Serine/threonine_kinase_putative/GeneDB:LmjF.07.0 900

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine kinase, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H606_LEIDO

TriTrypDb:

LdBPK_071030.1 , LdCL_070015200 , LDHU3_07.1250

Length:

296

Annotations

LeishMANIAdb annotations

A large and apprently artificial collection of diverse kinetoplastid protein kinases. None of them appear to be TM.

Annotations by Jardim et al.

Protein kinase, serine/threonine kinase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 25
NetGPI	no	yes: 0, no: 25

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1

Expansion

Sequence features

A0A3S5H606

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H606

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	26
GO:0006793	phosphorus metabolic process	3	26
GO:0006796	phosphate-containing compound metabolic process	4	26
GO:0006807	nitrogen compound metabolic process	2	26
GO:0008152	metabolic process	1	26
GO:0009987	cellular process	1	26
GO:0016310	phosphorylation	5	26
GO:0019538	protein metabolic process	3	26
GO:0036211	protein modification process	4	26
GO:0043170	macromolecule metabolic process	3	26
GO:0043412	macromolecule modification	4	26
GO:0044237	cellular metabolic process	2	26
GO:0044238	primary metabolic process	2	26
GO:0071704	organic substance metabolic process	2	26
GO:1901564	organonitrogen compound metabolic process	3	26
GO:0007165	signal transduction	2	2
GO:0035556	intracellular signal transduction	3	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0065007	biological regulation	1	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	26
GO:0003824	catalytic activity	1	26
GO:0004672	protein kinase activity	3	26
GO:0004674	protein serine/threonine kinase activity	4	26
GO:0005488	binding	1	26
GO:0005524	ATP binding	5	26
GO:0016301	kinase activity	4	26
GO:0016740	transferase activity	2	26
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	26
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	26
GO:0017076	purine nucleotide binding	4	26
GO:0030554	adenyl nucleotide binding	5	26
GO:0032553	ribonucleotide binding	3	26
GO:0032555	purine ribonucleotide binding	4	26
GO:0032559	adenyl ribonucleotide binding	5	26
GO:0035639	purine ribonucleoside triphosphate binding	4	26
GO:0036094	small molecule binding	2	26
GO:0043167	ion binding	2	26
GO:0043168	anion binding	3	26
GO:0097159	organic cyclic compound binding	2	26
GO:0097367	carbohydrate derivative binding	2	26
GO:0140096	catalytic activity, acting on a protein	2	26
GO:1901265	nucleoside phosphate binding	3	26
GO:1901363	heterocyclic compound binding	2	26

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	103	105	PF00082	0.376
CLV_PCSK_KEX2_1	5	7	PF00082	0.507
CLV_PCSK_KEX2_1	56	58	PF00082	0.376
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.356
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.507
CLV_PCSK_PC1ET2_1	56	58	PF00082	0.401
CLV_PCSK_SKI1_1	132	136	PF00082	0.356
CLV_PCSK_SKI1_1	245	249	PF00082	0.394
DEG_APCC_DBOX_1	253	261	PF00400	0.391
DOC_MAPK_gen_1	132	141	PF00069	0.356
DOC_MAPK_gen_1	63	73	PF00069	0.379
DOC_MAPK_JIP1_4	135	141	PF00069	0.368
DOC_PP4_FxxP_1	105	108	PF00568	0.400
DOC_USP7_MATH_2	251	257	PF00917	0.504
DOC_USP7_UBL2_3	39	43	PF12436	0.372
DOC_USP7_UBL2_3	5	9	PF12436	0.515
DOC_WW_Pin1_4	171	176	PF00397	0.379
DOC_WW_Pin1_4	280	285	PF00397	0.766
LIG_14-3-3_CanoR_1	159	163	PF00244	0.361
LIG_14-3-3_CanoR_1	233	242	PF00244	0.397
LIG_14-3-3_CanoR_1	245	250	PF00244	0.357
LIG_14-3-3_CanoR_1	254	258	PF00244	0.351
LIG_deltaCOP1_diTrp_1	194	203	PF00928	0.362
LIG_EH1_1	83	91	PF00400	0.410
LIG_eIF4E_1	84	90	PF01652	0.410
LIG_FHA_1	144	150	PF00498	0.383
LIG_FHA_1	284	290	PF00498	0.741
LIG_FHA_2	220	226	PF00498	0.402
LIG_FHA_2	274	280	PF00498	0.668
LIG_FHA_2	30	36	PF00498	0.406
LIG_FHA_2	89	95	PF00498	0.437
LIG_LIR_Apic_2	174	180	PF02991	0.356
LIG_LIR_Gen_1	18	27	PF02991	0.370
LIG_LIR_Gen_1	94	102	PF02991	0.360
LIG_LIR_Nem_3	18	24	PF02991	0.363
LIG_LIR_Nem_3	185	191	PF02991	0.383
LIG_LIR_Nem_3	94	99	PF02991	0.342
LIG_Pex14_2	266	270	PF04695	0.440
LIG_RPA_C_Fungi	228	240	PF08784	0.504
LIG_SH2_CRK	188	192	PF00017	0.368
LIG_SH2_PTP2	177	180	PF00017	0.356
LIG_SH2_STAT3	113	116	PF00017	0.356
LIG_SH2_STAT5	113	116	PF00017	0.356
LIG_SH2_STAT5	123	126	PF00017	0.356
LIG_SH2_STAT5	177	180	PF00017	0.362
LIG_SH2_STAT5	209	212	PF00017	0.364
LIG_SH2_STAT5	84	87	PF00017	0.356
LIG_SUMO_SIM_anti_2	58	63	PF11976	0.362
LIG_SUMO_SIM_par_1	244	250	PF11976	0.382
LIG_SUMO_SIM_par_1	69	75	PF11976	0.344
LIG_SUMO_SIM_par_1	85	91	PF11976	0.411
LIG_UBA3_1	95	103	PF00899	0.356
MOD_CK1_1	163	169	PF00069	0.328
MOD_CK1_1	280	286	PF00069	0.769
MOD_CK2_1	219	225	PF00069	0.394
MOD_CK2_1	273	279	PF00069	0.658
MOD_CK2_1	29	35	PF00069	0.390
MOD_CK2_1	88	94	PF00069	0.410
MOD_GlcNHglycan	100	103	PF01048	0.435
MOD_GlcNHglycan	162	165	PF01048	0.492
MOD_GlcNHglycan	235	238	PF01048	0.464
MOD_GSK3_1	143	150	PF00069	0.375
MOD_GSK3_1	15	22	PF00069	0.388
MOD_GSK3_1	163	170	PF00069	0.386
MOD_GSK3_1	241	248	PF00069	0.397
MOD_GSK3_1	273	280	PF00069	0.645
MOD_GSK3_1	283	290	PF00069	0.742
MOD_N-GLC_1	143	148	PF02516	0.391
MOD_N-GLC_1	19	24	PF02516	0.387
MOD_N-GLC_2	122	124	PF02516	0.434
MOD_NEK2_1	12	17	PF00069	0.413
MOD_NEK2_1	152	157	PF00069	0.380
MOD_NEK2_1	167	172	PF00069	0.309
MOD_NEK2_1	77	82	PF00069	0.442
MOD_NEK2_2	143	148	PF00069	0.410
MOD_PKA_2	158	164	PF00069	0.485
MOD_PKA_2	253	259	PF00069	0.375
MOD_PKA_2	27	33	PF00069	0.491
MOD_Plk_1	143	149	PF00069	0.391
MOD_Plk_2-3	253	259	PF00069	0.504
MOD_Plk_4	163	169	PF00069	0.394
MOD_ProDKin_1	171	177	PF00069	0.379
MOD_ProDKin_1	280	286	PF00069	0.762
MOD_SUMO_for_1	134	137	PF00179	0.356
MOD_SUMO_for_1	55	58	PF00179	0.377
TRG_ENDOCYTIC_2	188	191	PF00928	0.367
TRG_ENDOCYTIC_2	209	212	PF00928	0.364
TRG_ENDOCYTIC_2	84	87	PF00928	0.359
TRG_NES_CRM1_1	53	67	PF08389	0.373
TRG_Pf-PMV_PEXEL_1	132	137	PF00026	0.356
TRG_Pf-PMV_PEXEL_1	245	250	PF00026	0.423

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P215	Leptomonas seymouri	31%	100%
A0A0N0P3N5	Leptomonas seymouri	33%	69%
A0A0N0P4J7	Leptomonas seymouri	27%	67%
A0A0N0P787	Leptomonas seymouri	33%	77%
A0A0N0P8H5	Leptomonas seymouri	34%	89%
A0A0N1HWQ2	Leptomonas seymouri	33%	98%
A0A0N1I6T8	Leptomonas seymouri	95%	100%
A0A0N1IIF9	Leptomonas seymouri	67%	100%
A0A0N1IM47	Leptomonas seymouri	32%	81%
A0A0N1IMI0	Leptomonas seymouri	26%	100%
A0A0N1PC31	Leptomonas seymouri	33%	76%
A0A0N1PC32	Leptomonas seymouri	33%	76%
A0A0N1PD05	Leptomonas seymouri	30%	66%
A0A0N1PDW7	Leptomonas seymouri	39%	75%
A0A0S4IMB7	Bodo saltans	31%	67%
A0A0S4IRU8	Bodo saltans	32%	69%
A0A0S4IX86	Bodo saltans	32%	69%
A0A0S4IZY3	Bodo saltans	35%	88%
A0A0S4J3Y5	Bodo saltans	31%	69%
A0A0S4J4B3	Bodo saltans	72%	66%
A0A0S4J4X4	Bodo saltans	32%	98%
A0A0S4J6L4	Bodo saltans	33%	78%
A0A0S4JA09	Bodo saltans	32%	72%
A0A0S4JBR3	Bodo saltans	33%	94%
A0A0S4JCG2	Bodo saltans	63%	66%
A0A0S4JF22	Bodo saltans	29%	83%
A0A0S4JK24	Bodo saltans	32%	68%
A0A0S4JPZ7	Bodo saltans	30%	71%
A0A0S4JUJ2	Bodo saltans	35%	100%
A0A0S4JWD5	Bodo saltans	34%	76%
A0A0S4KFT7	Bodo saltans	33%	88%
A0A0S4KMV7	Bodo saltans	41%	92%
A0A0S4KN74	Bodo saltans	32%	91%
A0A1X0NIA0	Trypanosomatidae	31%	69%
A0A1X0NIX2	Trypanosomatidae	29%	67%
A0A1X0NKA1	Trypanosomatidae	31%	67%
A0A1X0NQ63	Trypanosomatidae	76%	100%
A0A1X0NRZ9	Trypanosomatidae	28%	80%
A0A1X0NTR6	Trypanosomatidae	38%	84%
A0A1X0NUQ4	Trypanosomatidae	35%	78%
A0A1X0NY93	Trypanosomatidae	32%	76%
A0A1X0NYK8	Trypanosomatidae	32%	96%
A0A1X0NYQ8	Trypanosomatidae	28%	94%
A0A1X0P527	Trypanosomatidae	29%	67%
A0A1X0P5B1	Trypanosomatidae	37%	90%
A0A1X0P5F2	Trypanosomatidae	37%	90%
A0A1X0P692	Trypanosomatidae	31%	82%
A0A1X0P6V1	Trypanosomatidae	64%	100%
A0A1X0P735	Trypanosomatidae	65%	100%
A0A1X0P7V0	Trypanosomatidae	35%	88%
A0A1X0P8A0	Trypanosomatidae	29%	95%
A0A1X0P8F7	Trypanosomatidae	29%	68%
A0A3Q8IAQ1	Leishmania donovani	34%	100%
A0A3Q8IB30	Leishmania donovani	33%	100%
A0A3Q8IB74	Leishmania donovani	24%	100%
A0A3Q8IBT5	Leishmania donovani	26%	100%
A0A3Q8IC87	Leishmania donovani	38%	100%
A0A3Q8IEH3	Leishmania donovani	33%	100%
A0A3Q8IFK8	Leishmania donovani	30%	67%
A0A3Q8IFW0	Leishmania donovani	32%	69%
A0A3Q8IH39	Leishmania donovani	28%	100%
A0A3Q8INQ4	Leishmania donovani	33%	100%
A0A3Q8INS5	Leishmania donovani	25%	99%
A0A3Q8IPR6	Leishmania donovani	26%	100%
A0A3Q8ITZ9	Leishmania donovani	23%	100%
A0A3R7K5P9	Trypanosoma rangeli	38%	79%
A0A3R7KCZ4	Trypanosoma rangeli	29%	73%
A0A3R7M5C7	Trypanosoma rangeli	78%	100%
A0A3R7MHW5	Trypanosoma rangeli	35%	74%
A0A3R7MJP3	Trypanosoma rangeli	29%	100%
A0A3R7MKG5	Trypanosoma rangeli	28%	67%
A0A3R7N4D8	Trypanosoma rangeli	31%	73%
A0A3R7N5S4	Trypanosoma rangeli	33%	78%
A0A3R7NKI8	Trypanosoma rangeli	31%	95%
A0A3R7RLL1	Trypanosoma rangeli	27%	68%
A0A3S5H5G0	Leishmania donovani	26%	100%
A0A3S5H789	Leishmania donovani	25%	100%
A0A3S7WRG1	Leishmania donovani	25%	100%
A0A3S7WTN9	Leishmania donovani	33%	77%
A0A3S7WUX5	Leishmania donovani	66%	100%
A0A3S7WVE9	Leishmania donovani	32%	100%
A0A3S7WWE7	Leishmania donovani	26%	100%
A0A3S7WWL1	Leishmania donovani	26%	99%
A0A3S7X123	Leishmania donovani	26%	100%
A0A3S7X2W9	Leishmania donovani	26%	100%
A0A3S7X6T8	Leishmania donovani	31%	66%
A0A3S7X7D5	Leishmania donovani	25%	100%
A0A3S7X9R4	Leishmania donovani	35%	80%
A0A3S7X9S2	Leishmania donovani	36%	87%
A0A3S7XA45	Leishmania donovani	33%	76%
A0A422MYB4	Trypanosoma rangeli	36%	94%
A0A422NJ21	Trypanosoma rangeli	61%	100%
A0A422NJ30	Trypanosoma rangeli	62%	100%
A0A422NUF0	Trypanosoma rangeli	30%	74%
A0A422P0J2	Trypanosoma rangeli	38%	88%
A0A422P0N6	Trypanosoma rangeli	29%	95%
A0A422P1R5	Trypanosoma rangeli	33%	96%
A0A422P270	Trypanosoma rangeli	29%	67%
A0A451EJH2	Leishmania donovani	25%	100%
A0A8I3S724	Canis lupus familiaris	36%	73%
A2YNT8	Oryza sativa subsp. indica	43%	87%
A2ZAB5	Oryza sativa subsp. indica	41%	89%
A3B529	Oryza sativa subsp. japonica	52%	68%
A4H3D2	Leishmania braziliensis	25%	100%
A4H459	Leishmania braziliensis	26%	100%
A4H539	Leishmania braziliensis	96%	100%
A4H601	Leishmania braziliensis	29%	100%
A4H641	Leishmania braziliensis	26%	100%
A4H8C4	Leishmania braziliensis	32%	100%
A4H9H4	Leishmania braziliensis	65%	100%
A4H9L8	Leishmania braziliensis	33%	100%
A4H9X2	Leishmania braziliensis	32%	100%
A4H9X5	Leishmania braziliensis	25%	100%
A4HA94	Leishmania braziliensis	29%	100%
A4HAC8	Leishmania braziliensis	24%	100%
A4HBL4	Leishmania braziliensis	26%	100%
A4HBW8	Leishmania braziliensis	27%	99%
A4HCD7	Leishmania braziliensis	38%	69%
A4HCE6	Leishmania braziliensis	33%	100%
A4HED7	Leishmania braziliensis	33%	100%
A4HEL2	Leishmania braziliensis	26%	100%
A4HFI2	Leishmania braziliensis	27%	100%
A4HG26	Leishmania braziliensis	24%	100%
A4HG92	Leishmania braziliensis	33%	100%
A4HHS9	Leishmania braziliensis	26%	100%
A4HIM5	Leishmania braziliensis	25%	100%
A4HJT5	Leishmania braziliensis	31%	67%
A4HJW2	Leishmania braziliensis	32%	69%
A4HLJ9	Leishmania braziliensis	24%	100%
A4HLR0	Leishmania braziliensis	32%	66%
A4HN71	Leishmania braziliensis	35%	100%
A4HNG3	Leishmania braziliensis	32%	100%
A4HNR5	Leishmania braziliensis	29%	100%
A4HQG8	Leishmania braziliensis	25%	100%
A4HRN3	Leishmania infantum	25%	100%
A4HSE2	Leishmania infantum	26%	100%
A4HTB4	Leishmania infantum	100%	100%
A4HUC8	Leishmania infantum	28%	100%
A4HUS3	Leishmania infantum	25%	100%
A4HWP5	Leishmania infantum	33%	100%
A4HXU0	Leishmania infantum	66%	100%
A4HXY2	Leishmania infantum	33%	100%
A4HYH4	Leishmania infantum	30%	100%
A4HYX6	Leishmania infantum	25%	100%
A4HZA2	Leishmania infantum	26%	100%
A4HZV1	Leishmania infantum	38%	100%
A4HZW8	Leishmania infantum	34%	100%
A4I1T4	Leishmania infantum	33%	100%
A4I1U3	Leishmania infantum	25%	99%
A4I3C6	Leishmania infantum	33%	100%
A4I4Y0	Leishmania infantum	26%	100%
A4I7A1	Leishmania infantum	30%	67%
A4I7C4	Leishmania infantum	32%	69%
A4I910	Leishmania infantum	23%	100%
A4I960	Leishmania infantum	31%	66%
A4I9H1	Leishmania infantum	25%	100%
A4IBT4	Leishmania infantum	35%	100%
A4IBT9	Leishmania infantum	35%	100%
A4IC54	Leishmania infantum	33%	100%
A4ICT0	Leishmania infantum	29%	100%
A4IGM9	Xenopus tropicalis	36%	82%
A5GFW1	Sus scrofa	36%	74%
A8X6H4	Caenorhabditis briggsae	42%	83%
A8XJQ6	Caenorhabditis briggsae	33%	77%
A8XW88	Caenorhabditis briggsae	34%	79%
A9TF79	Physcomitrium patens	42%	85%
C9ZKE1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	73%
C9ZL78	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	70%
C9ZMH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	67%
C9ZSI7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	97%
C9ZUK8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	100%
C9ZWI1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	69%
C9ZXP1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	76%
C9ZYF0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	81%
C9ZYS7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	75%
C9ZYT4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	74%
C9ZZX0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	100%
C9ZZX1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	100%
D0A2M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	95%
D0A5C6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	88%
D0A820	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	92%
D7UQM5	Patiria pectinifera	38%	73%
E9ACB1	Leishmania major	25%	100%
E9ACW6	Leishmania major	25%	100%
E9AD33	Leishmania major	27%	100%
E9AED4	Leishmania major	27%	100%
E9AFM1	Leishmania major	35%	100%
E9AFX4	Leishmania major	32%	100%
E9AGR7	Leishmania infantum	32%	100%
E9AGS0	Leishmania infantum	24%	100%
E9AGX6	Leishmania infantum	26%	99%
E9AJJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AKB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ALA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
E9ALF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AN28	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9ANF7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AQF3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ARK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
E9ARP5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9ARW6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AS98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ASH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AUS3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AUY2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AV92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	99%
E9AVR5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AVS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AXW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AXY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	99%
E9AYV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AZF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AZL3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	67%
E9B2B7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	69%
E9B3X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B436	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	66%
E9B4G9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B6S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B6S9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B727	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
O01427	Caenorhabditis elegans	40%	97%
O08875	Rattus norvegicus	40%	68%
O14965	Homo sapiens	35%	73%
O22932	Arabidopsis thaliana	51%	68%
O54784	Mus musculus	35%	66%
O54863	Mus musculus	36%	83%
O55099	Rattus norvegicus	35%	86%
O59697	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	70%
O59790	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	83%
O64629	Arabidopsis thaliana	35%	100%
O64812	Arabidopsis thaliana	41%	87%
O65554	Arabidopsis thaliana	53%	67%
O70126	Mus musculus	35%	86%
O70150	Rattus norvegicus	40%	86%
O80902	Arabidopsis thaliana	48%	69%
O88445	Mus musculus	36%	100%
O88764	Rattus norvegicus	35%	66%
O96526	Leishmania major	29%	100%
P00517	Bos taurus	36%	84%
P05131	Bos taurus	35%	84%
P05132	Mus musculus	35%	84%
P05383	Sus scrofa	35%	84%
P05986	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	74%
P06244	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	75%
P06245	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	78%
P0C5D6	Oryza sativa subsp. japonica	41%	89%
P11801	Homo sapiens	37%	70%
P12370	Drosophila melanogaster	35%	84%
P16911	Drosophila melanogaster	34%	84%
P17612	Homo sapiens	36%	84%
P21137	Caenorhabditis elegans	33%	73%
P22612	Homo sapiens	34%	84%
P22694	Homo sapiens	35%	84%
P25321	Cricetulus griseus	35%	84%
P25323	Dictyostelium discoideum	39%	100%
P27791	Rattus norvegicus	35%	84%
P36887	Sus scrofa	36%	84%
P38991	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	81%
P43291	Arabidopsis thaliana	41%	82%
P43292	Arabidopsis thaliana	40%	84%
P49673	Ascaris suum	34%	88%
P51817	Homo sapiens	35%	83%
P54644	Dictyostelium discoideum	35%	67%
P59241	Rattus norvegicus	36%	75%
P68180	Cricetulus griseus	35%	84%
P68181	Mus musculus	35%	84%
P68182	Rattus norvegicus	35%	84%
P92937	Arabidopsis thaliana	52%	70%
P97477	Mus musculus	34%	75%
Q00771	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	71%
Q02066	Triticum aestivum	42%	89%
Q09136	Sus scrofa	40%	77%
Q0D4J7	Oryza sativa subsp. japonica	42%	87%
Q0V7M1	Bos taurus	37%	70%
Q14012	Homo sapiens	40%	80%
Q27687	Leishmania major	33%	100%
Q2QY53	Oryza sativa subsp. japonica	54%	68%
Q2QYM3	Oryza sativa subsp. japonica	50%	67%
Q2RBF0	Oryza sativa subsp. japonica	50%	68%
Q2TA06	Bos taurus	36%	74%
Q2V452	Arabidopsis thaliana	53%	67%
Q39192	Arabidopsis thaliana	41%	82%
Q39193	Arabidopsis thaliana	41%	82%
Q3SZW1	Bos taurus	40%	81%
Q4KTY1	Pinctada fucata	37%	71%
Q4Q3K6	Leishmania major	26%	100%
Q4Q3Y9	Leishmania major	32%	66%
Q4Q449	Leishmania major	23%	100%
Q4Q5T9	Leishmania major	32%	69%
Q4Q5W2	Leishmania major	30%	67%
Q4Q9I7	Leishmania major	25%	99%
Q4Q9K2	Leishmania major	33%	100%
Q4QBQ2	Leishmania major	34%	100%
Q4QBR6	Leishmania major	38%	100%
Q4QC88	Leishmania major	26%	99%
Q4QCK0	Leishmania major	25%	100%
Q4QCR2	Leishmania major	24%	100%
Q4QCR3	Leishmania major	24%	100%
Q4QD66	Leishmania major	30%	100%
Q4QDK3	Leishmania major	24%	100%
Q4QDK6	Leishmania major	32%	100%
Q4QDX7	Leishmania major	66%	100%
Q4QF23	Leishmania major	33%	100%
Q4QH69	Leishmania major	25%	100%
Q4QHJ8	Leishmania major	28%	100%
Q4QIJ7	Leishmania major	100%	100%
Q4QJJ0	Leishmania major	26%	100%
Q501V0	Danio rerio	37%	70%
Q54CY9	Dictyostelium discoideum	39%	95%
Q54SJ5	Dictyostelium discoideum	40%	95%
Q54WX4	Dictyostelium discoideum	37%	77%
Q5JLD8	Oryza sativa subsp. japonica	51%	66%
Q5N942	Oryza sativa subsp. japonica	42%	82%
Q61241	Mus musculus	39%	81%
Q61XD3	Caenorhabditis briggsae	39%	98%
Q63450	Rattus norvegicus	40%	79%
Q683C9	Arabidopsis thaliana	34%	100%
Q6A1A2	Homo sapiens	33%	75%
Q6BVA0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	34%	72%
Q6C3J2	Yarrowia lipolytica (strain CLIB 122 / E 150)	39%	80%
Q6CWQ4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	82%
Q6DE08	Xenopus laevis	35%	82%
Q6ERS0	Oryza sativa subsp. japonica	52%	73%
Q6FV07	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	34%	83%
Q6GPL3	Xenopus laevis	36%	80%
Q6NW76	Danio rerio	36%	92%
Q6P2M8	Homo sapiens	40%	86%
Q6SA08	Homo sapiens	34%	90%
Q6ZI44	Oryza sativa subsp. japonica	43%	81%
Q755C4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	33%	81%
Q75GK4	Oryza sativa subsp. japonica	48%	66%
Q75H77	Oryza sativa subsp. japonica	43%	82%
Q75LR7	Oryza sativa subsp. japonica	43%	87%
Q75V57	Oryza sativa subsp. japonica	44%	82%
Q7JP68	Caenorhabditis elegans	33%	74%
Q7X996	Oryza sativa subsp. japonica	54%	67%
Q7XIW5	Oryza sativa subsp. japonica	44%	67%
Q7XKA8	Oryza sativa subsp. japonica	43%	80%
Q7XQP4	Oryza sativa subsp. japonica	42%	82%
Q7Y0B9	Oryza sativa subsp. japonica	41%	80%
Q7YRC6	Bos taurus	35%	86%
Q84VQ3	Arabidopsis thaliana	52%	67%
Q869W6	Dictyostelium discoideum	41%	85%
Q86AD7	Dictyostelium discoideum	37%	76%
Q8BHI9	Mus musculus	37%	68%
Q8BW96	Mus musculus	39%	77%
Q8IU85	Homo sapiens	39%	77%
Q8IY84	Homo sapiens	38%	68%
Q8LIG4	Oryza sativa subsp. japonica	52%	67%
Q8MJ44	Canis lupus familiaris	36%	85%
Q8RWC9	Arabidopsis thaliana	51%	67%
Q8VDF3	Mus musculus	35%	80%
Q8WQ45	Leishmania donovani	29%	95%
Q91819	Xenopus laevis	37%	73%
Q91820	Xenopus laevis	37%	73%
Q91YA2	Mus musculus	37%	70%
Q91YS8	Mus musculus	40%	79%
Q922R0	Mus musculus	34%	83%
Q940H6	Arabidopsis thaliana	43%	82%
Q94C40	Arabidopsis thaliana	47%	69%
Q94CG0	Arabidopsis thaliana	44%	71%
Q96GD4	Homo sapiens	36%	86%
Q96PF2	Homo sapiens	36%	83%
Q96PN8	Homo sapiens	39%	100%
Q96QS6	Homo sapiens	36%	77%
Q9BXA7	Homo sapiens	39%	81%
Q9C958	Arabidopsis thaliana	41%	82%
Q9D2E1	Mus musculus	39%	100%
Q9D411	Mus musculus	34%	90%
Q9FFP9	Arabidopsis thaliana	42%	82%
Q9FJ54	Arabidopsis thaliana	48%	67%
Q9GNR4	Leishmania major	35%	100%
Q9LDI3	Arabidopsis thaliana	52%	66%
Q9LEU7	Arabidopsis thaliana	55%	67%
Q9LZW4	Arabidopsis thaliana	51%	67%
Q9M077	Arabidopsis thaliana	34%	100%
Q9M9E9	Arabidopsis thaliana	39%	86%
Q9MAM1	Arabidopsis thaliana	54%	66%
Q9MZD9	Ovis aries	36%	84%
Q9N0X0	Sus scrofa	36%	86%
Q9N2N1	Leishmania major	33%	100%
Q9P7I2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	88%
Q9QYK9	Mus musculus	40%	86%
Q9SMQ4	Arabidopsis thaliana	42%	85%
Q9SPK4	Arabidopsis thaliana	36%	100%
Q9STV4	Arabidopsis thaliana	52%	67%
Q9SUL7	Arabidopsis thaliana	51%	69%
Q9TXJ0	Caenorhabditis elegans	40%	85%
Q9U6V4	Leishmania donovani	30%	100%
Q9UIK4	Homo sapiens	35%	80%
Q9UQB9	Homo sapiens	37%	96%
Q9VKN7	Drosophila melanogaster	36%	90%
Q9XIW0	Arabidopsis thaliana	49%	69%
Q9Y899	Emericella nidulans	37%	73%
V5B871	Trypanosoma cruzi	34%	69%
V5BAZ8	Trypanosoma cruzi	33%	77%
V5BC61	Trypanosoma cruzi	31%	95%
V5BCH2	Trypanosoma cruzi	30%	76%
V5BEK5	Trypanosoma cruzi	36%	88%
V5BFK9	Trypanosoma cruzi	27%	100%
V5BG98	Trypanosoma cruzi	32%	96%
V5BNV8	Trypanosoma cruzi	78%	100%
V5BPE2	Trypanosoma cruzi	32%	81%
V5BQH6	Trypanosoma cruzi	29%	68%
V5BV49	Trypanosoma cruzi	29%	95%
V5BWC2	Trypanosoma cruzi	63%	100%
V5D579	Trypanosoma cruzi	30%	69%
V5DI55	Trypanosoma cruzi	33%	71%
V5DMJ4	Trypanosoma cruzi	37%	87%
V5DPP5	Trypanosoma cruzi	27%	69%
W0LYS5	Macrobrachium nipponense	41%	86%