Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S5H6I5_LEIDO

TriTrypDb:

LdBPK_110480.1 , LdCL_110009650

Length:

457

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H6I5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6I5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	222	226	PF00656	0.389
CLV_NRD_NRD_1	26	28	PF00675	0.644
CLV_NRD_NRD_1	356	358	PF00675	0.769
CLV_NRD_NRD_1	439	441	PF00675	0.568
CLV_PCSK_KEX2_1	26	28	PF00082	0.644
CLV_PCSK_KEX2_1	356	358	PF00082	0.780
CLV_PCSK_KEX2_1	439	441	PF00082	0.568
CLV_PCSK_SKI1_1	122	126	PF00082	0.464
CLV_PCSK_SKI1_1	269	273	PF00082	0.630
CLV_PCSK_SKI1_1	440	444	PF00082	0.557
CLV_PCSK_SKI1_1	54	58	PF00082	0.633
DEG_APCC_DBOX_1	268	276	PF00400	0.419
DOC_CDC14_PxL_1	421	429	PF14671	0.539
DOC_CYCLIN_RxL_1	54	65	PF00134	0.469
DOC_CYCLIN_yCln2_LP_2	393	399	PF00134	0.524
DOC_MAPK_gen_1	385	395	PF00069	0.533
DOC_MAPK_gen_1	54	64	PF00069	0.466
DOC_MAPK_MEF2A_6	269	276	PF00069	0.501
DOC_MAPK_MEF2A_6	388	397	PF00069	0.531
DOC_MAPK_MEF2A_6	57	64	PF00069	0.458
DOC_PP1_RVXF_1	267	274	PF00149	0.422
DOC_PP1_RVXF_1	298	304	PF00149	0.433
DOC_PP1_RVXF_1	55	62	PF00149	0.459
DOC_PP2B_LxvP_1	329	332	PF13499	0.507
DOC_PP2B_LxvP_1	393	396	PF13499	0.532
DOC_PP2B_LxvP_1	422	425	PF13499	0.533
DOC_USP7_MATH_1	104	108	PF00917	0.539
DOC_USP7_MATH_1	68	72	PF00917	0.503
DOC_WW_Pin1_4	131	136	PF00397	0.460
DOC_WW_Pin1_4	147	152	PF00397	0.556
DOC_WW_Pin1_4	309	314	PF00397	0.490
DOC_WW_Pin1_4	347	352	PF00397	0.524
DOC_WW_Pin1_4	35	40	PF00397	0.493
DOC_WW_Pin1_4	99	104	PF00397	0.738
LIG_14-3-3_CanoR_1	21	29	PF00244	0.511
LIG_14-3-3_CanoR_1	300	306	PF00244	0.605
LIG_14-3-3_CanoR_1	357	367	PF00244	0.564
LIG_14-3-3_CanoR_1	428	435	PF00244	0.559
LIG_14-3-3_CanoR_1	75	81	PF00244	0.442
LIG_14-3-3_CterR_2	454	457	PF00244	0.562
LIG_APCC_ABBAyCdc20_2	57	63	PF00400	0.475
LIG_BIR_III_2	100	104	PF00653	0.518
LIG_Clathr_ClatBox_1	59	63	PF01394	0.466
LIG_eIF4E_1	141	147	PF01652	0.448
LIG_EVH1_1	422	426	PF00568	0.535
LIG_FHA_1	134	140	PF00498	0.575
LIG_FHA_1	148	154	PF00498	0.450
LIG_FHA_1	156	162	PF00498	0.475
LIG_FHA_1	166	172	PF00498	0.417
LIG_FHA_1	230	236	PF00498	0.509
LIG_FHA_1	263	269	PF00498	0.603
LIG_FHA_1	373	379	PF00498	0.495
LIG_FHA_2	171	177	PF00498	0.477
LIG_FHA_2	180	186	PF00498	0.354
LIG_FHA_2	428	434	PF00498	0.559
LIG_LIR_Gen_1	365	376	PF02991	0.511
LIG_LIR_Gen_1	42	53	PF02991	0.524
LIG_LIR_Nem_3	136	141	PF02991	0.680
LIG_LIR_Nem_3	211	216	PF02991	0.428
LIG_LIR_Nem_3	42	48	PF02991	0.451
LIG_LIR_Nem_3	433	437	PF02991	0.570
LIG_MYND_1	398	402	PF01753	0.516
LIG_NRBOX	263	269	PF00104	0.382
LIG_Pex14_1	286	290	PF04695	0.438
LIG_SH2_CRK	45	49	PF00017	0.491
LIG_SH2_NCK_1	221	225	PF00017	0.380
LIG_SH2_PTP2	52	55	PF00017	0.433
LIG_SH2_STAP1	45	49	PF00017	0.436
LIG_SH2_STAT5	138	141	PF00017	0.438
LIG_SH2_STAT5	367	370	PF00017	0.735
LIG_SH2_STAT5	416	419	PF00017	0.496
LIG_SH2_STAT5	52	55	PF00017	0.478
LIG_SH2_STAT5	96	99	PF00017	0.509
LIG_SH3_2	423	428	PF14604	0.541
LIG_SH3_3	148	154	PF00018	0.486
LIG_SH3_3	211	217	PF00018	0.423
LIG_SH3_3	271	277	PF00018	0.433
LIG_SH3_3	31	37	PF00018	0.685
LIG_SH3_3	395	401	PF00018	0.551
LIG_SH3_3	420	426	PF00018	0.528
LIG_SUMO_SIM_anti_2	182	188	PF11976	0.398
LIG_SUMO_SIM_anti_2	262	268	PF11976	0.379
LIG_SUMO_SIM_par_1	123	131	PF11976	0.484
LIG_SUMO_SIM_par_1	200	207	PF11976	0.447
LIG_TRAF2_1	296	299	PF00917	0.429
LIG_TYR_ITIM	43	48	PF00017	0.466
LIG_TYR_ITIM	50	55	PF00017	0.399
MOD_CDC14_SPxK_1	350	353	PF00782	0.535
MOD_CDK_SPxK_1	347	353	PF00069	0.528
MOD_CK1_1	131	137	PF00069	0.462
MOD_CK1_1	35	41	PF00069	0.511
MOD_CK2_1	123	129	PF00069	0.466
MOD_CK2_1	179	185	PF00069	0.384
MOD_CK2_1	427	433	PF00069	0.555
MOD_GlcNHglycan	106	109	PF01048	0.545
MOD_GlcNHglycan	316	319	PF01048	0.435
MOD_GlcNHglycan	382	385	PF01048	0.668
MOD_GlcNHglycan	65	69	PF01048	0.539
MOD_GSK3_1	165	172	PF00069	0.471
MOD_GSK3_1	17	24	PF00069	0.720
MOD_GSK3_1	175	182	PF00069	0.383
MOD_GSK3_1	28	35	PF00069	0.714
MOD_GSK3_1	343	350	PF00069	0.724
MOD_GSK3_1	64	71	PF00069	0.590
MOD_NEK2_1	116	121	PF00069	0.467
MOD_NEK2_1	170	175	PF00069	0.478
MOD_NEK2_1	191	196	PF00069	0.451
MOD_NEK2_1	204	209	PF00069	0.382
MOD_NEK2_1	372	377	PF00069	0.592
MOD_NEK2_1	427	432	PF00069	0.553
MOD_NEK2_1	444	449	PF00069	0.475
MOD_NEK2_2	229	234	PF00069	0.402
MOD_PIKK_1	133	139	PF00454	0.467
MOD_PIKK_1	155	161	PF00454	0.547
MOD_PIKK_1	163	169	PF00454	0.613
MOD_PIKK_1	427	433	PF00454	0.555
MOD_PKA_2	352	358	PF00069	0.699
MOD_PKA_2	380	386	PF00069	0.519
MOD_PKA_2	427	433	PF00069	0.555
MOD_PKA_2	74	80	PF00069	0.451
MOD_PKB_1	19	27	PF00069	0.502
MOD_PKB_1	30	38	PF00069	0.530
MOD_Plk_1	282	288	PF00069	0.449
MOD_Plk_1	444	450	PF00069	0.555
MOD_Plk_2-3	123	129	PF00069	0.485
MOD_Plk_4	116	122	PF00069	0.502
MOD_Plk_4	175	181	PF00069	0.417
MOD_Plk_4	262	268	PF00069	0.473
MOD_Plk_4	324	330	PF00069	0.563
MOD_Plk_4	363	369	PF00069	0.565
MOD_Plk_4	44	50	PF00069	0.436
MOD_ProDKin_1	131	137	PF00069	0.462
MOD_ProDKin_1	147	153	PF00069	0.551
MOD_ProDKin_1	309	315	PF00069	0.482
MOD_ProDKin_1	347	353	PF00069	0.528
MOD_ProDKin_1	35	41	PF00069	0.486
MOD_ProDKin_1	99	105	PF00069	0.736
TRG_DiLeu_BaEn_1	262	267	PF01217	0.383
TRG_DiLeu_BaLyEn_6	112	117	PF01217	0.461
TRG_ENDOCYTIC_2	45	48	PF00928	0.436
TRG_ENDOCYTIC_2	52	55	PF00928	0.414
TRG_ER_diArg_1	18	21	PF00400	0.494
TRG_ER_diArg_1	26	28	PF00400	0.655
TRG_ER_diArg_1	29	32	PF00400	0.645
TRG_ER_diArg_1	439	441	PF00400	0.568
TRG_ER_diArg_1	448	451	PF00400	0.515

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAC4	Leptomonas seymouri	50%	67%
A4HUV9	Leishmania infantum	98%	100%