Retinoic acid induced 16-like protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Retinoic acid induced 16-like protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H7H7_LEIDO

TriTrypDb:

LdBPK_271040.1 , LdCL_270016900 , LDHU3_27.1660

Length:

986

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7H7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7H7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	180	184	PF00656	0.602
CLV_C14_Caspase3-7	342	346	PF00656	0.448
CLV_C14_Caspase3-7	842	846	PF00656	0.569
CLV_NRD_NRD_1	301	303	PF00675	0.534
CLV_NRD_NRD_1	412	414	PF00675	0.539
CLV_NRD_NRD_1	557	559	PF00675	0.565
CLV_NRD_NRD_1	683	685	PF00675	0.665
CLV_NRD_NRD_1	867	869	PF00675	0.714
CLV_NRD_NRD_1	893	895	PF00675	0.519
CLV_PCSK_KEX2_1	412	414	PF00082	0.467
CLV_PCSK_KEX2_1	847	849	PF00082	0.583
CLV_PCSK_KEX2_1	893	895	PF00082	0.635
CLV_PCSK_PC1ET2_1	847	849	PF00082	0.583
CLV_PCSK_SKI1_1	113	117	PF00082	0.611
CLV_PCSK_SKI1_1	194	198	PF00082	0.490
CLV_PCSK_SKI1_1	387	391	PF00082	0.524
CLV_PCSK_SKI1_1	417	421	PF00082	0.433
CLV_PCSK_SKI1_1	550	554	PF00082	0.411
CLV_PCSK_SKI1_1	669	673	PF00082	0.616
CLV_PCSK_SKI1_1	859	863	PF00082	0.594
CLV_PCSK_SKI1_1	868	872	PF00082	0.678
CLV_PCSK_SKI1_1	877	881	PF00082	0.546
DEG_APCC_DBOX_1	386	394	PF00400	0.547
DEG_APCC_DBOX_1	416	424	PF00400	0.447
DEG_APCC_DBOX_1	452	460	PF00400	0.415
DEG_SCF_FBW7_1	925	931	PF00400	0.760
DEG_SCF_TRCP1_1	695	701	PF00400	0.628
DEG_SPOP_SBC_1	318	322	PF00917	0.768
DEG_SPOP_SBC_1	38	42	PF00917	0.759
DEG_SPOP_SBC_1	774	778	PF00917	0.628
DEG_SPOP_SBC_1	887	891	PF00917	0.774
DOC_CDC14_PxL_1	368	376	PF14671	0.424
DOC_CDC14_PxL_1	616	624	PF14671	0.469
DOC_CKS1_1	925	930	PF01111	0.761
DOC_CYCLIN_RxL_1	191	200	PF00134	0.518
DOC_CYCLIN_RxL_1	384	394	PF00134	0.565
DOC_CYCLIN_RxL_1	494	505	PF00134	0.465
DOC_CYCLIN_RxL_1	545	556	PF00134	0.421
DOC_CYCLIN_yClb5_NLxxxL_5	387	393	PF00134	0.476
DOC_MAPK_gen_1	567	575	PF00069	0.452
DOC_MAPK_gen_1	748	758	PF00069	0.646
DOC_MAPK_gen_1	893	900	PF00069	0.585
DOC_MAPK_JIP1_4	289	295	PF00069	0.571
DOC_MAPK_MEF2A_6	289	297	PF00069	0.563
DOC_MAPK_MEF2A_6	893	902	PF00069	0.576
DOC_MAPK_RevD_3	835	848	PF00069	0.590
DOC_PP1_RVXF_1	543	549	PF00149	0.549
DOC_PP2B_LxvP_1	187	190	PF13499	0.613
DOC_PP2B_LxvP_1	293	296	PF13499	0.523
DOC_PP4_FxxP_1	130	133	PF00568	0.740
DOC_PP4_MxPP_1	771	774	PF00568	0.634
DOC_USP7_MATH_1	133	137	PF00917	0.708
DOC_USP7_MATH_1	144	148	PF00917	0.744
DOC_USP7_MATH_1	169	173	PF00917	0.771
DOC_USP7_MATH_1	17	21	PF00917	0.701
DOC_USP7_MATH_1	23	27	PF00917	0.682
DOC_USP7_MATH_1	39	43	PF00917	0.744
DOC_USP7_MATH_1	422	426	PF00917	0.511
DOC_USP7_MATH_1	427	431	PF00917	0.549
DOC_USP7_MATH_1	601	605	PF00917	0.697
DOC_USP7_MATH_1	609	613	PF00917	0.523
DOC_USP7_MATH_1	774	778	PF00917	0.706
DOC_USP7_MATH_1	885	889	PF00917	0.765
DOC_USP7_MATH_1	928	932	PF00917	0.796
DOC_WW_Pin1_4	139	144	PF00397	0.725
DOC_WW_Pin1_4	165	170	PF00397	0.784
DOC_WW_Pin1_4	323	328	PF00397	0.768
DOC_WW_Pin1_4	514	519	PF00397	0.492
DOC_WW_Pin1_4	54	59	PF00397	0.675
DOC_WW_Pin1_4	707	712	PF00397	0.622
DOC_WW_Pin1_4	797	802	PF00397	0.561
DOC_WW_Pin1_4	813	818	PF00397	0.474
DOC_WW_Pin1_4	871	876	PF00397	0.746
DOC_WW_Pin1_4	921	926	PF00397	0.796
LIG_14-3-3_CanoR_1	281	286	PF00244	0.623
LIG_14-3-3_CanoR_1	317	327	PF00244	0.739
LIG_14-3-3_CanoR_1	417	426	PF00244	0.451
LIG_14-3-3_CanoR_1	453	457	PF00244	0.433
LIG_14-3-3_CanoR_1	480	486	PF00244	0.411
LIG_14-3-3_CanoR_1	645	653	PF00244	0.512
LIG_14-3-3_CanoR_1	766	774	PF00244	0.634
LIG_14-3-3_CanoR_1	838	844	PF00244	0.514
LIG_14-3-3_CanoR_1	868	876	PF00244	0.737
LIG_14-3-3_CanoR_1	88	92	PF00244	0.628
LIG_Actin_WH2_2	656	671	PF00022	0.593
LIG_AP2alpha_2	431	433	PF02296	0.536
LIG_BIR_II_1	1	5	PF00653	0.733
LIG_BRCT_BRCA1_1	126	130	PF00533	0.702
LIG_BRCT_BRCA1_1	898	902	PF00533	0.642
LIG_Clathr_ClatBox_1	390	394	PF01394	0.420
LIG_Clathr_ClatBox_1	749	753	PF01394	0.529
LIG_deltaCOP1_diTrp_1	67	76	PF00928	0.443
LIG_DLG_GKlike_1	281	288	PF00625	0.386
LIG_EH1_1	817	825	PF00400	0.595
LIG_eIF4E_1	818	824	PF01652	0.633
LIG_FAT_LD_1	393	401	PF03623	0.363
LIG_FHA_1	327	333	PF00498	0.645
LIG_FHA_1	353	359	PF00498	0.489
LIG_FHA_1	38	44	PF00498	0.673
LIG_FHA_1	452	458	PF00498	0.446
LIG_FHA_1	46	52	PF00498	0.652
LIG_FHA_1	468	474	PF00498	0.449
LIG_FHA_1	493	499	PF00498	0.550
LIG_FHA_1	585	591	PF00498	0.699
LIG_FHA_1	613	619	PF00498	0.515
LIG_FHA_1	650	656	PF00498	0.465
LIG_FHA_1	784	790	PF00498	0.679
LIG_FHA_1	801	807	PF00498	0.569
LIG_FHA_1	871	877	PF00498	0.725
LIG_FHA_2	361	367	PF00498	0.480
LIG_FHA_2	656	662	PF00498	0.623
LIG_FHA_2	82	88	PF00498	0.646
LIG_FHA_2	840	846	PF00498	0.516
LIG_GBD_Chelix_1	529	537	PF00786	0.550
LIG_LIR_Apic_2	127	133	PF02991	0.569
LIG_LIR_Apic_2	615	620	PF02991	0.592
LIG_LIR_Gen_1	335	345	PF02991	0.681
LIG_LIR_Gen_1	355	365	PF02991	0.425
LIG_LIR_Gen_1	67	76	PF02991	0.445
LIG_LIR_Nem_3	335	341	PF02991	0.677
LIG_LIR_Nem_3	355	360	PF02991	0.429
LIG_LIR_Nem_3	611	617	PF02991	0.454
LIG_LIR_Nem_3	67	72	PF02991	0.420
LIG_LIR_Nem_3	74	79	PF02991	0.438
LIG_NRBOX	105	111	PF00104	0.559
LIG_NRBOX	259	265	PF00104	0.499
LIG_NRBOX	388	394	PF00104	0.443
LIG_NRBOX	720	726	PF00104	0.568
LIG_NRBOX	745	751	PF00104	0.523
LIG_NRBOX	839	845	PF00104	0.651
LIG_Pex14_2	130	134	PF04695	0.723
LIG_Rb_pABgroove_1	898	906	PF01858	0.588
LIG_SH2_CRK	193	197	PF00017	0.509
LIG_SH2_CRK	904	908	PF00017	0.581
LIG_SH2_CRK	954	958	PF00017	0.647
LIG_SH2_CRK	972	976	PF00017	0.526
LIG_SH2_PTP2	617	620	PF00017	0.472
LIG_SH2_SRC	961	964	PF00017	0.581
LIG_SH2_SRC	965	968	PF00017	0.540
LIG_SH2_STAP1	571	575	PF00017	0.674
LIG_SH2_STAP1	904	908	PF00017	0.503
LIG_SH2_STAP1	954	958	PF00017	0.603
LIG_SH2_STAT3	243	246	PF00017	0.517
LIG_SH2_STAT5	128	131	PF00017	0.686
LIG_SH2_STAT5	399	402	PF00017	0.474
LIG_SH2_STAT5	474	477	PF00017	0.448
LIG_SH2_STAT5	617	620	PF00017	0.472
LIG_SH2_STAT5	75	78	PF00017	0.432
LIG_SH2_STAT5	818	821	PF00017	0.645
LIG_SH2_STAT5	841	844	PF00017	0.502
LIG_SH2_STAT5	961	964	PF00017	0.609
LIG_SH2_STAT5	965	968	PF00017	0.624
LIG_SH2_STAT5	972	975	PF00017	0.656
LIG_SH2_STAT5	981	984	PF00017	0.430
LIG_SH3_3	137	143	PF00018	0.739
LIG_SH3_3	200	206	PF00018	0.734
LIG_SH3_3	5	11	PF00018	0.573
LIG_SH3_3	572	578	PF00018	0.649
LIG_SH3_3	603	609	PF00018	0.652
LIG_SH3_3	895	901	PF00018	0.664
LIG_SH3_3	922	928	PF00018	0.759
LIG_SUMO_SIM_anti_2	60	67	PF11976	0.464
LIG_SUMO_SIM_anti_2	652	658	PF11976	0.581
LIG_SUMO_SIM_anti_2	830	836	PF11976	0.656
LIG_SUMO_SIM_par_1	388	394	PF11976	0.346
LIG_SUMO_SIM_par_1	652	658	PF11976	0.558
LIG_SUMO_SIM_par_1	672	678	PF11976	0.350
LIG_SUMO_SIM_par_1	894	899	PF11976	0.656
LIG_TRAF2_1	405	408	PF00917	0.587
LIG_TRAF2_1	439	442	PF00917	0.467
LIG_TYR_ITIM	839	844	PF00017	0.603
LIG_TYR_ITIM	952	957	PF00017	0.641
LIG_TYR_ITIM	970	975	PF00017	0.527
LIG_TYR_ITIM	979	984	PF00017	0.672
LIG_UBA3_1	237	245	PF00899	0.440
LIG_UBA3_1	297	303	PF00899	0.470
LIG_UBA3_1	456	461	PF00899	0.453
LIG_UBA3_1	498	504	PF00899	0.544
LIG_UBA3_1	767	772	PF00899	0.720
LIG_UBA3_1	91	100	PF00899	0.602
LIG_UBA3_1	979	983	PF00899	0.630
LIG_WRC_WIRS_1	610	615	PF05994	0.502
LIG_WW_1	190	193	PF00397	0.442
MOD_CDC14_SPxK_1	874	877	PF00782	0.760
MOD_CDK_SPxK_1	871	877	PF00069	0.748
MOD_CDK_SPxxK_3	871	878	PF00069	0.751
MOD_CK1_1	172	178	PF00069	0.744
MOD_CK1_1	326	332	PF00069	0.626
MOD_CK1_1	517	523	PF00069	0.503
MOD_CK1_1	57	63	PF00069	0.547
MOD_CK1_1	612	618	PF00069	0.485
MOD_CK1_1	701	707	PF00069	0.683
MOD_CK1_1	723	729	PF00069	0.678
MOD_CK1_1	776	782	PF00069	0.646
MOD_CK1_1	800	806	PF00069	0.661
MOD_CK1_1	816	822	PF00069	0.513
MOD_CK1_1	883	889	PF00069	0.686
MOD_CK1_1	924	930	PF00069	0.731
MOD_CK1_1	932	938	PF00069	0.506
MOD_CK2_1	139	145	PF00069	0.713
MOD_CK2_1	360	366	PF00069	0.436
MOD_CK2_1	402	408	PF00069	0.571
MOD_CK2_1	601	607	PF00069	0.654
MOD_CK2_1	655	661	PF00069	0.584
MOD_CK2_1	81	87	PF00069	0.641
MOD_CK2_1	930	936	PF00069	0.664
MOD_GlcNHglycan	137	140	PF01048	0.770
MOD_GlcNHglycan	169	172	PF01048	0.692
MOD_GlcNHglycan	18	22	PF01048	0.613
MOD_GlcNHglycan	272	276	PF01048	0.643
MOD_GlcNHglycan	290	293	PF01048	0.552
MOD_GlcNHglycan	323	326	PF01048	0.790
MOD_GlcNHglycan	34	37	PF01048	0.745
MOD_GlcNHglycan	420	423	PF01048	0.531
MOD_GlcNHglycan	523	526	PF01048	0.446
MOD_GlcNHglycan	539	542	PF01048	0.469
MOD_GlcNHglycan	560	563	PF01048	0.549
MOD_GlcNHglycan	582	585	PF01048	0.701
MOD_GlcNHglycan	646	649	PF01048	0.581
MOD_GlcNHglycan	695	698	PF01048	0.681
MOD_GlcNHglycan	700	703	PF01048	0.573
MOD_GlcNHglycan	706	709	PF01048	0.461
MOD_GlcNHglycan	725	728	PF01048	0.551
MOD_GlcNHglycan	768	771	PF01048	0.683
MOD_GlcNHglycan	884	888	PF01048	0.618
MOD_GlcNHglycan	932	935	PF01048	0.723
MOD_GlcNHglycan	936	940	PF01048	0.649
MOD_GSK3_1	135	142	PF00069	0.719
MOD_GSK3_1	160	167	PF00069	0.797
MOD_GSK3_1	169	176	PF00069	0.711
MOD_GSK3_1	23	30	PF00069	0.729
MOD_GSK3_1	316	323	PF00069	0.703
MOD_GSK3_1	326	333	PF00069	0.674
MOD_GSK3_1	398	405	PF00069	0.517
MOD_GSK3_1	418	425	PF00069	0.378
MOD_GSK3_1	451	458	PF00069	0.443
MOD_GSK3_1	484	491	PF00069	0.471
MOD_GSK3_1	517	524	PF00069	0.499
MOD_GSK3_1	580	587	PF00069	0.679
MOD_GSK3_1	608	615	PF00069	0.612
MOD_GSK3_1	640	647	PF00069	0.658
MOD_GSK3_1	719	726	PF00069	0.629
MOD_GSK3_1	773	780	PF00069	0.734
MOD_GSK3_1	796	803	PF00069	0.628
MOD_GSK3_1	812	819	PF00069	0.415
MOD_GSK3_1	839	846	PF00069	0.571
MOD_GSK3_1	883	890	PF00069	0.762
MOD_GSK3_1	924	931	PF00069	0.794
MOD_N-GLC_1	928	933	PF02516	0.715
MOD_NEK2_1	115	120	PF00069	0.608
MOD_NEK2_1	173	178	PF00069	0.755
MOD_NEK2_1	197	202	PF00069	0.590
MOD_NEK2_1	27	32	PF00069	0.716
MOD_NEK2_1	360	365	PF00069	0.431
MOD_NEK2_1	418	423	PF00069	0.526
MOD_NEK2_1	481	486	PF00069	0.479
MOD_NEK2_1	537	542	PF00069	0.467
MOD_NEK2_1	552	557	PF00069	0.421
MOD_NEK2_1	590	595	PF00069	0.714
MOD_NEK2_1	639	644	PF00069	0.639
MOD_NEK2_1	655	660	PF00069	0.359
MOD_NEK2_1	720	725	PF00069	0.657
MOD_NEK2_1	827	832	PF00069	0.490
MOD_NEK2_1	843	848	PF00069	0.532
MOD_NEK2_1	896	901	PF00069	0.582
MOD_NEK2_2	609	614	PF00069	0.590
MOD_PIKK_1	352	358	PF00454	0.498
MOD_PIKK_1	381	387	PF00454	0.679
MOD_PIKK_1	403	409	PF00454	0.593
MOD_PIKK_1	467	473	PF00454	0.501
MOD_PIKK_1	973	979	PF00454	0.646
MOD_PK_1	100	106	PF00069	0.473
MOD_PKA_1	302	308	PF00069	0.545
MOD_PKA_1	412	418	PF00069	0.478
MOD_PKA_1	558	564	PF00069	0.569
MOD_PKA_1	868	874	PF00069	0.642
MOD_PKA_1	877	883	PF00069	0.566
MOD_PKA_2	152	158	PF00069	0.806
MOD_PKA_2	288	294	PF00069	0.504
MOD_PKA_2	316	322	PF00069	0.782
MOD_PKA_2	412	418	PF00069	0.478
MOD_PKA_2	452	458	PF00069	0.416
MOD_PKA_2	644	650	PF00069	0.528
MOD_PKA_2	87	93	PF00069	0.638
MOD_PKB_1	764	772	PF00069	0.689
MOD_Plk_1	144	150	PF00069	0.607
MOD_Plk_1	271	277	PF00069	0.672
MOD_Plk_1	633	639	PF00069	0.663
MOD_Plk_1	86	92	PF00069	0.594
MOD_Plk_2-3	675	681	PF00069	0.646
MOD_Plk_2-3	94	100	PF00069	0.556
MOD_Plk_4	100	106	PF00069	0.461
MOD_Plk_4	124	130	PF00069	0.757
MOD_Plk_4	281	287	PF00069	0.485
MOD_Plk_4	344	350	PF00069	0.578
MOD_Plk_4	452	458	PF00069	0.471
MOD_Plk_4	481	487	PF00069	0.414
MOD_Plk_4	507	513	PF00069	0.428
MOD_Plk_4	57	63	PF00069	0.519
MOD_Plk_4	609	615	PF00069	0.452
MOD_Plk_4	634	640	PF00069	0.685
MOD_Plk_4	649	655	PF00069	0.405
MOD_Plk_4	720	726	PF00069	0.583
MOD_Plk_4	819	825	PF00069	0.468
MOD_Plk_4	839	845	PF00069	0.505
MOD_Plk_4	87	93	PF00069	0.637
MOD_ProDKin_1	139	145	PF00069	0.729
MOD_ProDKin_1	165	171	PF00069	0.782
MOD_ProDKin_1	323	329	PF00069	0.757
MOD_ProDKin_1	514	520	PF00069	0.496
MOD_ProDKin_1	54	60	PF00069	0.660
MOD_ProDKin_1	707	713	PF00069	0.621
MOD_ProDKin_1	797	803	PF00069	0.555
MOD_ProDKin_1	813	819	PF00069	0.474
MOD_ProDKin_1	871	877	PF00069	0.748
MOD_ProDKin_1	921	927	PF00069	0.798
MOD_SUMO_for_1	439	442	PF00179	0.467
MOD_SUMO_rev_2	629	635	PF00179	0.712
TRG_DiLeu_BaEn_1	386	391	PF01217	0.498
TRG_DiLeu_BaEn_1	634	639	PF01217	0.679
TRG_DiLeu_BaEn_1	87	92	PF01217	0.632
TRG_DiLeu_BaLyEn_6	259	264	PF01217	0.415
TRG_DiLeu_BaLyEn_6	293	298	PF01217	0.436
TRG_DiLeu_BaLyEn_6	494	499	PF01217	0.570
TRG_DiLeu_BaLyEn_6	510	515	PF01217	0.392
TRG_DiLeu_BaLyEn_6	539	544	PF01217	0.562
TRG_DiLeu_BaLyEn_6	745	750	PF01217	0.523
TRG_ENDOCYTIC_2	193	196	PF00928	0.432
TRG_ENDOCYTIC_2	571	574	PF00928	0.618
TRG_ENDOCYTIC_2	616	619	PF00928	0.446
TRG_ENDOCYTIC_2	841	844	PF00928	0.502
TRG_ENDOCYTIC_2	904	907	PF00928	0.476
TRG_ENDOCYTIC_2	954	957	PF00928	0.647
TRG_ENDOCYTIC_2	972	975	PF00928	0.528
TRG_ENDOCYTIC_2	981	984	PF00928	0.676
TRG_ER_diArg_1	761	764	PF00400	0.578
TRG_ER_diArg_1	893	895	PF00400	0.519
TRG_NES_CRM1_1	94	107	PF08389	0.573
TRG_Pf-PMV_PEXEL_1	194	199	PF00026	0.511
TRG_Pf-PMV_PEXEL_1	262	266	PF00026	0.442
TRG_Pf-PMV_PEXEL_1	49	54	PF00026	0.697
TRG_Pf-PMV_PEXEL_1	748	753	PF00026	0.536

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6X3	Leptomonas seymouri	51%	90%
A0A1X0P440	Trypanosomatidae	31%	96%
A0A3S5IQJ7	Trypanosoma rangeli	29%	100%
A4HFP1	Leishmania braziliensis	76%	99%
A4I2R7	Leishmania infantum	99%	100%
E9AD94	Leishmania major	92%	100%
E9AZ19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5BHP8	Trypanosoma cruzi	30%	100%