LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S5H680_LEIDO
TriTrypDb:
LdBPK_080920.1 , LdCL_080014700 , LDHU3_08.1270
Length:
771

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H680
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H680

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 285 289 PF00656 0.727
CLV_C14_Caspase3-7 409 413 PF00656 0.707
CLV_C14_Caspase3-7 722 726 PF00656 0.764
CLV_NRD_NRD_1 374 376 PF00675 0.784
CLV_NRD_NRD_1 481 483 PF00675 0.758
CLV_NRD_NRD_1 728 730 PF00675 0.770
CLV_NRD_NRD_1 73 75 PF00675 0.804
CLV_PCSK_FUR_1 374 378 PF00082 0.781
CLV_PCSK_KEX2_1 374 376 PF00082 0.784
CLV_PCSK_KEX2_1 385 387 PF00082 0.647
CLV_PCSK_KEX2_1 481 483 PF00082 0.758
CLV_PCSK_KEX2_1 728 730 PF00082 0.770
CLV_PCSK_KEX2_1 73 75 PF00082 0.808
CLV_PCSK_PC1ET2_1 376 378 PF00082 0.779
CLV_PCSK_PC1ET2_1 385 387 PF00082 0.672
CLV_PCSK_SKI1_1 154 158 PF00082 0.774
CLV_PCSK_SKI1_1 425 429 PF00082 0.752
CLV_PCSK_SKI1_1 653 657 PF00082 0.757
DEG_APCC_DBOX_1 11 19 PF00400 0.741
DEG_APCC_DBOX_1 632 640 PF00400 0.744
DEG_APCC_DBOX_1 696 704 PF00400 0.775
DEG_COP1_1 565 575 PF00400 0.782
DEG_Nend_UBRbox_2 1 3 PF02207 0.745
DEG_SCF_FBW7_1 298 305 PF00400 0.729
DEG_SCF_FBW7_1 453 459 PF00400 0.615
DEG_SCF_FBW7_1 610 616 PF00400 0.749
DEG_SCF_FBW7_2 572 578 PF00400 0.748
DEG_SPOP_SBC_1 155 159 PF00917 0.757
DEG_SPOP_SBC_1 302 306 PF00917 0.718
DOC_CKS1_1 146 151 PF01111 0.755
DOC_CKS1_1 453 458 PF01111 0.619
DOC_CKS1_1 572 577 PF01111 0.751
DOC_CKS1_1 610 615 PF01111 0.713
DOC_CKS1_1 766 771 PF01111 0.786
DOC_CYCLIN_yClb3_PxF_3 497 503 PF00134 0.609
DOC_CYCLIN_yCln2_LP_2 53 59 PF00134 0.803
DOC_MAPK_gen_1 393 402 PF00069 0.737
DOC_PP2B_LxvP_1 495 498 PF13499 0.719
DOC_PP4_FxxP_1 631 634 PF00568 0.751
DOC_USP7_MATH_1 109 113 PF00917 0.689
DOC_USP7_MATH_1 255 259 PF00917 0.628
DOC_USP7_MATH_1 268 272 PF00917 0.545
DOC_USP7_MATH_1 302 306 PF00917 0.736
DOC_USP7_MATH_1 363 367 PF00917 0.762
DOC_USP7_MATH_1 441 445 PF00917 0.700
DOC_USP7_MATH_1 489 493 PF00917 0.769
DOC_USP7_MATH_1 543 547 PF00917 0.743
DOC_USP7_MATH_1 68 72 PF00917 0.750
DOC_USP7_MATH_1 78 82 PF00917 0.557
DOC_WW_Pin1_4 122 127 PF00397 0.737
DOC_WW_Pin1_4 131 136 PF00397 0.629
DOC_WW_Pin1_4 145 150 PF00397 0.580
DOC_WW_Pin1_4 16 21 PF00397 0.744
DOC_WW_Pin1_4 207 212 PF00397 0.759
DOC_WW_Pin1_4 298 303 PF00397 0.773
DOC_WW_Pin1_4 305 310 PF00397 0.673
DOC_WW_Pin1_4 316 321 PF00397 0.534
DOC_WW_Pin1_4 357 362 PF00397 0.736
DOC_WW_Pin1_4 364 369 PF00397 0.671
DOC_WW_Pin1_4 379 384 PF00397 0.583
DOC_WW_Pin1_4 412 417 PF00397 0.766
DOC_WW_Pin1_4 425 430 PF00397 0.592
DOC_WW_Pin1_4 452 457 PF00397 0.698
DOC_WW_Pin1_4 465 470 PF00397 0.668
DOC_WW_Pin1_4 493 498 PF00397 0.762
DOC_WW_Pin1_4 562 567 PF00397 0.667
DOC_WW_Pin1_4 571 576 PF00397 0.684
DOC_WW_Pin1_4 609 614 PF00397 0.765
DOC_WW_Pin1_4 64 69 PF00397 0.748
DOC_WW_Pin1_4 656 661 PF00397 0.751
DOC_WW_Pin1_4 695 700 PF00397 0.749
DOC_WW_Pin1_4 704 709 PF00397 0.656
DOC_WW_Pin1_4 74 79 PF00397 0.566
DOC_WW_Pin1_4 765 770 PF00397 0.780
LIG_14-3-3_CanoR_1 189 197 PF00244 0.747
LIG_14-3-3_CanoR_1 364 368 PF00244 0.729
LIG_14-3-3_CanoR_1 388 396 PF00244 0.706
LIG_14-3-3_CanoR_1 450 456 PF00244 0.769
LIG_14-3-3_CanoR_1 481 486 PF00244 0.764
LIG_14-3-3_CanoR_1 542 552 PF00244 0.737
LIG_14-3-3_CanoR_1 653 662 PF00244 0.754
LIG_14-3-3_CanoR_1 668 672 PF00244 0.585
LIG_14-3-3_CanoR_1 728 733 PF00244 0.771
LIG_14-3-3_CanoR_1 738 748 PF00244 0.641
LIG_Actin_WH2_2 640 655 PF00022 0.603
LIG_BIR_III_2 193 197 PF00653 0.749
LIG_BRCT_BRCA1_1 46 50 PF00533 0.722
LIG_eIF4E_1 396 402 PF01652 0.737
LIG_FHA_1 162 168 PF00498 0.765
LIG_FHA_1 204 210 PF00498 0.759
LIG_FHA_1 305 311 PF00498 0.760
LIG_FHA_1 348 354 PF00498 0.604
LIG_FHA_1 440 446 PF00498 0.742
LIG_FHA_1 516 522 PF00498 0.755
LIG_FHA_1 618 624 PF00498 0.730
LIG_FHA_1 646 652 PF00498 0.746
LIG_FHA_2 157 163 PF00498 0.803
LIG_FHA_2 283 289 PF00498 0.766
LIG_FHA_2 37 43 PF00498 0.738
LIG_FHA_2 407 413 PF00498 0.706
LIG_FHA_2 453 459 PF00498 0.759
LIG_FHA_2 739 745 PF00498 0.768
LIG_IRF3_LxIS_1 60 67 PF10401 0.743
LIG_LIR_Apic_2 52 58 PF02991 0.718
LIG_LIR_Apic_2 628 634 PF02991 0.744
LIG_LIR_Nem_3 47 53 PF02991 0.724
LIG_MYND_1 13 17 PF01753 0.726
LIG_NRP_CendR_1 770 771 PF00754 0.592
LIG_RPA_C_Fungi 214 226 PF08784 0.749
LIG_SH2_STAT3 396 399 PF00017 0.736
LIG_SH3_2 17 22 PF14604 0.714
LIG_SH3_3 10 16 PF00018 0.742
LIG_SH3_3 149 155 PF00018 0.761
LIG_SH3_3 206 212 PF00018 0.758
LIG_SH3_3 377 383 PF00018 0.771
LIG_SH3_3 482 488 PF00018 0.765
LIG_SH3_3 495 501 PF00018 0.603
LIG_SH3_3 557 563 PF00018 0.779
LIG_SH3_3 567 573 PF00018 0.656
LIG_SH3_3 57 63 PF00018 0.690
LIG_SH3_3 669 675 PF00018 0.764
LIG_SH3_3 763 769 PF00018 0.776
LIG_SUMO_SIM_par_1 213 218 PF11976 0.754
LIG_SUMO_SIM_par_1 399 405 PF11976 0.744
LIG_SUMO_SIM_par_1 635 640 PF11976 0.743
LIG_SUMO_SIM_par_1 762 768 PF11976 0.770
LIG_TRAF2_1 527 530 PF00917 0.561
LIG_WRC_WIRS_1 521 526 PF05994 0.698
LIG_WW_2 13 16 PF00397 0.729
MOD_CDC14_SPxK_1 19 22 PF00782 0.762
MOD_CDC14_SPxK_1 382 385 PF00782 0.739
MOD_CDK_SPK_2 122 127 PF00069 0.737
MOD_CDK_SPK_2 131 136 PF00069 0.629
MOD_CDK_SPK_2 364 369 PF00069 0.733
MOD_CDK_SPK_2 656 661 PF00069 0.751
MOD_CDK_SPK_2 765 770 PF00069 0.574
MOD_CDK_SPxK_1 16 22 PF00069 0.748
MOD_CDK_SPxK_1 379 385 PF00069 0.739
MOD_CDK_SPxK_1 765 771 PF00069 0.578
MOD_CDK_SPxxK_3 357 364 PF00069 0.758
MOD_CDK_SPxxK_3 379 386 PF00069 0.774
MOD_CDK_SPxxK_3 562 569 PF00069 0.629
MOD_CK1_1 125 131 PF00069 0.744
MOD_CK1_1 203 209 PF00069 0.762
MOD_CK1_1 272 278 PF00069 0.619
MOD_CK1_1 305 311 PF00069 0.738
MOD_CK1_1 35 41 PF00069 0.748
MOD_CK1_1 357 363 PF00069 0.610
MOD_CK1_1 415 421 PF00069 0.634
MOD_CK1_1 454 460 PF00069 0.752
MOD_CK1_1 496 502 PF00069 0.752
MOD_CK1_1 541 547 PF00069 0.784
MOD_CK1_1 565 571 PF00069 0.777
MOD_CK1_1 621 627 PF00069 0.756
MOD_CK1_1 646 652 PF00069 0.746
MOD_CK1_1 714 720 PF00069 0.773
MOD_CK1_1 727 733 PF00069 0.608
MOD_CK1_1 742 748 PF00069 0.574
MOD_CK1_1 756 762 PF00069 0.587
MOD_CK1_1 765 771 PF00069 0.672
MOD_CK1_1 88 94 PF00069 0.740
MOD_CK2_1 156 162 PF00069 0.804
MOD_CK2_1 170 176 PF00069 0.567
MOD_CK2_1 36 42 PF00069 0.747
MOD_CK2_1 415 421 PF00069 0.634
MOD_CK2_1 524 530 PF00069 0.757
MOD_DYRK1A_RPxSP_1 364 368 PF00069 0.729
MOD_DYRK1A_RPxSP_1 425 429 PF00069 0.752
MOD_GlcNHglycan 111 114 PF01048 0.511
MOD_GlcNHglycan 127 130 PF01048 0.750
MOD_GlcNHglycan 138 141 PF01048 0.618
MOD_GlcNHglycan 253 256 PF01048 0.772
MOD_GlcNHglycan 257 260 PF01048 0.723
MOD_GlcNHglycan 285 288 PF01048 0.770
MOD_GlcNHglycan 342 345 PF01048 0.745
MOD_GlcNHglycan 356 359 PF01048 0.569
MOD_GlcNHglycan 390 393 PF01048 0.707
MOD_GlcNHglycan 408 412 PF01048 0.524
MOD_GlcNHglycan 425 428 PF01048 0.548
MOD_GlcNHglycan 472 475 PF01048 0.752
MOD_GlcNHglycan 491 494 PF01048 0.538
MOD_GlcNHglycan 648 651 PF01048 0.729
MOD_GlcNHglycan 662 665 PF01048 0.564
MOD_GlcNHglycan 68 71 PF01048 0.748
MOD_GlcNHglycan 686 689 PF01048 0.749
MOD_GlcNHglycan 749 752 PF01048 0.758
MOD_GlcNHglycan 87 90 PF01048 0.743
MOD_GlcNHglycan 95 98 PF01048 0.643
MOD_GSK3_1 105 112 PF00069 0.622
MOD_GSK3_1 136 143 PF00069 0.622
MOD_GSK3_1 156 163 PF00069 0.634
MOD_GSK3_1 166 173 PF00069 0.609
MOD_GSK3_1 185 192 PF00069 0.545
MOD_GSK3_1 200 207 PF00069 0.543
MOD_GSK3_1 215 222 PF00069 0.579
MOD_GSK3_1 251 258 PF00069 0.683
MOD_GSK3_1 268 275 PF00069 0.630
MOD_GSK3_1 294 301 PF00069 0.785
MOD_GSK3_1 32 39 PF00069 0.751
MOD_GSK3_1 364 371 PF00069 0.772
MOD_GSK3_1 40 47 PF00069 0.635
MOD_GSK3_1 407 414 PF00069 0.750
MOD_GSK3_1 436 443 PF00069 0.711
MOD_GSK3_1 452 459 PF00069 0.590
MOD_GSK3_1 465 472 PF00069 0.574
MOD_GSK3_1 477 484 PF00069 0.600
MOD_GSK3_1 489 496 PF00069 0.685
MOD_GSK3_1 520 527 PF00069 0.747
MOD_GSK3_1 609 616 PF00069 0.756
MOD_GSK3_1 617 624 PF00069 0.673
MOD_GSK3_1 625 632 PF00069 0.549
MOD_GSK3_1 64 71 PF00069 0.799
MOD_GSK3_1 642 649 PF00069 0.567
MOD_GSK3_1 651 658 PF00069 0.645
MOD_GSK3_1 684 691 PF00069 0.745
MOD_GSK3_1 698 705 PF00069 0.606
MOD_GSK3_1 719 726 PF00069 0.753
MOD_GSK3_1 727 734 PF00069 0.670
MOD_GSK3_1 738 745 PF00069 0.535
MOD_GSK3_1 74 81 PF00069 0.597
MOD_GSK3_1 753 760 PF00069 0.579
MOD_LATS_1 199 205 PF00433 0.767
MOD_N-GLC_1 255 260 PF02516 0.670
MOD_N-GLC_1 283 288 PF02516 0.727
MOD_N-GLC_2 336 338 PF02516 0.721
MOD_NEK2_1 185 190 PF00069 0.737
MOD_NEK2_1 622 627 PF00069 0.762
MOD_NEK2_1 637 642 PF00069 0.560
MOD_NEK2_1 724 729 PF00069 0.763
MOD_NEK2_1 737 742 PF00069 0.615
MOD_NEK2_1 87 92 PF00069 0.793
MOD_NEK2_2 68 73 PF00069 0.752
MOD_PIKK_1 201 207 PF00454 0.779
MOD_PIKK_1 44 50 PF00454 0.721
MOD_PIKK_1 653 659 PF00454 0.755
MOD_PIKK_1 716 722 PF00454 0.734
MOD_PIKK_1 757 763 PF00454 0.761
MOD_PK_1 481 487 PF00069 0.764
MOD_PKA_1 481 487 PF00069 0.764
MOD_PKA_1 728 734 PF00069 0.771
MOD_PKA_2 185 191 PF00069 0.705
MOD_PKA_2 231 237 PF00069 0.726
MOD_PKA_2 268 274 PF00069 0.608
MOD_PKA_2 338 344 PF00069 0.651
MOD_PKA_2 363 369 PF00069 0.763
MOD_PKA_2 449 455 PF00069 0.771
MOD_PKA_2 481 487 PF00069 0.764
MOD_PKA_2 515 521 PF00069 0.771
MOD_PKA_2 541 547 PF00069 0.743
MOD_PKA_2 660 666 PF00069 0.757
MOD_PKA_2 667 673 PF00069 0.681
MOD_PKA_2 727 733 PF00069 0.768
MOD_PKA_2 737 743 PF00069 0.649
MOD_PKB_1 386 394 PF00069 0.717
MOD_Plk_2-3 36 42 PF00069 0.747
MOD_Plk_2-3 588 594 PF00069 0.782
MOD_Plk_4 441 447 PF00069 0.739
MOD_Plk_4 618 624 PF00069 0.772
MOD_ProDKin_1 122 128 PF00069 0.738
MOD_ProDKin_1 131 137 PF00069 0.629
MOD_ProDKin_1 145 151 PF00069 0.581
MOD_ProDKin_1 16 22 PF00069 0.748
MOD_ProDKin_1 207 213 PF00069 0.759
MOD_ProDKin_1 298 304 PF00069 0.771
MOD_ProDKin_1 305 311 PF00069 0.674
MOD_ProDKin_1 316 322 PF00069 0.535
MOD_ProDKin_1 357 363 PF00069 0.738
MOD_ProDKin_1 364 370 PF00069 0.671
MOD_ProDKin_1 379 385 PF00069 0.618
MOD_ProDKin_1 412 418 PF00069 0.766
MOD_ProDKin_1 425 431 PF00069 0.590
MOD_ProDKin_1 452 458 PF00069 0.695
MOD_ProDKin_1 465 471 PF00069 0.667
MOD_ProDKin_1 493 499 PF00069 0.764
MOD_ProDKin_1 562 568 PF00069 0.670
MOD_ProDKin_1 571 577 PF00069 0.682
MOD_ProDKin_1 609 615 PF00069 0.756
MOD_ProDKin_1 64 70 PF00069 0.749
MOD_ProDKin_1 656 662 PF00069 0.752
MOD_ProDKin_1 695 701 PF00069 0.753
MOD_ProDKin_1 704 710 PF00069 0.655
MOD_ProDKin_1 74 80 PF00069 0.565
MOD_ProDKin_1 765 771 PF00069 0.783
MOD_SUMO_rev_2 454 462 PF00179 0.757
TRG_DiLeu_BaLyEn_6 632 637 PF01217 0.743
TRG_ER_diArg_1 250 253 PF00400 0.725
TRG_ER_diArg_1 374 377 PF00400 0.783
TRG_ER_diArg_1 386 389 PF00400 0.628
TRG_ER_diArg_1 481 483 PF00400 0.758
TRG_ER_diArg_1 72 74 PF00400 0.776
TRG_ER_diArg_1 769 771 PF00400 0.585
TRG_NLS_Bipartite_1 374 389 PF00514 0.776
TRG_NLS_MonoExtN_4 383 389 PF00514 0.773
TRG_Pf-PMV_PEXEL_1 261 265 PF00026 0.774

Homologs

Protein Taxonomy Sequence identity Coverage
A4HTN8 Leishmania infantum 100% 100%
E9AMH2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4QI71 Leishmania major 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS