LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Beta galactofuranosyl transferase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Beta galactofuranosyl transferase
Gene product:
beta galactofuranosyl transferase
Species:
Leishmania donovani
UniProt:
A0A3S5H7D9_LEIDO
TriTrypDb:
LdBPK_250010.1 * , LdCL_250005000 , LDHU3_25.0020
Length:
434

Annotations

LeishMANIAdb annotations

A large family of glycosyltransferases expanded in parazitic kinetoplastids (and even more in T cruzi). Localization: ER (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 37
NetGPI no yes: 0, no: 37
Cellular components
Term Name Level Count
GO:0016020 membrane 2 14
GO:0110165 cellular anatomical entity 1 14
GO:0005886 plasma membrane 3 1

Expansion

Sequence features

A0A3S5H7D9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7D9

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 38
GO:0016740 transferase activity 2 38
GO:0016757 glycosyltransferase activity 3 4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_MEL_PAP_1 15 21 PF00089 0.175
CLV_NRD_NRD_1 11 13 PF00675 0.468
CLV_NRD_NRD_1 204 206 PF00675 0.653
CLV_NRD_NRD_1 365 367 PF00675 0.497
CLV_NRD_NRD_1 403 405 PF00675 0.542
CLV_PCSK_FUR_1 202 206 PF00082 0.458
CLV_PCSK_KEX2_1 10 12 PF00082 0.479
CLV_PCSK_KEX2_1 204 206 PF00082 0.653
CLV_PCSK_KEX2_1 365 367 PF00082 0.520
CLV_PCSK_KEX2_1 402 404 PF00082 0.541
CLV_PCSK_PC7_1 361 367 PF00082 0.566
CLV_PCSK_SKI1_1 120 124 PF00082 0.557
CLV_PCSK_SKI1_1 158 162 PF00082 0.444
CLV_PCSK_SKI1_1 224 228 PF00082 0.576
CLV_PCSK_SKI1_1 337 341 PF00082 0.656
CLV_PCSK_SKI1_1 365 369 PF00082 0.538
CLV_PCSK_SKI1_1 95 99 PF00082 0.536
DEG_APCC_DBOX_1 119 127 PF00400 0.350
DEG_APCC_DBOX_1 17 25 PF00400 0.492
DOC_CYCLIN_RxL_1 117 124 PF00134 0.421
DOC_CYCLIN_yCln2_LP_2 427 433 PF00134 0.252
DOC_MAPK_DCC_7 79 89 PF00069 0.340
DOC_MAPK_gen_1 10 19 PF00069 0.644
DOC_MAPK_gen_1 417 426 PF00069 0.444
DOC_MAPK_MEF2A_6 10 19 PF00069 0.612
DOC_MAPK_MEF2A_6 79 87 PF00069 0.338
DOC_PP1_RVXF_1 317 324 PF00149 0.321
DOC_PP1_RVXF_1 423 430 PF00149 0.257
DOC_PP4_FxxP_1 314 317 PF00568 0.356
DOC_PP4_FxxP_1 360 363 PF00568 0.192
DOC_PP4_MxPP_1 1 4 PF00568 0.529
DOC_USP7_MATH_1 118 122 PF00917 0.411
DOC_USP7_MATH_1 226 230 PF00917 0.399
DOC_WW_Pin1_4 46 51 PF00397 0.290
LIG_14-3-3_CanoR_1 117 123 PF00244 0.413
LIG_14-3-3_CanoR_1 228 235 PF00244 0.273
LIG_14-3-3_CanoR_1 243 248 PF00244 0.411
LIG_14-3-3_CanoR_1 69 73 PF00244 0.393
LIG_Actin_WH2_2 203 220 PF00022 0.271
LIG_APCC_ABBA_1 374 379 PF00400 0.290
LIG_BIR_II_1 1 5 PF00653 0.744
LIG_BIR_III_1 1 5 PF00653 0.526
LIG_BIR_III_3 1 5 PF00653 0.526
LIG_BRCT_BRCA1_1 348 352 PF00533 0.385
LIG_eIF4E_1 133 139 PF01652 0.352
LIG_eIF4E_1 22 28 PF01652 0.221
LIG_FHA_1 257 263 PF00498 0.376
LIG_FHA_1 271 277 PF00498 0.350
LIG_FHA_1 388 394 PF00498 0.393
LIG_FHA_2 172 178 PF00498 0.216
LIG_FHA_2 43 49 PF00498 0.416
LIG_FXI_DFP_1 426 430 PF00024 0.431
LIG_HCF-1_HBM_1 298 301 PF13415 0.379
LIG_LIR_Gen_1 106 115 PF02991 0.327
LIG_LIR_Gen_1 60 70 PF02991 0.359
LIG_LIR_Gen_1 88 98 PF02991 0.311
LIG_LIR_Nem_3 106 110 PF02991 0.334
LIG_LIR_Nem_3 258 263 PF02991 0.264
LIG_LIR_Nem_3 289 295 PF02991 0.286
LIG_LIR_Nem_3 418 422 PF02991 0.259
LIG_LIR_Nem_3 60 66 PF02991 0.352
LIG_LIR_Nem_3 88 94 PF02991 0.338
LIG_NRBOX 20 26 PF00104 0.365
LIG_Pex14_2 270 274 PF04695 0.227
LIG_PTB_Apo_2 110 117 PF02174 0.351
LIG_PTB_Apo_2 219 226 PF02174 0.241
LIG_PTB_Apo_2 339 346 PF02174 0.276
LIG_PTB_Phospho_1 339 345 PF10480 0.271
LIG_SH2_CRK 22 26 PF00017 0.432
LIG_SH2_PTP2 30 33 PF00017 0.219
LIG_SH2_PTP2 82 85 PF00017 0.213
LIG_SH2_SRC 91 94 PF00017 0.221
LIG_SH2_STAP1 149 153 PF00017 0.232
LIG_SH2_STAP1 22 26 PF00017 0.209
LIG_SH2_STAP1 422 426 PF00017 0.256
LIG_SH2_STAT3 133 136 PF00017 0.199
LIG_SH2_STAT3 345 348 PF00017 0.392
LIG_SH2_STAT3 72 75 PF00017 0.268
LIG_SH2_STAT5 107 110 PF00017 0.342
LIG_SH2_STAT5 133 136 PF00017 0.327
LIG_SH2_STAT5 22 25 PF00017 0.368
LIG_SH2_STAT5 264 267 PF00017 0.412
LIG_SH2_STAT5 30 33 PF00017 0.335
LIG_SH2_STAT5 301 304 PF00017 0.296
LIG_SH2_STAT5 313 316 PF00017 0.300
LIG_SH2_STAT5 345 348 PF00017 0.401
LIG_SH2_STAT5 82 85 PF00017 0.230
LIG_SH3_3 217 223 PF00018 0.369
LIG_SH3_3 427 433 PF00018 0.252
LIG_SH3_3 80 86 PF00018 0.379
LIG_TRAF2_1 248 251 PF00917 0.266
LIG_TRFH_1 82 86 PF08558 0.362
LIG_TYR_ITIM 80 85 PF00017 0.214
LIG_ULM_U2AF65_1 365 370 PF00076 0.308
LIG_WRC_WIRS_1 271 276 PF05994 0.310
LIG_WRPW_2 419 422 PF00400 0.243
LIG_WW_3 2 6 PF00397 0.516
MOD_CDK_SPK_2 46 51 PF00069 0.265
MOD_CK2_1 402 408 PF00069 0.206
MOD_CK2_1 68 74 PF00069 0.265
MOD_GlcNHglycan 150 153 PF01048 0.499
MOD_GlcNHglycan 332 335 PF01048 0.502
MOD_GlcNHglycan 51 54 PF01048 0.638
MOD_GSK3_1 270 277 PF00069 0.307
MOD_GSK3_1 38 45 PF00069 0.441
MOD_GSK3_1 99 106 PF00069 0.355
MOD_N-GLC_1 161 166 PF02516 0.384
MOD_N-GLC_1 38 43 PF02516 0.511
MOD_N-GLC_1 387 392 PF02516 0.616
MOD_N-GLC_1 99 104 PF02516 0.458
MOD_NEK2_1 161 166 PF00069 0.226
MOD_NEK2_1 227 232 PF00069 0.378
MOD_NEK2_1 256 261 PF00069 0.394
MOD_NEK2_1 270 275 PF00069 0.290
MOD_NEK2_1 340 345 PF00069 0.446
MOD_NEK2_1 346 351 PF00069 0.342
MOD_NEK2_1 387 392 PF00069 0.397
MOD_PIKK_1 187 193 PF00454 0.333
MOD_PIKK_1 227 233 PF00454 0.369
MOD_PK_1 402 408 PF00069 0.391
MOD_PKA_1 402 408 PF00069 0.359
MOD_PKA_2 227 233 PF00069 0.326
MOD_PKA_2 402 408 PF00069 0.398
MOD_PKA_2 68 74 PF00069 0.396
MOD_PKB_1 40 48 PF00069 0.289
MOD_Plk_1 161 167 PF00069 0.384
MOD_Plk_1 99 105 PF00069 0.263
MOD_Plk_2-3 68 74 PF00069 0.260
MOD_Plk_4 103 109 PF00069 0.213
MOD_Plk_4 20 26 PF00069 0.425
MOD_Plk_4 372 378 PF00069 0.312
MOD_ProDKin_1 46 52 PF00069 0.296
MOD_SUMO_rev_2 90 97 PF00179 0.345
TRG_DiLeu_BaEn_2 315 321 PF01217 0.223
TRG_DiLeu_BaLyEn_6 30 35 PF01217 0.432
TRG_ENDOCYTIC_2 107 110 PF00928 0.354
TRG_ENDOCYTIC_2 22 25 PF00928 0.323
TRG_ENDOCYTIC_2 260 263 PF00928 0.234
TRG_ENDOCYTIC_2 357 360 PF00928 0.312
TRG_ENDOCYTIC_2 82 85 PF00928 0.373
TRG_ENDOCYTIC_2 91 94 PF00928 0.330
TRG_ER_diArg_1 10 12 PF00400 0.659
TRG_ER_diArg_1 202 205 PF00400 0.420
TRG_ER_diArg_1 242 245 PF00400 0.322
TRG_ER_diArg_1 364 366 PF00400 0.312
TRG_ER_diArg_1 402 404 PF00400 0.327
TRG_Pf-PMV_PEXEL_1 120 124 PF00026 0.538
TRG_Pf-PMV_PEXEL_1 204 208 PF00026 0.620
TRG_Pf-PMV_PEXEL_1 404 408 PF00026 0.608

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P269 Leptomonas seymouri 52% 100%
A0A0N1IJD9 Leptomonas seymouri 28% 76%
A0A0N1PC27 Leptomonas seymouri 31% 96%
A0A0N1PES8 Leptomonas seymouri 58% 98%
A0A1X0NWK3 Trypanosomatidae 33% 100%
A0A1X0NWM3 Trypanosomatidae 34% 100%
A0A3R7N1J7 Trypanosoma rangeli 32% 100%
A0A3S7WZK8 Leishmania donovani 28% 81%
A0A3S7X6F1 Leishmania donovani 32% 94%
A4HDU8 Leishmania braziliensis 73% 100%
A4HL36 Leishmania braziliensis 29% 75%
A4I143 Leishmania infantum 100% 100%
A4I1Y7 Leishmania infantum 29% 100%
A4I8P7 Leishmania infantum 32% 100%
E9AHM5 Leishmania infantum 28% 100%
E9AXX9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
E9AY34 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9B3H7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9B3L0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
Q05889 Leishmania donovani 99% 100%
Q4Q9D9 Leishmania major 28% 100%
Q4QD44 Leishmania major 27% 72%
Q6XFB5 Leishmania major 32% 100%
Q9NC61 Leishmania major 85% 100%
V5AJV9 Trypanosoma cruzi 33% 100%
V5AJW5 Trypanosoma cruzi 33% 100%
V5AM55 Trypanosoma cruzi 32% 100%
V5AR28 Trypanosoma cruzi 33% 100%
V5ASN8 Trypanosoma cruzi 33% 100%
V5AUJ2 Trypanosoma cruzi 33% 100%
V5B2H2 Trypanosoma cruzi 34% 100%
V5B4V1 Trypanosoma cruzi 32% 100%
V5B8H6 Trypanosoma cruzi 32% 100%
V5BB47 Trypanosoma cruzi 32% 100%
V5BRK8 Trypanosoma cruzi 33% 100%
V5BXG8 Trypanosoma cruzi 34% 100%
V5DD11 Trypanosoma cruzi 33% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS