LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H738_LEIDO
TriTrypDb:
LdCL_180015500 , LDHU3_18.1290
Length:
107

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 2, no: 0
NetGPI no yes: 0, no: 2
Cellular components
Term Name Level Count
GO:0016020 membrane 2 3
GO:0110165 cellular anatomical entity 1 3

Expansion

Sequence features

A0A3S5H738
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H738

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 100 104 PF00656 0.601
CLV_NRD_NRD_1 81 83 PF00675 0.323
CLV_NRD_NRD_1 88 90 PF00675 0.326
CLV_PCSK_FUR_1 86 90 PF00082 0.347
CLV_PCSK_KEX2_1 83 85 PF00082 0.327
CLV_PCSK_KEX2_1 88 90 PF00082 0.326
CLV_PCSK_PC1ET2_1 83 85 PF00082 0.323
CLV_PCSK_PC7_1 84 90 PF00082 0.348
DOC_PP4_FxxP_1 18 21 PF00568 0.453
DOC_WW_Pin1_4 17 22 PF00397 0.394
LIG_BIR_II_1 1 5 PF00653 0.407
LIG_BRCT_BRCA1_1 53 57 PF00533 0.273
LIG_LIR_Gen_1 54 65 PF02991 0.273
LIG_LIR_Nem_3 54 60 PF02991 0.273
LIG_Sin3_3 44 51 PF02671 0.273
LIG_TRAF2_1 73 76 PF00917 0.575
LIG_TRAF2_1 91 94 PF00917 0.559
MOD_CK2_1 70 76 PF00069 0.560
MOD_GlcNHglycan 1 4 PF01048 0.569
MOD_N-GLC_1 34 39 PF02516 0.525
MOD_Plk_4 56 62 PF00069 0.350
MOD_ProDKin_1 17 23 PF00069 0.397
MOD_SUMO_for_1 97 100 PF00179 0.551
TRG_ER_diArg_1 82 85 PF00400 0.526
TRG_ER_diArg_1 88 90 PF00400 0.526
TRG_NLS_MonoExtC_3 81 86 PF00514 0.525

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMJ0 Leptomonas seymouri 55% 99%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS