LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H6S5_LEIDO
TriTrypDb:
LdBPK_141070.1 , LdCL_140016400 , LDHU3_14.1340
Length:
1019

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H6S5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6S5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 138 142 PF00656 0.704
CLV_C14_Caspase3-7 166 170 PF00656 0.629
CLV_C14_Caspase3-7 625 629 PF00656 0.606
CLV_C14_Caspase3-7 67 71 PF00656 0.651
CLV_C14_Caspase3-7 763 767 PF00656 0.398
CLV_C14_Caspase3-7 905 909 PF00656 0.483
CLV_NRD_NRD_1 114 116 PF00675 0.807
CLV_NRD_NRD_1 226 228 PF00675 0.571
CLV_NRD_NRD_1 272 274 PF00675 0.538
CLV_NRD_NRD_1 359 361 PF00675 0.527
CLV_NRD_NRD_1 368 370 PF00675 0.439
CLV_NRD_NRD_1 41 43 PF00675 0.624
CLV_NRD_NRD_1 446 448 PF00675 0.614
CLV_NRD_NRD_1 491 493 PF00675 0.741
CLV_NRD_NRD_1 8 10 PF00675 0.656
CLV_NRD_NRD_1 890 892 PF00675 0.485
CLV_NRD_NRD_1 943 945 PF00675 0.465
CLV_NRD_NRD_1 969 971 PF00675 0.552
CLV_PCSK_FUR_1 111 115 PF00082 0.637
CLV_PCSK_KEX2_1 111 113 PF00082 0.702
CLV_PCSK_KEX2_1 114 116 PF00082 0.791
CLV_PCSK_KEX2_1 226 228 PF00082 0.570
CLV_PCSK_KEX2_1 272 274 PF00082 0.538
CLV_PCSK_KEX2_1 368 370 PF00082 0.471
CLV_PCSK_KEX2_1 41 43 PF00082 0.691
CLV_PCSK_KEX2_1 446 448 PF00082 0.738
CLV_PCSK_KEX2_1 491 493 PF00082 0.741
CLV_PCSK_KEX2_1 590 592 PF00082 0.612
CLV_PCSK_KEX2_1 8 10 PF00082 0.666
CLV_PCSK_KEX2_1 889 891 PF00082 0.492
CLV_PCSK_KEX2_1 943 945 PF00082 0.465
CLV_PCSK_KEX2_1 969 971 PF00082 0.531
CLV_PCSK_PC1ET2_1 590 592 PF00082 0.547
CLV_PCSK_PC7_1 107 113 PF00082 0.636
CLV_PCSK_SKI1_1 191 195 PF00082 0.544
CLV_PCSK_SKI1_1 285 289 PF00082 0.423
CLV_PCSK_SKI1_1 305 309 PF00082 0.340
CLV_PCSK_SKI1_1 343 347 PF00082 0.454
CLV_PCSK_SKI1_1 384 388 PF00082 0.561
CLV_PCSK_SKI1_1 424 428 PF00082 0.492
CLV_PCSK_SKI1_1 477 481 PF00082 0.493
CLV_PCSK_SKI1_1 507 511 PF00082 0.536
CLV_PCSK_SKI1_1 590 594 PF00082 0.522
CLV_PCSK_SKI1_1 640 644 PF00082 0.561
CLV_PCSK_SKI1_1 743 747 PF00082 0.405
CLV_PCSK_SKI1_1 789 793 PF00082 0.473
CLV_PCSK_SKI1_1 8 12 PF00082 0.644
CLV_PCSK_SKI1_1 848 852 PF00082 0.507
CLV_PCSK_SKI1_1 911 915 PF00082 0.423
CLV_PCSK_SKI1_1 943 947 PF00082 0.494
CLV_Separin_Metazoa 195 199 PF03568 0.538
DEG_APCC_DBOX_1 190 198 PF00400 0.545
DEG_APCC_DBOX_1 40 48 PF00400 0.560
DEG_APCC_DBOX_1 716 724 PF00400 0.583
DEG_APCC_DBOX_1 957 965 PF00400 0.442
DEG_SPOP_SBC_1 415 419 PF00917 0.486
DEG_SPOP_SBC_1 650 654 PF00917 0.589
DOC_CKS1_1 37 42 PF01111 0.574
DOC_CYCLIN_RxL_1 5 15 PF00134 0.588
DOC_MAPK_gen_1 29 37 PF00069 0.674
DOC_MAPK_gen_1 303 311 PF00069 0.458
DOC_MAPK_gen_1 368 374 PF00069 0.407
DOC_MAPK_MEF2A_6 285 292 PF00069 0.461
DOC_MAPK_MEF2A_6 303 311 PF00069 0.529
DOC_MAPK_MEF2A_6 332 341 PF00069 0.464
DOC_MAPK_NFAT4_5 285 293 PF00069 0.417
DOC_PP1_RVXF_1 341 348 PF00149 0.461
DOC_PP1_RVXF_1 741 747 PF00149 0.413
DOC_PP2B_LxvP_1 10 13 PF13499 0.544
DOC_PP2B_LxvP_1 47 50 PF13499 0.772
DOC_PP4_FxxP_1 93 96 PF00568 0.732
DOC_USP7_MATH_1 118 122 PF00917 0.718
DOC_USP7_MATH_1 131 135 PF00917 0.567
DOC_USP7_MATH_1 163 167 PF00917 0.634
DOC_USP7_MATH_1 211 215 PF00917 0.624
DOC_USP7_MATH_1 234 238 PF00917 0.510
DOC_USP7_MATH_1 468 472 PF00917 0.516
DOC_USP7_MATH_1 475 479 PF00917 0.492
DOC_USP7_MATH_1 567 571 PF00917 0.719
DOC_USP7_MATH_1 585 589 PF00917 0.481
DOC_USP7_MATH_1 650 654 PF00917 0.589
DOC_USP7_MATH_1 677 681 PF00917 0.529
DOC_USP7_MATH_1 711 715 PF00917 0.613
DOC_USP7_MATH_1 75 79 PF00917 0.739
DOC_USP7_MATH_1 785 789 PF00917 0.453
DOC_USP7_MATH_1 863 867 PF00917 0.634
DOC_USP7_MATH_1 96 100 PF00917 0.769
DOC_WW_Pin1_4 157 162 PF00397 0.709
DOC_WW_Pin1_4 172 177 PF00397 0.509
DOC_WW_Pin1_4 277 282 PF00397 0.508
DOC_WW_Pin1_4 317 322 PF00397 0.665
DOC_WW_Pin1_4 331 336 PF00397 0.552
DOC_WW_Pin1_4 359 364 PF00397 0.575
DOC_WW_Pin1_4 36 41 PF00397 0.732
DOC_WW_Pin1_4 462 467 PF00397 0.570
DOC_WW_Pin1_4 50 55 PF00397 0.587
DOC_WW_Pin1_4 562 567 PF00397 0.594
DOC_WW_Pin1_4 651 656 PF00397 0.643
DOC_WW_Pin1_4 703 708 PF00397 0.610
DOC_WW_Pin1_4 826 831 PF00397 0.613
DOC_WW_Pin1_4 838 843 PF00397 0.531
DOC_WW_Pin1_4 858 863 PF00397 0.457
DOC_WW_Pin1_4 875 880 PF00397 0.577
DOC_WW_Pin1_4 932 937 PF00397 0.534
DOC_WW_Pin1_4 951 956 PF00397 0.333
DOC_WW_Pin1_4 983 988 PF00397 0.619
LIG_14-3-3_CanoR_1 215 225 PF00244 0.649
LIG_14-3-3_CanoR_1 272 276 PF00244 0.486
LIG_14-3-3_CanoR_1 369 375 PF00244 0.422
LIG_14-3-3_CanoR_1 41 50 PF00244 0.678
LIG_14-3-3_CanoR_1 446 454 PF00244 0.670
LIG_14-3-3_CanoR_1 521 529 PF00244 0.711
LIG_14-3-3_CanoR_1 649 655 PF00244 0.568
LIG_14-3-3_CanoR_1 695 702 PF00244 0.464
LIG_14-3-3_CanoR_1 73 82 PF00244 0.745
LIG_14-3-3_CanoR_1 958 962 PF00244 0.419
LIG_Actin_WH2_2 398 415 PF00022 0.464
LIG_Actin_WH2_2 915 930 PF00022 0.450
LIG_BIR_III_4 583 587 PF00653 0.545
LIG_BRCT_BRCA1_1 569 573 PF00533 0.626
LIG_Clathr_ClatBox_1 308 312 PF01394 0.464
LIG_deltaCOP1_diTrp_1 793 798 PF00928 0.439
LIG_deltaCOP1_diTrp_1 900 906 PF00928 0.464
LIG_FHA_1 124 130 PF00498 0.690
LIG_FHA_1 292 298 PF00498 0.496
LIG_FHA_1 32 38 PF00498 0.557
LIG_FHA_1 400 406 PF00498 0.494
LIG_FHA_1 604 610 PF00498 0.493
LIG_FHA_1 632 638 PF00498 0.725
LIG_FHA_1 811 817 PF00498 0.483
LIG_FHA_1 826 832 PF00498 0.488
LIG_FHA_1 849 855 PF00498 0.433
LIG_FHA_1 89 95 PF00498 0.594
LIG_FHA_2 416 422 PF00498 0.481
LIG_FHA_2 430 436 PF00498 0.435
LIG_FHA_2 484 490 PF00498 0.614
LIG_FHA_2 577 583 PF00498 0.635
LIG_FHA_2 63 69 PF00498 0.625
LIG_LIR_Apic_2 836 842 PF02991 0.605
LIG_LIR_Apic_2 91 96 PF02991 0.729
LIG_LIR_Gen_1 419 430 PF02991 0.532
LIG_LIR_Gen_1 659 667 PF02991 0.471
LIG_LIR_Nem_3 254 259 PF02991 0.559
LIG_LIR_Nem_3 419 425 PF02991 0.497
LIG_LIR_Nem_3 659 664 PF02991 0.535
LIG_LIR_Nem_3 813 817 PF02991 0.438
LIG_MYND_1 462 466 PF01753 0.602
LIG_MYND_1 732 736 PF01753 0.458
LIG_NRBOX 1011 1017 PF00104 0.517
LIG_NRBOX 285 291 PF00104 0.479
LIG_NRBOX 588 594 PF00104 0.567
LIG_PCNA_yPIPBox_3 178 191 PF02747 0.546
LIG_Pex14_1 342 346 PF04695 0.403
LIG_Rb_LxCxE_1 192 214 PF01857 0.572
LIG_RPA_C_Fungi 222 234 PF08784 0.555
LIG_SH2_CRK 814 818 PF00017 0.442
LIG_SH2_CRK 839 843 PF00017 0.539
LIG_SH2_SRC 768 771 PF00017 0.459
LIG_SH2_STAT5 768 771 PF00017 0.459
LIG_SH3_1 151 157 PF00018 0.571
LIG_SH3_1 332 338 PF00018 0.465
LIG_SH3_2 335 340 PF14604 0.545
LIG_SH3_3 151 157 PF00018 0.701
LIG_SH3_3 275 281 PF00018 0.527
LIG_SH3_3 332 338 PF00018 0.596
LIG_SH3_3 51 57 PF00018 0.650
LIG_SH3_3 639 645 PF00018 0.613
LIG_SH3_3 673 679 PF00018 0.447
LIG_SH3_3 722 728 PF00018 0.678
LIG_SH3_3 730 736 PF00018 0.535
LIG_SH3_3 859 865 PF00018 0.596
LIG_SH3_3 930 936 PF00018 0.516
LIG_SH3_3 949 955 PF00018 0.392
LIG_Sin3_3 850 857 PF02671 0.496
LIG_SUMO_SIM_anti_2 192 198 PF11976 0.500
LIG_SUMO_SIM_anti_2 402 409 PF11976 0.467
LIG_SUMO_SIM_anti_2 708 714 PF11976 0.548
LIG_SUMO_SIM_anti_2 918 923 PF11976 0.392
LIG_SUMO_SIM_par_1 288 294 PF11976 0.587
LIG_SUMO_SIM_par_1 306 312 PF11976 0.355
LIG_SUMO_SIM_par_1 408 414 PF11976 0.457
LIG_TRAF2_1 249 252 PF00917 0.510
LIG_TRAF2_1 378 381 PF00917 0.368
LIG_Vh1_VBS_1 912 930 PF01044 0.477
LIG_WRC_WIRS_1 371 376 PF05994 0.420
MOD_CDK_SPK_2 280 285 PF00069 0.469
MOD_CDK_SPK_2 36 41 PF00069 0.573
MOD_CDK_SPK_2 932 937 PF00069 0.513
MOD_CDK_SPxK_1 36 42 PF00069 0.581
MOD_CDK_SPxxK_3 951 958 PF00069 0.460
MOD_CK1_1 121 127 PF00069 0.644
MOD_CK1_1 14 20 PF00069 0.601
MOD_CK1_1 172 178 PF00069 0.691
MOD_CK1_1 218 224 PF00069 0.595
MOD_CK1_1 279 285 PF00069 0.504
MOD_CK1_1 316 322 PF00069 0.758
MOD_CK1_1 389 395 PF00069 0.579
MOD_CK1_1 442 448 PF00069 0.612
MOD_CK1_1 483 489 PF00069 0.614
MOD_CK1_1 631 637 PF00069 0.546
MOD_CK1_1 64 70 PF00069 0.744
MOD_CK1_1 651 657 PF00069 0.514
MOD_CK1_1 680 686 PF00069 0.595
MOD_CK1_1 835 841 PF00069 0.611
MOD_CK1_1 977 983 PF00069 0.579
MOD_CK2_1 121 127 PF00069 0.669
MOD_CK2_1 246 252 PF00069 0.478
MOD_CK2_1 320 326 PF00069 0.600
MOD_CK2_1 370 376 PF00069 0.473
MOD_CK2_1 415 421 PF00069 0.490
MOD_CK2_1 468 474 PF00069 0.467
MOD_CK2_1 613 619 PF00069 0.537
MOD_CK2_1 62 68 PF00069 0.698
MOD_CK2_1 951 957 PF00069 0.493
MOD_CK2_1 991 997 PF00069 0.615
MOD_CMANNOS 268 271 PF00535 0.438
MOD_CMANNOS 795 798 PF00535 0.401
MOD_Cter_Amidation 967 970 PF01082 0.578
MOD_GlcNHglycan 120 123 PF01048 0.642
MOD_GlcNHglycan 135 138 PF01048 0.704
MOD_GlcNHglycan 165 168 PF01048 0.656
MOD_GlcNHglycan 171 174 PF01048 0.570
MOD_GlcNHglycan 2 5 PF01048 0.701
MOD_GlcNHglycan 220 223 PF01048 0.592
MOD_GlcNHglycan 228 231 PF01048 0.587
MOD_GlcNHglycan 24 27 PF01048 0.623
MOD_GlcNHglycan 316 319 PF01048 0.741
MOD_GlcNHglycan 389 392 PF01048 0.550
MOD_GlcNHglycan 447 450 PF01048 0.657
MOD_GlcNHglycan 466 469 PF01048 0.521
MOD_GlcNHglycan 525 528 PF01048 0.611
MOD_GlcNHglycan 679 682 PF01048 0.677
MOD_GlcNHglycan 70 73 PF01048 0.814
MOD_GlcNHglycan 713 716 PF01048 0.699
MOD_GlcNHglycan 749 752 PF01048 0.557
MOD_GlcNHglycan 79 82 PF01048 0.605
MOD_GlcNHglycan 915 918 PF01048 0.391
MOD_GlcNHglycan 976 979 PF01048 0.720
MOD_GSK3_1 117 124 PF00069 0.797
MOD_GSK3_1 131 138 PF00069 0.619
MOD_GSK3_1 165 172 PF00069 0.601
MOD_GSK3_1 211 218 PF00069 0.658
MOD_GSK3_1 276 283 PF00069 0.602
MOD_GSK3_1 313 320 PF00069 0.587
MOD_GSK3_1 464 471 PF00069 0.522
MOD_GSK3_1 62 69 PF00069 0.723
MOD_GSK3_1 624 631 PF00069 0.621
MOD_GSK3_1 711 718 PF00069 0.695
MOD_GSK3_1 77 84 PF00069 0.634
MOD_GSK3_1 806 813 PF00069 0.558
MOD_GSK3_1 821 828 PF00069 0.465
MOD_GSK3_1 830 837 PF00069 0.639
MOD_GSK3_1 863 870 PF00069 0.687
MOD_GSK3_1 913 920 PF00069 0.418
MOD_LATS_1 224 230 PF00433 0.562
MOD_LATS_1 503 509 PF00433 0.508
MOD_N-GLC_1 314 319 PF02516 0.532
MOD_N-GLC_1 613 618 PF02516 0.538
MOD_N-GLC_1 628 633 PF02516 0.514
MOD_N-GLC_2 354 356 PF02516 0.523
MOD_NEK2_1 184 189 PF00069 0.502
MOD_NEK2_1 22 27 PF00069 0.614
MOD_NEK2_1 246 251 PF00069 0.582
MOD_NEK2_1 313 318 PF00069 0.501
MOD_NEK2_1 387 392 PF00069 0.737
MOD_NEK2_1 401 406 PF00069 0.454
MOD_NEK2_1 480 485 PF00069 0.576
MOD_NEK2_1 613 618 PF00069 0.631
MOD_NEK2_1 747 752 PF00069 0.408
MOD_NEK2_1 772 777 PF00069 0.417
MOD_NEK2_1 820 825 PF00069 0.471
MOD_NEK2_1 834 839 PF00069 0.555
MOD_NEK2_1 885 890 PF00069 0.641
MOD_NEK2_1 922 927 PF00069 0.426
MOD_NEK2_2 585 590 PF00069 0.553
MOD_PIKK_1 12 18 PF00454 0.599
MOD_PIKK_1 205 211 PF00454 0.562
MOD_PIKK_1 361 367 PF00454 0.543
MOD_PIKK_1 454 460 PF00454 0.602
MOD_PIKK_1 631 637 PF00454 0.704
MOD_PIKK_1 772 778 PF00454 0.445
MOD_PIKK_1 783 789 PF00454 0.497
MOD_PIKK_1 88 94 PF00454 0.655
MOD_PKA_1 226 232 PF00069 0.607
MOD_PKA_1 439 445 PF00069 0.609
MOD_PKA_1 890 896 PF00069 0.464
MOD_PKA_2 106 112 PF00069 0.570
MOD_PKA_2 226 232 PF00069 0.595
MOD_PKA_2 271 277 PF00069 0.452
MOD_PKA_2 298 304 PF00069 0.662
MOD_PKA_2 445 451 PF00069 0.586
MOD_PKA_2 648 654 PF00069 0.567
MOD_PKA_2 677 683 PF00069 0.492
MOD_PKA_2 890 896 PF00069 0.478
MOD_PKA_2 957 963 PF00069 0.423
MOD_PKA_2 968 974 PF00069 0.518
MOD_PKB_1 519 527 PF00069 0.542
MOD_Plk_1 251 257 PF00069 0.538
MOD_Plk_1 428 434 PF00069 0.626
MOD_Plk_1 613 619 PF00069 0.537
MOD_Plk_1 627 633 PF00069 0.520
MOD_Plk_1 917 923 PF00069 0.408
MOD_Plk_1 97 103 PF00069 0.535
MOD_Plk_2-3 429 435 PF00069 0.488
MOD_Plk_2-3 628 634 PF00069 0.570
MOD_Plk_4 251 257 PF00069 0.503
MOD_Plk_4 370 376 PF00069 0.420
MOD_Plk_4 475 481 PF00069 0.470
MOD_Plk_4 917 923 PF00069 0.408
MOD_Plk_4 957 963 PF00069 0.423
MOD_Plk_4 97 103 PF00069 0.557
MOD_ProDKin_1 157 163 PF00069 0.705
MOD_ProDKin_1 172 178 PF00069 0.503
MOD_ProDKin_1 277 283 PF00069 0.499
MOD_ProDKin_1 317 323 PF00069 0.669
MOD_ProDKin_1 331 337 PF00069 0.544
MOD_ProDKin_1 359 365 PF00069 0.572
MOD_ProDKin_1 36 42 PF00069 0.733
MOD_ProDKin_1 462 468 PF00069 0.565
MOD_ProDKin_1 50 56 PF00069 0.587
MOD_ProDKin_1 562 568 PF00069 0.595
MOD_ProDKin_1 651 657 PF00069 0.640
MOD_ProDKin_1 703 709 PF00069 0.612
MOD_ProDKin_1 826 832 PF00069 0.616
MOD_ProDKin_1 838 844 PF00069 0.525
MOD_ProDKin_1 858 864 PF00069 0.466
MOD_ProDKin_1 875 881 PF00069 0.575
MOD_ProDKin_1 932 938 PF00069 0.528
MOD_ProDKin_1 951 957 PF00069 0.332
MOD_ProDKin_1 983 989 PF00069 0.623
MOD_SUMO_for_1 426 429 PF00179 0.486
TRG_DiLeu_BaEn_1 403 408 PF01217 0.531
TRG_DiLeu_BaEn_1 421 426 PF01217 0.364
TRG_DiLeu_BaEn_1 957 962 PF01217 0.503
TRG_DiLeu_BaLyEn_6 588 593 PF01217 0.511
TRG_DiLeu_BaLyEn_6 6 11 PF01217 0.670
TRG_DiLeu_BaLyEn_6 730 735 PF01217 0.543
TRG_DiLeu_LyEn_5 421 426 PF01217 0.487
TRG_DiLeu_LyEn_5 459 464 PF01217 0.609
TRG_ENDOCYTIC_2 814 817 PF00928 0.441
TRG_ENDOCYTIC_2 939 942 PF00928 0.497
TRG_ER_diArg_1 111 114 PF00400 0.701
TRG_ER_diArg_1 151 154 PF00400 0.618
TRG_ER_diArg_1 225 227 PF00400 0.608
TRG_ER_diArg_1 271 273 PF00400 0.527
TRG_ER_diArg_1 302 305 PF00400 0.651
TRG_ER_diArg_1 40 42 PF00400 0.685
TRG_ER_diArg_1 490 492 PF00400 0.731
TRG_ER_diArg_1 504 507 PF00400 0.511
TRG_ER_diArg_1 7 9 PF00400 0.683
TRG_ER_diArg_1 798 801 PF00400 0.402
TRG_ER_diArg_1 889 891 PF00400 0.492
TRG_ER_diArg_1 942 944 PF00400 0.455
TRG_ER_diArg_1 969 972 PF00400 0.531
TRG_Pf-PMV_PEXEL_1 343 348 PF00026 0.487
TRG_Pf-PMV_PEXEL_1 424 428 PF00026 0.492
TRG_Pf-PMV_PEXEL_1 943 947 PF00026 0.413

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P483 Leptomonas seymouri 31% 100%
A4H7Q4 Leishmania braziliensis 66% 100%
A4HW43 Leishmania infantum 100% 100%
E9APU6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
Q4QFN4 Leishmania major 89% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS