LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S5H5W6_LEIDO
TriTrypDb:
LdBPK_070370.1 , LdCL_070007200 , LDHU3_07.0280
Length:
253

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H5W6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5W6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 159 161 PF00675 0.578
CLV_NRD_NRD_1 23 25 PF00675 0.660
CLV_PCSK_KEX2_1 159 161 PF00082 0.578
CLV_PCSK_KEX2_1 23 25 PF00082 0.661
CLV_Separin_Metazoa 183 187 PF03568 0.411
DEG_SCF_FBW7_1 84 91 PF00400 0.671
DOC_CKS1_1 85 90 PF01111 0.670
DOC_MAPK_MEF2A_6 137 145 PF00069 0.483
DOC_PP2B_LxvP_1 185 188 PF13499 0.528
DOC_PP4_FxxP_1 4 7 PF00568 0.695
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I988 Leptomonas seymouri 38% 100%
A4H4W5 Leishmania braziliensis 62% 97%
A4HT39 Leishmania infantum 98% 100%
E9AL31 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4QIS3 Leishmania major 89% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS