GRIP domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

GRIP domain containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H6H7_LEIDO

TriTrypDb:

LdBPK_110070.1 , LdCL_110005600 , LDHU3_11.0080

Length:

1494

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005794	Golgi apparatus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S5H6H7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1023	1027	PF00656	0.680
CLV_C14_Caspase3-7	1069	1073	PF00656	0.660
CLV_C14_Caspase3-7	1115	1119	PF00656	0.595
CLV_C14_Caspase3-7	1175	1179	PF00656	0.511
CLV_C14_Caspase3-7	1384	1388	PF00656	0.496
CLV_C14_Caspase3-7	425	429	PF00656	0.666
CLV_C14_Caspase3-7	471	475	PF00656	0.677
CLV_C14_Caspase3-7	517	521	PF00656	0.680
CLV_C14_Caspase3-7	563	567	PF00656	0.680
CLV_C14_Caspase3-7	609	613	PF00656	0.666
CLV_C14_Caspase3-7	655	659	PF00656	0.666
CLV_C14_Caspase3-7	701	705	PF00656	0.631
CLV_C14_Caspase3-7	747	751	PF00656	0.644
CLV_C14_Caspase3-7	793	797	PF00656	0.630
CLV_C14_Caspase3-7	839	843	PF00656	0.644
CLV_C14_Caspase3-7	885	889	PF00656	0.644
CLV_C14_Caspase3-7	931	935	PF00656	0.679
CLV_C14_Caspase3-7	977	981	PF00656	0.637
CLV_NRD_NRD_1	1328	1330	PF00675	0.529
CLV_PCSK_KEX2_1	1302	1304	PF00082	0.573
CLV_PCSK_KEX2_1	1414	1416	PF00082	0.554
CLV_PCSK_PC1ET2_1	1302	1304	PF00082	0.573
CLV_PCSK_PC1ET2_1	1414	1416	PF00082	0.548
CLV_PCSK_SKI1_1	1160	1164	PF00082	0.525
CLV_PCSK_SKI1_1	3	7	PF00082	0.590
CLV_PCSK_SKI1_1	62	66	PF00082	0.535
CLV_Separin_Metazoa	1272	1276	PF03568	0.505
DEG_APCC_KENBOX_2	1407	1411	PF00400	0.545
DEG_Nend_UBRbox_2	1	3	PF02207	0.505
DOC_MAPK_gen_1	352	360	PF00069	0.531
DOC_MAPK_gen_1	44	51	PF00069	0.573
DOC_MAPK_MEF2A_6	1435	1444	PF00069	0.451
DOC_PP1_RVXF_1	246	253	PF00149	0.373
DOC_USP7_MATH_1	1020	1024	PF00917	0.583
DOC_USP7_MATH_1	1066	1070	PF00917	0.563
DOC_USP7_MATH_1	1112	1116	PF00917	0.538
DOC_USP7_MATH_1	1185	1189	PF00917	0.484
DOC_USP7_MATH_1	1254	1258	PF00917	0.513
DOC_USP7_MATH_1	1365	1369	PF00917	0.484
DOC_USP7_MATH_1	299	303	PF00917	0.616
DOC_USP7_MATH_1	338	342	PF00917	0.550
DOC_USP7_MATH_1	422	426	PF00917	0.568
DOC_USP7_MATH_1	468	472	PF00917	0.580
DOC_USP7_MATH_1	514	518	PF00917	0.584
DOC_USP7_MATH_1	560	564	PF00917	0.584
DOC_USP7_MATH_1	606	610	PF00917	0.586
DOC_USP7_MATH_1	652	656	PF00917	0.584
DOC_USP7_MATH_1	698	702	PF00917	0.548
DOC_USP7_MATH_1	744	748	PF00917	0.547
DOC_USP7_MATH_1	790	794	PF00917	0.547
DOC_USP7_MATH_1	836	840	PF00917	0.565
DOC_USP7_MATH_1	882	886	PF00917	0.547
DOC_USP7_MATH_1	928	932	PF00917	0.582
DOC_USP7_MATH_1	974	978	PF00917	0.582
DOC_USP7_UBL2_3	1156	1160	PF12436	0.483
DOC_USP7_UBL2_3	58	62	PF12436	0.523
DOC_WW_Pin1_4	1203	1208	PF00397	0.481
DOC_WW_Pin1_4	1354	1359	PF00397	0.625
DOC_WW_Pin1_4	284	289	PF00397	0.722
DOC_WW_Pin1_4	316	321	PF00397	0.644
DOC_WW_Pin1_4	91	96	PF00397	0.540
LIG_14-3-3_CanoR_1	1172	1180	PF00244	0.575
LIG_14-3-3_CanoR_1	1186	1194	PF00244	0.460
LIG_14-3-3_CanoR_1	1303	1311	PF00244	0.579
LIG_14-3-3_CanoR_1	310	320	PF00244	0.649
LIG_Actin_WH2_2	1262	1279	PF00022	0.512
LIG_BRCT_BRCA1_1	340	344	PF00533	0.470
LIG_deltaCOP1_diTrp_1	1231	1238	PF00928	0.415
LIG_FHA_1	1247	1253	PF00498	0.483
LIG_FHA_1	1316	1322	PF00498	0.532
LIG_FHA_1	361	367	PF00498	0.519
LIG_FHA_1	46	52	PF00498	0.436
LIG_FHA_1	92	98	PF00498	0.521
LIG_FHA_2	1304	1310	PF00498	0.578
LIG_FHA_2	134	140	PF00498	0.526
LIG_FHA_2	1382	1388	PF00498	0.489
LIG_FHA_2	1469	1475	PF00498	0.410
LIG_FHA_2	26	32	PF00498	0.553
LIG_FHA_2	54	60	PF00498	0.491
LIG_FHA_2	63	69	PF00498	0.448
LIG_GBD_Chelix_1	32	40	PF00786	0.525
LIG_HCF-1_HBM_1	325	328	PF13415	0.637
LIG_LIR_Gen_1	45	51	PF02991	0.436
LIG_LIR_Nem_3	1235	1241	PF02991	0.427
LIG_LIR_Nem_3	45	50	PF02991	0.431
LIG_PCNA_yPIPBox_3	1414	1428	PF02747	0.520
LIG_REV1ctd_RIR_1	2	11	PF16727	0.521
LIG_SH2_CRK	47	51	PF00017	0.509
LIG_SH2_SRC	151	154	PF00017	0.483
LIG_SH2_STAP1	47	51	PF00017	0.509
LIG_SH2_STAT5	1251	1254	PF00017	0.501
LIG_SH2_STAT5	1427	1430	PF00017	0.496
LIG_SH2_STAT5	1446	1449	PF00017	0.375
LIG_SH2_STAT5	1454	1457	PF00017	0.305
LIG_SH2_STAT5	151	154	PF00017	0.546
LIG_SH2_STAT5	47	50	PF00017	0.459
LIG_SH3_1	317	323	PF00018	0.534
LIG_SH3_3	1485	1491	PF00018	0.563
LIG_SH3_3	287	293	PF00018	0.742
LIG_SH3_3	317	323	PF00018	0.600
LIG_SUMO_SIM_anti_2	17	23	PF11976	0.533
LIG_SUMO_SIM_anti_2	272	281	PF11976	0.509
LIG_SUMO_SIM_par_1	47	52	PF11976	0.436
LIG_TRAF2_1	1296	1299	PF00917	0.518
LIG_TRAF2_1	15	18	PF00917	0.530
LIG_TRAF2_1	182	185	PF00917	0.538
LIG_TRAF2_1	237	240	PF00917	0.539
LIG_TRAF2_1	322	325	PF00917	0.644
LIG_UBA3_1	140	148	PF00899	0.410
LIG_WRC_WIRS_1	1382	1387	PF05994	0.509
MOD_CDK_SPxxK_3	91	98	PF00069	0.536
MOD_CK1_1	1151	1157	PF00069	0.412
MOD_CK1_1	1279	1285	PF00069	0.517
MOD_CK1_1	1357	1363	PF00069	0.561
MOD_CK1_1	1388	1394	PF00069	0.513
MOD_CK1_1	241	247	PF00069	0.519
MOD_CK1_1	316	322	PF00069	0.667
MOD_CK1_1	67	73	PF00069	0.522
MOD_CK2_1	1151	1157	PF00069	0.482
MOD_CK2_1	1203	1209	PF00069	0.469
MOD_CK2_1	1210	1216	PF00069	0.448
MOD_CK2_1	128	134	PF00069	0.572
MOD_CK2_1	1293	1299	PF00069	0.539
MOD_CK2_1	1303	1309	PF00069	0.522
MOD_CK2_1	1468	1474	PF00069	0.375
MOD_CK2_1	179	185	PF00069	0.628
MOD_CK2_1	220	226	PF00069	0.547
MOD_CK2_1	234	240	PF00069	0.429
MOD_CK2_1	25	31	PF00069	0.553
MOD_CK2_1	277	283	PF00069	0.660
MOD_CK2_1	318	324	PF00069	0.665
MOD_CK2_1	5	11	PF00069	0.458
MOD_CK2_1	53	59	PF00069	0.485
MOD_CK2_1	86	92	PF00069	0.465
MOD_GlcNHglycan	1160	1163	PF01048	0.454
MOD_GlcNHglycan	1196	1199	PF01048	0.390
MOD_GlcNHglycan	1256	1259	PF01048	0.549
MOD_GlcNHglycan	1283	1286	PF01048	0.586
MOD_GlcNHglycan	1363	1366	PF01048	0.496
MOD_GlcNHglycan	223	226	PF01048	0.547
MOD_GlcNHglycan	301	304	PF01048	0.614
MOD_GlcNHglycan	313	316	PF01048	0.698
MOD_GlcNHglycan	87	91	PF01048	0.465
MOD_GSK3_1	1199	1206	PF00069	0.475
MOD_GSK3_1	128	135	PF00069	0.533
MOD_GSK3_1	1316	1323	PF00069	0.534
MOD_GSK3_1	1357	1364	PF00069	0.553
MOD_GSK3_1	1381	1388	PF00069	0.505
MOD_GSK3_1	1392	1399	PF00069	0.428
MOD_GSK3_1	234	241	PF00069	0.547
MOD_GSK3_1	294	301	PF00069	0.629
MOD_GSK3_1	309	316	PF00069	0.579
MOD_GSK3_1	45	52	PF00069	0.490
MOD_N-GLC_1	1361	1366	PF02516	0.508
MOD_N-GLC_1	1419	1424	PF02516	0.445
MOD_N-GLC_1	204	209	PF02516	0.541
MOD_N-GLC_1	227	232	PF02516	0.567
MOD_N-GLC_1	284	289	PF02516	0.659
MOD_NEK2_1	1148	1153	PF00069	0.420
MOD_NEK2_1	1194	1199	PF00069	0.383
MOD_NEK2_1	1385	1390	PF00069	0.516
MOD_NEK2_1	1396	1401	PF00069	0.433
MOD_NEK2_1	1473	1478	PF00069	0.375
MOD_NEK2_1	277	282	PF00069	0.693
MOD_NEK2_1	49	54	PF00069	0.437
MOD_NEK2_1	5	10	PF00069	0.529
MOD_PIKK_1	1303	1309	PF00454	0.575
MOD_PIKK_1	1341	1347	PF00454	0.606
MOD_PIKK_1	1388	1394	PF00454	0.513
MOD_PIKK_1	151	157	PF00454	0.463
MOD_PIKK_1	294	300	PF00454	0.604
MOD_PIKK_1	74	80	PF00454	0.512
MOD_PKA_1	1302	1308	PF00069	0.573
MOD_PKA_1	6	12	PF00069	0.527
MOD_PKA_2	1171	1177	PF00069	0.516
MOD_PKA_2	1185	1191	PF00069	0.556
MOD_PKA_2	1254	1260	PF00069	0.550
MOD_PKA_2	1302	1308	PF00069	0.591
MOD_PKA_2	1309	1315	PF00069	0.489
MOD_PKA_2	1388	1394	PF00069	0.653
MOD_PKA_2	277	283	PF00069	0.581
MOD_PKA_2	309	315	PF00069	0.617
MOD_Plk_1	1148	1154	PF00069	0.465
MOD_Plk_1	1234	1240	PF00069	0.364
MOD_Plk_1	1279	1285	PF00069	0.517
MOD_Plk_1	133	139	PF00069	0.530
MOD_Plk_1	1361	1367	PF00069	0.515
MOD_Plk_1	1419	1425	PF00069	0.444
MOD_Plk_1	204	210	PF00069	0.531
MOD_Plk_1	227	233	PF00069	0.606
MOD_Plk_1	263	269	PF00069	0.574
MOD_Plk_1	278	284	PF00069	0.483
MOD_Plk_1	67	73	PF00069	0.665
MOD_Plk_2-3	1309	1315	PF00069	0.585
MOD_Plk_2-3	1381	1387	PF00069	0.433
MOD_Plk_2-3	199	205	PF00069	0.563
MOD_Plk_2-3	234	240	PF00069	0.552
MOD_Plk_2-3	362	368	PF00069	0.523
MOD_Plk_4	1148	1154	PF00069	0.413
MOD_Plk_4	1365	1371	PF00069	0.480
MOD_Plk_4	1381	1387	PF00069	0.328
MOD_Plk_4	1419	1425	PF00069	0.444
MOD_Plk_4	1468	1474	PF00069	0.375
MOD_Plk_4	212	218	PF00069	0.596
MOD_Plk_4	227	233	PF00069	0.506
MOD_Plk_4	45	51	PF00069	0.436
MOD_ProDKin_1	1203	1209	PF00069	0.484
MOD_ProDKin_1	1354	1360	PF00069	0.615
MOD_ProDKin_1	284	290	PF00069	0.725
MOD_ProDKin_1	316	322	PF00069	0.639
MOD_ProDKin_1	91	97	PF00069	0.539
MOD_SUMO_for_1	1413	1416	PF00179	0.551
MOD_SUMO_for_1	15	18	PF00179	0.530
MOD_SUMO_rev_2	1296	1304	PF00179	0.576
MOD_SUMO_rev_2	182	191	PF00179	0.549
MOD_SUMO_rev_2	37	45	PF00179	0.502
TRG_DiLeu_BaEn_1	17	22	PF01217	0.535
TRG_DiLeu_BaEn_4	1037	1043	PF01217	0.653
TRG_DiLeu_BaEn_4	1083	1089	PF01217	0.624
TRG_DiLeu_BaEn_4	17	23	PF01217	0.533
TRG_DiLeu_BaEn_4	393	399	PF01217	0.511
TRG_DiLeu_BaEn_4	439	445	PF01217	0.567
TRG_DiLeu_BaEn_4	485	491	PF01217	0.583
TRG_DiLeu_BaEn_4	531	537	PF01217	0.585
TRG_DiLeu_BaEn_4	577	583	PF01217	0.585
TRG_DiLeu_BaEn_4	623	629	PF01217	0.654
TRG_DiLeu_BaEn_4	669	675	PF01217	0.654
TRG_DiLeu_BaEn_4	715	721	PF01217	0.549
TRG_DiLeu_BaEn_4	761	767	PF01217	0.549
TRG_DiLeu_BaEn_4	807	813	PF01217	0.619
TRG_DiLeu_BaEn_4	853	859	PF01217	0.619
TRG_DiLeu_BaEn_4	899	905	PF01217	0.619
TRG_DiLeu_BaEn_4	945	951	PF01217	0.654
TRG_DiLeu_BaEn_4	991	997	PF01217	0.654
TRG_ENDOCYTIC_2	47	50	PF00928	0.511
TRG_ER_diArg_1	1321	1324	PF00400	0.523
TRG_ER_diArg_1	69	72	PF00400	0.520
TRG_NES_CRM1_1	142	153	PF08389	0.476
TRG_NES_CRM1_1	265	279	PF08389	0.572
TRG_Pf-PMV_PEXEL_1	1448	1452	PF00026	0.375
TRG_Pf-PMV_PEXEL_1	236	240	PF00026	0.544
TRG_Pf-PMV_PEXEL_1	62	66	PF00026	0.594

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HCL0	Leishmania braziliensis	28%	100%
A4HCL2	Leishmania braziliensis	30%	72%
A4HUR9	Leishmania infantum	89%	100%
Q4QH73	Leishmania major	87%	100%