ATP-dependent DEAD/H RNA helicase, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase DBP2B, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H5X3_LEIDO

TriTrypDb:

LdBPK_070130.1 , LdCL_070008700 , LDHU3_36.2940

Length:

544

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005730	nucleolus	5	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	2
GO:1990904	ribonucleoprotein complex	2	1
GO:0016020	membrane	2	1

Expansion

Sequence features

A0A3S5H5X3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5X3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	13
GO:0003676	nucleic acid binding	3	13
GO:0003724	RNA helicase activity	3	12
GO:0003743	translation initiation factor activity	4	11
GO:0003824	catalytic activity	1	13
GO:0004386	helicase activity	2	13
GO:0005488	binding	1	13
GO:0005524	ATP binding	5	13
GO:0008135	translation factor activity, RNA binding	3	11
GO:0008186	ATP-dependent activity, acting on RNA	2	12
GO:0016787	hydrolase activity	2	13
GO:0017076	purine nucleotide binding	4	13
GO:0030554	adenyl nucleotide binding	5	13
GO:0032553	ribonucleotide binding	3	13
GO:0032555	purine ribonucleotide binding	4	13
GO:0032559	adenyl ribonucleotide binding	5	13
GO:0035639	purine ribonucleoside triphosphate binding	4	13
GO:0036094	small molecule binding	2	13
GO:0043167	ion binding	2	13
GO:0043168	anion binding	3	13
GO:0045182	translation regulator activity	1	11
GO:0090079	translation regulator activity, nucleic acid binding	2	11
GO:0097159	organic cyclic compound binding	2	13
GO:0097367	carbohydrate derivative binding	2	13
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	13
GO:0140657	ATP-dependent activity	1	13
GO:1901265	nucleoside phosphate binding	3	13
GO:1901363	heterocyclic compound binding	2	13
GO:0003723	RNA binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	3	7	PF00656	0.705
CLV_NRD_NRD_1	229	231	PF00675	0.319
CLV_NRD_NRD_1	305	307	PF00675	0.310
CLV_NRD_NRD_1	428	430	PF00675	0.321
CLV_PCSK_SKI1_1	230	234	PF00082	0.318
CLV_PCSK_SKI1_1	433	437	PF00082	0.353
CLV_PCSK_SKI1_1	477	481	PF00082	0.616
CLV_PCSK_SKI1_1	499	503	PF00082	0.498
CLV_PCSK_SKI1_1	96	100	PF00082	0.639
CLV_Separin_Metazoa	374	378	PF03568	0.615
DEG_APCC_DBOX_1	229	237	PF00400	0.519
DEG_ODPH_VHL_1	483	495	PF01847	0.429
DEG_SCF_FBW7_1	159	164	PF00400	0.422
DOC_CKS1_1	265	270	PF01111	0.510
DOC_CYCLIN_RxL_1	377	390	PF00134	0.521
DOC_CYCLIN_RxL_1	496	506	PF00134	0.745
DOC_MAPK_gen_1	255	265	PF00069	0.532
DOC_MAPK_gen_1	313	321	PF00069	0.510
DOC_MAPK_gen_1	403	412	PF00069	0.615
DOC_MAPK_gen_1	427	437	PF00069	0.529
DOC_MAPK_MEF2A_6	130	138	PF00069	0.467
DOC_MAPK_MEF2A_6	258	265	PF00069	0.510
DOC_MAPK_MEF2A_6	338	345	PF00069	0.412
DOC_PP1_RVXF_1	381	388	PF00149	0.510
DOC_PP1_RVXF_1	86	92	PF00149	0.520
DOC_PP2B_LxvP_1	141	144	PF13499	0.453
DOC_PP4_FxxP_1	103	106	PF00568	0.602
DOC_PP4_FxxP_1	156	159	PF00568	0.575
DOC_PP4_FxxP_1	190	193	PF00568	0.510
DOC_USP7_MATH_1	161	165	PF00917	0.519
DOC_USP7_MATH_1	485	489	PF00917	0.734
DOC_USP7_MATH_1	517	521	PF00917	0.539
DOC_USP7_MATH_1	529	533	PF00917	0.467
DOC_USP7_MATH_1	534	538	PF00917	0.589
DOC_WW_Pin1_4	157	162	PF00397	0.502
DOC_WW_Pin1_4	245	250	PF00397	0.562
DOC_WW_Pin1_4	264	269	PF00397	0.410
DOC_WW_Pin1_4	512	517	PF00397	0.703
LIG_14-3-3_CanoR_1	284	288	PF00244	0.510
LIG_14-3-3_CanoR_1	316	320	PF00244	0.523
LIG_14-3-3_CanoR_1	406	410	PF00244	0.620
LIG_14-3-3_CanoR_1	477	482	PF00244	0.592
LIG_Actin_WH2_2	268	286	PF00022	0.519
LIG_ActinCP_TwfCPI_2	103	110	PF01115	0.644
LIG_APCC_ABBA_1	124	129	PF00400	0.437
LIG_APCC_ABBA_1	410	415	PF00400	0.510
LIG_BIR_II_1	1	5	PF00653	0.702
LIG_FHA_1	216	222	PF00498	0.510
LIG_FHA_1	239	245	PF00498	0.519
LIG_FHA_1	278	284	PF00498	0.517
LIG_FHA_1	478	484	PF00498	0.573
LIG_FHA_2	287	293	PF00498	0.640
LIG_LIR_Apic_2	153	159	PF02991	0.494
LIG_LIR_Apic_2	187	193	PF02991	0.510
LIG_LIR_Apic_2	19	25	PF02991	0.615
LIG_LIR_Apic_2	27	33	PF02991	0.570
LIG_LIR_Gen_1	137	146	PF02991	0.535
LIG_LIR_Gen_1	286	293	PF02991	0.517
LIG_LIR_Gen_1	339	345	PF02991	0.416
LIG_LIR_Gen_1	488	497	PF02991	0.640
LIG_LIR_Gen_1	90	98	PF02991	0.502
LIG_LIR_Nem_3	137	141	PF02991	0.530
LIG_LIR_Nem_3	164	170	PF02991	0.534
LIG_LIR_Nem_3	286	290	PF02991	0.517
LIG_LIR_Nem_3	339	343	PF02991	0.417
LIG_LIR_Nem_3	474	479	PF02991	0.648
LIG_LIR_Nem_3	488	493	PF02991	0.568
LIG_LIR_Nem_3	90	94	PF02991	0.469
LIG_LIR_Nem_3	99	104	PF02991	0.517
LIG_MYND_1	202	206	PF01753	0.585
LIG_NRBOX	270	276	PF00104	0.530
LIG_Pex14_2	321	325	PF04695	0.510
LIG_Pex14_2	336	340	PF04695	0.431
LIG_SH2_CRK	22	26	PF00017	0.612
LIG_SH2_CRK	30	34	PF00017	0.530
LIG_SH2_CRK	457	461	PF00017	0.585
LIG_SH2_STAT3	104	107	PF00017	0.523
LIG_SH2_STAT5	287	290	PF00017	0.519
LIG_SH2_STAT5	423	426	PF00017	0.530
LIG_SH2_STAT5	466	469	PF00017	0.515
LIG_SH2_STAT5	490	493	PF00017	0.684
LIG_SH3_3	103	109	PF00018	0.653
LIG_SH3_3	128	134	PF00018	0.450
LIG_SH3_3	162	168	PF00018	0.615
LIG_SH3_3	200	206	PF00018	0.521
LIG_SH3_3	211	217	PF00018	0.514
LIG_SH3_3	246	252	PF00018	0.519
LIG_SUMO_SIM_anti_2	450	455	PF11976	0.548
LIG_SUMO_SIM_par_1	166	173	PF11976	0.511
LIG_SUMO_SIM_par_1	270	277	PF11976	0.530
LIG_SUMO_SIM_par_1	477	482	PF11976	0.614
LIG_TRAF2_1	111	114	PF00917	0.591
LIG_TRAF2_2	203	208	PF00917	0.615
LIG_TYR_ITIM	285	290	PF00017	0.519
LIG_WRC_WIRS_1	524	529	PF05994	0.621
MOD_CDK_SPK_2	245	250	PF00069	0.562
MOD_CDK_SPxK_1	264	270	PF00069	0.510
MOD_CK1_1	184	190	PF00069	0.510
MOD_CK1_1	238	244	PF00069	0.578
MOD_CK1_1	532	538	PF00069	0.504
MOD_CK2_1	108	114	PF00069	0.505
MOD_CK2_1	286	292	PF00069	0.576
MOD_GlcNHglycan	13	16	PF01048	0.672
MOD_GlcNHglycan	183	186	PF01048	0.315
MOD_GlcNHglycan	321	324	PF01048	0.310
MOD_GlcNHglycan	519	522	PF01048	0.603
MOD_GlcNHglycan	52	55	PF01048	0.690
MOD_GlcNHglycan	536	539	PF01048	0.723
MOD_GSK3_1	157	164	PF00069	0.373
MOD_GSK3_1	231	238	PF00069	0.572
MOD_GSK3_1	307	314	PF00069	0.521
MOD_GSK3_1	315	322	PF00069	0.495
MOD_GSK3_1	485	492	PF00069	0.705
MOD_GSK3_1	511	518	PF00069	0.781
MOD_GSK3_1	523	530	PF00069	0.525
MOD_N-GLC_1	277	282	PF02516	0.415
MOD_NEK2_1	274	279	PF00069	0.534
MOD_NEK2_1	283	288	PF00069	0.496
MOD_NEK2_1	319	324	PF00069	0.517
MOD_NEK2_1	332	337	PF00069	0.428
MOD_NEK2_1	387	392	PF00069	0.520
MOD_NEK2_1	405	410	PF00069	0.615
MOD_NEK2_1	479	484	PF00069	0.579
MOD_NEK2_1	533	538	PF00069	0.517
MOD_PIKK_1	307	313	PF00454	0.530
MOD_PIKK_1	96	102	PF00454	0.531
MOD_PK_1	120	126	PF00069	0.595
MOD_PK_1	235	241	PF00069	0.562
MOD_PKA_2	283	289	PF00069	0.518
MOD_PKA_2	315	321	PF00069	0.521
MOD_PKA_2	405	411	PF00069	0.615
MOD_Plk_1	120	126	PF00069	0.595
MOD_Plk_4	114	120	PF00069	0.625
MOD_Plk_4	235	241	PF00069	0.615
MOD_Plk_4	283	289	PF00069	0.530
MOD_Plk_4	315	321	PF00069	0.511
MOD_Plk_4	405	411	PF00069	0.585
MOD_Plk_4	485	491	PF00069	0.660
MOD_Plk_4	523	529	PF00069	0.735
MOD_ProDKin_1	157	163	PF00069	0.406
MOD_ProDKin_1	245	251	PF00069	0.562
MOD_ProDKin_1	264	270	PF00069	0.410
MOD_ProDKin_1	512	518	PF00069	0.701
MOD_SUMO_rev_2	364	372	PF00179	0.607
TRG_DiLeu_BaEn_1	137	142	PF01217	0.554
TRG_DiLeu_BaEn_1	432	437	PF01217	0.615
TRG_DiLeu_BaLyEn_6	267	272	PF01217	0.510
TRG_ENDOCYTIC_2	287	290	PF00928	0.519
TRG_ENDOCYTIC_2	490	493	PF00928	0.703
TRG_NES_CRM1_1	450	465	PF08389	0.572
TRG_Pf-PMV_PEXEL_1	219	224	PF00026	0.310
TRG_Pf-PMV_PEXEL_1	403	407	PF00026	0.426

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4X4	Leptomonas seymouri	30%	78%
A0A0N0P7D9	Leptomonas seymouri	92%	100%
A0A0N0P7N8	Leptomonas seymouri	51%	96%
A0A0N1I5R1	Leptomonas seymouri	25%	69%
A0A0N1I7N1	Leptomonas seymouri	37%	87%
A0A0N1PDE7	Leptomonas seymouri	31%	94%
A0A0S4IKX9	Bodo saltans	27%	72%
A0A0S4ITZ4	Bodo saltans	66%	100%
A0A0S4IX79	Bodo saltans	27%	75%
A0A0S4JSZ9	Bodo saltans	30%	90%
A0A0S4JT14	Bodo saltans	54%	95%
A0A0S4KKU4	Bodo saltans	30%	78%
A0A1X0NP86	Trypanosomatidae	68%	100%
A0A1X0NQS6	Trypanosomatidae	36%	100%
A0A1X0NVD0	Trypanosomatidae	33%	95%
A0A1X0P0F9	Trypanosomatidae	32%	100%
A0A1X0P2M8	Trypanosomatidae	32%	85%
A0A1X0P5C7	Trypanosomatidae	39%	69%
A0A1X0P6S6	Trypanosomatidae	39%	83%
A0A1X0P8K3	Trypanosomatidae	53%	89%
A0A3Q8IC45	Leishmania donovani	28%	100%
A0A3Q8ID91	Leishmania donovani	34%	100%
A0A3Q8IDY0	Leishmania donovani	32%	100%
A0A3Q8IEU7	Leishmania donovani	28%	100%
A0A3Q8IF94	Leishmania donovani	40%	89%
A0A3Q8IQY6	Leishmania donovani	53%	100%
A0A3R7K6G7	Trypanosoma rangeli	74%	100%
A0A3R7KKL1	Trypanosoma rangeli	29%	76%
A0A3R7N322	Trypanosoma rangeli	39%	90%
A0A3R7RJV1	Trypanosoma rangeli	30%	98%
A0A3S5H4X0	Leishmania donovani	33%	100%
A0A3S7WQ33	Leishmania donovani	35%	79%
A0A3S7WR01	Leishmania donovani	24%	70%
A0A3S7X579	Leishmania donovani	31%	93%
A0A422MXD2	Trypanosoma rangeli	40%	68%
A0A422N502	Trypanosoma rangeli	54%	93%
A0A422NDK5	Trypanosoma rangeli	32%	100%
A1C5V3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	41%	100%
A1C6C4	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	51%	99%
A1CH78	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	39%	80%
A1CHL3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	36%	68%
A1CX72	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	36%	68%
A1CXK7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	43%	80%
A1DG51	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	42%	100%
A1DGZ7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	49%	100%
A2QC74	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	50%	96%
A2QFL3	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	40%	100%
A2QI25	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	43%	80%
A2QIL2	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	67%
A3LNL1	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	34%	100%
A3LQW7	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	51%	100%
A3LRW2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	45%	100%
A4H4Y0	Leishmania braziliensis	98%	90%
A4H5Z5	Leishmania braziliensis	22%	75%
A4HC04	Leishmania braziliensis	28%	100%
A4HGK6	Leishmania braziliensis	33%	100%
A4HGR1	Leishmania braziliensis	33%	100%
A4HK20	Leishmania braziliensis	38%	100%
A4HK38	Leishmania braziliensis	30%	93%
A4HKL3	Leishmania braziliensis	28%	71%
A4HP82	Leishmania braziliensis	53%	100%
A4HRK0	Leishmania infantum	33%	100%
A4HT33	Leishmania infantum	100%	100%
A4HTF8	Leishmania infantum	35%	79%
A4HUC1	Leishmania infantum	23%	70%
A4HZF8	Leishmania infantum	28%	100%
A4I3N2	Leishmania infantum	32%	100%
A4I3T6	Leishmania infantum	34%	100%
A4I7K4	Leishmania infantum	40%	89%
A4I7M5	Leishmania infantum	31%	93%
A4IAT7	Leishmania infantum	28%	100%
A4IDI7	Leishmania infantum	53%	100%
A4QSS5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	51%	99%
A4RHF1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	40%	81%
A4RK80	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	37%	81%
A5A6J2	Pan troglodytes	47%	89%
A5DAC8	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	44%	100%
A5DF03	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	32%	95%
A5DL80	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	51%	98%
A5DQF1	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	39%	100%
A5DS77	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	53%	99%
A5DU73	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	35%	91%
A5E1W4	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	42%	100%
A6QXC1	Ajellomyces capsulatus (strain NAm1 / WU24)	42%	100%
A6R3L3	Ajellomyces capsulatus (strain NAm1 / WU24)	40%	78%
A6RGE3	Ajellomyces capsulatus (strain NAm1 / WU24)	51%	100%
A6RJA2	Botryotinia fuckeliana (strain B05.10)	37%	69%
A6SCT6	Botryotinia fuckeliana (strain B05.10)	43%	92%
A6SEH9	Botryotinia fuckeliana (strain B05.10)	43%	80%
A6SFW7	Botryotinia fuckeliana (strain B05.10)	50%	100%
A6ZRX0	Saccharomyces cerevisiae (strain YJM789)	50%	100%
A6ZUA1	Saccharomyces cerevisiae (strain YJM789)	44%	100%
A6ZWD3	Saccharomyces cerevisiae (strain YJM789)	37%	88%
A7E449	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	51%	95%
A7EGG4	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	37%	67%
A7EJY3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	43%	80%
A7EYW0	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	44%	91%
A7TKR8	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	36%	84%
A7TTT5	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	46%	100%
C8V8H4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	81%
C9ZNU6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	85%
C9ZUS0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	96%
C9ZZ43	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	74%
D0A378	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	96%
D0A4H6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
D0A872	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A9S3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	98%
D0PV95	Caenorhabditis elegans	39%	77%
E9AEL4	Leishmania major	28%	100%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AL45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9AM86	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	79%
E9AN20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	74%
E9ASZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AZX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B2G1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	87%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	93%
E9B5S5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
G0SFM2	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	52%	98%
O13370	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	86%
O15523	Homo sapiens	39%	82%
O22907	Arabidopsis thaliana	42%	72%
O62591	Leishmania major	33%	100%
P0CQ74	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	41%	85%
P0CQ75	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	41%	85%
P0CQ76	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	52%	100%
P0CQ77	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	52%	100%
P0CQ78	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	41%	90%
P0CQ79	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	41%	90%
P0CQ88	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	74%
P0CQ89	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	74%
P17844	Homo sapiens	47%	89%
P19109	Drosophila melanogaster	48%	76%
P20447	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	44%	100%
P23394	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	93%
P24346	Xenopus laevis	37%	78%
P24782	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	99%
P24783	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	49%	100%
P24784	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	88%
P93008	Arabidopsis thaliana	39%	74%
Q0CL13	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	41%	100%
Q0CLJ6	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	43%	81%
Q0CLX0	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	35%	69%
Q0DB53	Oryza sativa subsp. japonica	38%	90%
Q0UWA6	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	40%	78%
Q0UWC8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	37%	73%
Q0UY62	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	44%	92%
Q10202	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	94%
Q10MH8	Oryza sativa subsp. japonica	44%	71%
Q1DJF0	Coccidioides immitis (strain RS)	40%	82%
Q1DMX8	Coccidioides immitis (strain RS)	35%	66%
Q1DP69	Coccidioides immitis (strain RS)	49%	100%
Q1DZK8	Coccidioides immitis (strain RS)	43%	100%
Q25225	Leishmania braziliensis	33%	100%
Q26696	Trypanosoma brucei brucei	53%	96%
Q2GUI4	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	41%	96%
Q2H720	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	51%	97%
Q2HEB0	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	36%	77%
Q2R1M8	Oryza sativa subsp. japonica	41%	87%
Q2U070	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	51%	98%
Q2UGK3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	43%	81%
Q2UH00	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	35%	68%
Q2UMH8	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	42%	100%
Q3EBD3	Arabidopsis thaliana	34%	100%
Q4I7F9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	36%	75%
Q4I7K4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	36%	81%
Q4IF76	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	52%	98%
Q4IJH1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	42%	94%
Q4JG17	Penaeus vannamei	41%	77%
Q4PDT1	Ustilago maydis (strain 521 / FGSC 9021)	44%	93%
Q4PHU9	Ustilago maydis (strain 521 / FGSC 9021)	50%	99%
Q4Q1K8	Leishmania major	53%	100%
Q4Q5M6	Leishmania major	32%	94%
Q4Q5P5	Leishmania major	37%	88%
Q4Q858	Leishmania major	35%	100%
Q4Q8B2	Leishmania major	32%	100%
Q4QC38	Leishmania major	28%	100%
Q4QIG1	Leishmania major	35%	79%
Q4QIQ9	Leishmania major	100%	100%
Q4R6M5	Macaca fascicularis	47%	89%
Q4WH83	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	42%	100%
Q4WP13	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	43%	81%
Q4WPE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	36%	68%
Q4X195	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	51%	99%
Q501J6	Mus musculus	49%	84%
Q53RK8	Oryza sativa subsp. japonica	40%	74%
Q54CE0	Dictyostelium discoideum	52%	69%
Q54KG1	Dictyostelium discoideum	38%	81%
Q59LU0	Candida albicans (strain SC5314 / ATCC MYA-2876)	53%	97%
Q59W52	Candida albicans (strain SC5314 / ATCC MYA-2876)	32%	94%
Q5APT8	Candida albicans (strain SC5314 / ATCC MYA-2876)	43%	96%
Q5AWA6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	43%	100%
Q5B0J9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	52%	97%
Q5BCU6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	36%	70%
Q5N7W4	Oryza sativa subsp. japonica	52%	82%
Q5QMN3	Oryza sativa subsp. japonica	55%	100%
Q5R4I9	Pongo abelii	48%	89%
Q5RC67	Pongo abelii	41%	66%
Q5Z6G5	Oryza sativa subsp. japonica	43%	88%
Q5ZBH5	Oryza sativa subsp. japonica	34%	92%
Q61656	Mus musculus	48%	89%
Q62095	Mus musculus	40%	83%
Q62167	Mus musculus	37%	82%
Q6BLU9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	34%	94%
Q6BP45	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	33%	99%
Q6BQ61	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	37%	100%
Q6BY27	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	50%	100%
Q6BZ77	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	43%	100%
Q6C024	Yarrowia lipolytica (strain CLIB 122 / E 150)	35%	95%
Q6C4D4	Yarrowia lipolytica (strain CLIB 122 / E 150)	50%	99%
Q6C9P3	Yarrowia lipolytica (strain CLIB 122 / E 150)	46%	100%
Q6CB69	Yarrowia lipolytica (strain CLIB 122 / E 150)	41%	88%
Q6CH58	Yarrowia lipolytica (strain CLIB 122 / E 150)	38%	100%
Q6CIV2	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	48%	98%
Q6CKI1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	35%	67%
Q6CT46	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	46%	100%
Q6CT49	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	100%
Q6FLF3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	48%	100%
Q6FML5	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	34%	67%
Q6FS54	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	44%	100%
Q6GVM6	Pan troglodytes	41%	82%
Q6Z4K6	Oryza sativa subsp. japonica	42%	85%
Q755A5	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	43%	100%
Q755N4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	48%	98%
Q75B50	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	37%	87%
Q75HJ0	Oryza sativa subsp. japonica	43%	85%
Q7S5R1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	89%
Q7SBC6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	97%
Q7SEL0	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	37%	75%
Q84W89	Arabidopsis thaliana	43%	86%
Q86TM3	Homo sapiens	38%	86%
Q8H136	Arabidopsis thaliana	50%	88%
Q8LA13	Arabidopsis thaliana	40%	89%
Q8SRB2	Encephalitozoon cuniculi (strain GB-M1)	45%	100%
Q8TFK8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	41%	88%
Q8W4R3	Arabidopsis thaliana	54%	92%
Q91VN6	Mus musculus	39%	87%
Q92841	Homo sapiens	48%	75%
Q9BUQ8	Homo sapiens	42%	66%
Q9C718	Arabidopsis thaliana	52%	100%
Q9FFQ1	Arabidopsis thaliana	35%	76%
Q9NXZ2	Homo sapiens	41%	84%
Q9P6U9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	39%	79%
Q9SZB4	Arabidopsis thaliana	38%	100%
Q9UJV9	Homo sapiens	39%	87%
Q9V3C0	Drosophila melanogaster	37%	88%
Q9VHP0	Drosophila melanogaster	38%	68%
Q9Y7T7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	82%
V5AST3	Trypanosoma cruzi	75%	100%
V5BAS2	Trypanosoma cruzi	30%	98%
V5CZW7	Trypanosoma cruzi	33%	100%
V5DKV2	Trypanosoma cruzi	32%	100%