DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

helicase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S5H7J4_LEIDO

TriTrypDb:

LdBPK_281730.1 , LdCL_280022200 , LDHU3_28.2260

Length:

1070

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0016020	membrane	2	7
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

Expansion

Sequence features

A0A3S5H7J4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7J4

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	1
GO:0006281	DNA repair	5	1
GO:0006289	nucleotide-excision repair	6	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0022402	cell cycle process	2	1
GO:0022414	reproductive process	1	1
GO:0033554	cellular response to stress	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1903046	meiotic cell cycle process	2	1
GO:1990918	double-strand break repair involved in meiotic recombination	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0016462	pyrophosphatase activity	5	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.523
CLV_C14_Caspase3-7	978	982	PF00656	0.723
CLV_NRD_NRD_1	126	128	PF00675	0.661
CLV_NRD_NRD_1	143	145	PF00675	0.461
CLV_NRD_NRD_1	170	172	PF00675	0.433
CLV_NRD_NRD_1	416	418	PF00675	0.694
CLV_NRD_NRD_1	453	455	PF00675	0.556
CLV_NRD_NRD_1	46	48	PF00675	0.629
CLV_NRD_NRD_1	60	62	PF00675	0.566
CLV_NRD_NRD_1	66	68	PF00675	0.668
CLV_NRD_NRD_1	74	76	PF00675	0.709
CLV_NRD_NRD_1	756	758	PF00675	0.293
CLV_NRD_NRD_1	902	904	PF00675	0.351
CLV_PCSK_FUR_1	414	418	PF00082	0.589
CLV_PCSK_FUR_1	58	62	PF00082	0.650
CLV_PCSK_KEX2_1	142	144	PF00082	0.586
CLV_PCSK_KEX2_1	170	172	PF00082	0.481
CLV_PCSK_KEX2_1	416	418	PF00082	0.665
CLV_PCSK_KEX2_1	420	422	PF00082	0.687
CLV_PCSK_KEX2_1	453	455	PF00082	0.589
CLV_PCSK_KEX2_1	46	48	PF00082	0.596
CLV_PCSK_KEX2_1	514	516	PF00082	0.247
CLV_PCSK_KEX2_1	60	62	PF00082	0.575
CLV_PCSK_KEX2_1	66	68	PF00082	0.669
CLV_PCSK_KEX2_1	74	76	PF00082	0.781
CLV_PCSK_KEX2_1	902	904	PF00082	0.332
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.741
CLV_PCSK_PC1ET2_1	46	48	PF00082	0.611
CLV_PCSK_PC1ET2_1	514	516	PF00082	0.247
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.759
CLV_PCSK_PC7_1	416	422	PF00082	0.656
CLV_PCSK_SKI1_1	1038	1042	PF00082	0.436
CLV_PCSK_SKI1_1	1050	1054	PF00082	0.433
CLV_PCSK_SKI1_1	143	147	PF00082	0.632
CLV_PCSK_SKI1_1	331	335	PF00082	0.508
CLV_PCSK_SKI1_1	515	519	PF00082	0.243
CLV_PCSK_SKI1_1	521	525	PF00082	0.260
CLV_PCSK_SKI1_1	552	556	PF00082	0.432
CLV_PCSK_SKI1_1	609	613	PF00082	0.260
CLV_PCSK_SKI1_1	729	733	PF00082	0.315
CLV_PCSK_SKI1_1	803	807	PF00082	0.315
CLV_PCSK_SKI1_1	902	906	PF00082	0.395
DEG_APCC_DBOX_1	330	338	PF00400	0.289
DEG_Nend_Nbox_1	1	3	PF02207	0.246
DEG_SCF_TRCP1_1	574	580	PF00400	0.642
DEG_SPOP_SBC_1	358	362	PF00917	0.467
DEG_SPOP_SBC_1	657	661	PF00917	0.582
DEG_SPOP_SBC_1	909	913	PF00917	0.660
DOC_CDC14_PxL_1	282	290	PF14671	0.335
DOC_CKS1_1	915	920	PF01111	0.653
DOC_CYCLIN_RxL_1	374	385	PF00134	0.386
DOC_CYCLIN_RxL_1	549	559	PF00134	0.604
DOC_CYCLIN_yCln2_LP_2	683	689	PF00134	0.528
DOC_CYCLIN_yCln2_LP_2	808	814	PF00134	0.535
DOC_MAPK_gen_1	127	135	PF00069	0.451
DOC_MAPK_gen_1	514	522	PF00069	0.457
DOC_MAPK_gen_1	726	734	PF00069	0.478
DOC_MAPK_gen_1	788	797	PF00069	0.437
DOC_MAPK_gen_1	849	859	PF00069	0.456
DOC_MAPK_MEF2A_6	331	338	PF00069	0.360
DOC_MAPK_MEF2A_6	514	522	PF00069	0.471
DOC_MAPK_MEF2A_6	803	812	PF00069	0.431
DOC_MAPK_NFAT4_5	331	339	PF00069	0.364
DOC_MAPK_NFAT4_5	515	523	PF00069	0.549
DOC_MAPK_NFAT4_5	803	811	PF00069	0.478
DOC_PP1_RVXF_1	270	277	PF00149	0.242
DOC_PP2B_LxvP_1	146	149	PF13499	0.381
DOC_PP2B_LxvP_1	672	675	PF13499	0.494
DOC_PP2B_LxvP_1	713	716	PF13499	0.446
DOC_PP2B_LxvP_1	808	811	PF13499	0.535
DOC_PP2B_LxvP_1	958	961	PF13499	0.657
DOC_PP4_FxxP_1	145	148	PF00568	0.415
DOC_PP4_FxxP_1	473	476	PF00568	0.417
DOC_PP4_FxxP_1	753	756	PF00568	0.456
DOC_USP7_MATH_1	1003	1007	PF00917	0.726
DOC_USP7_MATH_1	1044	1048	PF00917	0.706
DOC_USP7_MATH_1	343	347	PF00917	0.391
DOC_USP7_MATH_1	358	362	PF00917	0.469
DOC_USP7_MATH_1	479	483	PF00917	0.426
DOC_USP7_MATH_1	533	537	PF00917	0.520
DOC_USP7_MATH_1	657	661	PF00917	0.672
DOC_USP7_MATH_1	814	818	PF00917	0.442
DOC_USP7_MATH_1	916	920	PF00917	0.754
DOC_USP7_MATH_1	977	981	PF00917	0.677
DOC_USP7_MATH_1	984	988	PF00917	0.626
DOC_USP7_UBL2_3	68	72	PF12436	0.509
DOC_WW_Pin1_4	10	15	PF00397	0.276
DOC_WW_Pin1_4	1013	1018	PF00397	0.712
DOC_WW_Pin1_4	46	51	PF00397	0.367
DOC_WW_Pin1_4	615	620	PF00397	0.541
DOC_WW_Pin1_4	740	745	PF00397	0.474
DOC_WW_Pin1_4	910	915	PF00397	0.636
DOC_WW_Pin1_4	980	985	PF00397	0.778
LIG_14-3-3_CanoR_1	1004	1014	PF00244	0.666
LIG_14-3-3_CanoR_1	122	129	PF00244	0.490
LIG_14-3-3_CanoR_1	464	473	PF00244	0.477
LIG_14-3-3_CanoR_1	677	683	PF00244	0.567
LIG_14-3-3_CanoR_1	788	797	PF00244	0.460
LIG_14-3-3_CanoR_1	878	882	PF00244	0.606
LIG_14-3-3_CanoR_1	895	905	PF00244	0.596
LIG_14-3-3_CanoR_1	991	997	PF00244	0.736
LIG_Actin_WH2_2	148	165	PF00022	0.278
LIG_Actin_WH2_2	591	607	PF00022	0.508
LIG_Actin_WH2_2	689	706	PF00022	0.574
LIG_Actin_WH2_2	833	851	PF00022	0.491
LIG_APCC_ABBA_1	308	313	PF00400	0.242
LIG_APCC_ABBA_1	400	405	PF00400	0.308
LIG_BRCT_BRCA1_1	400	404	PF00533	0.273
LIG_BRCT_BRCA1_1	596	600	PF00533	0.457
LIG_CSL_BTD_1	964	967	PF09270	0.596
LIG_DCNL_PONY_1	1	4	PF03556	0.241
LIG_deltaCOP1_diTrp_1	109	118	PF00928	0.337
LIG_EH_1	500	504	PF12763	0.266
LIG_eIF4E_1	269	275	PF01652	0.225
LIG_eIF4E_1	287	293	PF01652	0.275
LIG_eIF4E_1	854	860	PF01652	0.439
LIG_EVH1_2	114	118	PF00568	0.372
LIG_FHA_1	1031	1037	PF00498	0.685
LIG_FHA_1	174	180	PF00498	0.337
LIG_FHA_1	202	208	PF00498	0.243
LIG_FHA_1	238	244	PF00498	0.229
LIG_FHA_1	29	35	PF00498	0.300
LIG_FHA_1	360	366	PF00498	0.514
LIG_FHA_1	578	584	PF00498	0.708
LIG_FHA_1	586	592	PF00498	0.504
LIG_FHA_1	667	673	PF00498	0.581
LIG_FHA_1	698	704	PF00498	0.589
LIG_FHA_1	726	732	PF00498	0.499
LIG_FHA_1	761	767	PF00498	0.501
LIG_FHA_1	778	784	PF00498	0.404
LIG_FHA_1	832	838	PF00498	0.498
LIG_FHA_1	910	916	PF00498	0.588
LIG_FHA_1	947	953	PF00498	0.738
LIG_FHA_2	101	107	PF00498	0.557
LIG_FHA_2	295	301	PF00498	0.335
LIG_FHA_2	383	389	PF00498	0.281
LIG_FHA_2	444	450	PF00498	0.391
LIG_FHA_2	700	706	PF00498	0.545
LIG_FHA_2	976	982	PF00498	0.748
LIG_Integrin_isoDGR_2	434	436	PF01839	0.640
LIG_Integrin_RGD_1	423	425	PF01839	0.646
LIG_LIR_Apic_2	108	114	PF02991	0.373
LIG_LIR_Apic_2	750	756	PF02991	0.525
LIG_LIR_Apic_2	861	867	PF02991	0.478
LIG_LIR_Gen_1	229	239	PF02991	0.275
LIG_LIR_Gen_1	368	376	PF02991	0.460
LIG_LIR_Gen_1	388	397	PF02991	0.187
LIG_LIR_Gen_1	597	607	PF02991	0.481
LIG_LIR_Nem_3	116	121	PF02991	0.339
LIG_LIR_Nem_3	229	234	PF02991	0.275
LIG_LIR_Nem_3	279	285	PF02991	0.275
LIG_LIR_Nem_3	388	393	PF02991	0.271
LIG_LIR_Nem_3	395	400	PF02991	0.258
LIG_LIR_Nem_3	401	406	PF02991	0.279
LIG_LIR_Nem_3	499	503	PF02991	0.325
LIG_LIR_Nem_3	597	603	PF02991	0.459
LIG_LIR_Nem_3	618	623	PF02991	0.580
LIG_LIR_Nem_3	632	637	PF02991	0.489
LIG_LIR_Nem_3	817	821	PF02991	0.478
LIG_LIR_Nem_3	851	857	PF02991	0.440
LIG_LYPXL_yS_3	285	288	PF13949	0.335
LIG_MLH1_MIPbox_1	400	404	PF16413	0.273
LIG_MYND_1	671	675	PF01753	0.557
LIG_NRBOX	519	525	PF00104	0.532
LIG_Pex14_1	901	905	PF04695	0.549
LIG_Pex14_2	117	121	PF04695	0.338
LIG_PTB_Apo_2	682	689	PF02174	0.584
LIG_REV1ctd_RIR_1	115	123	PF16727	0.367
LIG_SH2_CRK	490	494	PF00017	0.231
LIG_SH2_CRK	718	722	PF00017	0.522
LIG_SH2_CRK	854	858	PF00017	0.457
LIG_SH2_NCK_1	1027	1031	PF00017	0.638
LIG_SH2_NCK_1	277	281	PF00017	0.282
LIG_SH2_NCK_1	864	868	PF00017	0.498
LIG_SH2_SRC	277	280	PF00017	0.322
LIG_SH2_STAP1	1027	1031	PF00017	0.703
LIG_SH2_STAP1	648	652	PF00017	0.510
LIG_SH2_STAP1	832	836	PF00017	0.498
LIG_SH2_STAT3	56	59	PF00017	0.378
LIG_SH2_STAT3	767	770	PF00017	0.353
LIG_SH2_STAT5	154	157	PF00017	0.256
LIG_SH2_STAT5	190	193	PF00017	0.242
LIG_SH2_STAT5	287	290	PF00017	0.249
LIG_SH2_STAT5	56	59	PF00017	0.467
LIG_SH2_STAT5	602	605	PF00017	0.478
LIG_SH2_STAT5	832	835	PF00017	0.442
LIG_SH3_2	811	816	PF14604	0.439
LIG_SH3_3	1011	1017	PF00018	0.665
LIG_SH3_3	19	25	PF00018	0.312
LIG_SH3_3	639	645	PF00018	0.549
LIG_SH3_3	808	814	PF00018	0.439
LIG_SUMO_SIM_anti_2	730	735	PF11976	0.462
LIG_SUMO_SIM_par_1	17	23	PF11976	0.321
LIG_SUMO_SIM_par_1	385	391	PF11976	0.300
LIG_SUMO_SIM_par_1	856	862	PF11976	0.431
LIG_TRAF2_1	1058	1061	PF00917	0.760
LIG_TRFH_1	287	291	PF08558	0.231
LIG_TYR_ITIM	275	280	PF00017	0.272
LIG_UBA3_1	519	526	PF00899	0.510
LIG_WRC_WIRS_1	389	394	PF05994	0.315
MOD_CDC14_SPxK_1	983	986	PF00782	0.641
MOD_CDK_SPK_2	46	51	PF00069	0.447
MOD_CDK_SPxK_1	980	986	PF00069	0.647
MOD_CK1_1	1055	1061	PF00069	0.700
MOD_CK1_1	237	243	PF00069	0.235
MOD_CK1_1	357	363	PF00069	0.518
MOD_CK1_1	659	665	PF00069	0.680
MOD_CK1_1	980	986	PF00069	0.774
MOD_CK2_1	100	106	PF00069	0.544
MOD_CK2_1	1055	1061	PF00069	0.736
MOD_CK2_1	294	300	PF00069	0.335
MOD_CK2_1	336	342	PF00069	0.294
MOD_CK2_1	382	388	PF00069	0.291
MOD_CK2_1	443	449	PF00069	0.386
MOD_CK2_1	46	52	PF00069	0.370
MOD_CK2_1	545	551	PF00069	0.748
MOD_CK2_1	699	705	PF00069	0.587
MOD_Cter_Amidation	417	420	PF01082	0.597
MOD_Cter_Amidation	72	75	PF01082	0.740
MOD_GlcNHglycan	10	13	PF01048	0.595
MOD_GlcNHglycan	1005	1008	PF01048	0.501
MOD_GlcNHglycan	1054	1058	PF01048	0.492
MOD_GlcNHglycan	176	179	PF01048	0.439
MOD_GlcNHglycan	236	239	PF01048	0.506
MOD_GlcNHglycan	356	359	PF01048	0.706
MOD_GlcNHglycan	535	538	PF01048	0.379
MOD_GlcNHglycan	545	548	PF01048	0.553
MOD_GlcNHglycan	558	561	PF01048	0.479
MOD_GlcNHglycan	574	577	PF01048	0.448
MOD_GlcNHglycan	613	616	PF01048	0.263
MOD_GlcNHglycan	62	65	PF01048	0.685
MOD_GlcNHglycan	705	709	PF01048	0.320
MOD_GlcNHglycan	826	829	PF01048	0.231
MOD_GlcNHglycan	918	921	PF01048	0.499
MOD_GlcNHglycan	961	964	PF01048	0.490
MOD_GlcNHglycan	986	989	PF01048	0.496
MOD_GSK3_1	1026	1033	PF00069	0.650
MOD_GSK3_1	105	112	PF00069	0.487
MOD_GSK3_1	354	361	PF00069	0.509
MOD_GSK3_1	388	395	PF00069	0.323
MOD_GSK3_1	543	550	PF00069	0.704
MOD_GSK3_1	594	601	PF00069	0.565
MOD_GSK3_1	611	618	PF00069	0.374
MOD_GSK3_1	629	636	PF00069	0.451
MOD_GSK3_1	656	663	PF00069	0.612
MOD_GSK3_1	699	706	PF00069	0.516
MOD_GSK3_1	826	833	PF00069	0.407
MOD_GSK3_1	910	917	PF00069	0.694
MOD_GSK3_1	938	945	PF00069	0.641
MOD_GSK3_1	975	982	PF00069	0.751
MOD_LATS_1	120	126	PF00433	0.423
MOD_N-GLC_1	201	206	PF02516	0.481
MOD_N-GLC_1	770	775	PF02516	0.342
MOD_N-GLC_2	281	283	PF02516	0.528
MOD_NEK2_1	1018	1023	PF00069	0.643
MOD_NEK2_1	1026	1031	PF00069	0.638
MOD_NEK2_1	1052	1057	PF00069	0.747
MOD_NEK2_1	234	239	PF00069	0.298
MOD_NEK2_1	258	263	PF00069	0.335
MOD_NEK2_1	34	39	PF00069	0.311
MOD_NEK2_1	392	397	PF00069	0.287
MOD_NEK2_1	443	448	PF00069	0.378
MOD_NEK2_1	496	501	PF00069	0.278
MOD_NEK2_1	503	508	PF00069	0.266
MOD_NEK2_1	543	548	PF00069	0.672
MOD_NEK2_1	594	599	PF00069	0.468
MOD_NEK2_1	603	608	PF00069	0.521
MOD_NEK2_1	676	681	PF00069	0.557
MOD_NEK2_1	688	693	PF00069	0.515
MOD_NEK2_1	699	704	PF00069	0.505
MOD_NEK2_1	782	787	PF00069	0.518
MOD_NEK2_1	894	899	PF00069	0.526
MOD_NEK2_1	908	913	PF00069	0.589
MOD_NEK2_1	942	947	PF00069	0.709
MOD_NEK2_1	975	980	PF00069	0.812
MOD_NEK2_1	992	997	PF00069	0.715
MOD_NEK2_2	509	514	PF00069	0.210
MOD_PIKK_1	122	128	PF00454	0.520
MOD_PIKK_1	135	141	PF00454	0.431
MOD_PIKK_1	443	449	PF00454	0.451
MOD_PIKK_1	643	649	PF00454	0.610
MOD_PIKK_1	666	672	PF00454	0.725
MOD_PIKK_1	697	703	PF00454	0.552
MOD_PIKK_1	747	753	PF00454	0.490
MOD_PIKK_1	770	776	PF00454	0.545
MOD_PIKK_1	896	902	PF00454	0.472
MOD_PKA_1	60	66	PF00069	0.556
MOD_PKA_2	1003	1009	PF00069	0.737
MOD_PKA_2	60	66	PF00069	0.561
MOD_PKA_2	676	682	PF00069	0.593
MOD_PKA_2	703	709	PF00069	0.513
MOD_PKA_2	848	854	PF00069	0.413
MOD_PKA_2	871	877	PF00069	0.474
MOD_PKA_2	894	900	PF00069	0.618
MOD_PKB_1	58	66	PF00069	0.379
MOD_PKB_1	944	952	PF00069	0.741
MOD_Plk_1	201	207	PF00069	0.281
MOD_Plk_1	550	556	PF00069	0.718
MOD_Plk_1	629	635	PF00069	0.536
MOD_Plk_1	883	889	PF00069	0.574
MOD_Plk_2-3	100	106	PF00069	0.441
MOD_Plk_2-3	323	329	PF00069	0.242
MOD_Plk_4	113	119	PF00069	0.381
MOD_Plk_4	148	154	PF00069	0.277
MOD_Plk_4	34	40	PF00069	0.332
MOD_Plk_4	392	398	PF00069	0.317
MOD_Plk_4	629	635	PF00069	0.536
MOD_ProDKin_1	10	16	PF00069	0.277
MOD_ProDKin_1	1013	1019	PF00069	0.708
MOD_ProDKin_1	46	52	PF00069	0.368
MOD_ProDKin_1	615	621	PF00069	0.547
MOD_ProDKin_1	740	746	PF00069	0.474
MOD_ProDKin_1	910	916	PF00069	0.637
MOD_ProDKin_1	980	986	PF00069	0.779
MOD_SUMO_rev_2	290	299	PF00179	0.225
TRG_DiLeu_BaEn_2	387	393	PF01217	0.315
TRG_DiLeu_BaLyEn_6	288	293	PF01217	0.242
TRG_DiLeu_BaLyEn_6	668	673	PF01217	0.681
TRG_ENDOCYTIC_2	231	234	PF00928	0.256
TRG_ENDOCYTIC_2	277	280	PF00928	0.269
TRG_ENDOCYTIC_2	285	288	PF00928	0.263
TRG_ENDOCYTIC_2	490	493	PF00928	0.231
TRG_ENDOCYTIC_2	718	721	PF00928	0.442
TRG_ENDOCYTIC_2	854	857	PF00928	0.439
TRG_ER_diArg_1	141	144	PF00400	0.363
TRG_ER_diArg_1	169	171	PF00400	0.298
TRG_ER_diArg_1	452	454	PF00400	0.391
TRG_ER_diArg_1	463	466	PF00400	0.445
TRG_ER_diArg_1	57	60	PF00400	0.398
TRG_ER_diArg_1	901	903	PF00400	0.512
TRG_ER_diArg_1	944	947	PF00400	0.745
TRG_NES_CRM1_1	249	259	PF08389	0.303
TRG_NES_CRM1_1	340	354	PF08389	0.392
TRG_NES_CRM1_1	398	412	PF08389	0.296
TRG_NES_CRM1_1	799	813	PF08389	0.439
TRG_NLS_MonoExtC_3	126	132	PF00514	0.397
TRG_NLS_MonoExtC_3	418	423	PF00514	0.478
TRG_NLS_MonoExtC_3	45	50	PF00514	0.466
TRG_NLS_MonoExtN_4	416	423	PF00514	0.467
TRG_Pf-PMV_PEXEL_1	1024	1028	PF00026	0.396
TRG_Pf-PMV_PEXEL_1	3	7	PF00026	0.523
TRG_Pf-PMV_PEXEL_1	521	525	PF00026	0.321
TRG_Pf-PMV_PEXEL_1	625	630	PF00026	0.337

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8F0	Leptomonas seymouri	56%	84%
A0A0S4IQT3	Bodo saltans	38%	97%
A0A1X0NRE3	Trypanosomatidae	42%	100%
A0A3R7P0G4	Trypanosoma rangeli	43%	100%
A4HGL3	Leishmania braziliensis	80%	100%
A4I3N9	Leishmania infantum	99%	100%
D0A8C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9AZY0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q8A5	Leishmania major	92%	100%
V5BAP9	Trypanosoma cruzi	42%	100%