LeishMANIAdb
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Tropoelastin

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Tropoelastin
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H7A7_LEIDO
TriTrypDb:
LdCL_220012000 , LDHU3_22.1110
Length:
529

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 6, no: 0
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H7A7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H7A7

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_1 1 4 PF02207 0.555
DOC_MAPK_DCC_7 2 11 PF00069 0.511
DOC_MAPK_DCC_7 30 40 PF00069 0.549
DOC_MAPK_gen_1 2 11 PF00069 0.473
DOC_MAPK_MEF2A_6 4 13 PF00069 0.489
DOC_WW_Pin1_4 523 528 PF00397 0.567
LIG_HP1_1 8 12 PF01393 0.481
LIG_SUMO_SIM_par_1 18 23 PF11976 0.604
LIG_SUMO_SIM_par_1 257 262 PF11976 0.509
LIG_SUMO_SIM_par_1 36 41 PF11976 0.566
LIG_SUMO_SIM_par_1 53 58 PF11976 0.523
LIG_SUMO_SIM_par_1 85 90 PF11976 0.515
MOD_GlcNHglycan 22 25 PF01048 0.603
MOD_GSK3_1 519 526 PF00069 0.535
MOD_NEK2_1 20 25 PF00069 0.511
MOD_PK_1 2 8 PF00069 0.486
MOD_ProDKin_1 523 529 PF00069 0.571

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IC81 Leishmania donovani 94% 100%
A0A3Q8IFH2 Leishmania donovani 89% 100%
A0A3S7WX44 Leishmania donovani 87% 81%
A4HZU7 Leishmania infantum 85% 92%
E9AVQ2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
P9WHX6 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 23% 91%
P9WHX7 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 23% 91%
P9WHZ6 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 23% 86%
P9WHZ7 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 23% 86%
P9WI28 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 22% 86%
P9WI29 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 22% 86%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS