ARID domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H7R3_LEIDO

TriTrypDb:

LdBPK_320610.1 , LdCL_320011600 , LDHU3_32.0760

Length:

587

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7R3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7R3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	165	169	PF00656	0.793
CLV_C14_Caspase3-7	60	64	PF00656	0.408
CLV_NRD_NRD_1	228	230	PF00675	0.684
CLV_NRD_NRD_1	257	259	PF00675	0.574
CLV_NRD_NRD_1	382	384	PF00675	0.830
CLV_NRD_NRD_1	429	431	PF00675	0.777
CLV_NRD_NRD_1	473	475	PF00675	0.637
CLV_NRD_NRD_1	477	479	PF00675	0.626
CLV_NRD_NRD_1	550	552	PF00675	0.634
CLV_NRD_NRD_1	582	584	PF00675	0.470
CLV_NRD_NRD_1	90	92	PF00675	0.403
CLV_PCSK_FUR_1	378	382	PF00082	0.681
CLV_PCSK_FUR_1	87	91	PF00082	0.466
CLV_PCSK_KEX2_1	114	116	PF00082	0.524
CLV_PCSK_KEX2_1	228	230	PF00082	0.753
CLV_PCSK_KEX2_1	241	243	PF00082	0.578
CLV_PCSK_KEX2_1	378	380	PF00082	0.688
CLV_PCSK_KEX2_1	381	383	PF00082	0.702
CLV_PCSK_KEX2_1	428	430	PF00082	0.796
CLV_PCSK_KEX2_1	473	475	PF00082	0.633
CLV_PCSK_KEX2_1	477	479	PF00082	0.630
CLV_PCSK_KEX2_1	550	552	PF00082	0.626
CLV_PCSK_KEX2_1	89	91	PF00082	0.399
CLV_PCSK_PC1ET2_1	114	116	PF00082	0.524
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.618
CLV_PCSK_PC1ET2_1	477	479	PF00082	0.651
CLV_PCSK_PC1ET2_1	550	552	PF00082	0.626
CLV_PCSK_PC1ET2_1	89	91	PF00082	0.399
CLV_PCSK_PC7_1	224	230	PF00082	0.633
CLV_PCSK_PC7_1	378	384	PF00082	0.662
CLV_PCSK_PC7_1	473	479	PF00082	0.649
CLV_PCSK_SKI1_1	115	119	PF00082	0.473
CLV_PCSK_SKI1_1	129	133	PF00082	0.622
CLV_PCSK_SKI1_1	147	151	PF00082	0.579
CLV_PCSK_SKI1_1	229	233	PF00082	0.696
CLV_PCSK_SKI1_1	552	556	PF00082	0.696
CLV_PCSK_SKI1_1	78	82	PF00082	0.442
DOC_MAPK_MEF2A_6	486	495	PF00069	0.597
DOC_PIKK_1	392	400	PF02985	0.551
DOC_PP4_MxPP_1	123	126	PF00568	0.555
DOC_USP7_MATH_1	154	158	PF00917	0.690
DOC_USP7_MATH_1	2	6	PF00917	0.488
DOC_USP7_MATH_1	216	220	PF00917	0.647
DOC_USP7_MATH_1	346	350	PF00917	0.591
DOC_USP7_MATH_1	462	466	PF00917	0.681
DOC_USP7_MATH_1	469	473	PF00917	0.715
DOC_USP7_MATH_1	514	518	PF00917	0.600
DOC_USP7_MATH_1	54	58	PF00917	0.609
DOC_USP7_MATH_1	559	563	PF00917	0.640
DOC_USP7_UBL2_3	114	118	PF12436	0.530
DOC_USP7_UBL2_3	455	459	PF12436	0.649
DOC_USP7_UBL2_3	475	479	PF12436	0.560
DOC_WW_Pin1_4	131	136	PF00397	0.651
DOC_WW_Pin1_4	137	142	PF00397	0.612
DOC_WW_Pin1_4	152	157	PF00397	0.583
DOC_WW_Pin1_4	241	246	PF00397	0.585
DOC_WW_Pin1_4	437	442	PF00397	0.716
DOC_WW_Pin1_4	519	524	PF00397	0.706
LIG_14-3-3_CanoR_1	129	135	PF00244	0.655
LIG_14-3-3_CanoR_1	228	238	PF00244	0.812
LIG_14-3-3_CanoR_1	348	352	PF00244	0.499
LIG_14-3-3_CanoR_1	356	364	PF00244	0.566
LIG_14-3-3_CanoR_1	78	83	PF00244	0.436
LIG_Actin_WH2_2	64	80	PF00022	0.491
LIG_BRCT_BRCA1_1	266	270	PF00533	0.487
LIG_BRCT_BRCA1_1	491	495	PF00533	0.544
LIG_deltaCOP1_diTrp_1	33	42	PF00928	0.405
LIG_FHA_1	17	23	PF00498	0.398
LIG_FHA_1	289	295	PF00498	0.364
LIG_FHA_1	60	66	PF00498	0.412
LIG_FHA_1	71	77	PF00498	0.444
LIG_FHA_1	94	100	PF00498	0.474
LIG_FHA_2	185	191	PF00498	0.624
LIG_FHA_2	195	201	PF00498	0.562
LIG_FHA_2	387	393	PF00498	0.623
LIG_LIR_Apic_2	249	255	PF02991	0.724
LIG_LIR_Apic_2	282	288	PF02991	0.516
LIG_LIR_Apic_2	498	504	PF02991	0.585
LIG_LIR_Gen_1	51	59	PF02991	0.443
LIG_LIR_Gen_1	95	106	PF02991	0.399
LIG_LIR_LC3C_4	349	354	PF02991	0.542
LIG_LIR_Nem_3	110	116	PF02991	0.417
LIG_LIR_Nem_3	305	310	PF02991	0.498
LIG_LIR_Nem_3	33	38	PF02991	0.593
LIG_LIR_Nem_3	51	56	PF02991	0.336
LIG_LIR_Nem_3	95	101	PF02991	0.399
LIG_LYPXL_S_1	43	47	PF13949	0.394
LIG_LYPXL_yS_3	44	47	PF13949	0.406
LIG_PDZ_Class_3	582	587	PF00595	0.535
LIG_Pex14_1	272	276	PF04695	0.421
LIG_PTAP_UEV_1	155	160	PF05743	0.622
LIG_Rb_pABgroove_1	395	403	PF01858	0.551
LIG_SH2_CRK	252	256	PF00017	0.525
LIG_SH2_CRK	501	505	PF00017	0.565
LIG_SH2_NCK_1	501	505	PF00017	0.565
LIG_SH2_PTP2	98	101	PF00017	0.375
LIG_SH2_STAP1	66	70	PF00017	0.401
LIG_SH2_STAT5	276	279	PF00017	0.443
LIG_SH2_STAT5	285	288	PF00017	0.336
LIG_SH2_STAT5	536	539	PF00017	0.457
LIG_SH2_STAT5	98	101	PF00017	0.375
LIG_SH3_2	223	228	PF14604	0.535
LIG_SH3_3	122	128	PF00018	0.562
LIG_SH3_3	153	159	PF00018	0.786
LIG_SH3_3	220	226	PF00018	0.534
LIG_SH3_3	319	325	PF00018	0.439
LIG_SH3_3	73	79	PF00018	0.506
LIG_SH3_3	96	102	PF00018	0.385
LIG_SUMO_SIM_anti_2	349	355	PF11976	0.481
LIG_SUMO_SIM_par_1	349	355	PF11976	0.481
LIG_TRAF2_1	102	105	PF00917	0.399
LIG_TRAF2_1	390	393	PF00917	0.612
LIG_TRAF2_1	545	548	PF00917	0.518
LIG_TYR_ITSM	94	101	PF00017	0.382
LIG_WW_3	126	130	PF00397	0.599
MOD_CDK_SPxK_1	241	247	PF00069	0.589
MOD_CK1_1	133	139	PF00069	0.708
MOD_CK1_1	177	183	PF00069	0.634
MOD_CK1_1	184	190	PF00069	0.596
MOD_CK1_1	214	220	PF00069	0.693
MOD_CK1_1	233	239	PF00069	0.634
MOD_CK1_1	388	394	PF00069	0.626
MOD_CK1_1	517	523	PF00069	0.591
MOD_CK2_1	133	139	PF00069	0.631
MOD_CK2_1	184	190	PF00069	0.661
MOD_CK2_1	194	200	PF00069	0.601
MOD_CK2_1	386	392	PF00069	0.626
MOD_CK2_1	407	413	PF00069	0.647
MOD_CK2_1	54	60	PF00069	0.428
MOD_Cter_Amidation	87	90	PF01082	0.468
MOD_GlcNHglycan	135	138	PF01048	0.666
MOD_GlcNHglycan	156	159	PF01048	0.670
MOD_GlcNHglycan	183	186	PF01048	0.635
MOD_GlcNHglycan	200	206	PF01048	0.692
MOD_GlcNHglycan	218	221	PF01048	0.831
MOD_GlcNHglycan	324	328	PF01048	0.467
MOD_GlcNHglycan	338	341	PF01048	0.583
MOD_GlcNHglycan	464	467	PF01048	0.741
MOD_GlcNHglycan	469	472	PF01048	0.660
MOD_GlcNHglycan	55	59	PF01048	0.446
MOD_GSK3_1	12	19	PF00069	0.498
MOD_GSK3_1	129	136	PF00069	0.690
MOD_GSK3_1	148	155	PF00069	0.542
MOD_GSK3_1	174	181	PF00069	0.633
MOD_GSK3_1	211	218	PF00069	0.634
MOD_GSK3_1	229	236	PF00069	0.737
MOD_GSK3_1	313	320	PF00069	0.436
MOD_GSK3_1	352	359	PF00069	0.559
MOD_GSK3_1	367	374	PF00069	0.626
MOD_GSK3_1	435	442	PF00069	0.604
MOD_GSK3_1	522	529	PF00069	0.476
MOD_GSK3_1	532	539	PF00069	0.455
MOD_GSK3_1	54	61	PF00069	0.451
MOD_LATS_1	227	233	PF00433	0.651
MOD_N-GLC_1	317	322	PF02516	0.439
MOD_N-GLC_1	48	53	PF02516	0.437
MOD_NEK2_1	119	124	PF00069	0.525
MOD_NEK2_1	178	183	PF00069	0.606
MOD_NEK2_1	311	316	PF00069	0.435
MOD_NEK2_1	352	357	PF00069	0.494
MOD_NEK2_1	566	571	PF00069	0.555
MOD_PIKK_1	178	184	PF00454	0.635
MOD_PIKK_1	421	427	PF00454	0.619
MOD_PKA_1	258	264	PF00069	0.534
MOD_PKA_1	550	556	PF00069	0.633
MOD_PKA_2	246	252	PF00069	0.607
MOD_PKA_2	279	285	PF00069	0.434
MOD_PKA_2	347	353	PF00069	0.510
MOD_PKA_2	355	361	PF00069	0.546
MOD_PKA_2	371	377	PF00069	0.680
MOD_PKA_2	550	556	PF00069	0.629
MOD_Plk_1	119	125	PF00069	0.534
MOD_Plk_1	16	22	PF00069	0.417
MOD_Plk_1	566	572	PF00069	0.533
MOD_Plk_1	94	100	PF00069	0.472
MOD_Plk_2-3	407	413	PF00069	0.665
MOD_Plk_4	145	151	PF00069	0.666
MOD_Plk_4	16	22	PF00069	0.417
MOD_Plk_4	174	180	PF00069	0.673
MOD_Plk_4	247	253	PF00069	0.725
MOD_Plk_4	347	353	PF00069	0.491
MOD_Plk_4	522	528	PF00069	0.469
MOD_Plk_4	566	572	PF00069	0.533
MOD_Plk_4	94	100	PF00069	0.407
MOD_ProDKin_1	131	137	PF00069	0.651
MOD_ProDKin_1	152	158	PF00069	0.690
MOD_ProDKin_1	241	247	PF00069	0.589
MOD_ProDKin_1	437	443	PF00069	0.717
MOD_ProDKin_1	519	525	PF00069	0.700
MOD_SUMO_for_1	117	120	PF00179	0.477
MOD_SUMO_for_1	454	457	PF00179	0.645
MOD_SUMO_for_1	515	518	PF00179	0.557
MOD_SUMO_rev_2	104	109	PF00179	0.398
MOD_SUMO_rev_2	139	149	PF00179	0.729
MOD_SUMO_rev_2	163	172	PF00179	0.650
MOD_SUMO_rev_2	33	38	PF00179	0.484
TRG_DiLeu_BaEn_4	104	110	PF01217	0.399
TRG_ENDOCYTIC_2	44	47	PF00928	0.406
TRG_ENDOCYTIC_2	98	101	PF00928	0.375
TRG_ER_diArg_1	378	381	PF00400	0.688
TRG_ER_diArg_1	428	430	PF00400	0.762
TRG_NES_CRM1_1	108	120	PF08389	0.504
TRG_NLS_MonoCore_2	451	456	PF00514	0.656
TRG_NLS_MonoCore_2	88	93	PF00514	0.403
TRG_NLS_MonoExtC_3	451	457	PF00514	0.629
TRG_NLS_MonoExtN_4	549	554	PF00514	0.679
TRG_NLS_MonoExtN_4	87	93	PF00514	0.408
TRG_Pf-PMV_PEXEL_1	107	111	PF00026	0.408
TRG_Pf-PMV_PEXEL_1	29	33	PF00026	0.511

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1J1	Leptomonas seymouri	55%	100%
A4HK39	Leishmania braziliensis	77%	98%
A4I7M4	Leishmania infantum	99%	100%
E9B2I1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	99%
Q4Q5M5	Leishmania major	94%	100%