LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S5H6K7_LEIDO
TriTrypDb:
LdBPK_120360.1 * , LdCL_120009200 , LDHU3_12.0540
Length:
410

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H6K7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6K7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 48 52 PF00656 0.710
CLV_NRD_NRD_1 101 103 PF00675 0.606
CLV_NRD_NRD_1 138 140 PF00675 0.621
CLV_NRD_NRD_1 276 278 PF00675 0.729
CLV_PCSK_KEX2_1 276 278 PF00082 0.729
CLV_PCSK_SKI1_1 184 188 PF00082 0.803
CLV_PCSK_SKI1_1 296 300 PF00082 0.683
DEG_Nend_Nbox_1 1 3 PF02207 0.700
DEG_ODPH_VHL_1 176 188 PF01847 0.728
DEG_SCF_FBW7_1 396 402 PF00400 0.712
DEG_SCF_FBW7_2 348 355 PF00400 0.732
DEG_SPOP_SBC_1 16 20 PF00917 0.761
DOC_CKS1_1 396 401 PF01111 0.714
DOC_CYCLIN_yCln2_LP_2 388 394 PF00134 0.767
DOC_PP1_RVXF_1 236 243 PF00149 0.754
DOC_PP2B_LxvP_1 106 109 PF13499 0.503
DOC_USP7_MATH_1 143 147 PF00917 0.710
DOC_USP7_MATH_1 16 20 PF00917 0.643
DOC_USP7_MATH_1 266 270 PF00917 0.778
DOC_USP7_MATH_1 381 385 PF00917 0.736
DOC_WW_Pin1_4 107 112 PF00397 0.645
DOC_WW_Pin1_4 129 134 PF00397 0.826
DOC_WW_Pin1_4 155 160 PF00397 0.633
DOC_WW_Pin1_4 197 202 PF00397 0.839
DOC_WW_Pin1_4 250 255 PF00397 0.686
DOC_WW_Pin1_4 301 306 PF00397 0.819
DOC_WW_Pin1_4 348 353 PF00397 0.811
DOC_WW_Pin1_4 382 387 PF00397 0.760
DOC_WW_Pin1_4 395 400 PF00397 0.719
DOC_WW_Pin1_4 85 90 PF00397 0.718
LIG_14-3-3_CanoR_1 197 201 PF00244 0.800
LIG_14-3-3_CanoR_1 25 29 PF00244 0.659
LIG_14-3-3_CanoR_1 72 81 PF00244 0.712
LIG_AP_GAE_1 93 99 PF02883 0.695
LIG_BIR_III_2 282 286 PF00653 0.761
LIG_BIR_III_4 51 55 PF00653 0.672
LIG_BRCT_BRCA1_1 324 328 PF00533 0.770
LIG_Clathr_ClatBox_1 8 12 PF01394 0.717
LIG_EH_1 325 329 PF12763 0.671
LIG_eIF4E_1 180 186 PF01652 0.665
LIG_eIF4E_1 361 367 PF01652 0.584
LIG_FHA_1 152 158 PF00498 0.724
LIG_FHA_1 221 227 PF00498 0.661
LIG_FHA_1 310 316 PF00498 0.710
LIG_FHA_1 387 393 PF00498 0.764
LIG_FHA_2 368 374 PF00498 0.791
LIG_FHA_2 46 52 PF00498 0.675
LIG_IRF3_LxIS_1 56 63 PF10401 0.767
LIG_LIR_Gen_1 93 104 PF02991 0.771
LIG_LIR_Nem_3 93 99 PF02991 0.772
LIG_NRBOX 4 10 PF00104 0.695
LIG_RPA_C_Fungi 67 79 PF08784 0.683
LIG_SH2_CRK 86 90 PF00017 0.666
LIG_SH2_GRB2like 150 153 PF00017 0.751
LIG_SH2_STAT5 361 364 PF00017 0.685
LIG_SH3_3 130 136 PF00018 0.744
LIG_SH3_3 227 233 PF00018 0.750
LIG_SH3_3 302 308 PF00018 0.824
LIG_SH3_3 318 324 PF00018 0.552
LIG_SUMO_SIM_anti_2 181 190 PF11976 0.723
LIG_SUMO_SIM_par_1 153 158 PF11976 0.727
LIG_SUMO_SIM_par_1 181 190 PF11976 0.723
LIG_SUMO_SIM_par_1 365 371 PF11976 0.698
LIG_SUMO_SIM_par_1 6 12 PF11976 0.708
LIG_TRAF2_1 352 355 PF00917 0.726
LIG_WW_3 79 83 PF00397 0.742
MOD_CDC14_SPxK_1 200 203 PF00782 0.842
MOD_CDK_SPK_2 85 90 PF00069 0.709
MOD_CDK_SPxK_1 197 203 PF00069 0.841
MOD_CDK_SPxK_1 395 401 PF00069 0.619
MOD_CDK_SPxxK_3 132 139 PF00069 0.604
MOD_CK1_1 135 141 PF00069 0.724
MOD_CK1_1 18 24 PF00069 0.666
MOD_CK1_1 199 205 PF00069 0.673
MOD_CK1_1 26 32 PF00069 0.676
MOD_CK2_1 122 128 PF00069 0.723
MOD_CK2_1 266 272 PF00069 0.699
MOD_CK2_1 70 76 PF00069 0.807
MOD_GlcNHglycan 194 197 PF01048 0.677
MOD_GlcNHglycan 220 223 PF01048 0.697
MOD_GlcNHglycan 258 261 PF01048 0.780
MOD_GlcNHglycan 268 271 PF01048 0.650
MOD_GlcNHglycan 28 31 PF01048 0.714
MOD_GlcNHglycan 355 359 PF01048 0.650
MOD_GlcNHglycan 72 75 PF01048 0.684
MOD_GSK3_1 15 22 PF00069 0.807
MOD_GSK3_1 151 158 PF00069 0.754
MOD_GSK3_1 168 175 PF00069 0.553
MOD_GSK3_1 192 199 PF00069 0.703
MOD_GSK3_1 24 31 PF00069 0.681
MOD_GSK3_1 382 389 PF00069 0.826
MOD_GSK3_1 395 402 PF00069 0.714
MOD_GSK3_1 66 73 PF00069 0.725
MOD_N-GLC_1 151 156 PF02516 0.716
MOD_N-GLC_1 218 223 PF02516 0.656
MOD_NEK2_1 121 126 PF00069 0.784
MOD_NEK2_1 299 304 PF00069 0.831
MOD_NEK2_1 328 333 PF00069 0.707
MOD_NEK2_1 60 65 PF00069 0.764
MOD_NEK2_1 70 75 PF00069 0.640
MOD_NEK2_1 92 97 PF00069 0.695
MOD_NEK2_2 143 148 PF00069 0.691
MOD_PIKK_1 231 237 PF00454 0.780
MOD_PK_1 341 347 PF00069 0.604
MOD_PKA_2 196 202 PF00069 0.797
MOD_PKA_2 24 30 PF00069 0.658
MOD_Plk_1 151 157 PF00069 0.681
MOD_Plk_1 92 98 PF00069 0.694
MOD_Plk_4 3 9 PF00069 0.639
MOD_ProDKin_1 107 113 PF00069 0.647
MOD_ProDKin_1 129 135 PF00069 0.827
MOD_ProDKin_1 155 161 PF00069 0.648
MOD_ProDKin_1 197 203 PF00069 0.841
MOD_ProDKin_1 250 256 PF00069 0.688
MOD_ProDKin_1 301 307 PF00069 0.819
MOD_ProDKin_1 348 354 PF00069 0.812
MOD_ProDKin_1 382 388 PF00069 0.764
MOD_ProDKin_1 395 401 PF00069 0.716
MOD_ProDKin_1 85 91 PF00069 0.715
TRG_DiLeu_BaEn_1 181 186 PF01217 0.802
TRG_DiLeu_LyEn_5 181 186 PF01217 0.802
TRG_ER_diArg_1 236 239 PF00400 0.748
TRG_Pf-PMV_PEXEL_1 238 243 PF00026 0.757
TRG_Pf-PMV_PEXEL_1 90 94 PF00026 0.704

Homologs

Protein Taxonomy Sequence identity Coverage
A4H6V6 Leishmania braziliensis 62% 97%
E9AGC8 Leishmania infantum 99% 100%
E9ANW8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 95%
Q4QGQ2 Leishmania major 89% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS