AAA domain (Dynein-related subfamily)/von Willebrand factor type A domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

AAA domain (dynein-related subfamily)/von Willebrand factor type A domain containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H681_LEIDO

TriTrypDb:

LdCL_080014900 , LDHU3_08.1290

Length:

2457

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S5H681

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	9
GO:0003824	catalytic activity	1	9
GO:0005488	binding	1	9
GO:0005524	ATP binding	5	9
GO:0016462	pyrophosphatase activity	5	9
GO:0016787	hydrolase activity	2	9
GO:0016817	hydrolase activity, acting on acid anhydrides	3	9
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	9
GO:0016887	ATP hydrolysis activity	7	9
GO:0017076	purine nucleotide binding	4	9

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1401	1405	PF00656	0.441
CLV_C14_Caspase3-7	1471	1475	PF00656	0.342
CLV_C14_Caspase3-7	1535	1539	PF00656	0.532
CLV_C14_Caspase3-7	1628	1632	PF00656	0.614
CLV_C14_Caspase3-7	2075	2079	PF00656	0.585
CLV_C14_Caspase3-7	232	236	PF00656	0.447
CLV_C14_Caspase3-7	2373	2377	PF00656	0.325
CLV_C14_Caspase3-7	407	411	PF00656	0.631
CLV_C14_Caspase3-7	68	72	PF00656	0.520
CLV_C14_Caspase3-7	755	759	PF00656	0.527

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBS0	Leptomonas seymouri	65%	94%
A0A1X0NPT5	Trypanosomatidae	43%	100%
A0A3S5IRB8	Trypanosoma rangeli	45%	100%
A4H5E3	Leishmania braziliensis	84%	100%
E9AMH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QI69	Leishmania major	94%	100%
V5DHX4	Trypanosoma cruzi	44%	100%

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