Dpy-30_motif_containing_protein_putative/Pfam:PF0 5186

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Dpy-30 motif containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H731_LEIDO

TriTrypDb:

LdCL_180011200 , LDHU3_18.0810

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0032991	protein-containing complex	1	1
GO:0034708	methyltransferase complex	4	1
GO:0035097	histone methyltransferase complex	3	1
GO:0044666	MLL3/4 complex	4	1
GO:0048188	Set1C/COMPASS complex	4	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

A0A3S5H731

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H731

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	12	16	PF00656	0.482
CLV_C14_Caspase3-7	5	9	PF00656	0.595
CLV_PCSK_SKI1_1	92	96	PF00082	0.327
DEG_APCC_DBOX_1	22	30	PF00400	0.547
DEG_APCC_DBOX_1	91	99	PF00400	0.527
DEG_Nend_Nbox_1	1	3	PF02207	0.707
DOC_CKS1_1	42	47	PF01111	0.602
DOC_MAPK_MEF2A_6	92	99	PF00069	0.527
DOC_MAPK_NFAT4_5	92	100	PF00069	0.527
DOC_USP7_MATH_1	153	157	PF00917	0.667
DOC_USP7_MATH_1	174	178	PF00917	0.604
DOC_USP7_MATH_1	7	11	PF00917	0.534
DOC_USP7_UBL2_3	128	132	PF12436	0.535
DOC_WW_Pin1_4	155	160	PF00397	0.625
DOC_WW_Pin1_4	41	46	PF00397	0.610
LIG_BRCT_BRCA1_1	52	56	PF00533	0.678
LIG_BRCT_BRCA1_1	57	61	PF00533	0.563
LIG_FHA_2	3	9	PF00498	0.596
LIG_FHA_2	35	41	PF00498	0.657
LIG_LIR_Apic_2	81	85	PF02991	0.523
LIG_LIR_Nem_3	58	64	PF02991	0.654
LIG_SH2_NCK_1	82	86	PF00017	0.520
LIG_SH2_STAT5	89	92	PF00017	0.527
LIG_SH3_3	107	113	PF00018	0.518
LIG_SH3_3	123	129	PF00018	0.508
LIG_SH3_3	146	152	PF00018	0.517
LIG_SH3_3	39	45	PF00018	0.672
LIG_SH3_4	128	135	PF00018	0.515
LIG_TRAF2_1	37	40	PF00917	0.664
MOD_CK1_1	137	143	PF00069	0.651
MOD_CK1_1	170	176	PF00069	0.646
MOD_CK1_1	177	183	PF00069	0.636
MOD_CK1_1	194	200	PF00069	0.652
MOD_CK1_1	59	65	PF00069	0.473
MOD_CK2_1	34	40	PF00069	0.658
MOD_GlcNHglycan	136	139	PF01048	0.725
MOD_GlcNHglycan	149	152	PF01048	0.604
MOD_GlcNHglycan	154	158	PF01048	0.584
MOD_GlcNHglycan	172	175	PF01048	0.529
MOD_GlcNHglycan	179	182	PF01048	0.590
MOD_GlcNHglycan	53	56	PF01048	0.542
MOD_GlcNHglycan	58	61	PF01048	0.523
MOD_GSK3_1	170	177	PF00069	0.625
MOD_GSK3_1	180	187	PF00069	0.608
MOD_GSK3_1	51	58	PF00069	0.572
MOD_GSK3_1	62	69	PF00069	0.470
MOD_N-GLC_1	177	182	PF02516	0.641
MOD_NEK2_1	1	6	PF00069	0.700
MOD_NEK2_1	172	177	PF00069	0.728
MOD_NEK2_1	34	39	PF00069	0.720
MOD_NEK2_1	48	53	PF00069	0.633
MOD_NEK2_1	56	61	PF00069	0.640
MOD_PIKK_1	35	41	PF00454	0.561
MOD_PKA_2	170	176	PF00069	0.714
MOD_Plk_1	7	13	PF00069	0.668
MOD_Plk_1	90	96	PF00069	0.527
MOD_ProDKin_1	155	161	PF00069	0.624
MOD_ProDKin_1	41	47	PF00069	0.609
MOD_SUMO_rev_2	194	200	PF00179	0.522
TRG_DiLeu_BaLyEn_6	93	98	PF01217	0.527

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB06	Leptomonas seymouri	43%	88%
A4H9H0	Leishmania braziliensis	68%	100%