LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Cytoplasmic_translation_machinery_associated_prot ein_putative/GeneDB:LmjF.11.0180

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Cytoplasmic_translation_machinery_associated_prot ein_putative/GeneDB:LmjF.11.0180
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H6H9_LEIDO
TriTrypDb:
LdBPK_110180.1 , LdCL_110006700 , LDHU3_11.0210
Length:
196

Annotations

Annotations by Jardim et al.

Translation, cytoplasmic translation machinery associated Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 12
GO:0110165 cellular anatomical entity 1 12

Expansion

Sequence features

A0A3S5H6H9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6H9

Function

Biological processes
Term Name Level Count
GO:0001731 formation of translation preinitiation complex 7 1
GO:0009987 cellular process 1 1
GO:0016043 cellular component organization 3 1
GO:0022607 cellular component assembly 4 1
GO:0022618 ribonucleoprotein complex assembly 6 1
GO:0043933 protein-containing complex organization 4 1
GO:0065003 protein-containing complex assembly 5 1
GO:0071826 ribonucleoprotein complex subunit organization 5 1
GO:0071840 cellular component organization or biogenesis 2 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 12
GO:0003723 RNA binding 4 12
GO:0005488 binding 1 12
GO:0097159 organic cyclic compound binding 2 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 9 13 PF00082 0.231
DOC_MAPK_gen_1 51 57 PF00069 0.440
DOC_USP7_MATH_1 20 24 PF00917 0.492
DOC_USP7_MATH_1 50 54 PF00917 0.452
DOC_USP7_UBL2_3 165 169 PF12436 0.504
DOC_USP7_UBL2_3 91 95 PF12436 0.440
LIG_APCC_ABBA_1 141 146 PF00400 0.428
LIG_BRCT_BRCA1_1 52 56 PF00533 0.534
LIG_LIR_Apic_2 181 187 PF02991 0.459
LIG_LIR_Gen_1 42 50 PF02991 0.444
LIG_LIR_Nem_3 36 41 PF02991 0.443
LIG_LIR_Nem_3 42 48 PF02991 0.453
LIG_LIR_Nem_3 6 11 PF02991 0.374
LIG_LYPXL_yS_3 38 41 PF13949 0.440
LIG_LYPXL_yS_3 96 99 PF13949 0.468
LIG_PDZ_Class_2 191 196 PF00595 0.589
LIG_SH2_SRC 112 115 PF00017 0.511
LIG_SH2_SRC 144 147 PF00017 0.474
LIG_SH2_SRC 86 89 PF00017 0.423
LIG_SH2_STAT5 112 115 PF00017 0.435
LIG_SH2_STAT5 144 147 PF00017 0.476
LIG_SH2_STAT5 86 89 PF00017 0.423
LIG_SH3_3 82 88 PF00018 0.440
LIG_TRAF2_1 40 43 PF00917 0.416
MOD_CK2_1 157 163 PF00069 0.454
MOD_CK2_1 20 26 PF00069 0.455
MOD_CK2_1 69 75 PF00069 0.472
MOD_GlcNHglycan 114 117 PF01048 0.228
MOD_GlcNHglycan 125 128 PF01048 0.228
MOD_GlcNHglycan 189 192 PF01048 0.442
MOD_GlcNHglycan 3 6 PF01048 0.419
MOD_GSK3_1 153 160 PF00069 0.457
MOD_GSK3_1 65 72 PF00069 0.492
MOD_NEK2_1 1 6 PF00069 0.502
MOD_NEK2_1 189 194 PF00069 0.401
MOD_NEK2_1 69 74 PF00069 0.481
MOD_PIKK_1 69 75 PF00454 0.495
MOD_PKA_1 9 15 PF00069 0.432
MOD_Plk_4 153 159 PF00069 0.457
MOD_Plk_4 3 9 PF00069 0.431
MOD_SUMO_rev_2 21 30 PF00179 0.501
TRG_ENDOCYTIC_2 38 41 PF00928 0.437
TRG_ENDOCYTIC_2 96 99 PF00928 0.468

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4P0 Leptomonas seymouri 84% 100%
A0A0S4JUH4 Bodo saltans 72% 94%
A0A1X0NV76 Trypanosomatidae 71% 100%
A0A3B3IRV3 Homo sapiens 44% 100%
A0A3S5ISC7 Trypanosoma rangeli 73% 100%
A4H9U0 Leishmania braziliensis 92% 100%
A4HUT0 Leishmania infantum 100% 100%
D0A7N4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 69% 97%
E9ANG4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
P87313 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 39% 100%
P89886 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 45% 100%
Q2KIE4 Bos taurus 44% 100%
Q4G009 Rattus norvegicus 44% 100%
Q4QH62 Leishmania major 97% 100%
Q58827 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 35% 100%
Q5PPY1 Xenopus laevis 45% 100%
Q5ZI42 Gallus gallus 44% 100%
Q6DER1 Xenopus tropicalis 45% 100%
Q6NRJ7 Xenopus laevis 45% 100%
Q75AA8 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 42% 100%
Q7ZV34 Danio rerio 44% 100%
Q86KL4 Dictyostelium discoideum 43% 100%
Q9CQ21 Mus musculus 44% 100%
Q9DB27 Mus musculus 44% 100%
Q9ULC4 Homo sapiens 44% 100%
Q9W445 Drosophila melanogaster 45% 100%
V5BWL1 Trypanosoma cruzi 70% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS