LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H677_LEIDO
TriTrypDb:
LdBPK_080890.1 , LdCL_080014300 , LDHU3_08.1240
Length:
146

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H677
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H677

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 124 126 PF00675 0.483
CLV_NRD_NRD_1 24 26 PF00675 0.532
CLV_NRD_NRD_1 32 34 PF00675 0.485
CLV_PCSK_KEX2_1 124 126 PF00082 0.490
CLV_PCSK_SKI1_1 114 118 PF00082 0.507
CLV_PCSK_SKI1_1 125 129 PF00082 0.525
CLV_PCSK_SKI1_1 33 37 PF00082 0.535
DEG_Nend_Nbox_1 1 3 PF02207 0.491
DOC_CYCLIN_RxL_1 111 121 PF00134 0.473
LIG_14-3-3_CanoR_1 25 30 PF00244 0.582
LIG_14-3-3_CanoR_1 42 50 PF00244 0.567
LIG_14-3-3_CanoR_1 71 75 PF00244 0.489
LIG_BRCT_BRCA1_1 2 6 PF00533 0.475
LIG_CaM_IQ_9 116 131 PF13499 0.453
LIG_FHA_1 121 127 PF00498 0.532
LIG_FHA_1 3 9 PF00498 0.586
LIG_FHA_2 100 106 PF00498 0.598
LIG_SH2_NCK_1 83 87 PF00017 0.589
LIG_SH2_STAP1 83 87 PF00017 0.622
LIG_SH2_STAT3 87 90 PF00017 0.471
LIG_WRC_WIRS_1 1 6 PF05994 0.475
MOD_GlcNHglycan 10 13 PF01048 0.432
MOD_GSK3_1 21 28 PF00069 0.537
MOD_GSK3_1 36 43 PF00069 0.534
MOD_LATS_1 23 29 PF00433 0.573
MOD_NEK2_1 119 124 PF00069 0.497
MOD_NEK2_1 2 7 PF00069 0.540
MOD_NEK2_1 29 34 PF00069 0.519
MOD_NEK2_1 36 41 PF00069 0.452
MOD_NEK2_1 8 13 PF00069 0.525
MOD_PIKK_1 129 135 PF00454 0.547
MOD_PIKK_1 40 46 PF00454 0.506
MOD_PKA_1 25 31 PF00069 0.580
MOD_PKA_2 100 106 PF00069 0.579
MOD_PKA_2 29 35 PF00069 0.518
MOD_PKA_2 70 76 PF00069 0.486
MOD_PKB_1 40 48 PF00069 0.522
TRG_ER_diArg_1 124 126 PF00400 0.541
TRG_NLS_MonoExtN_4 125 132 PF00514 0.478
TRG_Pf-PMV_PEXEL_1 114 118 PF00026 0.514

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3W2 Leptomonas seymouri 68% 100%
A0A1X0NPN9 Trypanosomatidae 37% 95%
A4H5E0 Leishmania braziliensis 78% 100%
A4HTN5 Leishmania infantum 100% 100%
E9AMG9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4QI74 Leishmania major 89% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS