Ribosomal protein L24e family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L24, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H6J2_LEIDO

TriTrypDb:

LdBPK_110900.1 , LdCL_110014500 , LDHU3_11.1120

Length:

190

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S ribosomal L24

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	11
GO:0043226	organelle	2	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11
GO:0005730	nucleolus	5	1

Expansion

Sequence features

A0A3S5H6J2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6J2

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	1
GO:0022613	ribonucleoprotein complex biogenesis	4	1
GO:0042273	ribosomal large subunit biogenesis	5	1
GO:0044085	cellular component biogenesis	3	1
GO:0071840	cellular component organization or biogenesis	2	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.479
CLV_NRD_NRD_1	110	112	PF00675	0.419
CLV_NRD_NRD_1	161	163	PF00675	0.495
CLV_NRD_NRD_1	36	38	PF00675	0.238
CLV_NRD_NRD_1	55	57	PF00675	0.243
CLV_NRD_NRD_1	74	76	PF00675	0.445
CLV_PCSK_KEX2_1	102	104	PF00082	0.233
CLV_PCSK_KEX2_1	110	112	PF00082	0.427
CLV_PCSK_KEX2_1	160	162	PF00082	0.506
CLV_PCSK_KEX2_1	167	169	PF00082	0.489
CLV_PCSK_KEX2_1	43	45	PF00082	0.243
CLV_PCSK_KEX2_1	74	76	PF00082	0.445
CLV_PCSK_KEX2_1	94	96	PF00082	0.231
CLV_PCSK_PC1ET2_1	160	162	PF00082	0.526
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.465
CLV_PCSK_PC1ET2_1	43	45	PF00082	0.243
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.417
CLV_PCSK_SKI1_1	157	161	PF00082	0.594
CLV_PCSK_SKI1_1	185	189	PF00082	0.646
CLV_PCSK_SKI1_1	83	87	PF00082	0.404
CLV_PCSK_SKI1_1	91	95	PF00082	0.423
DEG_APCC_DBOX_1	143	151	PF00400	0.427
DEG_Nend_UBRbox_1	1	4	PF02207	0.443
DOC_CYCLIN_RxL_1	80	89	PF00134	0.415
DOC_MAPK_gen_1	142	150	PF00069	0.431
DOC_MAPK_gen_1	43	49	PF00069	0.443
DOC_PP1_RVXF_1	46	52	PF00149	0.443
DOC_USP7_MATH_1	183	187	PF00917	0.645
DOC_USP7_MATH_1	64	68	PF00917	0.545
DOC_USP7_UBL2_3	167	171	PF12436	0.464
DOC_USP7_UBL2_3	53	57	PF12436	0.443
DOC_USP7_UBL2_3	94	98	PF12436	0.442
LIG_FHA_1	87	93	PF00498	0.407
LIG_Pex14_1	51	55	PF04695	0.443
LIG_SH3_3	9	15	PF00018	0.443
MOD_CK1_1	7	13	PF00069	0.523
MOD_GlcNHglycan	124	127	PF01048	0.508
MOD_GlcNHglycan	181	184	PF01048	0.630
MOD_GlcNHglycan	185	188	PF01048	0.648
MOD_GlcNHglycan	9	12	PF01048	0.301
MOD_GSK3_1	179	186	PF00069	0.553
MOD_N-GLC_2	24	26	PF02516	0.243
MOD_NEK2_1	31	36	PF00069	0.421
MOD_NEK2_1	49	54	PF00069	0.443
MOD_NEK2_1	86	91	PF00069	0.391
MOD_NEK2_2	51	56	PF00069	0.443
MOD_Plk_1	65	71	PF00069	0.423
MOD_SUMO_rev_2	153	159	PF00179	0.575
TRG_ER_diArg_1	110	112	PF00400	0.508
TRG_Pf-PMV_PEXEL_1	83	88	PF00026	0.431

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXI2	Leptomonas seymouri	93%	100%
A0A1X0NVE9	Trypanosomatidae	80%	99%
A0A3R7KPE4	Trypanosoma rangeli	79%	100%
A4H6L6	Leishmania braziliensis	94%	100%
A4HUZ9	Leishmania infantum	100%	100%
D0A7E9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	99%
E9ANN4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
O22165	Arabidopsis thaliana	47%	100%
Q07915	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	56%	95%
Q10353	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	49%	99%
Q3SZ12	Bos taurus	60%	100%
Q4QGY9	Leishmania major	97%	100%
Q5RF04	Pongo abelii	59%	100%
Q6BH34	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	51%	94%
Q6CF69	Yarrowia lipolytica (strain CLIB 122 / E 150)	54%	100%
Q6P6G7	Rattus norvegicus	61%	100%
Q7ZTZ2	Danio rerio	60%	100%
Q86B05	Dictyostelium discoideum	56%	100%
Q8SSF6	Encephalitozoon cuniculi (strain GB-M1)	39%	100%
Q99L28	Mus musculus	60%	100%
Q9UHA3	Homo sapiens	60%	100%
Q9VGN9	Drosophila melanogaster	51%	99%
V5BWK7	Trypanosoma cruzi	80%	99%