Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H7E5_LEIDO

TriTrypDb:

LdBPK_250980.1 , LdCL_250015100 , LDHU3_25.1250

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7E5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7E5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	150	154	PF00656	0.567
CLV_NRD_NRD_1	120	122	PF00675	0.566
CLV_NRD_NRD_1	156	158	PF00675	0.554
CLV_NRD_NRD_1	222	224	PF00675	0.707
CLV_NRD_NRD_1	269	271	PF00675	0.738
CLV_NRD_NRD_1	39	41	PF00675	0.436
CLV_PCSK_FUR_1	219	223	PF00082	0.597
CLV_PCSK_KEX2_1	120	122	PF00082	0.566
CLV_PCSK_KEX2_1	156	158	PF00082	0.554
CLV_PCSK_KEX2_1	221	223	PF00082	0.600
CLV_PCSK_KEX2_1	268	270	PF00082	0.644
CLV_PCSK_KEX2_1	39	41	PF00082	0.436
CLV_PCSK_PC7_1	264	270	PF00082	0.634
CLV_PCSK_SKI1_1	233	237	PF00082	0.600
CLV_PCSK_SKI1_1	39	43	PF00082	0.389
CLV_PCSK_SKI1_1	98	102	PF00082	0.430
DOC_PP1_RVXF_1	96	103	PF00149	0.501
DOC_PP4_FxxP_1	31	34	PF00568	0.478
DOC_USP7_MATH_1	111	115	PF00917	0.606
DOC_USP7_MATH_1	12	16	PF00917	0.702
DOC_USP7_MATH_1	148	152	PF00917	0.527
DOC_WW_Pin1_4	262	267	PF00397	0.591
DOC_WW_Pin1_4	268	273	PF00397	0.619
LIG_14-3-3_CanoR_1	137	143	PF00244	0.448
LIG_14-3-3_CanoR_1	231	236	PF00244	0.547
LIG_14-3-3_CanoR_1	60	65	PF00244	0.444
LIG_BIR_II_1	1	5	PF00653	0.534
LIG_BIR_III_4	116	120	PF00653	0.573
LIG_FHA_1	184	190	PF00498	0.469
LIG_FHA_1	211	217	PF00498	0.578
LIG_FHA_1	95	101	PF00498	0.431
LIG_FHA_2	174	180	PF00498	0.487
LIG_LIR_Apic_2	29	34	PF02991	0.471
LIG_LIR_Gen_1	58	69	PF02991	0.393
LIG_LIR_Gen_1	97	105	PF02991	0.471
LIG_LIR_Nem_3	58	64	PF02991	0.398
LIG_LIR_Nem_3	97	102	PF02991	0.432
LIG_NRBOX	190	196	PF00104	0.633
LIG_SH2_SRC	158	161	PF00017	0.533
LIG_SH2_STAT5	61	64	PF00017	0.435
LIG_SH2_STAT5	99	102	PF00017	0.538
LIG_SH3_3	53	59	PF00018	0.433
LIG_SUMO_SIM_par_1	18	24	PF11976	0.472
LIG_WRC_WIRS_1	61	66	PF05994	0.374
MOD_CDC14_SPxK_1	265	268	PF00782	0.625
MOD_CDK_SPxK_1	262	268	PF00069	0.630
MOD_CDK_SPxxK_3	262	269	PF00069	0.631
MOD_CK1_1	15	21	PF00069	0.528
MOD_CK1_1	210	216	PF00069	0.606
MOD_CK1_1	29	35	PF00069	0.583
MOD_CK1_1	65	71	PF00069	0.375
MOD_CK2_1	143	149	PF00069	0.518
MOD_CK2_1	173	179	PF00069	0.552
MOD_Cter_Amidation	118	121	PF01082	0.571
MOD_GlcNHglycan	13	17	PF01048	0.531
MOD_GlcNHglycan	149	153	PF01048	0.581
MOD_GlcNHglycan	170	173	PF01048	0.660
MOD_GlcNHglycan	2	5	PF01048	0.599
MOD_GlcNHglycan	254	257	PF01048	0.697
MOD_GlcNHglycan	28	31	PF01048	0.541
MOD_GlcNHglycan	64	67	PF01048	0.377
MOD_GlcNHglycan	8	11	PF01048	0.557
MOD_GSK3_1	138	145	PF00069	0.420
MOD_GSK3_1	148	155	PF00069	0.486
MOD_GSK3_1	206	213	PF00069	0.642
MOD_GSK3_1	60	67	PF00069	0.395
MOD_GSK3_1	8	15	PF00069	0.710
MOD_GSK3_1	90	97	PF00069	0.434
MOD_NEK2_1	105	110	PF00069	0.589
MOD_NEK2_1	168	173	PF00069	0.651
MOD_NEK2_1	21	26	PF00069	0.561
MOD_NEK2_1	64	69	PF00069	0.398
MOD_PIKK_1	207	213	PF00454	0.611
MOD_PKA_2	183	189	PF00069	0.491
MOD_PKA_2	59	65	PF00069	0.453
MOD_Plk_1	143	149	PF00069	0.518
MOD_Plk_4	138	144	PF00069	0.452
MOD_ProDKin_1	262	268	PF00069	0.592
TRG_DiLeu_BaLyEn_6	17	22	PF01217	0.443
TRG_DiLeu_BaLyEn_6	190	195	PF01217	0.491
TRG_DiLeu_BaLyEn_6	44	49	PF01217	0.416
TRG_ENDOCYTIC_2	61	64	PF00928	0.377
TRG_ENDOCYTIC_2	99	102	PF00928	0.429
TRG_ER_diArg_1	120	123	PF00400	0.564
TRG_ER_diArg_1	156	158	PF00400	0.554
TRG_ER_diArg_1	219	222	PF00400	0.594
TRG_ER_diArg_1	267	270	PF00400	0.643

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILU1	Leptomonas seymouri	38%	69%
A4I1D6	Leishmania infantum	99%	100%