Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S5H6P7_LEIDO

TriTrypDb:

LdCL_130017100 , LDHU3_13.1430

Length:

148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A0A3S5H6P7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6P7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	143	147	PF00656	0.604
CLV_NRD_NRD_1	19	21	PF00675	0.513
CLV_NRD_NRD_1	83	85	PF00675	0.312
CLV_NRD_NRD_1	96	98	PF00675	0.340
CLV_PCSK_FUR_1	94	98	PF00082	0.339
CLV_PCSK_KEX2_1	111	113	PF00082	0.370
CLV_PCSK_KEX2_1	83	85	PF00082	0.312
CLV_PCSK_KEX2_1	96	98	PF00082	0.340
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.370
CLV_PCSK_SKI1_1	7	11	PF00082	0.555
CLV_PCSK_SKI1_1	83	87	PF00082	0.314
DOC_MAPK_gen_1	94	104	PF00069	0.534
DOC_MAPK_MEF2A_6	54	63	PF00069	0.199
DOC_USP7_MATH_1	144	148	PF00917	0.603
DOC_USP7_MATH_1	75	79	PF00917	0.311
DOC_WW_Pin1_4	123	128	PF00397	0.600
DOC_WW_Pin1_4	129	134	PF00397	0.600
LIG_14-3-3_CanoR_1	128	134	PF00244	0.601
LIG_14-3-3_CanoR_1	7	12	PF00244	0.353
LIG_14-3-3_CanoR_1	94	104	PF00244	0.534
LIG_BIR_II_1	1	5	PF00653	0.372
LIG_deltaCOP1_diTrp_1	55	60	PF00928	0.199
LIG_FHA_1	137	143	PF00498	0.607
LIG_LIR_Gen_1	55	66	PF02991	0.199
LIG_LIR_Nem_3	26	31	PF02991	0.332
LIG_LIR_Nem_3	55	61	PF02991	0.199
LIG_LIR_Nem_3	78	82	PF02991	0.493
LIG_SH2_CRK	28	32	PF00017	0.327
LIG_SH2_CRK	44	48	PF00017	0.338
LIG_SH2_CRK	82	86	PF00017	0.509
LIG_SH2_NCK_1	44	48	PF00017	0.338
LIG_SH2_PTP2	58	61	PF00017	0.199
LIG_SH2_STAT5	17	20	PF00017	0.323
LIG_SH2_STAT5	23	26	PF00017	0.323
LIG_SH2_STAT5	58	61	PF00017	0.199
LIG_SH3_3	131	137	PF00018	0.602
LIG_SH3_3	6	12	PF00018	0.355
LIG_SUMO_SIM_par_1	65	71	PF11976	0.199
LIG_TYR_ITIM	56	61	PF00017	0.199
LIG_UBA3_1	104	111	PF00899	0.545
LIG_UBA3_1	42	50	PF00899	0.339
LIG_WRC_WIRS_1	76	81	PF05994	0.322
MOD_CDK_SPK_2	123	128	PF00069	0.600
MOD_CDK_SPxxK_3	133	140	PF00069	0.604
MOD_CK1_1	106	112	PF00069	0.551
MOD_CK1_1	136	142	PF00069	0.605
MOD_CK2_1	129	135	PF00069	0.601
MOD_CMANNOS	57	60	PF00535	0.199
MOD_Cter_Amidation	18	21	PF01082	0.516
MOD_GlcNHglycan	114	117	PF01048	0.387
MOD_GlcNHglycan	98	101	PF01048	0.326
MOD_GSK3_1	106	113	PF00069	0.553
MOD_GSK3_1	114	121	PF00069	0.590
MOD_GSK3_1	123	130	PF00069	0.599
MOD_GSK3_1	23	30	PF00069	0.329
MOD_LATS_1	110	116	PF00433	0.575
MOD_NEK2_1	1	6	PF00069	0.371
MOD_NEK2_1	103	108	PF00069	0.538
MOD_NEK2_2	75	80	PF00069	0.316
MOD_PIKK_1	114	120	PF00454	0.589
MOD_PKA_1	96	102	PF00069	0.533
MOD_PKA_2	127	133	PF00069	0.600
MOD_PKA_2	95	101	PF00069	0.533
MOD_PKB_1	94	102	PF00069	0.534
MOD_ProDKin_1	123	129	PF00069	0.600
MOD_ProDKin_1	133	139	PF00069	0.602
TRG_DiLeu_BaEn_1	38	43	PF01217	0.349
TRG_DiLeu_LyEn_5	38	43	PF01217	0.349
TRG_ENDOCYTIC_2	28	31	PF00928	0.330
TRG_ENDOCYTIC_2	58	61	PF00928	0.199
TRG_ENDOCYTIC_2	82	85	PF00928	0.509
TRG_ER_diArg_1	82	84	PF00400	0.511
TRG_ER_diArg_1	94	97	PF00400	0.542
TRG_NLS_Bipartite_1	96	115	PF00514	0.547