Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S5H6K9_LEIDO

TriTrypDb:

LdBPK_120460.1 , LdCL_120010200 , LDHU3_12.0670

Length:

1035

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H6K9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6K9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	247	251	PF00656	0.654
CLV_C14_Caspase3-7	603	607	PF00656	0.768
CLV_C14_Caspase3-7	703	707	PF00656	0.633
CLV_NRD_NRD_1	1013	1015	PF00675	0.755
CLV_NRD_NRD_1	367	369	PF00675	0.744
CLV_NRD_NRD_1	390	392	PF00675	0.776
CLV_NRD_NRD_1	471	473	PF00675	0.793
CLV_NRD_NRD_1	496	498	PF00675	0.743
CLV_NRD_NRD_1	538	540	PF00675	0.799
CLV_NRD_NRD_1	67	69	PF00675	0.684
CLV_NRD_NRD_1	680	682	PF00675	0.732
CLV_NRD_NRD_1	701	703	PF00675	0.721
CLV_NRD_NRD_1	839	841	PF00675	0.779
CLV_NRD_NRD_1	859	861	PF00675	0.492
CLV_PCSK_KEX2_1	1013	1015	PF00082	0.771
CLV_PCSK_KEX2_1	367	369	PF00082	0.744
CLV_PCSK_KEX2_1	470	472	PF00082	0.793
CLV_PCSK_KEX2_1	496	498	PF00082	0.743
CLV_PCSK_KEX2_1	537	539	PF00082	0.802
CLV_PCSK_KEX2_1	700	702	PF00082	0.723
CLV_PCSK_KEX2_1	839	841	PF00082	0.779
CLV_PCSK_PC7_1	466	472	PF00082	0.798
CLV_PCSK_PC7_1	835	841	PF00082	0.643
CLV_PCSK_SKI1_1	180	184	PF00082	0.845
CLV_PCSK_SKI1_1	441	445	PF00082	0.592
CLV_PCSK_SKI1_1	513	517	PF00082	0.733
CLV_PCSK_SKI1_1	645	649	PF00082	0.749
CLV_PCSK_SKI1_1	68	72	PF00082	0.701
DEG_APCC_DBOX_1	179	187	PF00400	0.841
DEG_APCC_DBOX_1	258	266	PF00400	0.815
DEG_SPOP_SBC_1	197	201	PF00917	0.686
DEG_SPOP_SBC_1	326	330	PF00917	0.724
DEG_SPOP_SBC_1	481	485	PF00917	0.775
DEG_SPOP_SBC_1	619	623	PF00917	0.608
DEG_SPOP_SBC_1	647	651	PF00917	0.756
DEG_SPOP_SBC_1	727	731	PF00917	0.633
DEG_SPOP_SBC_1	978	982	PF00917	0.620
DOC_ANK_TNKS_1	204	211	PF00023	0.686
DOC_CKS1_1	1	6	PF01111	0.704
DOC_CKS1_1	237	242	PF01111	0.776
DOC_CYCLIN_RxL_1	177	185	PF00134	0.765
DOC_CYCLIN_yCln2_LP_2	1023	1029	PF00134	0.673
DOC_CYCLIN_yCln2_LP_2	394	400	PF00134	0.661
DOC_CYCLIN_yCln2_LP_2	443	449	PF00134	0.710
DOC_CYCLIN_yCln2_LP_2	455	461	PF00134	0.598
DOC_CYCLIN_yCln2_LP_2	897	903	PF00134	0.616
DOC_MAPK_MEF2A_6	303	310	PF00069	0.718
DOC_MAPK_MEF2A_6	399	406	PF00069	0.758
DOC_MAPK_MEF2A_6	562	571	PF00069	0.731
DOC_MAPK_MEF2A_6	90	99	PF00069	0.677
DOC_MAPK_NFAT4_5	303	311	PF00069	0.718
DOC_PP2B_LxvP_1	394	397	PF13499	0.617
DOC_PP2B_LxvP_1	422	425	PF13499	0.772
DOC_PP2B_LxvP_1	459	462	PF13499	0.744
DOC_PP2B_LxvP_1	970	973	PF13499	0.729
DOC_PP4_FxxP_1	59	62	PF00568	0.692
DOC_PP4_MxPP_1	241	244	PF00568	0.758
DOC_USP7_MATH_1	1003	1007	PF00917	0.653
DOC_USP7_MATH_1	117	121	PF00917	0.748
DOC_USP7_MATH_1	161	165	PF00917	0.756
DOC_USP7_MATH_1	197	201	PF00917	0.784
DOC_USP7_MATH_1	32	36	PF00917	0.792
DOC_USP7_MATH_1	326	330	PF00917	0.763
DOC_USP7_MATH_1	507	511	PF00917	0.669
DOC_USP7_MATH_1	561	565	PF00917	0.722
DOC_USP7_MATH_1	567	571	PF00917	0.659
DOC_USP7_MATH_1	600	604	PF00917	0.776
DOC_USP7_MATH_1	786	790	PF00917	0.614
DOC_USP7_MATH_1	808	812	PF00917	0.559
DOC_USP7_MATH_1	852	856	PF00917	0.730
DOC_USP7_MATH_1	884	888	PF00917	0.708
DOC_USP7_MATH_1	920	924	PF00917	0.742
DOC_USP7_MATH_1	978	982	PF00917	0.693
DOC_USP7_MATH_2	409	415	PF00917	0.722
DOC_WW_Pin1_4	107	112	PF00397	0.846
DOC_WW_Pin1_4	118	123	PF00397	0.673
DOC_WW_Pin1_4	129	134	PF00397	0.675
DOC_WW_Pin1_4	144	149	PF00397	0.678
DOC_WW_Pin1_4	229	234	PF00397	0.731
DOC_WW_Pin1_4	236	241	PF00397	0.721
DOC_WW_Pin1_4	248	253	PF00397	0.575
DOC_WW_Pin1_4	277	282	PF00397	0.716
DOC_WW_Pin1_4	329	334	PF00397	0.716
DOC_WW_Pin1_4	454	459	PF00397	0.715
DOC_WW_Pin1_4	548	553	PF00397	0.808
DOC_WW_Pin1_4	591	596	PF00397	0.761
DOC_WW_Pin1_4	755	760	PF00397	0.752
DOC_WW_Pin1_4	860	865	PF00397	0.697
DOC_WW_Pin1_4	882	887	PF00397	0.672
DOC_WW_Pin1_4	909	914	PF00397	0.666
DOC_WW_Pin1_4	982	987	PF00397	0.856
LIG_14-3-3_CanoR_1	116	122	PF00244	0.740
LIG_14-3-3_CanoR_1	341	347	PF00244	0.835
LIG_14-3-3_CanoR_1	439	444	PF00244	0.727
LIG_14-3-3_CanoR_1	75	85	PF00244	0.709
LIG_APCC_ABBA_1	788	793	PF00400	0.756
LIG_APCC_ABBA_1	957	962	PF00400	0.726
LIG_BRCT_BRCA1_1	120	124	PF00533	0.779
LIG_BRCT_BRCA1_1	35	39	PF00533	0.687
LIG_Clathr_ClatBox_1	639	643	PF01394	0.663
LIG_CSL_BTD_1	157	160	PF09270	0.629
LIG_CtBP_PxDLS_1	595	599	PF00389	0.631
LIG_deltaCOP1_diTrp_1	155	158	PF00928	0.642
LIG_FHA_1	130	136	PF00498	0.781
LIG_FHA_1	15	21	PF00498	0.738
LIG_FHA_1	209	215	PF00498	0.774
LIG_FHA_1	267	273	PF00498	0.773
LIG_FHA_1	330	336	PF00498	0.748
LIG_FHA_1	378	384	PF00498	0.757
LIG_FHA_1	438	444	PF00498	0.744
LIG_FHA_1	477	483	PF00498	0.755
LIG_FHA_1	619	625	PF00498	0.593
LIG_FHA_1	648	654	PF00498	0.767
LIG_FHA_1	740	746	PF00498	0.634
LIG_FHA_1	783	789	PF00498	0.643
LIG_FHA_1	822	828	PF00498	0.722
LIG_FHA_1	871	877	PF00498	0.726
LIG_FHA_1	92	98	PF00498	0.747
LIG_FHA_1	961	967	PF00498	0.627
LIG_FHA_2	125	131	PF00498	0.765
LIG_FHA_2	150	156	PF00498	0.686
LIG_FHA_2	514	520	PF00498	0.630
LIG_FHA_2	620	626	PF00498	0.732
LIG_LIR_Apic_2	155	161	PF02991	0.630
LIG_LIR_Apic_2	58	62	PF02991	0.690
LIG_LIR_Gen_1	155	163	PF02991	0.727
LIG_LIR_Gen_1	553	561	PF02991	0.659
LIG_LIR_Gen_1	873	882	PF02991	0.637
LIG_LIR_Nem_3	101	106	PF02991	0.729
LIG_LIR_Nem_3	155	159	PF02991	0.740
LIG_LIR_Nem_3	553	559	PF02991	0.670
LIG_LIR_Nem_3	58	63	PF02991	0.765
LIG_LIR_Nem_3	760	765	PF02991	0.542
LIG_LIR_Nem_3	84	89	PF02991	0.681
LIG_LIR_Nem_3	873	878	PF02991	0.632
LIG_MYND_1	168	172	PF01753	0.664
LIG_MYND_1	596	600	PF01753	0.765
LIG_Pex14_2	301	305	PF04695	0.592
LIG_SH2_CRK	635	639	PF00017	0.768
LIG_SH2_CRK	86	90	PF00017	0.680
LIG_SH2_STAP1	635	639	PF00017	0.729
LIG_SH2_STAP1	960	964	PF00017	0.685
LIG_SH2_STAT5	106	109	PF00017	0.508
LIG_SH2_STAT5	86	89	PF00017	0.683
LIG_SH2_STAT5	865	868	PF00017	0.726
LIG_SH2_STAT5	875	878	PF00017	0.609
LIG_SH3_2	111	116	PF14604	0.736
LIG_SH3_2	148	153	PF14604	0.675
LIG_SH3_2	458	463	PF14604	0.675
LIG_SH3_2	584	589	PF14604	0.790
LIG_SH3_3	1009	1015	PF00018	0.751
LIG_SH3_3	108	114	PF00018	0.814
LIG_SH3_3	145	151	PF00018	0.706
LIG_SH3_3	166	172	PF00018	0.627
LIG_SH3_3	231	237	PF00018	0.804
LIG_SH3_3	239	245	PF00018	0.732
LIG_SH3_3	455	461	PF00018	0.750
LIG_SH3_3	581	587	PF00018	0.781
LIG_SH3_3	590	596	PF00018	0.657
LIG_SH3_3	667	673	PF00018	0.627
LIG_SH3_3	705	711	PF00018	0.729
LIG_SH3_3	717	723	PF00018	0.589
LIG_SH3_3	749	755	PF00018	0.727
LIG_SH3_3	910	916	PF00018	0.756
LIG_SUMO_SIM_anti_2	94	99	PF11976	0.675
LIG_SUMO_SIM_par_1	166	173	PF11976	0.660
LIG_SUMO_SIM_par_1	785	793	PF11976	0.750
LIG_SUMO_SIM_par_1	96	102	PF11976	0.688
LIG_UBA3_1	455	463	PF00899	0.622
LIG_WW_3	113	117	PF00397	0.737
LIG_WW_3	232	236	PF00397	0.675
LIG_WW_3	559	563	PF00397	0.750
MOD_CDC14_SPxK_1	232	235	PF00782	0.678
MOD_CDC14_SPxK_1	460	463	PF00782	0.681
MOD_CDC14_SPxK_1	758	761	PF00782	0.755
MOD_CDK_SPxK_1	229	235	PF00069	0.673
MOD_CDK_SPxK_1	457	463	PF00069	0.670
MOD_CDK_SPxK_1	755	761	PF00069	0.754
MOD_CK1_1	1006	1012	PF00069	0.722
MOD_CK1_1	144	150	PF00069	0.785
MOD_CK1_1	173	179	PF00069	0.837
MOD_CK1_1	248	254	PF00069	0.741
MOD_CK1_1	289	295	PF00069	0.715
MOD_CK1_1	329	335	PF00069	0.740
MOD_CK1_1	414	420	PF00069	0.773
MOD_CK1_1	427	433	PF00069	0.616
MOD_CK1_1	457	463	PF00069	0.715
MOD_CK1_1	476	482	PF00069	0.600
MOD_CK1_1	548	554	PF00069	0.806
MOD_CK1_1	686	692	PF00069	0.714
MOD_CK1_1	782	788	PF00069	0.691
MOD_CK1_1	789	795	PF00069	0.672
MOD_CK1_1	811	817	PF00069	0.695
MOD_CK1_1	84	90	PF00069	0.680
MOD_CK1_1	91	97	PF00069	0.636
MOD_CK1_1	943	949	PF00069	0.748
MOD_CK1_1	982	988	PF00069	0.732
MOD_CK2_1	124	130	PF00069	0.768
MOD_CK2_1	513	519	PF00069	0.631
MOD_Cter_Amidation	389	392	PF01082	0.777
MOD_GlcNHglycan	163	166	PF01048	0.757
MOD_GlcNHglycan	172	175	PF01048	0.647
MOD_GlcNHglycan	188	191	PF01048	0.764
MOD_GlcNHglycan	229	232	PF01048	0.766
MOD_GlcNHglycan	247	250	PF01048	0.566
MOD_GlcNHglycan	288	291	PF01048	0.730
MOD_GlcNHglycan	329	332	PF01048	0.786
MOD_GlcNHglycan	418	421	PF01048	0.810
MOD_GlcNHglycan	426	429	PF01048	0.732
MOD_GlcNHglycan	475	478	PF01048	0.846
MOD_GlcNHglycan	498	501	PF01048	0.718
MOD_GlcNHglycan	52	55	PF01048	0.778
MOD_GlcNHglycan	531	534	PF01048	0.779
MOD_GlcNHglycan	563	566	PF01048	0.803
MOD_GlcNHglycan	655	658	PF01048	0.771
MOD_GlcNHglycan	733	736	PF01048	0.800
MOD_GlcNHglycan	754	758	PF01048	0.757
MOD_GlcNHglycan	808	811	PF01048	0.723
MOD_GlcNHglycan	854	857	PF01048	0.715
MOD_GlcNHglycan	886	889	PF01048	0.650
MOD_GlcNHglycan	893	896	PF01048	0.704
MOD_GlcNHglycan	9	12	PF01048	0.680
MOD_GSK3_1	125	132	PF00069	0.775
MOD_GSK3_1	182	189	PF00069	0.762
MOD_GSK3_1	325	332	PF00069	0.800
MOD_GSK3_1	350	357	PF00069	0.651
MOD_GSK3_1	374	381	PF00069	0.750
MOD_GSK3_1	407	414	PF00069	0.829
MOD_GSK3_1	416	423	PF00069	0.698
MOD_GSK3_1	471	478	PF00069	0.784
MOD_GSK3_1	481	488	PF00069	0.648
MOD_GSK3_1	492	499	PF00069	0.593
MOD_GSK3_1	550	557	PF00069	0.672
MOD_GSK3_1	587	594	PF00069	0.760
MOD_GSK3_1	641	648	PF00069	0.823
MOD_GSK3_1	649	656	PF00069	0.709
MOD_GSK3_1	683	690	PF00069	0.732
MOD_GSK3_1	727	734	PF00069	0.652
MOD_GSK3_1	736	743	PF00069	0.647
MOD_GSK3_1	753	760	PF00069	0.656
MOD_GSK3_1	77	84	PF00069	0.710
MOD_GSK3_1	775	782	PF00069	0.744
MOD_GSK3_1	847	854	PF00069	0.606
MOD_GSK3_1	880	887	PF00069	0.734
MOD_GSK3_1	939	946	PF00069	0.763
MOD_GSK3_1	978	985	PF00069	0.736
MOD_LATS_1	437	443	PF00433	0.576
MOD_LATS_1	494	500	PF00433	0.738
MOD_N-GLC_1	736	741	PF02516	0.635
MOD_N-GLC_1	940	945	PF02516	0.763
MOD_NEK2_1	124	129	PF00069	0.720
MOD_NEK2_1	182	187	PF00069	0.762
MOD_NEK2_1	588	593	PF00069	0.759
MOD_NEK2_1	685	690	PF00069	0.702
MOD_NEK2_1	7	12	PF00069	0.652
MOD_NEK2_1	939	944	PF00069	0.767
MOD_NEK2_1	979	984	PF00069	0.671
MOD_NEK2_2	402	407	PF00069	0.754
MOD_NEK2_2	567	572	PF00069	0.641
MOD_NEK2_2	786	791	PF00069	0.751
MOD_NEK2_2	955	960	PF00069	0.632
MOD_PIKK_1	811	817	PF00454	0.640
MOD_PIKK_1	834	840	PF00454	0.781
MOD_PIKK_1	940	946	PF00454	0.759
MOD_PK_1	1004	1010	PF00069	0.760
MOD_PK_1	81	87	PF00069	0.694
MOD_PKA_1	470	476	PF00069	0.787
MOD_PKA_1	496	502	PF00069	0.738
MOD_PKA_2	115	121	PF00069	0.737
MOD_PKA_2	381	387	PF00069	0.774
MOD_PKA_2	470	476	PF00069	0.845
MOD_PKA_2	49	55	PF00069	0.691
MOD_PKA_2	496	502	PF00069	0.843
MOD_PKA_2	561	567	PF00069	0.759
MOD_PKA_2	834	840	PF00069	0.674
MOD_PKA_2	904	910	PF00069	0.755
MOD_PKB_1	470	478	PF00069	0.785
MOD_Plk_1	154	160	PF00069	0.635
MOD_Plk_1	260	266	PF00069	0.746
MOD_Plk_1	354	360	PF00069	0.661
MOD_Plk_1	567	573	PF00069	0.641
MOD_Plk_1	619	625	PF00069	0.729
MOD_Plk_1	739	745	PF00069	0.726
MOD_Plk_2-3	620	626	PF00069	0.732
MOD_Plk_4	402	408	PF00069	0.754
MOD_Plk_4	439	445	PF00069	0.736
MOD_Plk_4	55	61	PF00069	0.704
MOD_Plk_4	567	573	PF00069	0.641
MOD_Plk_4	594	600	PF00069	0.624
MOD_Plk_4	649	655	PF00069	0.766
MOD_Plk_4	740	746	PF00069	0.677
MOD_Plk_4	81	87	PF00069	0.694
MOD_Plk_4	814	820	PF00069	0.734
MOD_Plk_4	904	910	PF00069	0.755
MOD_Plk_4	93	99	PF00069	0.754
MOD_Plk_4	955	961	PF00069	0.727
MOD_ProDKin_1	107	113	PF00069	0.848
MOD_ProDKin_1	118	124	PF00069	0.674
MOD_ProDKin_1	129	135	PF00069	0.676
MOD_ProDKin_1	144	150	PF00069	0.675
MOD_ProDKin_1	229	235	PF00069	0.736
MOD_ProDKin_1	236	242	PF00069	0.719
MOD_ProDKin_1	248	254	PF00069	0.574
MOD_ProDKin_1	277	283	PF00069	0.718
MOD_ProDKin_1	329	335	PF00069	0.717
MOD_ProDKin_1	454	460	PF00069	0.719
MOD_ProDKin_1	548	554	PF00069	0.808
MOD_ProDKin_1	591	597	PF00069	0.761
MOD_ProDKin_1	755	761	PF00069	0.754
MOD_ProDKin_1	860	866	PF00069	0.695
MOD_ProDKin_1	882	888	PF00069	0.673
MOD_ProDKin_1	909	915	PF00069	0.667
MOD_ProDKin_1	982	988	PF00069	0.858
MOD_SUMO_rev_2	641	647	PF00179	0.746
TRG_DiLeu_BaEn_1	166	171	PF01217	0.633
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.763
TRG_ENDOCYTIC_2	556	559	PF00928	0.675
TRG_ENDOCYTIC_2	635	638	PF00928	0.765
TRG_ENDOCYTIC_2	86	89	PF00928	0.683
TRG_ENDOCYTIC_2	875	878	PF00928	0.638
TRG_ER_diArg_1	1012	1014	PF00400	0.753
TRG_ER_diArg_1	470	472	PF00400	0.793
TRG_ER_diArg_1	496	498	PF00400	0.743
TRG_ER_diArg_1	537	539	PF00400	0.802
TRG_ER_diArg_1	700	702	PF00400	0.750
TRG_Pf-PMV_PEXEL_1	1014	1018	PF00026	0.760
TRG_Pf-PMV_PEXEL_1	520	525	PF00026	0.713

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AGD8	Leishmania infantum	99%	100%
E9ANX8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	95%
Q4QGP2	Leishmania major	84%	100%