LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H7L9_LEIDO
TriTrypDb:
LdBPK_292590.1 , LdCL_290032000 , LDHU3_29.3840
Length:
846

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7L9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7L9

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 136 140 PF00656 0.684
CLV_C14_Caspase3-7 224 228 PF00656 0.641
CLV_C14_Caspase3-7 292 296 PF00656 0.621
CLV_C14_Caspase3-7 301 305 PF00656 0.575
CLV_C14_Caspase3-7 561 565 PF00656 0.548
CLV_NRD_NRD_1 196 198 PF00675 0.580
CLV_NRD_NRD_1 366 368 PF00675 0.682
CLV_NRD_NRD_1 504 506 PF00675 0.790
CLV_NRD_NRD_1 551 553 PF00675 0.546
CLV_NRD_NRD_1 562 564 PF00675 0.422
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Homologs

ProteinTaxonomySequence identityCoverage
A4HHP7 Leishmania braziliensis 52% 100%
A4I4W2 Leishmania infantum 99% 100%
E9AEB0 Leishmania major 88% 100%
E9ALH6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS