DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

tfiih basal transcription factor complex helicase xpb subunit

Species:

Leishmania donovani

UniProt:

A0A3S5H7K7_LEIDO

TriTrypDb:

LdBPK_290610.1 , LdCL_290010900 , LDHU3_29.0840

Length:

1106

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000109	nucleotide-excision repair complex	3	1
GO:0000112	nucleotide-excision repair factor 3 complex	4	1
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005667	transcription regulator complex	2	1
GO:0005675	transcription factor TFIIH holo complex	4	1
GO:0005737	cytoplasm	2	1
GO:0032806	carboxy-terminal domain protein kinase complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0032993	protein-DNA complex	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	1
GO:0090575	RNA polymerase II transcription regulator complex	3	1
GO:0097550	transcription preinitiation complex	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1902554	serine/threonine protein kinase complex	6	1
GO:1902911	protein kinase complex	5	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

A0A3S5H7K7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7K7

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	5
GO:0006352	DNA-templated transcription initiation	6	5
GO:0006367	transcription initiation at RNA polymerase II promoter	7	5
GO:0006725	cellular aromatic compound metabolic process	3	5
GO:0006807	nitrogen compound metabolic process	2	5
GO:0008152	metabolic process	1	5
GO:0009058	biosynthetic process	2	5
GO:0009059	macromolecule biosynthetic process	4	5
GO:0009987	cellular process	1	5
GO:0016070	RNA metabolic process	5	5
GO:0018130	heterocycle biosynthetic process	4	5
GO:0019438	aromatic compound biosynthetic process	4	5
GO:0032774	RNA biosynthetic process	5	5
GO:0033683	obsolete nucleotide-excision repair, DNA incision	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	5
GO:0034654	nucleobase-containing compound biosynthetic process	4	5
GO:0043170	macromolecule metabolic process	3	5
GO:0044237	cellular metabolic process	2	5
GO:0044238	primary metabolic process	2	5
GO:0044249	cellular biosynthetic process	3	5
GO:0044271	cellular nitrogen compound biosynthetic process	4	5
GO:0046483	heterocycle metabolic process	3	5
GO:0071704	organic substance metabolic process	2	5
GO:0090304	nucleic acid metabolic process	4	5
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	1
GO:1901360	organic cyclic compound metabolic process	3	5
GO:1901362	organic cyclic compound biosynthetic process	4	5
GO:1901576	organic substance biosynthetic process	3	5
GO:0006259	DNA metabolic process	4	4
GO:0006281	DNA repair	5	4
GO:0006289	nucleotide-excision repair	6	4
GO:0006950	response to stress	2	4
GO:0006974	DNA damage response	4	4
GO:0033554	cellular response to stress	3	4
GO:0044260	obsolete cellular macromolecule metabolic process	3	4
GO:0050896	response to stimulus	1	4
GO:0051716	cellular response to stimulus	2	4

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	11
GO:0003677	DNA binding	4	11
GO:0003678	DNA helicase activity	3	11
GO:0003824	catalytic activity	1	11
GO:0004386	helicase activity	2	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0008094	ATP-dependent activity, acting on DNA	2	11
GO:0016787	hydrolase activity	2	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140097	catalytic activity, acting on DNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:0140657	ATP-dependent activity	1	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11
GO:0003700	DNA-binding transcription factor activity	2	1
GO:0043138	3'-5' DNA helicase activity	4	1
GO:0140110	transcription regulator activity	1	1
GO:0016462	pyrophosphatase activity	5	2
GO:0016817	hydrolase activity, acting on acid anhydrides	3	2
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	2
GO:0016887	ATP hydrolysis activity	7	2
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1033	1037	PF00656	0.592
CLV_C14_Caspase3-7	187	191	PF00656	0.726
CLV_C14_Caspase3-7	730	734	PF00656	0.751
CLV_MEL_PAP_1	837	843	PF00089	0.335
CLV_NRD_NRD_1	1058	1060	PF00675	0.450
CLV_NRD_NRD_1	1061	1063	PF00675	0.468
CLV_NRD_NRD_1	293	295	PF00675	0.655
CLV_NRD_NRD_1	493	495	PF00675	0.411
CLV_NRD_NRD_1	813	815	PF00675	0.273
CLV_NRD_NRD_1	864	866	PF00675	0.335
CLV_PCSK_FUR_1	1056	1060	PF00082	0.580
CLV_PCSK_FUR_1	291	295	PF00082	0.640
CLV_PCSK_KEX2_1	1058	1060	PF00082	0.450
CLV_PCSK_KEX2_1	1061	1063	PF00082	0.468
CLV_PCSK_KEX2_1	173	175	PF00082	0.762
CLV_PCSK_KEX2_1	293	295	PF00082	0.653
CLV_PCSK_KEX2_1	577	579	PF00082	0.354
CLV_PCSK_KEX2_1	715	717	PF00082	0.735
CLV_PCSK_KEX2_1	813	815	PF00082	0.273
CLV_PCSK_KEX2_1	864	866	PF00082	0.335
CLV_PCSK_KEX2_1	905	907	PF00082	0.447
CLV_PCSK_PC1ET2_1	173	175	PF00082	0.762
CLV_PCSK_PC1ET2_1	577	579	PF00082	0.408
CLV_PCSK_PC1ET2_1	715	717	PF00082	0.783
CLV_PCSK_PC1ET2_1	905	907	PF00082	0.447
CLV_PCSK_SKI1_1	219	223	PF00082	0.648
CLV_PCSK_SKI1_1	357	361	PF00082	0.502
CLV_PCSK_SKI1_1	370	374	PF00082	0.395
CLV_PCSK_SKI1_1	440	444	PF00082	0.452
CLV_PCSK_SKI1_1	509	513	PF00082	0.335
CLV_PCSK_SKI1_1	539	543	PF00082	0.354
CLV_PCSK_SKI1_1	590	594	PF00082	0.398
CLV_PCSK_SKI1_1	627	631	PF00082	0.447
CLV_PCSK_SKI1_1	695	699	PF00082	0.573
DEG_APCC_DBOX_1	345	353	PF00400	0.532
DEG_APCC_DBOX_1	369	377	PF00400	0.477
DEG_APCC_DBOX_1	589	597	PF00400	0.447
DEG_Nend_UBRbox_3	1	3	PF02207	0.550
DEG_SPOP_SBC_1	1050	1054	PF00917	0.491
DOC_CDC14_PxL_1	1017	1025	PF14671	0.659
DOC_CKS1_1	222	227	PF01111	0.705
DOC_CKS1_1	243	248	PF01111	0.694
DOC_CYCLIN_RxL_1	213	224	PF00134	0.712
DOC_CYCLIN_RxL_1	755	764	PF00134	0.479
DOC_CYCLIN_yCln2_LP_2	217	223	PF00134	0.704
DOC_MAPK_DCC_7	357	365	PF00069	0.483
DOC_MAPK_DCC_7	464	473	PF00069	0.488
DOC_MAPK_gen_1	492	502	PF00069	0.409
DOC_MAPK_gen_1	560	568	PF00069	0.447
DOC_MAPK_gen_1	625	632	PF00069	0.361
DOC_MAPK_JIP1_4	399	405	PF00069	0.695
DOC_MAPK_MEF2A_6	250	257	PF00069	0.652
DOC_MAPK_MEF2A_6	464	473	PF00069	0.488
DOC_MAPK_MEF2A_6	840	848	PF00069	0.335
DOC_PP1_RVXF_1	1027	1033	PF00149	0.546
DOC_PP1_RVXF_1	786	793	PF00149	0.335
DOC_PP2B_LxvP_1	466	469	PF13499	0.575
DOC_PP2B_LxvP_1	806	809	PF13499	0.335
DOC_PP2B_LxvP_1	846	849	PF13499	0.335
DOC_PP4_FxxP_1	359	362	PF00568	0.435
DOC_USP7_MATH_1	1010	1014	PF00917	0.587
DOC_USP7_MATH_1	1051	1055	PF00917	0.485
DOC_USP7_MATH_1	118	122	PF00917	0.754
DOC_USP7_MATH_1	156	160	PF00917	0.795
DOC_USP7_MATH_1	161	165	PF00917	0.751
DOC_USP7_MATH_1	191	195	PF00917	0.788
DOC_USP7_MATH_1	204	208	PF00917	0.686
DOC_USP7_MATH_1	315	319	PF00917	0.767
DOC_USP7_MATH_1	421	425	PF00917	0.715
DOC_USP7_MATH_1	586	590	PF00917	0.436
DOC_USP7_MATH_1	751	755	PF00917	0.621
DOC_USP7_MATH_1	849	853	PF00917	0.335
DOC_USP7_MATH_1	898	902	PF00917	0.479
DOC_USP7_MATH_1	954	958	PF00917	0.717
DOC_USP7_UBL2_3	169	173	PF12436	0.768
DOC_WW_Pin1_4	1006	1011	PF00397	0.551
DOC_WW_Pin1_4	152	157	PF00397	0.771
DOC_WW_Pin1_4	206	211	PF00397	0.696
DOC_WW_Pin1_4	221	226	PF00397	0.556
DOC_WW_Pin1_4	231	236	PF00397	0.759
DOC_WW_Pin1_4	242	247	PF00397	0.788
DOC_WW_Pin1_4	376	381	PF00397	0.669
DOC_WW_Pin1_4	406	411	PF00397	0.602
DOC_WW_Pin1_4	419	424	PF00397	0.725
DOC_WW_Pin1_4	781	786	PF00397	0.335
DOC_WW_Pin1_4	952	957	PF00397	0.722
LIG_14-3-3_CanoR_1	1011	1020	PF00244	0.666
LIG_14-3-3_CanoR_1	107	113	PF00244	0.673
LIG_14-3-3_CanoR_1	1087	1091	PF00244	0.643
LIG_14-3-3_CanoR_1	130	137	PF00244	0.539
LIG_14-3-3_CanoR_1	250	256	PF00244	0.617
LIG_14-3-3_CanoR_1	302	307	PF00244	0.763
LIG_14-3-3_CanoR_1	314	318	PF00244	0.736
LIG_14-3-3_CanoR_1	370	380	PF00244	0.511
LIG_14-3-3_CanoR_1	761	770	PF00244	0.410
LIG_14-3-3_CanoR_1	906	910	PF00244	0.351
LIG_14-3-3_CanoR_1	924	932	PF00244	0.386
LIG_14-3-3_CanoR_1	995	1001	PF00244	0.603
LIG_APCC_ABBA_1	789	794	PF00400	0.336
LIG_APCC_ABBAyCdc20_2	718	724	PF00400	0.759
LIG_APCC_ABBAyCdc20_2	788	794	PF00400	0.335
LIG_BIR_III_4	750	754	PF00653	0.572
LIG_BRCT_BRCA1_1	118	122	PF00533	0.754
LIG_Clathr_ClatBox_1	603	607	PF01394	0.354
LIG_CtBP_PxDLS_1	268	272	PF00389	0.537
LIG_deltaCOP1_diTrp_1	1026	1032	PF00928	0.449
LIG_FHA_1	1041	1047	PF00498	0.519
LIG_FHA_1	136	142	PF00498	0.748
LIG_FHA_1	17	23	PF00498	0.527
LIG_FHA_1	209	215	PF00498	0.681
LIG_FHA_1	324	330	PF00498	0.676
LIG_FHA_1	382	388	PF00498	0.762
LIG_FHA_1	463	469	PF00498	0.467
LIG_FHA_1	520	526	PF00498	0.448
LIG_FHA_1	54	60	PF00498	0.504
LIG_FHA_1	554	560	PF00498	0.346
LIG_FHA_1	692	698	PF00498	0.547
LIG_FHA_1	771	777	PF00498	0.341
LIG_FHA_1	819	825	PF00498	0.393
LIG_FHA_1	895	901	PF00498	0.341
LIG_FHA_1	958	964	PF00498	0.698
LIG_FHA_1	995	1001	PF00498	0.568
LIG_FHA_2	146	152	PF00498	0.666
LIG_FHA_2	412	418	PF00498	0.751
LIG_IBAR_NPY_1	766	768	PF08397	0.354
LIG_LIR_Apic_2	358	362	PF02991	0.446
LIG_LIR_Apic_2	972	978	PF02991	0.544
LIG_LIR_Gen_1	1031	1038	PF02991	0.586
LIG_LIR_Gen_1	444	454	PF02991	0.505
LIG_LIR_Gen_1	455	466	PF02991	0.406
LIG_LIR_Gen_1	569	576	PF02991	0.335
LIG_LIR_Gen_1	656	667	PF02991	0.409
LIG_LIR_Gen_1	687	696	PF02991	0.421
LIG_LIR_Gen_1	927	936	PF02991	0.585
LIG_LIR_Nem_3	1031	1035	PF02991	0.523
LIG_LIR_Nem_3	1040	1044	PF02991	0.413
LIG_LIR_Nem_3	166	171	PF02991	0.577
LIG_LIR_Nem_3	444	450	PF02991	0.460
LIG_LIR_Nem_3	455	460	PF02991	0.438
LIG_LIR_Nem_3	569	574	PF02991	0.335
LIG_LIR_Nem_3	623	629	PF02991	0.479
LIG_LIR_Nem_3	656	662	PF02991	0.391
LIG_LIR_Nem_3	687	691	PF02991	0.574
LIG_LIR_Nem_3	750	755	PF02991	0.564
LIG_LIR_Nem_3	927	932	PF02991	0.531
LIG_LYPXL_SIV_4	17	25	PF13949	0.531
LIG_LYPXL_yS_3	1020	1023	PF13949	0.649
LIG_Pex14_1	1028	1032	PF04695	0.446
LIG_Pex14_1	537	541	PF04695	0.335
LIG_Rb_LxCxE_1	23	39	PF01857	0.561
LIG_SH2_CRK	571	575	PF00017	0.335
LIG_SH2_CRK	626	630	PF00017	0.378
LIG_SH2_CRK	752	756	PF00017	0.539
LIG_SH2_CRK	890	894	PF00017	0.335
LIG_SH2_CRK	917	921	PF00017	0.354
LIG_SH2_CRK	971	975	PF00017	0.445
LIG_SH2_NCK_1	890	894	PF00017	0.335
LIG_SH2_STAP1	18	22	PF00017	0.536
LIG_SH2_STAP1	57	61	PF00017	0.473
LIG_SH2_STAP1	571	575	PF00017	0.408
LIG_SH2_STAP1	655	659	PF00017	0.384
LIG_SH2_STAT3	339	342	PF00017	0.543
LIG_SH2_STAT3	37	40	PF00017	0.387
LIG_SH2_STAT3	430	433	PF00017	0.425
LIG_SH2_STAT3	904	907	PF00017	0.354
LIG_SH2_STAT5	18	21	PF00017	0.517
LIG_SH2_STAT5	339	342	PF00017	0.431
LIG_SH2_STAT5	795	798	PF00017	0.447
LIG_SH2_STAT5	826	829	PF00017	0.335
LIG_SH2_STAT5	888	891	PF00017	0.337
LIG_SH3_3	1032	1038	PF00018	0.598
LIG_SH3_3	150	156	PF00018	0.618
LIG_SH3_3	217	223	PF00018	0.739
LIG_SH3_3	254	260	PF00018	0.649
LIG_SH3_3	284	290	PF00018	0.487
LIG_SH3_3	673	679	PF00018	0.404
LIG_SH3_3	874	880	PF00018	0.363
LIG_SH3_3	936	942	PF00018	0.486
LIG_Sin3_3	983	990	PF02671	0.578
LIG_SUMO_SIM_anti_2	254	259	PF11976	0.644
LIG_SUMO_SIM_par_1	1042	1048	PF11976	0.606
LIG_SUMO_SIM_par_1	602	608	PF11976	0.335
LIG_SUMO_SIM_par_1	76	82	PF11976	0.553
LIG_TRAF2_1	1013	1016	PF00917	0.672
LIG_TRAF2_1	1076	1079	PF00917	0.622
LIG_TRAF2_1	108	111	PF00917	0.719
LIG_TRAF2_1	585	588	PF00917	0.408
LIG_TRAF2_1	73	76	PF00917	0.696
LIG_TYR_ITIM	624	629	PF00017	0.378
LIG_TYR_ITIM	969	974	PF00017	0.541
LIG_TYR_ITSM	567	574	PF00017	0.447
MOD_CDK_SPK_2	1006	1011	PF00069	0.532
MOD_CDK_SPK_2	406	411	PF00069	0.546
MOD_CDK_SPxxK_3	206	213	PF00069	0.724
MOD_CDK_SPxxK_3	781	788	PF00069	0.335
MOD_CK1_1	1024	1030	PF00069	0.596
MOD_CK1_1	164	170	PF00069	0.781
MOD_CK1_1	209	215	PF00069	0.710
MOD_CK1_1	234	240	PF00069	0.728
MOD_CK1_1	305	311	PF00069	0.715
MOD_CK1_1	313	319	PF00069	0.764
MOD_CK1_1	46	52	PF00069	0.468
MOD_CK1_1	754	760	PF00069	0.404
MOD_CK1_1	894	900	PF00069	0.335
MOD_CK1_1	957	963	PF00069	0.700
MOD_CK1_1	97	103	PF00069	0.704
MOD_CK2_1	1010	1016	PF00069	0.656
MOD_CK2_1	1051	1057	PF00069	0.624
MOD_CK2_1	1100	1106	PF00069	0.739
MOD_CK2_1	191	197	PF00069	0.673
MOD_CK2_1	236	242	PF00069	0.781
MOD_CK2_1	24	30	PF00069	0.430
MOD_CK2_1	411	417	PF00069	0.717
MOD_CK2_1	731	737	PF00069	0.811
MOD_CK2_1	813	819	PF00069	0.354
MOD_Cter_Amidation	492	495	PF01082	0.376
MOD_Cter_Amidation	713	716	PF01082	0.755
MOD_GlcNHglycan	158	161	PF01048	0.791
MOD_GlcNHglycan	186	189	PF01048	0.776
MOD_GlcNHglycan	193	196	PF01048	0.784
MOD_GlcNHglycan	206	209	PF01048	0.436
MOD_GlcNHglycan	226	229	PF01048	0.805
MOD_GlcNHglycan	423	426	PF01048	0.668
MOD_GlcNHglycan	48	51	PF01048	0.434
MOD_GlcNHglycan	5	8	PF01048	0.594
MOD_GlcNHglycan	632	635	PF01048	0.335
MOD_GlcNHglycan	857	860	PF01048	0.354
MOD_GlcNHglycan	952	955	PF01048	0.690
MOD_GlcNHglycan	99	102	PF01048	0.700
MOD_GSK3_1	1006	1013	PF00069	0.559
MOD_GSK3_1	1024	1031	PF00069	0.519
MOD_GSK3_1	1077	1084	PF00069	0.649
MOD_GSK3_1	1096	1103	PF00069	0.682
MOD_GSK3_1	112	119	PF00069	0.735
MOD_GSK3_1	137	144	PF00069	0.734
MOD_GSK3_1	152	159	PF00069	0.756
MOD_GSK3_1	191	198	PF00069	0.726
MOD_GSK3_1	204	211	PF00069	0.643
MOD_GSK3_1	298	305	PF00069	0.739
MOD_GSK3_1	306	313	PF00069	0.755
MOD_GSK3_1	419	426	PF00069	0.710
MOD_GSK3_1	42	49	PF00069	0.481
MOD_GSK3_1	516	523	PF00069	0.411
MOD_GSK3_1	878	885	PF00069	0.340
MOD_GSK3_1	894	901	PF00069	0.312
MOD_GSK3_1	948	955	PF00069	0.678
MOD_N-GLC_1	145	150	PF02516	0.661
MOD_N-GLC_1	164	169	PF02516	0.524
MOD_N-GLC_1	530	535	PF02516	0.391
MOD_N-GLC_1	97	102	PF02516	0.731
MOD_N-GLC_2	884	886	PF02516	0.354
MOD_NEK2_1	1065	1070	PF00069	0.659
MOD_NEK2_1	137	142	PF00069	0.698
MOD_NEK2_1	145	150	PF00069	0.729
MOD_NEK2_1	24	29	PF00069	0.429
MOD_NEK2_1	298	303	PF00069	0.757
MOD_NEK2_1	306	311	PF00069	0.647
MOD_NEK2_1	340	345	PF00069	0.479
MOD_NEK2_1	381	386	PF00069	0.742
MOD_NEK2_1	43	48	PF00069	0.457
MOD_NEK2_1	520	525	PF00069	0.415
MOD_NEK2_1	567	572	PF00069	0.335
MOD_NEK2_1	61	66	PF00069	0.537
MOD_NEK2_1	630	635	PF00069	0.340
MOD_NEK2_1	660	665	PF00069	0.418
MOD_NEK2_1	770	775	PF00069	0.365
MOD_NEK2_1	860	865	PF00069	0.335
MOD_NEK2_1	882	887	PF00069	0.378
MOD_NEK2_1	94	99	PF00069	0.635
MOD_NEK2_2	1051	1056	PF00069	0.475
MOD_NEK2_2	717	722	PF00069	0.656
MOD_NEK2_2	996	1001	PF00069	0.422
MOD_PIKK_1	106	112	PF00454	0.721
MOD_PIKK_1	32	38	PF00454	0.584
MOD_PIKK_1	770	776	PF00454	0.347
MOD_PIKK_1	891	897	PF00454	0.354
MOD_PKA_1	577	583	PF00069	0.376
MOD_PKA_1	813	819	PF00069	0.273
MOD_PKA_1	905	911	PF00069	0.447
MOD_PKA_2	1010	1016	PF00069	0.435
MOD_PKA_2	106	112	PF00069	0.749
MOD_PKA_2	1086	1092	PF00069	0.617
MOD_PKA_2	1093	1099	PF00069	0.706
MOD_PKA_2	184	190	PF00069	0.774
MOD_PKA_2	313	319	PF00069	0.737
MOD_PKA_2	542	548	PF00069	0.335
MOD_PKA_2	577	583	PF00069	0.371
MOD_PKA_2	717	723	PF00069	0.727
MOD_PKA_2	812	818	PF00069	0.448
MOD_PKA_2	905	911	PF00069	0.360
MOD_PKA_2	994	1000	PF00069	0.568
MOD_Plk_1	164	170	PF00069	0.738
MOD_Plk_1	43	49	PF00069	0.518
MOD_Plk_1	462	468	PF00069	0.495
MOD_Plk_1	530	536	PF00069	0.428
MOD_Plk_1	550	556	PF00069	0.252
MOD_Plk_2-3	1100	1106	PF00069	0.698
MOD_Plk_2-3	731	737	PF00069	0.743
MOD_Plk_4	1040	1046	PF00069	0.591
MOD_Plk_4	1086	1092	PF00069	0.600
MOD_Plk_4	137	143	PF00069	0.689
MOD_Plk_4	167	173	PF00069	0.744
MOD_Plk_4	521	527	PF00069	0.369
MOD_Plk_4	530	536	PF00069	0.307
MOD_Plk_4	569	575	PF00069	0.378
MOD_Plk_4	61	67	PF00069	0.365
MOD_Plk_4	632	638	PF00069	0.335
MOD_Plk_4	717	723	PF00069	0.727
MOD_Plk_4	849	855	PF00069	0.351
MOD_Plk_4	888	894	PF00069	0.346
MOD_Plk_4	905	911	PF00069	0.221
MOD_ProDKin_1	1006	1012	PF00069	0.543
MOD_ProDKin_1	152	158	PF00069	0.774
MOD_ProDKin_1	206	212	PF00069	0.692
MOD_ProDKin_1	221	227	PF00069	0.559
MOD_ProDKin_1	231	237	PF00069	0.760
MOD_ProDKin_1	242	248	PF00069	0.782
MOD_ProDKin_1	376	382	PF00069	0.674
MOD_ProDKin_1	406	412	PF00069	0.605
MOD_ProDKin_1	419	425	PF00069	0.720
MOD_ProDKin_1	781	787	PF00069	0.335
MOD_ProDKin_1	952	958	PF00069	0.721
MOD_SUMO_for_1	172	175	PF00179	0.751
MOD_SUMO_for_1	275	278	PF00179	0.542
MOD_SUMO_rev_2	639	643	PF00179	0.501
TRG_DiLeu_BaEn_1	819	824	PF01217	0.335
TRG_DiLeu_BaEn_3	587	593	PF01217	0.447
TRG_DiLeu_BaLyEn_6	1018	1023	PF01217	0.664
TRG_DiLeu_BaLyEn_6	210	215	PF01217	0.664
TRG_DiLeu_BaLyEn_6	217	222	PF01217	0.554
TRG_DiLeu_BaLyEn_6	248	253	PF01217	0.640
TRG_DiLeu_BaLyEn_6	401	406	PF01217	0.731
TRG_ENDOCYTIC_2	1020	1023	PF00928	0.649
TRG_ENDOCYTIC_2	18	21	PF00928	0.449
TRG_ENDOCYTIC_2	458	461	PF00928	0.456
TRG_ENDOCYTIC_2	571	574	PF00928	0.335
TRG_ENDOCYTIC_2	626	629	PF00928	0.378
TRG_ENDOCYTIC_2	688	691	PF00928	0.512
TRG_ENDOCYTIC_2	752	755	PF00928	0.550
TRG_ENDOCYTIC_2	890	893	PF00928	0.335
TRG_ENDOCYTIC_2	917	920	PF00928	0.335
TRG_ENDOCYTIC_2	971	974	PF00928	0.570
TRG_ER_diArg_1	1058	1061	PF00400	0.455
TRG_ER_diArg_1	1091	1094	PF00400	0.654
TRG_ER_diArg_1	290	293	PF00400	0.578
TRG_ER_diArg_1	477	480	PF00400	0.335
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.732
TRG_Pf-PMV_PEXEL_1	265	269	PF00026	0.568
TRG_Pf-PMV_PEXEL_1	404	408	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	590	594	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	918	923	PF00026	0.340
TRG_Pf-PMV_PEXEL_1	924	928	PF00026	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM24	Leptomonas seymouri	64%	100%
A0A0S4JHE3	Bodo saltans	38%	100%
A0A1X0P056	Trypanosomatidae	52%	100%
A0A3S5IRW5	Trypanosoma rangeli	48%	100%
A4HH67	Leishmania braziliensis	83%	100%
A4I4B1	Leishmania infantum	99%	100%
C9ZKL6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9ADR1	Leishmania major	93%	100%
E9AM19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q580W5	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	52%	100%