LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H7C1_LEIDO
TriTrypDb:
LdBPK_231140.1 , LdCL_230018700 , LDHU3_23.1500
Length:
392

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7C1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7C1

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 164 168 PF00656 0.641
CLV_C14_Caspase3-7 173 177 PF00656 0.610
CLV_C14_Caspase3-7 182 186 PF00656 0.473
CLV_C14_Caspase3-7 336 340 PF00656 0.685
CLV_NRD_NRD_1 292 294 PF00675 0.460
CLV_NRD_NRD_1 295 297 PF00675 0.496
CLV_NRD_NRD_1 343 345 PF00675 0.683
CLV_NRD_NRD_1 378 380 PF00675 0.572
CLV_PCSK_FUR_1 293 297 PF00082 0.488
CLV_PCSK_KEX2_1 294 296 PF00082 0.481
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PDP9 Leptomonas seymouri 51% 100%
A4HCW6 Leishmania braziliensis 70% 98%
A4I0E6 Leishmania infantum 98% 99%
E9AWA9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 99%
Q4QB66 Leishmania major 89% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS