Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S5H5W8_LEIDO

TriTrypDb:

LdBPK_070400.1 , LdCL_070007500 , LDHU3_07.0310

Length:

607

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	4

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Expansion

Sequence features

A0A3S5H5W8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5W8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	243	247	PF00656	0.396
CLV_NRD_NRD_1	231	233	PF00675	0.698
CLV_NRD_NRD_1	236	238	PF00675	0.669
CLV_NRD_NRD_1	271	273	PF00675	0.607
CLV_NRD_NRD_1	290	292	PF00675	0.599
CLV_NRD_NRD_1	303	305	PF00675	0.632
CLV_NRD_NRD_1	315	317	PF00675	0.566
CLV_NRD_NRD_1	33	35	PF00675	0.402
CLV_NRD_NRD_1	365	367	PF00675	0.707
CLV_NRD_NRD_1	394	396	PF00675	0.713

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE68	Leptomonas seymouri	54%	100%
A4H4W9	Leishmania braziliensis	80%	98%
A4HT42	Leishmania infantum	100%	100%
E9AL34	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QIS0	Leishmania major	94%	100%

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