LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H7K3_LEIDO
TriTrypDb:
LdBPK_283210.1 , LdCL_280037600 , LDHU3_28.4280
Length:
121

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7K3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7K3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 57 61 PF00656 0.605
CLV_PCSK_KEX2_1 42 44 PF00082 0.557
CLV_PCSK_KEX2_1 6 8 PF00082 0.579
CLV_PCSK_PC1ET2_1 42 44 PF00082 0.642
CLV_PCSK_PC1ET2_1 6 8 PF00082 0.579
CLV_PCSK_SKI1_1 3 7 PF00082 0.625
CLV_PCSK_SKI1_1 95 99 PF00082 0.395
DOC_CKS1_1 38 43 PF01111 0.550
DOC_MAPK_gen_1 76 84 PF00069 0.481
DOC_USP7_MATH_1 15 19 PF00917 0.611
DOC_USP7_MATH_1 33 37 PF00917 0.513
DOC_USP7_MATH_1 59 63 PF00917 0.617
DOC_USP7_MATH_1 93 97 PF00917 0.447
DOC_WW_Pin1_4 11 16 PF00397 0.655
DOC_WW_Pin1_4 21 26 PF00397 0.664
DOC_WW_Pin1_4 37 42 PF00397 0.653
LIG_BIR_II_1 1 5 PF00653 0.633
LIG_eIF4E_1 105 111 PF01652 0.505
LIG_FHA_1 33 39 PF00498 0.557
LIG_SH2_STAT5 105 108 PF00017 0.486
LIG_SH2_STAT5 49 52 PF00017 0.617
LIG_SH3_3 35 41 PF00018 0.591
LIG_WRC_WIRS_1 94 99 PF05994 0.412
MOD_CDK_SPK_2 37 42 PF00069 0.643
MOD_CDK_SPxK_1 37 43 PF00069 0.572
MOD_CK1_1 19 25 PF00069 0.707
MOD_CK1_1 63 69 PF00069 0.583
MOD_CK2_1 15 21 PF00069 0.679
MOD_GlcNHglycan 57 60 PF01048 0.690
MOD_GlcNHglycan 88 92 PF01048 0.512
MOD_GSK3_1 11 18 PF00069 0.648
MOD_GSK3_1 33 40 PF00069 0.611
MOD_GSK3_1 55 62 PF00069 0.687
MOD_PKA_2 19 25 PF00069 0.650
MOD_PKB_1 7 15 PF00069 0.547
MOD_Plk_1 59 65 PF00069 0.579
MOD_Plk_1 66 72 PF00069 0.553
MOD_Plk_4 66 72 PF00069 0.564
MOD_Plk_4 93 99 PF00069 0.413
MOD_ProDKin_1 11 17 PF00069 0.653
MOD_ProDKin_1 21 27 PF00069 0.663
MOD_ProDKin_1 37 43 PF00069 0.655
TRG_DiLeu_BaEn_1 79 84 PF01217 0.470
TRG_ER_diArg_1 7 10 PF00400 0.659
TRG_NLS_MonoExtC_3 5 11 PF00514 0.612
TRG_NLS_MonoExtN_4 3 10 PF00514 0.601

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5Y8 Leptomonas seymouri 49% 99%
A4HH00 Leishmania braziliensis 75% 100%
A4I432 Leishmania infantum 99% 100%
D0A8X6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS