Methionine synthase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Methionine synthase

Gene product:

cobalamin-dependent methionine synthase, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H5V8_LEIDO

TriTrypDb:

LdBPK_070240.1 , LdCL_070005900 , LDHU3_07.0130

Length:

1252

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S5H5V8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5V8

Function

Biological processes
Term	Name	Level	Count
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0032259	methylation	2	8
GO:0042558	pteridine-containing compound metabolic process	4	8
GO:0044237	cellular metabolic process	2	8
GO:0046483	heterocycle metabolic process	3	8
GO:0071704	organic substance metabolic process	2	8
GO:1901360	organic cyclic compound metabolic process	3	8
GO:1901564	organonitrogen compound metabolic process	3	8
GO:0000096	sulfur amino acid metabolic process	4	1
GO:0000097	sulfur amino acid biosynthetic process	5	1
GO:0006082	organic acid metabolic process	3	1
GO:0006520	amino acid metabolic process	3	1
GO:0006555	methionine metabolic process	5	1
GO:0006790	sulfur compound metabolic process	3	1
GO:0008652	amino acid biosynthetic process	4	1
GO:0009058	biosynthetic process	2	1
GO:0009066	aspartate family amino acid metabolic process	5	1
GO:0009067	aspartate family amino acid biosynthetic process	6	1
GO:0009086	methionine biosynthetic process	6	1
GO:0016053	organic acid biosynthetic process	4	1
GO:0019752	carboxylic acid metabolic process	5	1
GO:0043436	oxoacid metabolic process	4	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044272	sulfur compound biosynthetic process	4	1
GO:0044281	small molecule metabolic process	2	1
GO:0044283	small molecule biosynthetic process	3	1
GO:0046394	carboxylic acid biosynthetic process	5	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1901605	alpha-amino acid metabolic process	4	1
GO:1901607	alpha-amino acid biosynthetic process	5	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0005488	binding	1	8
GO:0008168	methyltransferase activity	4	8
GO:0008172	S-methyltransferase activity	5	8
GO:0008270	zinc ion binding	6	8
GO:0008705	methionine synthase activity	6	8
GO:0016740	transferase activity	2	8
GO:0016741	transferase activity, transferring one-carbon groups	3	8
GO:0019842	vitamin binding	3	8
GO:0031419	cobalamin binding	4	8
GO:0036094	small molecule binding	2	8
GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	5	8
GO:0043167	ion binding	2	8
GO:0043169	cation binding	3	8
GO:0046872	metal ion binding	4	8
GO:0046906	tetrapyrrole binding	3	8
GO:0046914	transition metal ion binding	5	8
GO:0097159	organic cyclic compound binding	2	8
GO:1901363	heterocyclic compound binding	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	108	110	PF00675	0.287
CLV_NRD_NRD_1	1232	1234	PF00675	0.287
CLV_NRD_NRD_1	131	133	PF00675	0.325
CLV_NRD_NRD_1	481	483	PF00675	0.345
CLV_NRD_NRD_1	948	950	PF00675	0.541
CLV_PCSK_FUR_1	768	772	PF00082	0.610
CLV_PCSK_KEX2_1	1002	1004	PF00082	0.287
CLV_PCSK_KEX2_1	108	110	PF00082	0.287
CLV_PCSK_KEX2_1	131	133	PF00082	0.287
CLV_PCSK_KEX2_1	21	23	PF00082	0.558
CLV_PCSK_KEX2_1	379	381	PF00082	0.399
CLV_PCSK_KEX2_1	481	483	PF00082	0.345
CLV_PCSK_KEX2_1	509	511	PF00082	0.345
CLV_PCSK_KEX2_1	770	772	PF00082	0.399
CLV_PCSK_KEX2_1	845	847	PF00082	0.321
CLV_PCSK_PC1ET2_1	1002	1004	PF00082	0.287
CLV_PCSK_PC1ET2_1	21	23	PF00082	0.545
CLV_PCSK_PC1ET2_1	379	381	PF00082	0.399
CLV_PCSK_PC1ET2_1	509	511	PF00082	0.345
CLV_PCSK_PC1ET2_1	770	772	PF00082	0.399
CLV_PCSK_PC1ET2_1	845	847	PF00082	0.321
CLV_PCSK_PC7_1	127	133	PF00082	0.321
CLV_PCSK_SKI1_1	1002	1006	PF00082	0.287
CLV_PCSK_SKI1_1	1050	1054	PF00082	0.347
CLV_PCSK_SKI1_1	131	135	PF00082	0.325
CLV_PCSK_SKI1_1	158	162	PF00082	0.287
CLV_PCSK_SKI1_1	196	200	PF00082	0.287
CLV_PCSK_SKI1_1	21	25	PF00082	0.467
CLV_PCSK_SKI1_1	380	384	PF00082	0.345
CLV_PCSK_SKI1_1	50	54	PF00082	0.293
CLV_PCSK_SKI1_1	726	730	PF00082	0.287
CLV_PCSK_SKI1_1	737	741	PF00082	0.287
CLV_PCSK_SKI1_1	754	758	PF00082	0.539
CLV_PCSK_SKI1_1	770	774	PF00082	0.417
CLV_PCSK_SKI1_1	842	846	PF00082	0.325
DOC_CKS1_1	456	461	PF01111	0.399
DOC_CKS1_1	829	834	PF01111	0.487
DOC_CYCLIN_RxL_1	19	27	PF00134	0.450
DOC_CYCLIN_RxL_1	920	932	PF00134	0.499
DOC_CYCLIN_yCln2_LP_2	65	71	PF00134	0.576
DOC_MAPK_gen_1	1019	1029	PF00069	0.502
DOC_MAPK_gen_1	1063	1072	PF00069	0.490
DOC_MAPK_gen_1	383	393	PF00069	0.399
DOC_MAPK_gen_1	481	489	PF00069	0.345
DOC_MAPK_gen_1	506	516	PF00069	0.345
DOC_MAPK_gen_1	737	747	PF00069	0.487
DOC_MAPK_gen_1	845	853	PF00069	0.487
DOC_MAPK_gen_1	920	929	PF00069	0.488
DOC_MAPK_gen_1	947	956	PF00069	0.545
DOC_MAPK_MEF2A_6	1063	1072	PF00069	0.487
DOC_MAPK_MEF2A_6	209	218	PF00069	0.450
DOC_MAPK_MEF2A_6	243	252	PF00069	0.525
DOC_MAPK_MEF2A_6	740	747	PF00069	0.487
DOC_MAPK_MEF2A_6	786	793	PF00069	0.487
DOC_MAPK_MEF2A_6	846	855	PF00069	0.487
DOC_MAPK_MEF2A_6	931	939	PF00069	0.429
DOC_PP1_RVXF_1	923	930	PF00149	0.517
DOC_PP1_RVXF_1	934	940	PF00149	0.432
DOC_PP1_RVXF_1	965	971	PF00149	0.487
DOC_PP4_FxxP_1	1075	1078	PF00568	0.479
DOC_PP4_FxxP_1	849	852	PF00568	0.487
DOC_PP4_FxxP_1	992	995	PF00568	0.487
DOC_USP7_MATH_1	1017	1021	PF00917	0.547
DOC_USP7_MATH_1	1031	1035	PF00917	0.415
DOC_USP7_MATH_1	1200	1204	PF00917	0.490
DOC_USP7_MATH_1	562	566	PF00917	0.399
DOC_USP7_MATH_1	584	588	PF00917	0.345
DOC_USP7_MATH_1	595	599	PF00917	0.345
DOC_USP7_MATH_1	632	636	PF00917	0.460
DOC_USP7_MATH_1	658	662	PF00917	0.693
DOC_USP7_MATH_1	764	768	PF00917	0.628
DOC_USP7_MATH_1	858	862	PF00917	0.487
DOC_USP7_UBL2_3	1224	1228	PF12436	0.549
DOC_USP7_UBL2_3	379	383	PF12436	0.345
DOC_USP7_UBL2_3	38	42	PF12436	0.547
DOC_USP7_UBL2_3	50	54	PF12436	0.508
DOC_WW_Pin1_4	146	151	PF00397	0.487
DOC_WW_Pin1_4	318	323	PF00397	0.576
DOC_WW_Pin1_4	455	460	PF00397	0.399
DOC_WW_Pin1_4	6	11	PF00397	0.478
DOC_WW_Pin1_4	628	633	PF00397	0.462
DOC_WW_Pin1_4	828	833	PF00397	0.487
LIG_14-3-3_CanoR_1	1132	1141	PF00244	0.576
LIG_14-3-3_CanoR_1	1191	1199	PF00244	0.424
LIG_14-3-3_CanoR_1	158	163	PF00244	0.487
LIG_14-3-3_CanoR_1	326	336	PF00244	0.501
LIG_14-3-3_CanoR_1	630	639	PF00244	0.466
LIG_14-3-3_CanoR_1	667	672	PF00244	0.463
LIG_14-3-3_CanoR_1	674	680	PF00244	0.448
LIG_Actin_WH2_2	461	477	PF00022	0.399
LIG_APCC_ABBA_1	1039	1044	PF00400	0.487
LIG_APCC_ABBA_1	261	266	PF00400	0.511
LIG_APCC_ABBA_1	609	614	PF00400	0.471
LIG_APCC_ABBA_1	746	751	PF00400	0.467
LIG_APCC_ABBAyCdc20_2	8	14	PF00400	0.424
LIG_BIR_II_1	1	5	PF00653	0.652
LIG_BRCT_BRCA1_1	1213	1217	PF00533	0.487
LIG_BRCT_BRCA1_1	374	378	PF00533	0.345
LIG_BRCT_BRCA1_1	441	445	PF00533	0.345
LIG_BRCT_BRCA1_1	571	575	PF00533	0.345
LIG_BRCT_BRCA1_1	8	12	PF00533	0.442
LIG_CtBP_PxDLS_1	295	299	PF00389	0.525
LIG_deltaCOP1_diTrp_1	969	977	PF00928	0.487
LIG_EH_1	970	974	PF12763	0.470
LIG_eIF4E_1	101	107	PF01652	0.525
LIG_FHA_1	101	107	PF00498	0.525
LIG_FHA_1	1147	1153	PF00498	0.487
LIG_FHA_1	143	149	PF00498	0.487
LIG_FHA_1	172	178	PF00498	0.519
LIG_FHA_1	344	350	PF00498	0.449
LIG_FHA_1	356	362	PF00498	0.400
LIG_FHA_1	419	425	PF00498	0.345
LIG_FHA_1	456	462	PF00498	0.399
LIG_FHA_1	51	57	PF00498	0.525
LIG_FHA_1	829	835	PF00498	0.487
LIG_FHA_1	874	880	PF00498	0.467
LIG_FHA_1	951	957	PF00498	0.440
LIG_FHA_2	1044	1050	PF00498	0.510
LIG_FHA_2	1171	1177	PF00498	0.521
LIG_FHA_2	159	165	PF00498	0.487
LIG_FHA_2	186	192	PF00498	0.487
LIG_FHA_2	202	208	PF00498	0.487
LIG_FHA_2	219	225	PF00498	0.487
LIG_FHA_2	318	324	PF00498	0.525
LIG_FHA_2	534	540	PF00498	0.345
LIG_FHA_2	611	617	PF00498	0.459
LIG_FHA_2	905	911	PF00498	0.459
LIG_FHA_2	953	959	PF00498	0.456
LIG_FHA_2	964	970	PF00498	0.459
LIG_IRF3_LxIS_1	1068	1073	PF10401	0.576
LIG_LIR_Apic_2	1073	1078	PF02991	0.479
LIG_LIR_Gen_1	1067	1077	PF02991	0.488
LIG_LIR_Gen_1	1193	1204	PF02991	0.525
LIG_LIR_Gen_1	161	169	PF02991	0.487
LIG_LIR_Gen_1	187	198	PF02991	0.495
LIG_LIR_Gen_1	208	218	PF02991	0.487
LIG_LIR_Gen_1	236	247	PF02991	0.487
LIG_LIR_Gen_1	290	299	PF02991	0.579
LIG_LIR_Gen_1	421	431	PF02991	0.345
LIG_LIR_Gen_1	442	452	PF02991	0.345
LIG_LIR_Gen_1	797	806	PF02991	0.576
LIG_LIR_Gen_1	898	908	PF02991	0.482
LIG_LIR_Gen_1	9	19	PF02991	0.479
LIG_LIR_Nem_3	1053	1057	PF02991	0.510
LIG_LIR_Nem_3	1067	1072	PF02991	0.439
LIG_LIR_Nem_3	1108	1113	PF02991	0.480
LIG_LIR_Nem_3	1214	1219	PF02991	0.487
LIG_LIR_Nem_3	156	160	PF02991	0.487
LIG_LIR_Nem_3	161	165	PF02991	0.487
LIG_LIR_Nem_3	187	193	PF02991	0.495
LIG_LIR_Nem_3	208	214	PF02991	0.487
LIG_LIR_Nem_3	290	294	PF02991	0.579
LIG_LIR_Nem_3	375	381	PF02991	0.383
LIG_LIR_Nem_3	442	448	PF02991	0.345
LIG_LIR_Nem_3	572	578	PF02991	0.345
LIG_LIR_Nem_3	797	801	PF02991	0.576
LIG_LIR_Nem_3	898	904	PF02991	0.489
LIG_LIR_Nem_3	9	15	PF02991	0.435
LIG_LIR_Nem_3	906	911	PF02991	0.419
LIG_LIR_Nem_3	921	927	PF02991	0.364
LIG_LIR_Nem_3	969	973	PF02991	0.463
LIG_MLH1_MIPbox_1	1213	1217	PF16413	0.487
LIG_PCNA_PIPBox_1	715	724	PF02747	0.487
LIG_PCNA_yPIPBox_3	1043	1055	PF02747	0.521
LIG_Pex14_1	970	974	PF04695	0.487
LIG_Pex14_2	1122	1126	PF04695	0.525
LIG_Pex14_2	973	977	PF04695	0.487
LIG_Pex14_2	988	992	PF04695	0.487
LIG_PTB_Apo_2	156	163	PF02174	0.487
LIG_PTB_Apo_2	567	574	PF02174	0.345
LIG_PTB_Apo_2	968	975	PF02174	0.476
LIG_PTB_Apo_2	982	989	PF02174	0.512
LIG_PTB_Phospho_1	156	162	PF10480	0.487
LIG_REV1ctd_RIR_1	1052	1062	PF16727	0.525
LIG_SH2_CRK	1110	1114	PF00017	0.487
LIG_SH2_CRK	1157	1161	PF00017	0.487
LIG_SH2_CRK	157	161	PF00017	0.487
LIG_SH2_CRK	211	215	PF00017	0.487
LIG_SH2_CRK	512	516	PF00017	0.345
LIG_SH2_CRK	924	928	PF00017	0.384
LIG_SH2_NCK_1	211	215	PF00017	0.465
LIG_SH2_NCK_1	612	616	PF00017	0.454
LIG_SH2_NCK_1	78	82	PF00017	0.525
LIG_SH2_NCK_1	798	802	PF00017	0.465
LIG_SH2_SRC	162	165	PF00017	0.487
LIG_SH2_SRC	78	81	PF00017	0.517
LIG_SH2_SRC	908	911	PF00017	0.504
LIG_SH2_STAP1	162	166	PF00017	0.487
LIG_SH2_STAP1	169	173	PF00017	0.487
LIG_SH2_STAP1	512	516	PF00017	0.334
LIG_SH2_STAP1	544	548	PF00017	0.390
LIG_SH2_STAP1	641	645	PF00017	0.524
LIG_SH2_STAP1	959	963	PF00017	0.380
LIG_SH2_STAT3	101	104	PF00017	0.487
LIG_SH2_STAT3	1166	1169	PF00017	0.462
LIG_SH2_STAT3	169	172	PF00017	0.487
LIG_SH2_STAT5	1069	1072	PF00017	0.504
LIG_SH2_STAT5	1085	1088	PF00017	0.487
LIG_SH2_STAT5	1216	1219	PF00017	0.487
LIG_SH2_STAT5	169	172	PF00017	0.525
LIG_SH2_STAT5	211	214	PF00017	0.487
LIG_SH2_STAT5	264	267	PF00017	0.487
LIG_SH2_STAT5	275	278	PF00017	0.487
LIG_SH2_STAT5	356	359	PF00017	0.453
LIG_SH2_STAT5	612	615	PF00017	0.457
LIG_SH2_STAT5	915	918	PF00017	0.547
LIG_SH3_1	1161	1167	PF00018	0.487
LIG_SH3_3	1161	1167	PF00018	0.487
LIG_SH3_3	135	141	PF00018	0.547
LIG_SH3_3	149	155	PF00018	0.415
LIG_SH3_3	523	529	PF00018	0.429
LIG_SH3_3	742	748	PF00018	0.487
LIG_SH3_3	920	926	PF00018	0.529
LIG_SH3_3	937	943	PF00018	0.414
LIG_SH3_CIN85_PxpxPR_1	944	949	PF14604	0.529
LIG_Sin3_3	1023	1030	PF02671	0.525
LIG_SUMO_SIM_anti_2	1148	1154	PF11976	0.424
LIG_SUMO_SIM_anti_2	182	188	PF11976	0.511
LIG_SUMO_SIM_par_1	182	188	PF11976	0.525
LIG_SUMO_SIM_par_1	214	219	PF11976	0.525
LIG_SUMO_SIM_par_1	22	27	PF11976	0.402
LIG_SUMO_SIM_par_1	436	443	PF11976	0.345
LIG_SUMO_SIM_par_1	530	536	PF11976	0.345
LIG_SUMO_SIM_par_1	885	890	PF11976	0.420
LIG_SUMO_SIM_par_1	952	958	PF11976	0.440
LIG_TRAF2_1	670	673	PF00917	0.369
LIG_TRAF2_1	895	898	PF00917	0.559
LIG_TRAF2_1	907	910	PF00917	0.448
LIG_TYR_ITIM	160	165	PF00017	0.345
LIG_UBA3_1	189	196	PF00899	0.345
LIG_UBA3_1	62	70	PF00899	0.399
LIG_UBA3_1	711	717	PF00899	0.399
LIG_WRC_WIRS_1	1051	1056	PF05994	0.399
LIG_WW_3	335	339	PF00397	0.498
MOD_CK1_1	1109	1115	PF00069	0.392
MOD_CK1_1	1243	1249	PF00069	0.592
MOD_CK1_1	126	132	PF00069	0.421
MOD_CK1_1	226	232	PF00069	0.345
MOD_CK1_1	569	575	PF00069	0.345
MOD_CK1_1	957	963	PF00069	0.434
MOD_CK2_1	1043	1049	PF00069	0.399
MOD_CK2_1	1058	1064	PF00069	0.399
MOD_CK2_1	158	164	PF00069	0.345
MOD_CK2_1	201	207	PF00069	0.380
MOD_CK2_1	347	353	PF00069	0.442
MOD_CK2_1	426	432	PF00069	0.380
MOD_CK2_1	533	539	PF00069	0.345
MOD_CK2_1	610	616	PF00069	0.459
MOD_CK2_1	667	673	PF00069	0.425
MOD_CK2_1	830	836	PF00069	0.345
MOD_CK2_1	892	898	PF00069	0.537
MOD_CK2_1	904	910	PF00069	0.391
MOD_CK2_1	96	102	PF00069	0.432
MOD_Cter_Amidation	129	132	PF01082	0.335
MOD_GlcNHglycan	1	4	PF01048	0.651
MOD_GlcNHglycan	1204	1207	PF01048	0.354
MOD_GlcNHglycan	218	221	PF01048	0.345
MOD_GlcNHglycan	224	228	PF01048	0.345
MOD_GlcNHglycan	230	233	PF01048	0.345
MOD_GlcNHglycan	349	352	PF01048	0.432
MOD_GlcNHglycan	372	375	PF01048	0.345
MOD_GlcNHglycan	564	567	PF01048	0.345
MOD_GlcNHglycan	586	589	PF01048	0.345
MOD_GlcNHglycan	650	653	PF01048	0.721
MOD_GlcNHglycan	723	726	PF01048	0.372
MOD_GlcNHglycan	734	737	PF01048	0.304
MOD_GlcNHglycan	826	829	PF01048	0.345
MOD_GSK3_1	1170	1177	PF00069	0.345
MOD_GSK3_1	1240	1247	PF00069	0.590
MOD_GSK3_1	142	149	PF00069	0.345
MOD_GSK3_1	167	174	PF00069	0.391
MOD_GSK3_1	185	192	PF00069	0.439
MOD_GSK3_1	216	223	PF00069	0.335
MOD_GSK3_1	343	350	PF00069	0.484
MOD_GSK3_1	562	569	PF00069	0.345
MOD_GSK3_1	628	635	PF00069	0.450
MOD_GSK3_1	758	765	PF00069	0.699
MOD_GSK3_1	824	831	PF00069	0.345
MOD_GSK3_1	858	865	PF00069	0.345
MOD_GSK3_1	90	97	PF00069	0.447
MOD_GSK3_1	950	957	PF00069	0.430
MOD_N-GLC_1	1106	1111	PF02516	0.393
MOD_N-GLC_1	142	147	PF02516	0.345
MOD_N-GLC_1	158	163	PF02516	0.345
MOD_N-GLC_1	370	375	PF02516	0.345
MOD_N-GLC_1	50	55	PF02516	0.399
MOD_N-GLC_1	569	574	PF02516	0.345
MOD_N-GLC_1	628	633	PF02516	0.462
MOD_N-GLC_1	667	672	PF02516	0.463
MOD_N-GLC_1	873	878	PF02516	0.423
MOD_NEK2_1	1192	1197	PF00069	0.383
MOD_NEK2_1	1245	1250	PF00069	0.514
MOD_NEK2_1	142	147	PF00069	0.386
MOD_NEK2_1	185	190	PF00069	0.345
MOD_NEK2_1	238	243	PF00069	0.399
MOD_NEK2_1	347	352	PF00069	0.437
MOD_NEK2_1	355	360	PF00069	0.484
MOD_NEK2_1	439	444	PF00069	0.345
MOD_NEK2_1	452	457	PF00069	0.345
MOD_NEK2_1	571	576	PF00069	0.345
MOD_NEK2_1	63	68	PF00069	0.345
MOD_NEK2_1	721	726	PF00069	0.399
MOD_NEK2_1	758	763	PF00069	0.682
MOD_NEK2_1	773	778	PF00069	0.264
MOD_NEK2_1	880	885	PF00069	0.472
MOD_NEK2_1	963	968	PF00069	0.393
MOD_NEK2_2	1017	1022	PF00069	0.433
MOD_NEK2_2	201	206	PF00069	0.345
MOD_NEK2_2	274	279	PF00069	0.399
MOD_NEK2_2	873	878	PF00069	0.540
MOD_PIKK_1	100	106	PF00454	0.324
MOD_PIKK_1	1165	1171	PF00454	0.345
MOD_PIKK_1	1240	1246	PF00454	0.583
MOD_PIKK_1	452	458	PF00454	0.315
MOD_PIKK_1	63	69	PF00454	0.345
MOD_PIKK_1	90	96	PF00454	0.360
MOD_PK_1	144	150	PF00069	0.345
MOD_PK_1	667	673	PF00069	0.467
MOD_PKA_2	1190	1196	PF00069	0.257
MOD_PKA_2	126	132	PF00069	0.393
MOD_PKA_2	673	679	PF00069	0.322
MOD_PKA_2	904	910	PF00069	0.367
MOD_PKA_2	979	985	PF00069	0.399
MOD_Plk_1	1106	1112	PF00069	0.419
MOD_Plk_1	158	164	PF00069	0.345
MOD_Plk_1	569	575	PF00069	0.345
MOD_Plk_1	667	673	PF00069	0.467
MOD_Plk_1	873	879	PF00069	0.460
MOD_Plk_1	957	963	PF00069	0.434
MOD_Plk_2-3	1124	1130	PF00069	0.399
MOD_Plk_4	1025	1031	PF00069	0.303
MOD_Plk_4	1050	1056	PF00069	0.320
MOD_Plk_4	1174	1180	PF00069	0.399
MOD_Plk_4	185	191	PF00069	0.345
MOD_Plk_4	201	207	PF00069	0.345
MOD_Plk_4	29	35	PF00069	0.345
MOD_Plk_4	343	349	PF00069	0.474
MOD_ProDKin_1	146	152	PF00069	0.345
MOD_ProDKin_1	318	324	PF00069	0.471
MOD_ProDKin_1	455	461	PF00069	0.399
MOD_ProDKin_1	6	12	PF00069	0.468
MOD_ProDKin_1	628	634	PF00069	0.454
MOD_ProDKin_1	828	834	PF00069	0.345
MOD_SUMO_for_1	645	648	PF00179	0.550
MOD_SUMO_rev_2	43	52	PF00179	0.471
MOD_SUMO_rev_2	651	661	PF00179	0.727
TRG_DiLeu_BaEn_1	102	107	PF01217	0.390
TRG_DiLeu_BaEn_1	1148	1153	PF01217	0.373
TRG_DiLeu_BaEn_1	753	758	PF01217	0.652
TRG_DiLeu_BaEn_3	1128	1134	PF01217	0.345
TRG_DiLeu_BaLyEn_6	475	480	PF01217	0.399
TRG_ENDOCYTIC_2	1069	1072	PF00928	0.399
TRG_ENDOCYTIC_2	1110	1113	PF00928	0.345
TRG_ENDOCYTIC_2	1157	1160	PF00928	0.345
TRG_ENDOCYTIC_2	1196	1199	PF00928	0.399
TRG_ENDOCYTIC_2	1216	1219	PF00928	0.140
TRG_ENDOCYTIC_2	157	160	PF00928	0.345
TRG_ENDOCYTIC_2	162	165	PF00928	0.345
TRG_ENDOCYTIC_2	211	214	PF00928	0.345
TRG_ENDOCYTIC_2	239	242	PF00928	0.345
TRG_ENDOCYTIC_2	291	294	PF00928	0.461
TRG_ENDOCYTIC_2	512	515	PF00928	0.345
TRG_ENDOCYTIC_2	612	615	PF00928	0.457
TRG_ENDOCYTIC_2	798	801	PF00928	0.345
TRG_ENDOCYTIC_2	908	911	PF00928	0.442
TRG_ENDOCYTIC_2	924	927	PF00928	0.311
TRG_ER_diArg_1	107	109	PF00400	0.348
TRG_ER_diArg_1	131	133	PF00400	0.398
TRG_ER_diArg_1	337	340	PF00400	0.497
TRG_ER_diArg_1	480	482	PF00400	0.345
TRG_ER_diArg_1	946	949	PF00400	0.539
TRG_Pf-PMV_PEXEL_1	22	27	PF00026	0.399
TRG_Pf-PMV_PEXEL_1	228	233	PF00026	0.345
TRG_Pf-PMV_PEXEL_1	300	304	PF00026	0.414

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7K4	Leptomonas seymouri	87%	100%
A0A0S4ISL0	Bodo saltans	65%	96%
A4H4V2	Leishmania braziliensis	90%	100%
A4HT60	Leishmania infantum	100%	100%
A6H5Y3	Mus musculus	56%	100%
A8XY95	Caenorhabditis briggsae	53%	98%
E9AL19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
O33259	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	31%	100%
P13009	Escherichia coli (strain K12)	53%	100%
P37586	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	53%	100%
Q09582	Caenorhabditis elegans	55%	100%
Q49775	Mycobacterium leprae (strain TN)	31%	100%
Q4JIJ3	Bos taurus	57%	99%
Q4QIT5	Leishmania major	98%	100%
Q54P92	Dictyostelium discoideum	55%	99%
Q55786	Synechocystis sp. (strain PCC 6803 / Kazusa)	32%	100%
Q5E814	Aliivibrio fischeri (strain ATCC 700601 / ES114)	52%	100%
Q7MHB1	Vibrio vulnificus (strain YJ016)	52%	100%
Q87L95	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	53%	100%
Q8DCJ7	Vibrio vulnificus (strain CMCP6)	52%	100%
Q99707	Homo sapiens	57%	99%
Q9AJQ8	Aliivibrio fischeri	52%	100%
Q9I2Q2	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	52%	100%
Q9KUW9	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	53%	100%
Q9Z2Q4	Rattus norvegicus	56%	100%