MYND_finger_domain-like_protein/GeneDB:LmjF.06.03 00

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MYND finger domain-like protein

Species:

Leishmania donovani

UniProt:

A0A3S5H5P3_LEIDO

TriTrypDb:

LdBPK_060300.1 , LdCL_060008100 , LDHU3_06.0370

Length:

169

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S5H5P3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S5H5P3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	145	149	PF00082	0.321
DEG_SPOP_SBC_1	131	135	PF00917	0.299
DOC_USP7_MATH_1	132	136	PF00917	0.277
DOC_USP7_UBL2_3	156	160	PF12436	0.376
DOC_WW_Pin1_4	114	119	PF00397	0.592
DOC_WW_Pin1_4	164	169	PF00397	0.503
LIG_14-3-3_CanoR_1	129	138	PF00244	0.304
LIG_Clathr_ClatBox_1	103	107	PF01394	0.644
LIG_FHA_1	131	137	PF00498	0.345
LIG_FHA_1	26	32	PF00498	0.626
LIG_FHA_1	62	68	PF00498	0.550
LIG_FHA_2	41	47	PF00498	0.613
LIG_Pex14_2	73	77	PF04695	0.634
LIG_SH2_STAP1	29	33	PF00017	0.572
LIG_SH2_STAT5	102	105	PF00017	0.640
LIG_SH2_STAT5	149	152	PF00017	0.300
LIG_SH3_3	162	168	PF00018	0.360
LIG_TRAF2_1	36	39	PF00917	0.627
LIG_WW_3	77	81	PF00397	0.552
MOD_CK2_1	40	46	PF00069	0.619
MOD_GlcNHglycan	90	93	PF01048	0.541
MOD_N-GLC_2	119	121	PF02516	0.447
MOD_NEK2_1	15	20	PF00069	0.594
MOD_NEK2_1	73	78	PF00069	0.625
MOD_PIKK_1	22	28	PF00454	0.619
MOD_PK_1	148	154	PF00069	0.376
MOD_PKA_2	139	145	PF00069	0.360
MOD_Plk_2-3	46	52	PF00069	0.486
MOD_Plk_4	40	46	PF00069	0.559
MOD_Plk_4	67	73	PF00069	0.641
MOD_ProDKin_1	114	120	PF00069	0.577
MOD_SUMO_rev_2	153	161	PF00179	0.376
TRG_DiLeu_BaLyEn_6	62	67	PF01217	0.587
TRG_ENDOCYTIC_2	149	152	PF00928	0.376
TRG_Pf-PMV_PEXEL_1	101	105	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL36	Leptomonas seymouri	82%	95%
A0A0S4JPC0	Bodo saltans	41%	100%
A4H4J6	Leishmania braziliensis	83%	100%
A4HSS1	Leishmania infantum	100%	100%
E9AKQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QJ49	Leishmania major	96%	99%