Clathrin light chain

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H749_LEIDO

TriTrypDb:

LdBPK_190100.1 , LdCL_190006000 , LDHU3_19.0110

Length:

395

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0030117	membrane coat	3	3
GO:0030118	clathrin coat	4	3
GO:0030120	vesicle coat	4	3
GO:0030125	clathrin vesicle coat	5	3
GO:0030130	clathrin coat of trans-Golgi network vesicle	6	3
GO:0030132	clathrin coat of coated pit	4	3
GO:0032991	protein-containing complex	1	3
GO:0098796	membrane protein complex	2	3
GO:0098797	plasma membrane protein complex	3	3

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Expansion

Sequence features

A0A3S5H749

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H749

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	3
GO:0006886	intracellular protein transport	4	3
GO:0008104	protein localization	4	3
GO:0009987	cellular process	1	3
GO:0015031	protein transport	4	3
GO:0016192	vesicle-mediated transport	4	3
GO:0033036	macromolecule localization	2	3
GO:0045184	establishment of protein localization	3	3
GO:0046907	intracellular transport	3	3
GO:0051179	localization	1	3

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Molecular functions
Term	Name	Level	Count
GO:0005198	structural molecule activity	1	3

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	103	107	PF00656	0.511
CLV_NRD_NRD_1	55	57	PF00675	0.423
CLV_PCSK_KEX2_1	326	328	PF00082	0.312
CLV_PCSK_KEX2_1	353	355	PF00082	0.330
CLV_PCSK_KEX2_1	55	57	PF00082	0.423
CLV_PCSK_PC1ET2_1	326	328	PF00082	0.312
CLV_PCSK_PC1ET2_1	353	355	PF00082	0.330
CLV_PCSK_SKI1_1	311	315	PF00082	0.432
CLV_PCSK_SKI1_1	382	386	PF00082	0.253
DEG_APCC_DBOX_1	381	389	PF00400	0.253

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
E9AGR3	Leishmania infantum	100%	100%

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