Protein kinase, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein kinase, putative

Species:

Leishmania donovani

UniProt:

A0A3S5H5R5_LEIDO

TriTrypDb:

LdBPK_060660.1 , LdCL_060011700 , LDHU3_06.0770

Length:

3150

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

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Expansion

Sequence features

A0A3S5H5R5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	6
GO:0006793	phosphorus metabolic process	3	6
GO:0006796	phosphate-containing compound metabolic process	4	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0007165	signal transduction	2	1
GO:0008152	metabolic process	1	6
GO:0009987	cellular process	1	6
GO:0016310	phosphorylation	5	6
GO:0019538	protein metabolic process	3	6
GO:0036211	protein modification process	4	6

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	6
GO:0003824	catalytic activity	1	6
GO:0004672	protein kinase activity	3	6
GO:0005488	binding	1	6
GO:0005524	ATP binding	5	6
GO:0016301	kinase activity	4	6
GO:0016740	transferase activity	2	6
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	6
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	6
GO:0017076	purine nucleotide binding	4	6

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1027	1031	PF00656	0.480
CLV_C14_Caspase3-7	1228	1232	PF00656	0.472
CLV_C14_Caspase3-7	1561	1565	PF00656	0.483
CLV_C14_Caspase3-7	1837	1841	PF00656	0.423
CLV_C14_Caspase3-7	1971	1975	PF00656	0.463
CLV_C14_Caspase3-7	2120	2124	PF00656	0.544
CLV_C14_Caspase3-7	2523	2527	PF00656	0.467
CLV_C14_Caspase3-7	2617	2621	PF00656	0.760
CLV_C14_Caspase3-7	2673	2677	PF00656	0.780
CLV_C14_Caspase3-7	2940	2944	PF00656	0.467

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4H4M9	Leishmania braziliensis	67%	100%
A4HSV5	Leishmania infantum	99%	100%
E9AKU3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	98%
Q4QJ14	Leishmania major	90%	100%

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