LeishMANIAdb
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Retrotransposon hot spot (RHS) protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Retrotransposon hot spot (RHS) protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H7L4_LEIDO
TriTrypDb:
LdCL_290023000
Length:
158

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A0A3S5H7L4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7L4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 28 30 PF00675 0.380
CLV_PCSK_KEX2_1 28 30 PF00082 0.380
CLV_PCSK_SKI1_1 14 18 PF00082 0.360
CLV_PCSK_SKI1_1 57 61 PF00082 0.340
DEG_Nend_UBRbox_1 1 4 PF02207 0.567
DOC_CKS1_1 20 25 PF01111 0.568
DOC_PP1_RVXF_1 55 61 PF00149 0.543
DOC_PP1_RVXF_1 9 16 PF00149 0.554
DOC_PP4_FxxP_1 16 19 PF00568 0.558
DOC_PP4_FxxP_1 71 74 PF00568 0.567
DOC_USP7_MATH_1 149 153 PF00917 0.378
DOC_WW_Pin1_4 114 119 PF00397 0.354
DOC_WW_Pin1_4 19 24 PF00397 0.567
LIG_14-3-3_CanoR_1 14 19 PF00244 0.560
LIG_14-3-3_CanoR_1 28 32 PF00244 0.578
LIG_14-3-3_CanoR_1 75 81 PF00244 0.571
LIG_APCC_ABBA_1 107 112 PF00400 0.364
LIG_APCC_ABBA_1 130 135 PF00400 0.325
LIG_LIR_Apic_2 17 23 PF02991 0.565
LIG_SH2_CRK 20 24 PF00017 0.567
LIG_SH2_NCK_1 20 24 PF00017 0.567
LIG_SH2_STAP1 31 35 PF00017 0.568
LIG_SH2_STAT5 8 11 PF00017 0.555
LIG_SH3_1 20 26 PF00018 0.568
LIG_SH3_2 23 28 PF14604 0.571
LIG_SH3_3 117 123 PF00018 0.347
LIG_SH3_3 126 132 PF00018 0.336
LIG_SH3_3 20 26 PF00018 0.568
LIG_SUMO_SIM_anti_2 103 109 PF11976 0.364
MOD_GlcNHglycan 153 156 PF01048 0.576
MOD_GSK3_1 27 34 PF00069 0.575
MOD_GSK3_1 76 83 PF00069 0.563
MOD_N-GLC_2 52 54 PF02516 0.355
MOD_NEK2_2 9 14 PF00069 0.552
MOD_PKA_2 27 33 PF00069 0.575
MOD_PKA_2 76 82 PF00069 0.565
MOD_Plk_1 138 144 PF00069 0.345
MOD_Plk_4 76 82 PF00069 0.565
MOD_ProDKin_1 114 120 PF00069 0.352
MOD_ProDKin_1 19 25 PF00069 0.567
TRG_ER_diArg_1 1 4 PF00400 0.567
TRG_ER_diArg_1 140 143 PF00400 0.342
TRG_ER_diArg_1 74 77 PF00400 0.574
TRG_Pf-PMV_PEXEL_1 151 156 PF00026 0.577

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS