LeishMANIAdb
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SH3 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
SH3 domain-containing protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H788_LEIDO
TriTrypDb:
LdBPK_201200.1 * , LdCL_200016551
Length:
349

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H788
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H788

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 114 118 PF00656 0.296
CLV_NRD_NRD_1 170 172 PF00675 0.433
CLV_NRD_NRD_1 229 231 PF00675 0.524
CLV_NRD_NRD_1 343 345 PF00675 0.527
CLV_PCSK_KEX2_1 105 107 PF00082 0.344
CLV_PCSK_KEX2_1 170 172 PF00082 0.433
CLV_PCSK_KEX2_1 229 231 PF00082 0.524
CLV_PCSK_KEX2_1 308 310 PF00082 0.533
CLV_PCSK_KEX2_1 312 314 PF00082 0.547
CLV_PCSK_PC1ET2_1 105 107 PF00082 0.344
CLV_PCSK_PC1ET2_1 308 310 PF00082 0.533
CLV_PCSK_PC1ET2_1 312 314 PF00082 0.547
CLV_PCSK_SKI1_1 171 175 PF00082 0.401
CLV_PCSK_SKI1_1 189 193 PF00082 0.311
CLV_PCSK_SKI1_1 245 249 PF00082 0.370
CLV_PCSK_SKI1_1 309 313 PF00082 0.540
DEG_Nend_UBRbox_3 1 3 PF02207 0.437
DOC_ANK_TNKS_1 120 127 PF00023 0.315
DOC_ANK_TNKS_1 248 255 PF00023 0.408
DOC_CYCLIN_yCln2_LP_2 151 157 PF00134 0.248
DOC_MAPK_MEF2A_6 79 87 PF00069 0.294
DOC_PP2B_LxvP_1 276 279 PF13499 0.513
DOC_PP4_FxxP_1 275 278 PF00568 0.513
DOC_USP7_MATH_1 135 139 PF00917 0.315
DOC_USP7_MATH_1 198 202 PF00917 0.436
DOC_USP7_MATH_1 213 217 PF00917 0.523
DOC_USP7_MATH_1 314 318 PF00917 0.543
DOC_USP7_MATH_1 338 342 PF00917 0.541
DOC_USP7_UBL2_3 308 312 PF12436 0.541
DOC_WW_Pin1_4 289 294 PF00397 0.539
LIG_14-3-3_CanoR_1 329 337 PF00244 0.541
LIG_14-3-3_CanoR_1 344 349 PF00244 0.535
LIG_14-3-3_CanoR_1 46 54 PF00244 0.324
LIG_BRCT_BRCA1_1 2 6 PF00533 0.433
LIG_BRCT_BRCA1_2 2 8 PF00533 0.424
LIG_Clathr_ClatBox_1 161 165 PF01394 0.373
LIG_EVH1_1 276 280 PF00568 0.516
LIG_FHA_1 25 31 PF00498 0.358
LIG_FHA_1 79 85 PF00498 0.304
LIG_FHA_2 206 212 PF00498 0.506
LIG_LIR_Apic_2 48 54 PF02991 0.311
LIG_LIR_Gen_1 241 251 PF02991 0.371
LIG_LIR_Nem_3 117 123 PF02991 0.292
LIG_LIR_Nem_3 241 246 PF02991 0.377
LIG_NRBOX 157 163 PF00104 0.328
LIG_PDZ_Class_1 344 349 PF00595 0.535
LIG_SH2_STAT5 21 24 PF00017 0.319
LIG_SH2_STAT5 55 58 PF00017 0.291
LIG_SH3_1 200 206 PF00018 0.473
LIG_SH3_1 274 280 PF00018 0.517
LIG_SH3_2 269 274 PF14604 0.520
LIG_SH3_2 277 282 PF14604 0.521
LIG_SH3_3 129 135 PF00018 0.292
LIG_SH3_3 200 206 PF00018 0.473
LIG_SH3_3 260 266 PF00018 0.494
LIG_SH3_3 274 280 PF00018 0.517
LIG_SH3_3 95 101 PF00018 0.375
LIG_SH3_4 302 309 PF00018 0.539
LIG_SH3_CIN85_PxpxPR_1 265 270 PF14604 0.522
LIG_WW_3 292 296 PF00397 0.534
LIG_WW_3 320 324 PF00397 0.539
MOD_CDK_SPxK_1 289 295 PF00069 0.541
MOD_CK1_1 24 30 PF00069 0.352
MOD_CK1_1 45 51 PF00069 0.352
MOD_CK2_1 205 211 PF00069 0.504
MOD_CK2_1 213 219 PF00069 0.525
MOD_GlcNHglycan 13 16 PF01048 0.333
MOD_GlcNHglycan 137 140 PF01048 0.293
MOD_GSK3_1 135 142 PF00069 0.305
MOD_GSK3_1 17 24 PF00069 0.316
MOD_GSK3_1 211 218 PF00069 0.519
MOD_GSK3_1 37 44 PF00069 0.356
MOD_GSK3_1 9 16 PF00069 0.365
MOD_LATS_1 300 306 PF00433 0.531
MOD_N-GLC_1 62 67 PF02516 0.315
MOD_NEK2_1 116 121 PF00069 0.291
MOD_NEK2_1 17 22 PF00069 0.314
MOD_PIKK_1 163 169 PF00454 0.394
MOD_PIKK_1 302 308 PF00454 0.537
MOD_PIKK_1 332 338 PF00454 0.540
MOD_PIKK_1 45 51 PF00454 0.352
MOD_PKA_2 223 229 PF00069 0.528
MOD_PKA_2 294 300 PF00069 0.535
MOD_PKA_2 330 336 PF00069 0.542
MOD_PKA_2 45 51 PF00069 0.352
MOD_Plk_1 116 122 PF00069 0.284
MOD_Plk_2-3 111 117 PF00069 0.274
MOD_Plk_4 157 163 PF00069 0.328
MOD_ProDKin_1 289 295 PF00069 0.541
TRG_DiLeu_BaEn_2 185 191 PF01217 0.331
TRG_ENDOCYTIC_2 120 123 PF00928 0.276
TRG_ER_diArg_1 200 203 PF00400 0.455
TRG_ER_diArg_1 322 325 PF00400 0.549
TRG_ER_diArg_1 328 331 PF00400 0.545
TRG_ER_diLys_1 345 349 PF00400 0.534
TRG_NLS_MonoExtN_4 343 348 PF00514 0.530
TRG_Pf-PMV_PEXEL_1 106 110 PF00026 0.318
TRG_Pf-PMV_PEXEL_1 193 197 PF00026 0.339

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS