
CLV_PCSK_KEX2_1 10 12 PF00082 0.594
CLV_PCSK_KEX2_1 137 139 PF00082 0.705
CLV_PCSK_KEX2_1 144 146 PF00082 0.677
CLV_PCSK_KEX2_1 510 512 PF00082 0.787
CLV_PCSK_KEX2_1 7 9 PF00082 0.597
CLV_PCSK_PC1ET2_1 10 12 PF00082 0.594
CLV_PCSK_PC1ET2_1 7 9 PF00082 0.597
CLV_PCSK_SKI1_1 347 351 PF00082 0.625
CLV_PCSK_SKI1_1 544 548 PF00082 0.615
CLV_PCSK_SKI1_1 7 11 PF00082 0.685
DEG_SPOP_SBC_1 248 252 PF00917 0.713
DEG_SPOP_SBC_1 572 576 PF00917 0.653
DOC_CYCLIN_yCln2_LP_2 157 163 PF00134 0.615
DOC_MAPK_FxFP_2 462 465 PF00069 0.804
DOC_MAPK_gen_1 586 594 PF00069 0.652
DOC_MAPK_MEF2A_6 398 406 PF00069 0.653
DOC_PP2B_LxvP_1 157 160 PF13499 0.613
DOC_PP2B_LxvP_1 363 366 PF13499 0.641
DOC_PP4_FxxP_1 399 402 PF00568 0.695
DOC_PP4_FxxP_1 462 465 PF00568 0.804
DOC_USP7_MATH_1 118 122 PF00917 0.700
DOC_USP7_MATH_1 126 130 PF00917 0.673
DOC_USP7_MATH_1 147 151 PF00917 0.679
DOC_USP7_MATH_1 163 167 PF00917 0.553
DOC_USP7_MATH_1 188 192 PF00917 0.655
DOC_USP7_MATH_1 214 218 PF00917 0.587
DOC_USP7_MATH_1 230 234 PF00917 0.709
DOC_USP7_MATH_1 316 320 PF00917 0.721
DOC_USP7_MATH_1 327 331 PF00917 0.580
DOC_USP7_MATH_1 402 406 PF00917 0.641
DOC_USP7_MATH_1 411 415 PF00917 0.682
DOC_USP7_MATH_1 455 459 PF00917 0.660
DOC_USP7_MATH_1 49 53 PF00917 0.664
DOC_USP7_MATH_2 499 505 PF00917 0.592
DOC_WW_Pin1_4 130 135 PF00397 0.744
DOC_WW_Pin1_4 277 282 PF00397 0.653
DOC_WW_Pin1_4 364 369 PF00397 0.692
DOC_WW_Pin1_4 495 500 PF00397 0.712
DOC_WW_Pin1_4 505 510 PF00397 0.620
DOC_WW_Pin1_4 527 532 PF00397 0.659
DOC_WW_Pin1_4 66 71 PF00397 0.614
DOC_WW_Pin1_4 81 86 PF00397 0.607
LIG_14-3-3_CanoR_1 119 127 PF00244 0.595
LIG_14-3-3_CanoR_1 510 514 PF00244 0.595
LIG_APCC_ABBA_1 338 343 PF00400 0.709
LIG_BIR_III_2 60 64 PF00653 0.617
LIG_BRCT_BRCA1_1 607 611 PF00533 0.709
LIG_CtBP_PxDLS_1 374 378 PF00389 0.697
LIG_CtBP_PxDLS_1 514 518 PF00389 0.659
LIG_deltaCOP1_diTrp_1 616 622 PF00928 0.495
LIG_eIF4E_1 541 547 PF01652 0.576
LIG_FHA_1 112 118 PF00498 0.611
LIG_FHA_1 122 128 PF00498 0.569
LIG_FHA_1 233 239 PF00498 0.821
LIG_FHA_1 348 354 PF00498 0.649
LIG_FHA_1 360 366 PF00498 0.546
LIG_FHA_2 15 21 PF00498 0.601
LIG_FHA_2 24 30 PF00498 0.505
LIG_FHA_2 303 309 PF00498 0.682
LIG_FHA_2 316 322 PF00498 0.582
LIG_FHA_2 54 60 PF00498 0.670
LIG_LIR_Apic_2 350 355 PF02991 0.698
LIG_LIR_Apic_2 396 402 PF02991 0.691
LIG_LIR_Gen_1 339 349 PF02991 0.704
LIG_LIR_Gen_1 42 50 PF02991 0.530
LIG_LIR_Gen_1 484 489 PF02991 0.630
LIG_LIR_Nem_3 339 344 PF02991 0.700
LIG_LIR_Nem_3 384 390 PF02991 0.647
LIG_LIR_Nem_3 42 47 PF02991 0.525
LIG_LIR_Nem_3 433 438 PF02991 0.638
LIG_LIR_Nem_3 463 467 PF02991 0.742
LIG_LIR_Nem_3 484 488 PF02991 0.582
LIG_LIR_Nem_3 536 541 PF02991 0.559
LIG_LYPXL_S_1 434 438 PF13949 0.680
LIG_LYPXL_yS_3 435 438 PF13949 0.678
LIG_LYPXL_yS_3 464 467 PF13949 0.801
LIG_MYND_1 436 440 PF01753 0.676
LIG_PTAP_UEV_1 64 69 PF05743 0.586
LIG_Rb_pABgroove_1 605 613 PF01858 0.658
LIG_SH2_CRK 44 48 PF00017 0.611
LIG_SH2_CRK 485 489 PF00017 0.583
LIG_SH2_CRK 528 532 PF00017 0.674
LIG_SH2_NCK_1 497 501 PF00017 0.722
LIG_SH2_NCK_1 528 532 PF00017 0.626
LIG_SH2_NCK_1 566 570 PF00017 0.569
LIG_SH2_SRC 352 355 PF00017 0.702
LIG_SH2_SRC 581 584 PF00017 0.602
LIG_SH2_STAP1 632 636 PF00017 0.542
LIG_SH2_STAT5 352 355 PF00017 0.823
LIG_SH2_STAT5 44 47 PF00017 0.630
LIG_SH2_STAT5 609 612 PF00017 0.639
LIG_SH3_3 235 241 PF00018 0.586
LIG_SH3_3 334 340 PF00018 0.651
LIG_SH3_3 362 368 PF00018 0.688
LIG_SH3_3 433 439 PF00018 0.678
LIG_SH3_3 462 468 PF00018 0.754
LIG_SH3_3 600 606 PF00018 0.675
LIG_SH3_3 62 68 PF00018 0.750
LIG_SUMO_SIM_anti_2 69 75 PF11976 0.524
LIG_SUMO_SIM_par_1 401 407 PF11976 0.575
LIG_SUMO_SIM_par_1 426 433 PF11976 0.661
LIG_WRC_WIRS_1 431 436 PF05994 0.686
MOD_CDC14_SPxK_1 367 370 PF00782 0.698
MOD_CDK_SPK_2 130 135 PF00069 0.714
MOD_CDK_SPK_2 505 510 PF00069 0.674
MOD_CDK_SPxK_1 364 370 PF00069 0.694
MOD_CDK_SPxK_1 505 511 PF00069 0.676
MOD_CDK_SPxxK_3 130 137 PF00069 0.661
MOD_CK1_1 121 127 PF00069 0.600
MOD_CK1_1 130 136 PF00069 0.671
MOD_CK1_1 150 156 PF00069 0.632
MOD_CK1_1 166 172 PF00069 0.577
MOD_CK1_1 173 179 PF00069 0.616
MOD_CK1_1 180 186 PF00069 0.632
MOD_CK1_1 203 209 PF00069 0.713
MOD_CK1_1 218 224 PF00069 0.678
MOD_CK1_1 253 259 PF00069 0.704
MOD_CK1_1 269 275 PF00069 0.733
MOD_CK1_1 277 283 PF00069 0.640
MOD_CK1_1 319 325 PF00069 0.726
MOD_CK1_1 330 336 PF00069 0.618
MOD_CK1_1 430 436 PF00069 0.617
MOD_CK1_1 445 451 PF00069 0.614
MOD_CK2_1 126 132 PF00069 0.694
MOD_CK2_1 14 20 PF00069 0.604
MOD_CK2_1 205 211 PF00069 0.745
MOD_CK2_1 23 29 PF00069 0.503
MOD_CK2_1 315 321 PF00069 0.685
MOD_CK2_1 339 345 PF00069 0.609
MOD_CK2_1 443 449 PF00069 0.652
MOD_CK2_1 495 501 PF00069 0.656
MOD_CK2_1 53 59 PF00069 0.663
MOD_CK2_1 66 72 PF00069 0.557
MOD_CK2_1 81 87 PF00069 0.524
MOD_Cter_Amidation 135 138 PF01082 0.666
MOD_GlcNHglycan 165 168 PF01048 0.704
MOD_GlcNHglycan 184 187 PF01048 0.686
MOD_GlcNHglycan 203 206 PF01048 0.597
MOD_GlcNHglycan 207 210 PF01048 0.710
MOD_GlcNHglycan 216 220 PF01048 0.635
MOD_GlcNHglycan 228 231 PF01048 0.683
MOD_GlcNHglycan 290 293 PF01048 0.747
MOD_GlcNHglycan 321 324 PF01048 0.709
MOD_GlcNHglycan 415 418 PF01048 0.645
MOD_GlcNHglycan 456 460 PF01048 0.689
MOD_GlcNHglycan 575 578 PF01048 0.618
MOD_GlcNHglycan 588 591 PF01048 0.665
MOD_GlcNHglycan 77 80 PF01048 0.735
MOD_GSK3_1 126 133 PF00069 0.715
MOD_GSK3_1 166 173 PF00069 0.646
MOD_GSK3_1 174 181 PF00069 0.636
MOD_GSK3_1 201 208 PF00069 0.665
MOD_GSK3_1 214 221 PF00069 0.651
MOD_GSK3_1 226 233 PF00069 0.728
MOD_GSK3_1 243 250 PF00069 0.575
MOD_GSK3_1 265 272 PF00069 0.735
MOD_GSK3_1 297 304 PF00069 0.761
MOD_GSK3_1 315 322 PF00069 0.606
MOD_GSK3_1 423 430 PF00069 0.620
MOD_GSK3_1 49 56 PF00069 0.635
MOD_GSK3_1 491 498 PF00069 0.682
MOD_GSK3_1 501 508 PF00069 0.648
MOD_GSK3_1 509 516 PF00069 0.585
MOD_GSK3_1 536 543 PF00069 0.718
MOD_GSK3_1 586 593 PF00069 0.729
MOD_N-GLC_1 111 116 PF02516 0.659
MOD_N-GLC_1 269 274 PF02516 0.709
MOD_N-GLC_1 277 282 PF02516 0.629
MOD_N-GLC_1 316 321 PF02516 0.680
MOD_N-GLC_1 584 589 PF02516 0.644
MOD_N-GLC_1 590 595 PF02516 0.615
MOD_NEK2_1 43 48 PF00069 0.609
MOD_NEK2_1 564 569 PF00069 0.613
MOD_NEK2_1 610 615 PF00069 0.592
MOD_NEK2_1 88 93 PF00069 0.594
MOD_NEK2_2 491 496 PF00069 0.650
MOD_NMyristoyl 1 7 PF02799 0.646
MOD_PIKK_1 230 236 PF00454 0.692
MOD_PIKK_1 382 388 PF00454 0.561
MOD_PKA_2 118 124 PF00069 0.682
MOD_PKA_2 14 20 PF00069 0.594
MOD_PKA_2 169 175 PF00069 0.670
MOD_PKA_2 177 183 PF00069 0.610
MOD_PKA_2 23 29 PF00069 0.568
MOD_PKA_2 266 272 PF00069 0.676
MOD_PKA_2 411 417 PF00069 0.596
MOD_PKA_2 509 515 PF00069 0.587
MOD_Plk_1 316 322 PF00069 0.701
MOD_Plk_1 327 333 PF00069 0.624
MOD_Plk_1 491 497 PF00069 0.687
MOD_Plk_1 590 596 PF00069 0.654
MOD_Plk_1 611 617 PF00069 0.632
MOD_Plk_1 88 94 PF00069 0.587
MOD_Plk_2-3 14 20 PF00069 0.580
MOD_Plk_2-3 339 345 PF00069 0.575
MOD_Plk_4 14 20 PF00069 0.592
MOD_Plk_4 327 333 PF00069 0.632
MOD_Plk_4 430 436 PF00069 0.670
MOD_Plk_4 513 519 PF00069 0.661
MOD_Plk_4 536 542 PF00069 0.660
MOD_Plk_4 605 611 PF00069 0.761
MOD_ProDKin_1 130 136 PF00069 0.745
MOD_ProDKin_1 277 283 PF00069 0.652
MOD_ProDKin_1 364 370 PF00069 0.694
MOD_ProDKin_1 495 501 PF00069 0.716
MOD_ProDKin_1 505 511 PF00069 0.622
MOD_ProDKin_1 527 533 PF00069 0.660
MOD_ProDKin_1 66 72 PF00069 0.614
MOD_ProDKin_1 81 87 PF00069 0.609
TRG_ENDOCYTIC_2 341 344 PF00928 0.713
TRG_ENDOCYTIC_2 435 438 PF00928 0.661
TRG_ENDOCYTIC_2 44 47 PF00928 0.606
TRG_ENDOCYTIC_2 464 467 PF00928 0.801
TRG_ENDOCYTIC_2 485 488 PF00928 0.717
TRG_ER_diArg_1 143 145 PF00400 0.664
TRG_ER_diArg_1 509 511 PF00400 0.673
TRG_NLS_MonoExtC_3 6 11 PF00514 0.605

Homologs

Protein Taxonomy Sequence identity Coverage
A4HKK9 Leishmania braziliensis 46% 95%
A4I842 Leishmania infantum 99% 100%
E9B300 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%
Q4Q556 Leishmania major 81% 99%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS