Hypothetical_protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S5H7K8_LEIDO

TriTrypDb:

LdCL_290012500 , LDHU3_29.1060

Length:

249

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7K8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7K8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	225	229	PF00656	0.570
CLV_NRD_NRD_1	131	133	PF00675	0.561
CLV_NRD_NRD_1	164	166	PF00675	0.548
CLV_NRD_NRD_1	56	58	PF00675	0.521
CLV_PCSK_FUR_1	54	58	PF00082	0.460
CLV_PCSK_KEX2_1	131	133	PF00082	0.561
CLV_PCSK_KEX2_1	154	156	PF00082	0.593
CLV_PCSK_KEX2_1	164	166	PF00082	0.515
CLV_PCSK_KEX2_1	236	238	PF00082	0.488
CLV_PCSK_KEX2_1	56	58	PF00082	0.521
CLV_PCSK_PC1ET2_1	154	156	PF00082	0.566
CLV_PCSK_PC1ET2_1	236	238	PF00082	0.488
CLV_PCSK_SKI1_1	131	135	PF00082	0.556
CLV_PCSK_SKI1_1	145	149	PF00082	0.499
CLV_PCSK_SKI1_1	154	158	PF00082	0.519
DEG_SPOP_SBC_1	156	160	PF00917	0.564
DOC_MAPK_gen_1	86	94	PF00069	0.466
DOC_USP7_MATH_1	138	142	PF00917	0.552
DOC_USP7_MATH_1	156	160	PF00917	0.488
DOC_USP7_MATH_1	59	63	PF00917	0.531
DOC_WW_Pin1_4	134	139	PF00397	0.543
DOC_WW_Pin1_4	157	162	PF00397	0.541
DOC_WW_Pin1_4	170	175	PF00397	0.553
DOC_WW_Pin1_4	199	204	PF00397	0.562
LIG_14-3-3_CanoR_1	155	161	PF00244	0.544
LIG_14-3-3_CanoR_1	181	189	PF00244	0.507
LIG_14-3-3_CanoR_1	57	65	PF00244	0.578
LIG_BIR_II_1	1	5	PF00653	0.499
LIG_FHA_2	12	18	PF00498	0.422
LIG_FHA_2	38	44	PF00498	0.500
LIG_LIR_Gen_1	89	98	PF02991	0.475
LIG_LIR_Nem_3	89	94	PF02991	0.468
LIG_PCNA_PIPBox_1	238	247	PF02747	0.505
LIG_PCNA_yPIPBox_3	236	245	PF02747	0.486
LIG_RPA_C_Fungi	52	64	PF08784	0.458
LIG_SH2_STAP1	18	22	PF00017	0.430
LIG_SH2_STAT3	87	90	PF00017	0.476
LIG_SH2_STAT5	25	28	PF00017	0.439
LIG_SH3_3	188	194	PF00018	0.505
LIG_SUMO_SIM_anti_2	187	192	PF11976	0.506
LIG_SUMO_SIM_anti_2	75	83	PF11976	0.671
LIG_SUMO_SIM_par_1	132	137	PF11976	0.561
LIG_SUMO_SIM_par_1	187	192	PF11976	0.506
LIG_TRAF2_1	14	17	PF00917	0.392
MOD_CDC14_SPxK_1	202	205	PF00782	0.567
MOD_CDK_SPxK_1	199	205	PF00069	0.564
MOD_CDK_SPxxK_3	157	164	PF00069	0.519
MOD_CDK_SPxxK_3	170	177	PF00069	0.608
MOD_CK1_1	100	106	PF00069	0.538
MOD_CK1_1	159	165	PF00069	0.613
MOD_CK1_1	173	179	PF00069	0.475
MOD_CK1_1	192	198	PF00069	0.508
MOD_CK1_1	49	55	PF00069	0.630
MOD_CK2_1	11	17	PF00069	0.440
MOD_CK2_1	119	125	PF00069	0.557
MOD_CK2_1	44	50	PF00069	0.682
MOD_CK2_1	66	72	PF00069	0.530
MOD_Cter_Amidation	129	132	PF01082	0.557
MOD_GlcNHglycan	138	141	PF01048	0.551
MOD_GlcNHglycan	194	197	PF01048	0.638
MOD_GlcNHglycan	206	209	PF01048	0.504
MOD_GlcNHglycan	28	31	PF01048	0.473
MOD_GSK3_1	134	141	PF00069	0.603
MOD_GSK3_1	145	152	PF00069	0.498
MOD_GSK3_1	155	162	PF00069	0.533
MOD_GSK3_1	169	176	PF00069	0.492
MOD_GSK3_1	180	187	PF00069	0.496
MOD_GSK3_1	192	199	PF00069	0.537
MOD_GSK3_1	24	31	PF00069	0.502
MOD_GSK3_1	96	103	PF00069	0.514
MOD_NEK2_1	216	221	PF00069	0.564
MOD_NEK2_1	44	49	PF00069	0.524
MOD_PIKK_1	138	144	PF00454	0.550
MOD_PIKK_1	176	182	PF00454	0.548
MOD_PIKK_1	189	195	PF00454	0.663
MOD_PIKK_1	217	223	PF00454	0.566
MOD_PKA_1	154	160	PF00069	0.567
MOD_PKA_2	154	160	PF00069	0.548
MOD_PKA_2	176	182	PF00069	0.596
MOD_Plk_1	145	151	PF00069	0.562
MOD_Plk_4	184	190	PF00069	0.505
MOD_ProDKin_1	134	140	PF00069	0.542
MOD_ProDKin_1	157	163	PF00069	0.540
MOD_ProDKin_1	170	176	PF00069	0.552
MOD_ProDKin_1	199	205	PF00069	0.564
TRG_DiLeu_BaEn_1	76	81	PF01217	0.687
TRG_ER_diArg_1	131	133	PF00400	0.511
TRG_ER_diArg_1	237	240	PF00400	0.500
TRG_ER_diArg_1	54	57	PF00400	0.457
TRG_NLS_MonoExtN_4	151	157	PF00514	0.562

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8C8	Leptomonas seymouri	40%	100%