LeishMANIAdb
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Transcriptional regulator

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transcriptional regulator
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H6M1_LEIDO
TriTrypDb:
LdCL_120013600 , LdCL_120014100 , LdCL_120014600 , LdCL_120015100 , LdCL_120015600 , LdCL_120016100 , LdCL_120016600 , LdCL_120017100 , LdCL_120017600 , LdCL_120017700
Length:
155

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H6M1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6M1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 148 150 PF00675 0.575
CLV_PCSK_KEX2_1 148 150 PF00082 0.575
CLV_PCSK_PC7_1 144 150 PF00082 0.568
CLV_PCSK_SKI1_1 15 19 PF00082 0.447
DEG_APCC_DBOX_1 14 22 PF00400 0.441
DOC_CKS1_1 33 38 PF01111 0.531
DOC_CYCLIN_yCln2_LP_2 38 44 PF00134 0.532
DOC_MAPK_gen_1 12 20 PF00069 0.446
DOC_USP7_MATH_1 42 46 PF00917 0.526
DOC_USP7_MATH_1 71 75 PF00917 0.520
DOC_WW_Pin1_4 32 37 PF00397 0.532
DOC_WW_Pin1_4 43 48 PF00397 0.469
DOC_WW_Pin1_4 82 87 PF00397 0.483
LIG_14-3-3_CanoR_1 106 112 PF00244 0.494
LIG_CtBP_PxDLS_1 86 90 PF00389 0.479
LIG_eIF4E_1 43 49 PF01652 0.514
LIG_EVH1_2 57 61 PF00568 0.516
LIG_FHA_1 108 114 PF00498 0.433
LIG_FHA_1 33 39 PF00498 0.535
LIG_FHA_2 83 89 PF00498 0.481
LIG_LIR_Gen_1 88 98 PF02991 0.522
LIG_LIR_Nem_3 88 94 PF02991 0.488
LIG_NRBOX 93 99 PF00104 0.494
LIG_OCRL_FandH_1 90 102 PF00620 0.490
LIG_Pex14_2 61 65 PF04695 0.517
LIG_SH3_3 19 25 PF00018 0.474
LIG_SH3_3 27 33 PF00018 0.515
LIG_SUMO_SIM_par_1 85 90 PF11976 0.475
MOD_Cter_Amidation 146 149 PF01082 0.573
MOD_DYRK1A_RPxSP_1 32 36 PF00069 0.532
MOD_GlcNHglycan 125 128 PF01048 0.587
MOD_GlcNHglycan 58 61 PF01048 0.520
MOD_GlcNHglycan 91 94 PF01048 0.490
MOD_GSK3_1 123 130 PF00069 0.541
MOD_NEK2_1 123 128 PF00069 0.531
MOD_NEK2_1 61 66 PF00069 0.531
MOD_NEK2_1 87 92 PF00069 0.533
MOD_NMyristoyl 1 7 PF02799 0.439
MOD_PKA_2 127 133 PF00069 0.537
MOD_PKB_1 32 40 PF00069 0.533
MOD_Plk_1 87 93 PF00069 0.487
MOD_ProDKin_1 32 38 PF00069 0.533
MOD_ProDKin_1 43 49 PF00069 0.463
MOD_ProDKin_1 82 88 PF00069 0.485
TRG_DiLeu_BaLyEn_6 44 49 PF01217 0.479
TRG_ER_diArg_1 151 154 PF00400 0.577

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8I9B7 Leishmania donovani 96% 100%
A0A3S5H6L4 Leishmania donovani 98% 100%
A0A3S7WRZ5 Leishmania donovani 99% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS