RNA-binding_protein_5_putative/GeneDB:LmjF.09.006 0

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein 5, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H6A7_LEIDO

TriTrypDb:

LdBPK_090080.1 , LdCL_090005700 , LDHU3_09.0110

Length:

131

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H6A7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H6A7

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	13
GO:0003723	RNA binding	4	13
GO:0005488	binding	1	13
GO:0097159	organic cyclic compound binding	2	13
GO:1901363	heterocyclic compound binding	2	13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	59	63	PF00656	0.401
CLV_PCSK_SKI1_1	23	27	PF00082	0.272
DOC_MAPK_gen_1	76	84	PF00069	0.492
DOC_MAPK_MEF2A_6	76	84	PF00069	0.507
DOC_USP7_MATH_1	87	91	PF00917	0.490
DOC_WW_Pin1_4	117	122	PF00397	0.588
DOC_WW_Pin1_4	2	7	PF00397	0.486
DOC_WW_Pin1_4	27	32	PF00397	0.470
LIG_14-3-3_CanoR_1	34	42	PF00244	0.478
LIG_BIR_II_1	1	5	PF00653	0.491
LIG_eIF4E_1	123	129	PF01652	0.454
LIG_eIF4E_1	20	26	PF01652	0.512
LIG_FHA_1	6	12	PF00498	0.455
LIG_LIR_Apic_2	2	6	PF02991	0.487
LIG_LIR_Nem_3	27	32	PF02991	0.448
LIG_LYPXL_S_1	94	98	PF13949	0.559
LIG_LYPXL_yS_3	95	98	PF13949	0.558
LIG_SH2_CRK	110	114	PF00017	0.549
LIG_SH2_CRK	52	56	PF00017	0.411
LIG_SH2_SRC	110	113	PF00017	0.597
LIG_SH2_SRC	117	120	PF00017	0.505
LIG_SH2_STAT5	114	117	PF00017	0.481
LIG_SH2_STAT5	12	15	PF00017	0.432
LIG_SH3_3	106	112	PF00018	0.549
LIG_SH3_3	115	121	PF00018	0.589
LIG_SUMO_SIM_par_1	24	30	PF11976	0.512
MOD_CDK_SPxxK_3	2	9	PF00069	0.472
MOD_CDK_SPxxK_3	27	34	PF00069	0.470
MOD_CK1_1	2	8	PF00069	0.481
MOD_CK2_1	12	18	PF00069	0.422
MOD_GlcNHglycan	104	107	PF01048	0.384
MOD_GlcNHglycan	88	92	PF01048	0.496
MOD_GSK3_1	117	124	PF00069	0.586
MOD_GSK3_1	71	78	PF00069	0.487
MOD_PKA_2	75	81	PF00069	0.479
MOD_Plk_2-3	18	24	PF00069	0.509
MOD_ProDKin_1	117	123	PF00069	0.586
MOD_ProDKin_1	2	8	PF00069	0.481
MOD_ProDKin_1	27	33	PF00069	0.470
TRG_ENDOCYTIC_2	110	113	PF00928	0.450
TRG_ENDOCYTIC_2	123	126	PF00928	0.551
TRG_ENDOCYTIC_2	52	55	PF00928	0.411
TRG_ENDOCYTIC_2	95	98	PF00928	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTR1	Leptomonas seymouri	90%	99%
A0A1X0NNG9	Trypanosomatidae	60%	100%
A0A3R7KCI5	Trypanosoma rangeli	59%	100%
A0A3R7M619	Trypanosoma rangeli	30%	79%
A4H5I3	Leishmania braziliensis	89%	100%
A4HTS4	Leishmania infantum	99%	100%
D0A984	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	100%
E9AMK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
P40565	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	89%
Q4QI29	Leishmania major	96%	100%
V5BIJ7	Trypanosoma cruzi	61%	100%
V5BSY3	Trypanosoma cruzi	38%	66%